HUT50334A - Process for producing arylpiperazinyl-alkilenephenyl-p-heterocycluc compounds, pharmaceutically acceptable acid addition salts thereof and pharmaceutical compositions comprising the compounds as active ingredient - Google Patents
Process for producing arylpiperazinyl-alkilenephenyl-p-heterocycluc compounds, pharmaceutically acceptable acid addition salts thereof and pharmaceutical compositions comprising the compounds as active ingredientInfo
- Publication number
- HUT50334A HUT50334A HU88748A HU74888A HUT50334A HU T50334 A HUT50334 A HU T50334A HU 88748 A HU88748 A HU 88748A HU 74888 A HU74888 A HU 74888A HU T50334 A HUT50334 A HU T50334A
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- heterocycluc
- alkilenephenyl
- arylpiperazinyl
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8700340 | 1987-02-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT50334A true HUT50334A (en) | 1990-01-29 |
| HU207731B HU207731B (en) | 1993-05-28 |
Family
ID=22202287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU88748A HU207731B (en) | 1987-02-17 | 1988-02-16 | Process for producing aryl-piperazinyl-alkylene-phenyl-p-heterocyclic compounds, pharmaceutically acceptable acid additional salts and pharmaceutical compositions containing them as active components |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0279598B1 (hu) |
| JP (1) | JPH0699405B2 (hu) |
| KR (1) | KR900004126B1 (hu) |
| CN (1) | CN1015627B (hu) |
| AP (1) | AP88A (hu) |
| AR (1) | AR245125A1 (hu) |
| AT (1) | ATE94537T1 (hu) |
| AU (1) | AU583761B2 (hu) |
| CA (1) | CA1312080C (hu) |
| CS (1) | CS272783B2 (hu) |
| DD (1) | DD272080A5 (hu) |
| DE (1) | DE3884007T2 (hu) |
| DK (1) | DK170878B1 (hu) |
| EG (1) | EG18635A (hu) |
| ES (1) | ES2058249T3 (hu) |
| FI (1) | FI91752C (hu) |
| HU (1) | HU207731B (hu) |
| IE (1) | IE61258B1 (hu) |
| IL (1) | IL85368A0 (hu) |
| IN (1) | IN171858B (hu) |
| MA (1) | MA21183A1 (hu) |
| MX (1) | MX174210B (hu) |
| MY (1) | MY103210A (hu) |
| NO (1) | NO170582C (hu) |
| NZ (1) | NZ223530A (hu) |
| PL (1) | PL157118B1 (hu) |
| PT (1) | PT86766B (hu) |
| SU (1) | SU1634136A3 (hu) |
| YU (1) | YU46624B (hu) |
| ZA (1) | ZA881064B (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX173362B (es) * | 1987-03-02 | 1994-02-23 | Pfizer | Compuestos de piperazinil heterociclicos y procedimiento para su preparacion |
| SE8803429D0 (sv) * | 1988-09-28 | 1988-09-28 | Pharmacia Ab | Novel pyridyl- and pyrimidyl derivatives |
| US5166156A (en) * | 1989-12-20 | 1992-11-24 | Adir Et Compagnie | Naphthyl piperazines useful as 5-HT1A receptor ligands |
| FR2655988B1 (fr) * | 1989-12-20 | 1994-05-20 | Adir Cie | Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5162321A (en) * | 1989-12-20 | 1992-11-10 | Adir Et Compagnie | 1-naphthyl piperazines useful as 5-HT1A receptor ligands |
| US5166157A (en) * | 1989-12-20 | 1992-11-24 | Adir Et Compagnie | Naphthyl piperazines useful as 5-HT1A receptor ligands |
| US5162324A (en) * | 1989-12-20 | 1992-11-10 | Adir Et Compagnie | Naphyl piperazines useful as 5-HT1A receptor ligands |
| HUP9802492A3 (en) * | 1995-06-06 | 1999-10-28 | Hoechst Marion Roussel Inc Cin | Benzisoxazole and indazole derivatives as antipsychotic agents, process for their preparation and pharmaceutical compositions containing the same |
| GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
