HUT49882A - Process for producing new spiro square brackets open chroman-4,4'-imidazolidine square brackets closed derivatives and pharmaceutical compositions comprising these compounds as active ingredient - Google Patents
Process for producing new spiro square brackets open chroman-4,4'-imidazolidine square brackets closed derivatives and pharmaceutical compositions comprising these compounds as active ingredientInfo
- Publication number
- HUT49882A HUT49882A HU893124A HU312486A HUT49882A HU T49882 A HUT49882 A HU T49882A HU 893124 A HU893124 A HU 893124A HU 312486 A HU312486 A HU 312486A HU T49882 A HUT49882 A HU T49882A
- Authority
- HU
- Hungary
- Prior art keywords
- square brackets
- compounds
- chroman
- imidazolidine
- active ingredient
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/738,924 US4575507A (en) | 1985-05-29 | 1985-05-29 | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT49882A true HUT49882A (en) | 1989-11-28 |
HU199845B HU199845B (en) | 1990-03-28 |
Family
ID=24970055
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU862249A HU196060B (en) | 1985-05-29 | 1986-05-28 | Process for producing new spiro-imidazolidine derivatives |
HU893124A HU199845B (en) | 1985-05-29 | 1986-05-28 | Process for producing new spiro/chroman-4,4'-imidazolidine derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
HU872418A HUT49879A (en) | 1985-05-29 | 1986-05-28 | Process for producing new 1',2'-dihydrospiro square brackets open imidazolidine-4,4'(3'h)-quinoline square brackets closed derivatives and pharmaceutical compositions comprising these compounds as active ingredient |
HU893127A HU893127D0 (en) | 1985-05-29 | 1987-05-28 | Process for the preparation of novel spiro-(imidazolidino-naphtaline) derivatives and pharmaceutical compositions containing such compounds as active ingredient |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU862249A HU196060B (en) | 1985-05-29 | 1986-05-28 | Process for producing new spiro-imidazolidine derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU872418A HUT49879A (en) | 1985-05-29 | 1986-05-28 | Process for producing new 1',2'-dihydrospiro square brackets open imidazolidine-4,4'(3'h)-quinoline square brackets closed derivatives and pharmaceutical compositions comprising these compounds as active ingredient |
HU893127A HU893127D0 (en) | 1985-05-29 | 1987-05-28 | Process for the preparation of novel spiro-(imidazolidino-naphtaline) derivatives and pharmaceutical compositions containing such compounds as active ingredient |
Country Status (21)
Country | Link |
---|---|
US (1) | US4575507A (hu) |
EP (1) | EP0203791B1 (hu) |
JP (1) | JPS61277671A (hu) |
KR (1) | KR890001548B1 (hu) |
AT (1) | ATE46332T1 (hu) |
AU (1) | AU560429B2 (hu) |
DD (5) | DD264214A5 (hu) |
DE (1) | DE3665584D1 (hu) |
DK (1) | DK248886A (hu) |
EG (1) | EG17859A (hu) |
ES (2) | ES8800228A1 (hu) |
FI (1) | FI862251A (hu) |
GR (1) | GR861388B (hu) |
HU (4) | HU196060B (hu) |
IL (1) | IL78954A (hu) |
NO (1) | NO862123L (hu) |
NZ (1) | NZ216334A (hu) |
PH (1) | PH22213A (hu) |
PL (5) | PL147400B1 (hu) |
PT (1) | PT82650B (hu) |
ZA (1) | ZA863934B (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU198212B (en) * | 1984-07-20 | 1989-08-28 | Pfizer | Process for production of spiro-imidasolones |
US4762839A (en) * | 1985-06-06 | 1988-08-09 | Tanabe Seiyaku Co., Ltd. | Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications |
JPS63132889A (ja) * | 1986-11-21 | 1988-06-04 | Tanabe Seiyaku Co Ltd | キナゾリノン誘導体 |
EP0306525A4 (en) * | 1987-03-20 | 1991-04-24 | Alcon Laboratories Inc | Use of aldose reductase inhibitors to enhance insulin sensitivity in diabetes mellitus |
