HUT57263A - Process for producing bacterial vectors - Google Patents
Process for producing bacterial vectors Download PDFInfo
- Publication number
- HUT57263A HUT57263A HU91958A HU95891A HUT57263A HU T57263 A HUT57263 A HU T57263A HU 91958 A HU91958 A HU 91958A HU 95891 A HU95891 A HU 95891A HU T57263 A HUT57263 A HU T57263A
- Authority
- HU
- Hungary
- Prior art keywords
- plasmid
- msp
- lactis
- gene
- dna
- Prior art date
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- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
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- 238000004255 ion exchange chromatography Methods 0.000 description 1
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- 101150066555 lacZ gene Proteins 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
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- 108010054155 lysyllysine Proteins 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
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- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
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- 108010009719 mutanolysin Proteins 0.000 description 1
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- 210000004498 neuroglial cell Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
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- 108010051242 phenylalanylserine Proteins 0.000 description 1
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- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
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- 238000012216 screening Methods 0.000 description 1
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- 230000009962 secretion pathway Effects 0.000 description 1
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- 239000002002 slurry Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
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- 229960000553 somatostatin Drugs 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
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- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- IEKWPPTXWFKANS-UHFFFAOYSA-K trichlorocobalt Chemical compound Cl[Co](Cl)Cl IEKWPPTXWFKANS-UHFFFAOYSA-K 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- 239000002753 trypsin inhibitor Substances 0.000 description 1
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- 230000002792 vascular Effects 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909006400A GB9006400D0 (en) | 1990-03-22 | 1990-03-22 | Bacterial vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU910958D0 HU910958D0 (en) | 1991-10-28 |
| HUT57263A true HUT57263A (en) | 1991-11-28 |
Family
ID=10673033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU91958A HUT57263A (en) | 1990-03-22 | 1991-03-21 | Process for producing bacterial vectors |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5559007A (OSRAM) |
| EP (1) | EP0449770B1 (OSRAM) |
| JP (1) | JPH04211384A (OSRAM) |
| KR (1) | KR910016930A (OSRAM) |
| AR (1) | AR245504A1 (OSRAM) |
| AT (1) | ATE174055T1 (OSRAM) |
| AU (1) | AU643511B2 (OSRAM) |
| BR (1) | BR9101137A (OSRAM) |
| CA (1) | CA2038706A1 (OSRAM) |
| DE (1) | DE69130544T2 (OSRAM) |
| DK (1) | DK0449770T3 (OSRAM) |
| ES (1) | ES2125864T3 (OSRAM) |
| FI (1) | FI911367A7 (OSRAM) |
| GB (1) | GB9006400D0 (OSRAM) |
