HUT64007A - Process for obtaining sennoside a, b and a1 - Google Patents
Process for obtaining sennoside a, b and a1Info
- Publication number
- HUT64007A HUT64007A HU939300506A HU9300506A HUT64007A HU T64007 A HUT64007 A HU T64007A HU 939300506 A HU939300506 A HU 939300506A HU 9300506 A HU9300506 A HU 9300506A HU T64007 A HUT64007 A HU T64007A
- Authority
- HU
- Hungary
- Prior art keywords
- sennosides
- anthrone
- sennoside
- obtaining
- glucosides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- IPQVTOJGNYVQEO-LALZNDFESA-N 9-[(9r)-2-carboxy-4-hydroxy-10-oxo-5-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9h-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9h-anthracene-2-carboxylic acid Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC2=C1C(=O)C1=C(O)C=C(C(O)=O)C=C1C2[C@H]1C2=CC(C(O)=O)=CC(O)=C2C(=O)C2=C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C=CC=C21 IPQVTOJGNYVQEO-LALZNDFESA-N 0.000 title 1
- 229930186851 sennoside Natural products 0.000 abstract 4
- IPQVTOJGNYVQEO-UHFFFAOYSA-N 9-[2-carboxy-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9h-anthracen-9-yl]-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9h-anthracene-2-carboxylic acid Chemical class OC1C(O)C(O)C(CO)OC1OC1=CC=CC2=C1C(=O)C1=C(O)C=C(C(O)=O)C=C1C2C1C2=CC(C(O)=O)=CC(O)=C2C(=O)C2=C(OC3C(C(O)C(O)C(CO)O3)O)C=CC=C21 IPQVTOJGNYVQEO-UHFFFAOYSA-N 0.000 abstract 3
- YDQWDHRMZQUTBA-UHFFFAOYSA-N Aloe emodin Chemical compound C1=CC=C2C(=O)C3=CC(CO)=CC(O)=C3C(=O)C2=C1O YDQWDHRMZQUTBA-UHFFFAOYSA-N 0.000 abstract 2
- 238000000926 separation method Methods 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 229940124513 senna glycoside Drugs 0.000 abstract 1
- IPQVTOJGNYVQEO-KGFNBKMBSA-N sennoside A Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC2=C1C(=O)C1=C(O)C=C(C(O)=O)C=C1[C@@H]2[C@H]1C2=CC(C(O)=O)=CC(O)=C2C(=O)C2=C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C=CC=C21 IPQVTOJGNYVQEO-KGFNBKMBSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4120991A DE4120991A1 (de) | 1991-06-25 | 1991-06-25 | Verfahren zur gewinnung der sennoside a, b und a1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9300506D0 HU9300506D0 (en) | 1993-05-28 |
| HUT64007A true HUT64007A (en) | 1993-11-29 |
| HU210198B HU210198B (en) | 1995-02-28 |
Family
ID=6434719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9300506A HU210198B (en) | 1991-06-25 | 1992-06-24 | Process of extracting sennosides a,b and a1 and of preparing pharmaceutical compositions contg. them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0544886B1 (hu) |
| JP (1) | JP2705733B2 (hu) |
| AT (1) | ATE157984T1 (hu) |
| AU (1) | AU662343B2 (hu) |
| CA (1) | CA2090340C (hu) |
| CZ (1) | CZ281687B6 (hu) |
| DE (2) | DE4120991A1 (hu) |
| DK (1) | DK0544886T3 (hu) |
| ES (1) | ES2110000T3 (hu) |
| FI (1) | FI104902B (hu) |
| GR (1) | GR3024842T3 (hu) |
| HU (1) | HU210198B (hu) |
| IE (1) | IE922048A1 (hu) |
| PL (1) | PL173870B1 (hu) |
| RU (1) | RU2104281C1 (hu) |
| SK (1) | SK23493A3 (hu) |
| WO (1) | WO1993000350A1 (hu) |
| ZA (1) | ZA924646B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI96692C (fi) * | 1993-12-17 | 1996-08-12 | Leiras Oy | Menetelmä sennosidien A ja B valmistamiseksi |
| US20010011131A1 (en) | 1997-07-28 | 2001-08-02 | Luyten Frank P. | DNA molecules encoding cartilage-derived morphogenetic proteins |
| US5560913A (en) * | 1995-01-27 | 1996-10-01 | The Procter & Gamble Company | Pharmaceutical compositions |
| RU2264223C2 (ru) * | 2000-10-23 | 2005-11-20 | Открытое Акционерное Общество "Фармацевтическая Фабрика Санкт-Петербурга" | Микстура слабительная сухая, слабительное средство, препаративная форма микстуры слабительной сухой и способ приготовления микстуры слабительной |