US5004751A (en) * | 1987-08-28 | 1991-04-02 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
US5202339A (en) * | 1987-08-28 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
WO1990002126A1 (en) * | 1988-08-24 | 1990-03-08 | Mochida Pharmaceutical Co., Ltd. | Hydantoin derivatives |
US5068332A (en) * | 1990-10-12 | 1991-11-26 | American Home Products Corporation | Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors |
US8326636B2 (en) * | 2008-01-16 | 2012-12-04 | Canyon Ip Holdings Llc | Using a physical phenomenon detector to control operation of a speech recognition engine |
CN104080775A (zh) * | 2012-02-09 | 2014-10-01 | 勃林格殷格翰国际有限公司 | 立体选择性合成1,4-保护的9-羟基-5-氧代-1,4-二氮杂-螺[5.5]十一烷的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
US4117230A (en) | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
ATE23046T1 (de) * | 1982-11-10 | 1986-11-15 | Pfizer | Sorbinil durch optische aufspaltung mit aminopinanderivaten. |
ZA839023B (en) * | 1982-12-06 | 1985-07-31 | Pfizer | Spiro-3-hetero-azolones for treatment of diabetic complications |
US4556670A (en) | 1982-12-06 | 1985-12-03 | Pfizer Inc. | Spiro-3-hetero-azolones for treatment of diabetic complications |
DE3561198D1 (en) * | 1984-03-23 | 1988-01-28 | Pfizer | Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications |
US4762838A (en) | 1985-08-30 | 1988-08-09 | Pfizer Inc. | Quinazolin-4(3H)-one derivatives as anticoccidial agents |
-
1985
- 1985-05-29 US US06/738,924 patent/US4575507A/en not_active Expired - Lifetime
-
1986
- 1986-05-23 AT AT86303925T patent/ATE46332T1/de not_active IP Right Cessation
- 1986-05-23 EP EP86303925A patent/EP0203791B1/en not_active Expired
- 1986-05-23 DE DE8686303925T patent/DE3665584D1/de not_active Expired
- 1986-05-27 PL PL1986266366A patent/PL147400B1/pl unknown
- 1986-05-27 PL PL1986259739A patent/PL146020B1/pl unknown
- 1986-05-27 DD DD86309079A patent/DD264214A5/de not_active IP Right Cessation
- 1986-05-27 ES ES555375A patent/ES8800228A1/es not_active Expired
- 1986-05-27 PL PL1986266364A patent/PL147398B1/pl unknown
- 1986-05-27 DD DD86309078A patent/DD264213A5/de not_active IP Right Cessation
- 1986-05-27 PL PL1986266363A patent/PL147397B1/pl unknown
- 1986-05-27 PL PL1986266365A patent/PL147399B1/pl unknown
- 1986-05-27 ZA ZA863934A patent/ZA863934B/xx unknown
- 1986-05-27 PT PT82650A patent/PT82650B/pt not_active IP Right Cessation
- 1986-05-27 DD DD86290626A patent/DD251972A5/de not_active IP Right Cessation
- 1986-05-27 DD DD86309080A patent/DD264215A5/de not_active IP Right Cessation
- 1986-05-28 HU HU862249A patent/HU196060B/hu unknown
- 1986-05-28 HU HU893124A patent/HU199845B/hu unknown
- 1986-05-28 NO NO862123A patent/NO862123L/no unknown
- 1986-05-28 HU HU872418A patent/HUT49879A/hu unknown
- 1986-05-28 DK DK248886A patent/DK248886A/da not_active Application Discontinuation
- 1986-05-28 KR KR8604182A patent/KR890001548B1/ko not_active IP Right Cessation
- 1986-05-28 AU AU58012/86A patent/AU560429B2/en not_active Ceased
- 1986-05-28 GR GR861388A patent/GR861388B/el unknown
- 1986-05-28 EG EG317/86A patent/EG17859A/xx active
- 1986-05-28 FI FI862251A patent/FI862251A/fi not_active Application Discontinuation
- 1986-05-28 IL IL78954A patent/IL78954A/xx unknown
- 1986-05-28 NZ NZ216334A patent/NZ216334A/xx unknown
- 1986-05-29 JP JP61124608A patent/JPS61277671A/ja active Pending
- 1986-05-29 PH PH33830A patent/PH22213A/en unknown
-
1987
- 1987-02-13 ES ES557391A patent/ES8801830A1/es not_active Expired
- 1987-05-28 HU HU893127A patent/HU893127D0/hu unknown
- 1987-11-16 DD DD87309077A patent/DD273258A5/de not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 |