| HU (1) | HUT57263A (OSRAM) |
| IE (1) | IE910948A1 (OSRAM) |
| MX (1) | MX25027A (OSRAM) |
| NO (1) | NO911138L (OSRAM) |
| NZ (1) | NZ237506A (OSRAM) |
| PT (1) | PT97081B (OSRAM) |
| TW (1) | TW213488B (OSRAM) |
| ZA (1) | ZA912114B (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286361A (en) * | 1992-10-19 | 1994-02-15 | Regents Of The University Of California | Magnetically attached sputter targets |
| AU2149495A (en) * | 1995-04-11 | 1996-10-30 | Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno | Method for the construction of vectors for lactic acid bacte ria like lactobacillus such that the bacteria can efficientl y express, secrete and display proteins at the surface |
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| EP0925364B1 (en) * | 1996-09-06 | 2002-10-23 | Bioteknologisk Institut | A lactic acid bacterial regulatable expression system |
| EP1239032A1 (en) * | 2001-03-02 | 2002-09-11 | Société des Produits Nestlé S.A. | Lactic acid bacteria as agents for treating and preventing allergy |
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| JP2005529622A (ja) | 2002-06-19 | 2005-10-06 | ヴェーイーベー・ヴェーゼットウェー | 腸吸収を促進するための方法および手段 |
| CA2506031A1 (en) * | 2002-11-15 | 2004-06-03 | Vib Vzw | Self-containing lactobacillus strain comprising a thya mutation and therapeutic applications thereof |
| ES2596855T3 (es) | 2005-11-29 | 2017-01-12 | Intrexon Actobiotics Nv | Inducción de tolerancia mucosa a antígenos |
| RU2495129C2 (ru) | 2007-01-12 | 2013-10-10 | Актогеникс Н.В. | ПРОМОТОРЫ Lactococcus И ИХ ПРИМЕНЕНИЕ: |
| JP2010516269A (ja) | 2007-01-25 | 2010-05-20 | アクトジェニックス・エヌブイ | 抗原の粘膜送達による免疫疾患の治療 |
| JP5126879B2 (ja) * | 2007-07-13 | 2013-01-23 | 独立行政法人海洋研究開発機構 | 新規ｄｎａ断片およびそれを含む組換えベクター、それらによって形質転換された形質転換体、ならびにそれらの利用 |
| DK3181682T3 (da) | 2008-09-29 | 2021-07-05 | Intrexon Actobiotics Nv | Reduceret kolonisering af mikrober på slimhinden |
| JP5897459B2 (ja) | 2009-04-30 | 2016-03-30 | イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ | 乳酸菌のフリーズドライのための凍結保護剤 |
| EP2275527A1 (en) | 2009-07-17 | 2011-01-19 | ActoGeniX NV | Animal component-free culture medium for bacterial fermentation |
| EP3192873A1 (en) | 2009-09-29 | 2017-07-19 | Intrexon Actobiotics NV | Lactobacillus and streptococcus promoters and uses thereof |
| CA2802994A1 (en) | 2010-06-17 | 2011-12-22 | The United States Of America As Represented By The Secretary, National I Nstitutes Of Health | Compositions and methods for treating inflammatory conditions |
| RU2644346C2 (ru) | 2011-06-01 | 2018-02-08 | Интрексон Актобиотикс Н.В. | Система полицистронной экспрессии для бактерий |
| DK2758512T3 (en) | 2011-09-23 | 2018-07-23 | Intrexon Actobiotics Nv | MODIFIED GRAM POSITIVE BACTERIES AND APPLICATIONS THEREOF |
| EP2758513B1 (en) | 2011-09-23 | 2018-05-16 | Intrexon Actobiotics NV | Modified gram positive bacteria and uses thereof |
| JP7292877B2 (ja) | 2016-01-14 | 2023-06-19 | イントレクソン・アクトバイオテイクス・エヌブイ | １型糖尿病を処置するための組成物および方法 |
| US20200095566A1 (en) * | 2017-03-22 | 2020-03-26 | Agency For Science, Technology And Research | Protein Expression Construct and Methods Thereof |
| CN116144690A (zh) * | 2022-08-23 | 2023-05-23 | 江西省科学院微生物研究所(江西省流域生态研究所) | 一种大肠杆菌与乳酸菌的穿梭载体pDXA及构建方法与应用 |
| WO2025233675A1 (en) | 2024-05-10 | 2025-11-13 | Institut Pasteur | Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings |
