HUT61587A - Process for preparing lipopeptide deacylase - Google Patents

Process for preparing lipopeptide deacylase

Info

Publication number
HUT61587A
HUT61587A HU911897A HU189791A HUT61587A HU T61587 A HUT61587 A HU T61587A HU 911897 A HU911897 A HU 911897A HU 189791 A HU189791 A HU 189791A HU T61587 A HUT61587 A HU T61587A
Authority
HU
Hungary
Prior art keywords
enzyme
deacylase
lipid
preparing
lipopeptide deacylase
Prior art date
Application number
HU911897A
Other languages
English (en)
Other versions
HU215232B (hu
HU911897D0 (en
Inventor
Adam Joseph Kreuzman
Wu-Kuang Yeh
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU911897D0 publication Critical patent/HU911897D0/hu
Publication of HUT61587A publication Critical patent/HUT61587A/hu
Publication of HU215232B publication Critical patent/HU215232B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
HU911897A 1990-06-07 1991-06-06 Eljárás lipopeptid-deaciláz előállítására HU215232B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53439490A 1990-06-07 1990-06-07

Publications (3)

Publication Number Publication Date
HU911897D0 HU911897D0 (en) 1991-12-30
HUT61587A true HUT61587A (en) 1993-01-28
HU215232B HU215232B (hu) 1998-11-30

Family

ID=24129856

Family Applications (1)

Application Number Title Priority Date Filing Date
HU911897A HU215232B (hu) 1990-06-07 1991-06-06 Eljárás lipopeptid-deaciláz előállítására

Country Status (14)

Country Link
US (1) US5573936A (hu)
EP (1) EP0460882B1 (hu)
JP (1) JP2994486B2 (hu)
KR (1) KR0169994B1 (hu)
AT (1) ATE140728T1 (hu)
CA (1) CA2043762C (hu)
DE (1) DE69121018T2 (hu)
DK (1) DK0460882T3 (hu)
ES (1) ES2089133T3 (hu)
GR (1) GR3021292T3 (hu)
HU (1) HU215232B (hu)
IE (1) IE75885B1 (hu)
IL (1) IL98349A (hu)
TW (1) TW197471B (hu)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
EP1854877B1 (en) * 1996-03-08 2012-02-08 Astellas Pharma Inc. Process for the deacylation of cyclic lipopeptides
EP1666587A1 (en) * 1996-06-13 2006-06-07 Astellas Pharma Inc. Cyclic lipopeptide acylase
US6361988B1 (en) 1997-03-25 2002-03-26 California Institute Of Technology ECB deacylase mutants
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
US5936074A (en) * 1997-04-17 1999-08-10 Eli Lilly And Company Teicoplanin deacylation process and product
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
IL143563A0 (en) 1998-12-09 2002-04-21 Lilly Co Eli Purification of echinocandin cyclopeptide compounds
WO2000052037A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin/carbohydrate complexes
ATE338060T1 (de) 1999-03-03 2006-09-15 Lilly Co Eli Bildung und anionenaustausch von inneren kristallinen ammoniumsalzen des echinocandins b
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
EP1156782B1 (en) 1999-03-03 2005-05-04 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
HUP0202315A2 (en) * 1999-07-15 2002-10-28 Lilly Co Eli Process for deacylation of lipodepsipeptides
BR0017028A (pt) * 1999-12-15 2003-01-07 Cubist Pharm Inc Lipopepìdeos como agentes antibacterianos
US7408025B2 (en) * 1999-12-15 2008-08-05 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
EP2295444A3 (en) 1999-12-15 2011-03-23 Cubist Pharmaceutical Inc. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
NZ531493A (en) * 2001-08-06 2006-03-31 Cubist Pharm Inc Novel depsipeptides and process for preparing same, useful in the treatment of bacterial infection
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
DE102004060750A1 (de) 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Deacylierung von Lipopeptiden
CN102325787B (zh) * 2008-12-22 2014-05-28 丘比斯特药物股份有限公司 治疗革兰氏阳性感染的新的抗菌剂
US9394340B2 (en) * 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
IN2015DN01633A (hu) 2012-09-24 2015-07-03 Dsm Sinochem Pharm Nl Bv
KR101425108B1 (ko) * 2012-09-25 2014-07-31 동국제약 주식회사 탈아실화된 환상 리포펩티드의 제조방법
CN108410929B (zh) * 2018-05-30 2024-01-26 博瑞生物医药（苏州）股份有限公司 阿尼芬净前体的制备方法
CN109593809A (zh) * 2018-12-07 2019-04-09 成都雅途生物技术有限公司 一种固定化微生物酶转化棘白菌素b的方法
CN113215185B (zh) * 2021-04-22 2022-04-29 浙江工业大学 一种用于重组表达棘白菌素b脱酰基酶的重组基因序列

