ZA924646B - Process for obtaining sennosides a,b,and a1 - Google Patents
Process for obtaining sennosides a,b,and a1Info
- Publication number
- ZA924646B ZA924646B ZA924646A ZA924646A ZA924646B ZA 924646 B ZA924646 B ZA 924646B ZA 924646 A ZA924646 A ZA 924646A ZA 924646 A ZA924646 A ZA 924646A ZA 924646 B ZA924646 B ZA 924646B
- Authority
- ZA
- South Africa
- Prior art keywords
- sennosides
- anthrone
- obtaining
- glucosides
- concerns
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention concerns a method of extracting sennosides A, B and A1. The method comprises the following steps: a sennoside mixture is reduced to the corresponding anthrone-8-glucosides, the aloe-emodin components are removed by liquid-liquid separation of the anthrone-8-glucosides, and the rheine-9-anthrone-8-glucoside obtained after the separation step is oxidized again to sennosides A, B and A1. The invention also concerns sennosides A, B and A1 obtained by this method and pharmaceutical agents containing them.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4120991A DE4120991A1 (en) | 1991-06-25 | 1991-06-25 | PROCESS FOR OBTAINING SENNOSIDES A, B AND A1 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA924646B true ZA924646B (en) | 1993-03-31 |
Family
ID=6434719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA924646A ZA924646B (en) | 1991-06-25 | 1992-06-24 | Process for obtaining sennosides a,b,and a1 |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0544886B1 (en) |
JP (1) | JP2705733B2 (en) |
AT (1) | ATE157984T1 (en) |
AU (1) | AU662343B2 (en) |
CA (1) | CA2090340C (en) |
CZ (1) | CZ281687B6 (en) |
DE (2) | DE4120991A1 (en) |
DK (1) | DK0544886T3 (en) |
ES (1) | ES2110000T3 (en) |
FI (1) | FI104902B (en) |
GR (1) | GR3024842T3 (en) |
HU (1) | HU210198B (en) |
IE (1) | IE922048A1 (en) |
PL (1) | PL173870B1 (en) |
RU (1) | RU2104281C1 (en) |
SK (1) | SK23493A3 (en) |
WO (1) | WO1993000350A1 (en) |
ZA (1) | ZA924646B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI96692C (en) * | 1993-12-17 | 1996-08-12 | Leiras Oy | Process for producing Sennocide A and B |
US20010011131A1 (en) | 1997-07-28 | 2001-08-02 | Luyten Frank P. | DNA molecules encoding cartilage-derived morphogenetic proteins |
US5560913A (en) * | 1995-01-27 | 1996-10-01 | The Procter & Gamble Company | Pharmaceutical compositions |
ITRM20130294A1 (en) * | 2013-05-16 | 2014-11-17 | Aboca Spa Societa Agricola | SENNA EXTRACTS AND THEIR USES |
CN113624853A (en) * | 2020-05-07 | 2021-11-09 | 厦门泓益检测有限公司 | Method for simultaneously detecting cathartic components in weight-reducing product based on UPLC-MS/MS |
CN117224419B (en) * | 2023-11-14 | 2024-01-30 | 山东第一医科大学(山东省医学科学院) | Application of sennoside C in preparing skin whitening and spot-fading skin care product and related product |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB555450A (en) * | 1941-05-13 | 1943-08-24 | Sandoz Ltd | Process for the preparation of active glucosides of senna |
GB832017A (en) * | 1957-10-02 | 1960-04-06 | Westminster Lab Ltd | Senna preparations |
DE1617667B1 (en) * | 1966-09-08 | 1970-09-03 | Nattermann A & Cie | Process for the production of a sennosid-rich active ingredient concentrate from sennessee pods |
JPS54149813U (en) * | 1978-04-10 | 1979-10-18 | ||
DE3200131A1 (en) * | 1982-01-05 | 1983-07-14 | Madaus & Co Dr | "METHOD FOR OBTAINING LAXATIVE COMPOUNDS FROM SENNADROGE" |
FR2594337A1 (en) * | 1986-02-17 | 1987-08-21 | Oppag Sa | Sennoside-based composition and process for preparing this composition |
-
1991
- 1991-06-25 DE DE4120991A patent/DE4120991A1/en not_active Ceased
-
1992
- 1992-06-24 SK SK23493A patent/SK23493A3/en unknown
- 1992-06-24 AU AU21654/92A patent/AU662343B2/en not_active Ceased
- 1992-06-24 ES ES92913646T patent/ES2110000T3/en not_active Expired - Lifetime
- 1992-06-24 CA CA002090340A patent/CA2090340C/en not_active Expired - Fee Related
- 1992-06-24 HU HU9300506A patent/HU210198B/en not_active IP Right Cessation
- 1992-06-24 DE DE59208889T patent/DE59208889D1/en not_active Expired - Fee Related
- 1992-06-24 PL PL92298140A patent/PL173870B1/en unknown
- 1992-06-24 WO PCT/EP1992/001428 patent/WO1993000350A1/en active IP Right Grant
- 1992-06-24 RU RU93004900/04A patent/RU2104281C1/en not_active IP Right Cessation
- 1992-06-24 DK DK92913646.3T patent/DK0544886T3/en active
- 1992-06-24 EP EP92913646A patent/EP0544886B1/en not_active Expired - Lifetime
- 1992-06-24 ZA ZA924646A patent/ZA924646B/en unknown
- 1992-06-24 JP JP5501333A patent/JP2705733B2/en not_active Expired - Lifetime
- 1992-06-24 AT AT92913646T patent/ATE157984T1/en not_active IP Right Cessation
- 1992-07-01 IE IE204892A patent/IE922048A1/en not_active IP Right Cessation
-
1993
- 1993-02-23 FI FI930790A patent/FI104902B/en active
- 1993-06-24 CZ CZ93370A patent/CZ281687B6/en not_active IP Right Cessation
-
1997
- 1997-09-24 GR GR970402481T patent/GR3024842T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
HU210198B (en) | 1995-02-28 |
WO1993000350A1 (en) | 1993-01-07 |
JP2705733B2 (en) | 1998-01-28 |
HU9300506D0 (en) | 1993-05-28 |
SK23493A3 (en) | 1993-07-07 |
JPH06502191A (en) | 1994-03-10 |
IE922048A1 (en) | 1992-12-30 |
FI104902B (en) | 2000-04-28 |
CA2090340A1 (en) | 1992-12-26 |
HUT64007A (en) | 1993-11-29 |
CA2090340C (en) | 1998-08-18 |
GR3024842T3 (en) | 1998-01-30 |
RU2104281C1 (en) | 1998-02-10 |
DE4120991A1 (en) | 1993-01-07 |
AU662343B2 (en) | 1995-08-31 |
DK0544886T3 (en) | 1997-10-13 |
PL298140A1 (en) | 1993-11-02 |
CZ37093A3 (en) | 1996-12-11 |
EP0544886B1 (en) | 1997-09-10 |
DE59208889D1 (en) | 1997-10-16 |
CZ281687B6 (en) | 1996-12-11 |
ES2110000T3 (en) | 1998-02-01 |
ATE157984T1 (en) | 1997-09-15 |
FI930790A0 (en) | 1993-02-23 |
EP0544886A1 (en) | 1993-06-09 |
AU2165492A (en) | 1993-01-25 |
PL173870B1 (en) | 1998-05-29 |
FI930790A (en) | 1993-02-23 |
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