| RU2293720C1 (ru) * | 2005-12-06 | 2007-02-20 | Ооо "Эстеркем" | Способ восстановления ненасыщенных кетонов в насыщенные кетоны |
| ITRM20130294A1 (it) * | 2013-05-16 | 2014-11-17 | Aboca Spa Societa Agricola | Estratti di senna e loro usi |
| CN113624853A (zh) * | 2020-05-07 | 2021-11-09 | 厦门泓益检测有限公司 | 一种基于uplc-ms/ms的减肥产品中泻药成份同时检测方法 |
| CN117224419B (zh) * | 2023-11-14 | 2024-01-30 | 山东第一医科大学(山东省医学科学院) | 番泻苷c在制备皮肤美白淡斑护肤品中的应用及相关产品 |
| FR3157148A1 (fr) * | 2023-12-21 | 2025-06-27 | L'oreal | Procédé d’obtention d’une composition aqueuse à base d’une sennoside, de base forte et d’acide |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB555450A (en) * | 1941-05-13 | 1943-08-24 | Sandoz Ltd | Process for the preparation of active glucosides of senna |
| GB832017A (en) * | 1957-10-02 | 1960-04-06 | Westminster Lab Ltd | Senna preparations |
| DE1617667B1 (de) * | 1966-09-08 | 1970-09-03 | Nattermann A & Cie | Verfahren zur Gewinnung eines sennosideichen Wirkstoffkonzentrates aus Sennesschoten |
| JPS54149813U (hu) * | 1978-04-10 | 1979-10-18 | ||
| FR2422678A1 (fr) * | 1978-04-14 | 1979-11-09 | Synthelabo | Extraction de sennosides |
| DE3200131A1 (de) * | 1982-01-05 | 1983-07-14 | Madaus & Co Dr | "verfahren zur gewinnung von laxativen verbindungen aus sennadroge" |
| FR2594337A1 (fr) * | 1986-02-17 | 1987-08-21 | Oppag Sa | Composition a base de sennosides et procede de preparation de cette composition |
-
1991
- 1991-06-25 DE DE4120991A patent/DE4120991A1/de not_active Ceased
-
1992
- 1992-06-24 PL PL92298140A patent/PL173870B1/pl unknown
- 1992-06-24 DK DK92913646.3T patent/DK0544886T3/da active
- 1992-06-24 AU AU21654/92A patent/AU662343B2/en not_active Ceased
- 1992-06-24 JP JP5501333A patent/JP2705733B2/ja not_active Expired - Lifetime
- 1992-06-24 RU RU93004900/04A patent/RU2104281C1/ru not_active IP Right Cessation
- 1992-06-24 HU HU9300506A patent/HU210198B/hu not_active IP Right Cessation
- 1992-06-24 AT AT92913646T patent/ATE157984T1/de not_active IP Right Cessation
- 1992-06-24 ES ES92913646T patent/ES2110000T3/es not_active Expired - Lifetime
- 1992-06-24 ZA ZA924646A patent/ZA924646B/xx unknown
- 1992-06-24 SK SK23493A patent/SK23493A3/sk unknown
- 1992-06-24 EP EP92913646A patent/EP0544886B1/de not_active Expired - Lifetime
- 1992-06-24 CA CA002090340A patent/CA2090340C/en not_active Expired - Fee Related
- 1992-06-24 DE DE59208889T patent/DE59208889D1/de not_active Expired - Fee Related
- 1992-06-24 WO PCT/EP1992/001428 patent/WO1993000350A1/de not_active Ceased
- 1992-07-01 IE IE204892A patent/IE922048A1/en not_active IP Right Cessation
-
1993
- 1993-02-23 FI FI930790A patent/FI104902B/fi active
- 1993-06-24 CZ CZ93370A patent/CZ281687B6/cs not_active IP Right Cessation
-
1997
- 1997-09-24 GR GR970402481T patent/GR3024842T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ37093A3 (en) | 1996-12-11 |
| AU662343B2 (en) | 1995-08-31 |
| GR3024842T3 (en) | 1998-01-30 |
| WO1993000350A1 (de) | 1993-01-07 |
| DE59208889D1 (de) | 1997-10-16 |
| DK0544886T3 (da) | 1997-10-13 |
| IE922048A1 (en) | 1992-12-30 |
| PL173870B1 (pl) | 1998-05-29 |
| RU2104281C1 (ru) | 1998-02-10 |
| CA2090340A1 (en) | 1992-12-26 |
| AU2165492A (en) | 1993-01-25 |
| ZA924646B (en) | 1993-03-31 |
| CZ281687B6 (cs) | 1996-12-11 |
| FI930790A0 (fi) | 1993-02-23 |
| EP0544886B1 (de) | 1997-09-10 |
| JPH06502191A (ja) | 1994-03-10 |
| FI930790L (fi) | 1993-02-23 |
| EP0544886A1 (de) | 1993-06-09 |
| FI104902B (fi) | 2000-04-28 |
| PL298140A1 (en) | 1993-11-02 |
| HU210198B (en) | 1995-02-28 |
| DE4120991A1 (de) | 1993-01-07 |
| ES2110000T3 (es) | 1998-02-01 |
| JP2705733B2 (ja) | 1998-01-28 |
| HU9300506D0 (en) | 1993-05-28 |
| CA2090340C (en) | 1998-08-18 |
| SK23493A3 (en) | 1993-07-07 |
| ATE157984T1 (de) | 1997-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |