ATE229518T1 - Cis-3,4-chromanderivate zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen - Google Patents

Cis-3,4-chromanderivate zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen

Info

Publication number
ATE229518T1
ATE229518T1 AT97910264T AT97910264T ATE229518T1 AT E229518 T1 ATE229518 T1 AT E229518T1 AT 97910264 T AT97910264 T AT 97910264T AT 97910264 T AT97910264 T AT 97910264T AT E229518 T1 ATE229518 T1 AT E229518T1
Authority
AT
Austria
Prior art keywords
syndromes
prevention
treatment
related diseases
estrogen
Prior art date
Application number
AT97910264T
Other languages
English (en)
Inventor
Poul Jacobsen
Svend Treppendahl
Bury Paul Stanley
Anders Kanstrup
Christiansen Lise Brown
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE229518T1 publication Critical patent/ATE229518T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97910264T 1996-10-28 1997-10-28 Cis-3,4-chromanderivate zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen ATE229518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119796 1996-10-28
PCT/DK1997/000483 WO1998018776A1 (en) 1996-10-28 1997-10-28 Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Publications (1)

Publication Number Publication Date
ATE229518T1 true ATE229518T1 (de) 2002-12-15

Family

ID=8102066

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97910264T ATE229518T1 (de) 1996-10-28 1997-10-28 Cis-3,4-chromanderivate zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen

Country Status (12)

Country Link
EP (1) EP0937060B1 (de)
JP (1) JP2001502708A (de)
AT (1) ATE229518T1 (de)
AU (1) AU4772097A (de)
CA (1) CA2269974A1 (de)
DE (1) DE69717843T2 (de)
DK (1) DK0937060T3 (de)
ES (1) ES2188908T3 (de)
IL (1) IL129616A0 (de)
NO (1) NO992003L (de)
WO (1) WO1998018776A1 (de)
ZA (1) ZA979647B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1120162C (zh) * 1996-12-13 2003-09-03 中外制药株式会社 新的苯并吡喃衍生物
CN1155589C (zh) * 1998-12-30 2004-06-30 信号药品公司 调节雌激素受体的化合物
AU1888101A (en) * 1999-12-13 2001-06-18 Chugai Seiyaku Kabushiki Kaisha 3-methyl-chroman and -thiochroman derivatives
KR20010055765A (ko) * 1999-12-13 2001-07-04 이경하 3-메틸-크로만 또는 티오크로만 유도체
KR20010055766A (ko) * 1999-12-13 2001-07-04 이경하 3-메틸-크로만 또는 티오크로만 유도체의 금속염
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
US7601855B2 (en) 2004-09-21 2009-10-13 Novogen Research Pty Ltd Substituted chroman derivatives, medicaments and use in therapy
ES2516067T3 (es) * 2004-09-21 2014-10-30 Mei Pharma, Inc. Derivados de cromano sustituidos, medicamentos y utilización en terapia
EP2580210B1 (de) 2010-06-10 2017-03-01 Seragon Pharmaceuticals, Inc. Östrogenrezeptormodulatoren und verwendungen davon
WO2012061413A2 (en) 2010-11-01 2012-05-10 Marshall Edwards, Inc. Isoflavonoid compositions and methods for the treatment of cancer
US9187460B2 (en) * 2011-12-14 2015-11-17 Seragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
ES2877712T3 (es) 2015-02-02 2021-11-17 Mei Pharma Inc Terapias combinadas para su uso en el tratamiento del cáncer de mama

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
HUP9702244A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for manufacture of a pharmaceutical composition for treatment or prophylaxis of gynaecological disorders

Also Published As

Publication number Publication date
DK0937060T3 (da) 2003-04-07
NO992003D0 (no) 1999-04-27
NO992003L (no) 1999-06-25
EP0937060B1 (de) 2002-12-11
ZA979647B (en) 1998-04-28
DE69717843D1 (de) 2003-01-23
WO1998018776A1 (en) 1998-05-07
DE69717843T2 (de) 2003-09-25
ES2188908T3 (es) 2003-07-01
CA2269974A1 (en) 1998-05-07
EP0937060A1 (de) 1999-08-25
AU4772097A (en) 1998-05-22
IL129616A0 (en) 2000-02-29
JP2001502708A (ja) 2001-02-27

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