| SK89398A3 (en) | 1995-12-29 | 1998-11-04 | Boehringer Ingelheim Pharma | Phenyl thiazole derivatives with anti herpes virus properties |
| US6288091B1 (en) | 1995-12-29 | 2001-09-11 | Boehringer Ingelheim Ltd. | Antiherpes virus compounds and methods for their preparation and use |
| WO1999001420A1 (fr) | 1997-07-03 | 1999-01-14 | Taito Co., Ltd. | Procede de preparation de derives d'acide 2-aminomalonique, et intermediaires utilises dans ce procede |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2927924A (en) * | 1958-04-03 | 1960-03-08 | Lilly Co Eli | Novel phenethyl-substituted piperazines |
| GB948766A (en) * | 1959-10-20 | 1964-02-05 | May & Baker Ltd | Trifluoromethylphenylpiperazine derivatives |
| DE1695410A1 (de) * | 1967-04-20 | 1971-04-08 | Merck Patent Gmbh | Verfahren zur Herstellung von 1-(Thiazolyl-5-alkyl)-4-(pyridyl-2)-piperazinen |
| JPS5910675B2 (ja) * | 1976-03-22 | 1984-03-10 | ウェルファイド株式会社 | アラルキルアミン誘導体 |
| US4411901A (en) * | 1981-12-23 | 1983-10-25 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
| US4619930A (en) * | 1985-01-16 | 1986-10-28 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use |
| JPH075579B2 (ja) * | 1986-09-01 | 1995-01-25 | 吉富製薬株式会社 | アミノチアゾ−ル化合物 |
-
1987
- 1987-02-17 MX MX010428A patent/MX174210B/es unknown
-
1988
- 1988-01-27 IN IN64/DEL/88A patent/IN171858B/en unknown
- 1988-02-09 IL IL85368A patent/IL85368A0/xx not_active IP Right Cessation
- 1988-02-12 ES ES88301171T patent/ES2058249T3/es not_active Expired - Lifetime
- 1988-02-12 DE DE88301171T patent/DE3884007T2/de not_active Expired - Fee Related
- 1988-02-12 EP EP88301171A patent/EP0279598B1/en not_active Expired - Lifetime
- 1988-02-12 AT AT88301171T patent/ATE94537T1/de not_active IP Right Cessation
- 1988-02-13 KR KR1019880001454A patent/KR900004126B1/ko not_active IP Right Cessation
- 1988-02-15 CA CA000558900A patent/CA1312080C/en not_active Expired - Fee Related
- 1988-02-15 MA MA21420A patent/MA21183A1/fr unknown
- 1988-02-15 PT PT86766A patent/PT86766B/pt not_active IP Right Cessation
- 1988-02-15 PL PL1988270653A patent/PL157118B1/pl unknown
- 1988-02-15 CN CN88100986A patent/CN1015627B/zh not_active Expired
- 1988-02-15 JP JP63032593A patent/JPH0699405B2/ja not_active Expired - Fee Related
- 1988-02-16 FI FI880716A patent/FI91752C/fi active IP Right Grant
- 1988-02-16 IE IE42088A patent/IE61258B1/en not_active IP Right Cessation
- 1988-02-16 HU HU88748A patent/HU207731B/hu unknown
- 1988-02-16 ZA ZA881064A patent/ZA881064B/xx unknown
- 1988-02-16 NZ NZ223530A patent/NZ223530A/xx unknown
- 1988-02-16 DK DK078888A patent/DK170878B1/da not_active IP Right Cessation
- 1988-02-16 NO NO880667A patent/NO170582C/no not_active IP Right Cessation
- 1988-02-16 MY MYPI88000161A patent/MY103210A/en unknown
- 1988-02-16 DD DD88312959A patent/DD272080A5/de not_active IP Right Cessation
- 1988-02-16 CS CS96488A patent/CS272783B2/cs not_active IP Right Cessation
- 1988-02-16 AR AR88310090A patent/AR245125A1/es active
- 1988-02-16 AP APAP/P/1988/000082A patent/AP88A/en active
- 1988-02-16 YU YU30388A patent/YU46624B/sh unknown
- 1988-02-16 AU AU11740/88A patent/AU583761B2/en not_active Ceased
- 1988-02-16 SU SU4355194A patent/SU1634136A3/ru active
- 1988-02-17 EG EG9388A patent/EG18635A/xx active
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