| WO2025253171A1 (en) | 2024-06-04 | 2025-12-11 | Institut Pasteur | Characterization of viruses associated with the zoonotic fish-borne oncogenic liver flukes and applications thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8400687A (nl) | 1984-03-02 | 1985-10-01 | Unilever Nv | Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit. |
| ATE64956T1 (de) | 1984-06-14 | 1991-07-15 | Ciba Geigy Ag | Verfahren zur herstellung von thrombininhibitoren. |
| NL8503316A (nl) * | 1985-11-29 | 1987-06-16 | Stichting Nl I Zuivelonderzoek | Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen. |
| EP0316677A3 (en) | 1987-11-13 | 1990-04-25 | Miles Inc. | Method for cloning in lactic acid bacteria |
| NL9000753A (nl) * | 1990-03-30 | 1991-10-16 | Nl Zuivelonderzoek Inst | Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten. |
-
1990
- 1990-03-22 GB GB909006400A patent/GB9006400D0/en active Pending
-
1991
- 1991-03-13 DE DE69130544T patent/DE69130544T2/de not_active Expired - Fee Related
- 1991-03-13 EP EP91810167A patent/EP0449770B1/en not_active Expired - Lifetime
- 1991-03-13 ES ES91810167T patent/ES2125864T3/es not_active Expired - Lifetime
- 1991-03-13 AT AT91810167T patent/ATE174055T1/de not_active IP Right Cessation
- 1991-03-13 DK DK91810167T patent/DK0449770T3/da active
- 1991-03-15 AU AU73558/91A patent/AU643511B2/en not_active Ceased
- 1991-03-20 JP JP3056889A patent/JPH04211384A/ja active Pending
- 1991-03-20 TW TW080102185A patent/TW213488B/zh active
- 1991-03-20 CA CA002038706A patent/CA2038706A1/en not_active Abandoned
- 1991-03-20 PT PT97081A patent/PT97081B/pt not_active IP Right Cessation
- 1991-03-20 FI FI911367A patent/FI911367A7/fi not_active Application Discontinuation
- 1991-03-20 NZ NZ237506A patent/NZ237506A/en unknown
- 1991-03-21 HU HU91958A patent/HUT57263A/hu unknown
- 1991-03-21 IE IE094891A patent/IE910948A1/en unknown
- 1991-03-21 ZA ZA912114A patent/ZA912114B/xx unknown
- 1991-03-21 NO NO91911138A patent/NO911138L/no unknown
- 1991-03-21 KR KR1019910004439A patent/KR910016930A/ko not_active Ceased
- 1991-03-22 AR AR91319296A patent/AR245504A1/es active
- 1991-03-22 BR BR919101137A patent/BR9101137A/pt unknown
- 1991-03-22 MX MX2502791A patent/MX25027A/es unknown
-
1994
- 1994-01-21 US US08/186,222 patent/US5559007A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR910016930A (ko) | 1991-11-05 |
| ATE174055T1 (de) | 1998-12-15 |
| TW213488B (OSRAM) | 1993-09-21 |
| AU643511B2 (en) | 1993-11-18 |
| CA2038706A1 (en) | 1991-09-23 |
| PT97081B (pt) | 1998-07-31 |
| BR9101137A (pt) | 1991-11-05 |
| AR245504A1 (es) | 1994-01-31 |
| EP0449770B1 (en) | 1998-12-02 |
| IE910948A1 (en) | 1991-09-25 |
| FI911367A0 (fi) | 1991-03-20 |
| PT97081A (pt) | 1991-11-29 |
| US5559007A (en) | 1996-09-24 |
| AU7355891A (en) | 1991-10-03 |
| DK0449770T3 (da) | 1999-06-23 |
| DE69130544D1 (de) | 1999-01-14 |
| NZ237506A (en) | 1992-12-23 |
| EP0449770A3 (en) | 1992-07-01 |
| FI911367L (fi) | 1991-09-23 |
| HU910958D0 (en) | 1991-10-28 |
| GB9006400D0 (en) | 1990-05-23 |
| NO911138L (no) | 1991-09-23 |
| DE69130544T2 (de) | 1999-04-29 |
| ES2125864T3 (es) | 1999-03-16 |
| ZA912114B (en) | 1992-01-29 |
| FI911367A7 (fi) | 1991-09-23 |
| NO911138D0 (no) | 1991-03-21 |
| EP0449770A2 (en) | 1991-10-02 |
| MX25027A (es) | 1993-12-01 |
| JPH04211384A (ja) | 1992-08-03 |
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