HUP9903747A2 - Új eljárás mometazon-furoát előállítására - Google Patents

Új eljárás mometazon-furoát előállítására

Info

Publication number
HUP9903747A2
HUP9903747A2 HU9903747A HUP9903747A HUP9903747A2 HU P9903747 A2 HUP9903747 A2 HU P9903747A2 HU 9903747 A HU9903747 A HU 9903747A HU P9903747 A HUP9903747 A HU P9903747A HU P9903747 A2 HUP9903747 A2 HU P9903747A2
Authority
HU
Hungary
Prior art keywords
new process
preparation
mometasone furoate
hydroxyl group
furoate
Prior art date
Application number
HU9903747A
Other languages
English (en)
Inventor
Joao Bandarra
William Heggie
Original Assignee
Hovione Inter Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Inter Ltd. filed Critical Hovione Inter Ltd.
Publication of HU9903747D0 publication Critical patent/HU9903747D0/hu
Publication of HUP9903747A2 publication Critical patent/HUP9903747A2/hu
Publication of HUP9903747A3 publication Critical patent/HUP9903747A3/hu
Publication of HU227494B1 publication Critical patent/HU227494B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány egy új eljárás mometazon-l7-furoátelőállítására a 17-helyzetű hidroxilcsoport közvetlen észterezésével,a szabad 11-hidroxilcsoport előzőleg történő megvédése nélkül. Atalálmány szerinti előállított vegyület szteroid vegyület ésgyulladásos betegségek kezelésére használható. Ó
HU9903747A 1999-08-02 1999-10-21 New process for the preparation of mometasone furoate HU227494B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT102343A PT102343B (pt) 1999-08-02 1999-08-02 Processo para a preparacao de furoato mometasona

Publications (4)

Publication Number Publication Date
HU9903747D0 HU9903747D0 (en) 1999-12-28
HUP9903747A2 true HUP9903747A2 (hu) 2001-05-28
HUP9903747A3 HUP9903747A3 (en) 2001-07-30
HU227494B1 HU227494B1 (en) 2011-07-28

Family

ID=20085881

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903747A HU227494B1 (en) 1999-08-02 1999-10-21 New process for the preparation of mometasone furoate

Country Status (22)

Country Link
US (1) US6177560B1 (hu)
EP (1) EP1074558B1 (hu)
JP (1) JP3746174B2 (hu)
KR (1) KR100640066B1 (hu)
CN (1) CN1149222C (hu)
AT (1) ATE229970T1 (hu)
AU (1) AU765592B2 (hu)
CA (1) CA2295455C (hu)
DE (1) DE69904585T2 (hu)
DK (1) DK1074558T3 (hu)
ES (1) ES2189354T3 (hu)
HR (1) HRP990341B1 (hu)
HU (1) HU227494B1 (hu)
IL (1) IL133752A (hu)
NO (1) NO321154B1 (hu)
NZ (1) NZ500555A (hu)
PL (1) PL191103B1 (hu)
PT (1) PT102343B (hu)
RU (1) RU2208616C2 (hu)
SI (1) SI1074558T1 (hu)
UA (1) UA60333C2 (hu)
ZA (1) ZA996758B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
EP1790754A1 (de) * 2005-11-24 2007-05-30 Siemens Aktiengesellschaft Schichtsystem mit Gadolinium-Mischkristall-Pyrochlorphase
US8021742B2 (en) * 2006-12-15 2011-09-20 Siemens Energy, Inc. Impact resistant thermal barrier coating system
PL3111926T3 (pl) 2009-05-29 2020-06-29 Pearl Therapeutics, Inc. Kompozycje, sposoby i układy do dostarczania dwóch lub większej liczby środków czynnych do układu oddechowego
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
PT105139B (pt) * 2010-06-01 2013-01-29 Hovione Farmaciencia S A Método para a monofluorometilação de substratos orgânicos para preparação de compostos orgânicos biologicamente activos
US20140275517A1 (en) 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
MX2015016058A (es) 2013-05-22 2016-12-20 Pearl Therapeutics Inc Composiciones, metodos y sistemas para el suministro por via respiratoria de tres o mas agentes activos.
CN105481933B (zh) * 2015-12-25 2017-09-19 山东京卫制药有限公司 一种合成糠酸莫米松的方法
CN105566437B (zh) * 2015-12-30 2018-07-20 山东京卫制药有限公司 一种8dm衍生物及利用其合成糠酸莫米松的方法
CN107266518B (zh) * 2016-04-08 2021-03-30 天津金耀集团有限公司 一种糠酸莫米松晶型及其制备方法
WO2023283441A1 (en) 2021-07-09 2023-01-12 Astrazeneca Pharmaceuticals Lp Compositions, methods and systems for aerosol drug delivery
WO2023119093A1 (en) 2021-12-20 2023-06-29 Astrazeneca Ab Compositions, methods and systems for aerosol drug delivery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE8790T1 (de) * 1981-02-02 1984-08-15 Schering Corporation Aromatische heterocyclische steroidester, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
PT923599E (pt) * 1996-06-28 2002-06-28 Schering Corp Processo para a preparacao de 17-esteres de 9alfa,21-di-halopregnano-11beta,17alfadiol-20-onas
US5886200A (en) * 1996-07-01 1999-03-23 Schering Corporation Process for the preparation of 17-esters of 9 α, 21-dihalo-pregnane-11 β, 17 α-diol-20-ones

Also Published As

Publication number Publication date
PT102343A (pt) 2001-02-28
CA2295455C (en) 2008-03-25
US6177560B1 (en) 2001-01-23
CN1149222C (zh) 2004-05-12
IL133752A0 (en) 2001-04-30
HU227494B1 (en) 2011-07-28
EP1074558A1 (en) 2001-02-07
ES2189354T3 (es) 2003-07-01
NO995225D0 (no) 1999-10-26
JP2001048897A (ja) 2001-02-20
SI1074558T1 (en) 2003-04-30
PL191103B1 (pl) 2006-03-31
HUP9903747A3 (en) 2001-07-30
KR100640066B1 (ko) 2006-10-31
HU9903747D0 (en) 1999-12-28
PT102343B (pt) 2003-11-28
CN1282744A (zh) 2001-02-07
NO995225L (no) 2001-02-05
NO321154B1 (no) 2006-03-27
HRP990341B1 (en) 2003-10-31
DE69904585D1 (de) 2003-01-30
ATE229970T1 (de) 2003-01-15
HRP990341A2 (en) 2001-04-30
KR20010020094A (ko) 2001-03-15
IL133752A (en) 2004-02-19
UA60333C2 (uk) 2003-10-15
EP1074558B1 (en) 2002-12-18
JP3746174B2 (ja) 2006-02-15
AU765592B2 (en) 2003-09-25
RU2208616C2 (ru) 2003-07-20
AU5602499A (en) 2001-02-08
ZA996758B (en) 2000-08-30
DK1074558T3 (da) 2003-04-07
DE69904585T2 (de) 2003-05-15
CA2295455A1 (en) 2001-02-02
PL336452A1 (en) 2001-02-12
NZ500555A (en) 2000-11-24

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