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei

Also Published As

Publication number Publication date
DE69121018D1 (de) 1996-08-29
HU215232B (hu) 1998-11-30
TW197471B (hu) 1993-01-01
KR0169994B1 (ko) 1999-02-01
US5573936A (en) 1996-11-12
DK0460882T3 (da) 1996-08-26
IL98349A (en) 1995-05-26
EP0460882A2 (en) 1991-12-11
KR920000919A (ko) 1992-01-29
GR3021292T3 (en) 1997-01-31
IE75885B1 (en) 1997-09-24
IL98349A0 (en) 1992-07-15
CA2043762C (en) 2001-05-29
ES2089133T3 (es) 1996-10-01
ATE140728T1 (de) 1996-08-15
EP0460882A3 (en) 1992-04-22
CA2043762A1 (en) 1991-12-08
HU911897D0 (en) 1991-12-30
IE911939A1 (en) 1991-12-18
JPH04228072A (ja) 1992-08-18
DE69121018T2 (de) 1996-12-19
JP2994486B2 (ja) 1999-12-27
EP0460882B1 (en) 1996-07-24

Similar Documents

Publication Publication Date Title
HUT61587A (en) Process for preparing lipopeptide deacylase
DK163520C (da) Substitueret androsta-1,4-dien-3,17-dioner, fremgangsmaade til fremstilling deraf, praeparater indeholdende saadanne forbindelser samt anvendelsen af disse til fremstilling af farmaceutiske praeparater
GB9804632D0 (en) Virus preparations and methods
DE69332879D1 (de) Technetium-99-markierte peptide zur visualisierung vom entzuendungen
ATE171216T1 (de) Expression und reinigung von rekombinantem, löslichem gewebefaktor
DK0464140T3 (da) Aktivt adhæsionspeptid
AU4052389A (en) Derivatized glass supports for peptide and protein sequencing
AU4421585A (en) Potent thymopentin analogs
GR900100621A (en) Polypeptide analogs of apolipoprotein e diagnostic systems and methods using the analogs
JPH02500022U (hu)
EP0459564A3 (en) Process for reduction of echinocandin type cyclohexapeptide compounds
Gomi et al. S-adenosylhomocysteinase from rat liver. Amino acid sequences of the peptides containing active site cysteine residues modified by treatment with 5'-p-fluorosulfonylbenzoyladenosine.
MY119366A (en) A process for the preparation of factor ix from biological sources
AP9100296A0 (en) Peptides and analogues and mixtures thereof for detecting antibodies to HTLV-1 and HTLV11 viruses.
ES2195409T3 (es) Purificacion de moleculas.
AU5339390A (en) Peptides and antibodies for the detection of ngf (nerve growth factor) and/or precursors thereof
NZ224873A (en) Chromatographic purification process for lipopeptide or glycopeptide fermentation products
AU7796291A (en) High affinity antibodies to small peptides
SANTIS Spherical cap harmonic analysis of local gravity field
AU8125991A (en) Apparatus for blending gaseous or vaporous substances
EP0351790A3 (de) Verfahren zur Bestimmung von Fructosamin
EP0389318A3 (en) Procedure for helping navigation and improved terrestrial navigation system
DK412389D0 (da) Fremgangsmaade til udvinding af oprenset epi protein fra en fermenteringsoploesning
Lopez-Trascasa et al. Isolation and characterization of a biologically active C2 derived oligopeptide
BLUFORD Applying science in space to practical needs

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee