DK0937060T3 - Nye cis-3,4-chroman-derivater, der er nyttige i forebyggelsen eller behandlingen af østrogen-relaterede sygdomme eller syndromer - Google Patents

Nye cis-3,4-chroman-derivater, der er nyttige i forebyggelsen eller behandlingen af østrogen-relaterede sygdomme eller syndromer

Info

Publication number
DK0937060T3
DK0937060T3 DK97910264T DK97910264T DK0937060T3 DK 0937060 T3 DK0937060 T3 DK 0937060T3 DK 97910264 T DK97910264 T DK 97910264T DK 97910264 T DK97910264 T DK 97910264T DK 0937060 T3 DK0937060 T3 DK 0937060T3
Authority
DK
Denmark
Prior art keywords
syndromes
prevention
treatment
related diseases
estrogen
Prior art date
Application number
DK97910264T
Other languages
English (en)
Inventor
Poul Jacobsen
Svend Treppendahl
Bury Paul Stanley
Anders Kanstrup
Christiansen Lise Brown
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0937060T3 publication Critical patent/DK0937060T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DK97910264T 1996-10-28 1997-10-28 Nye cis-3,4-chroman-derivater, der er nyttige i forebyggelsen eller behandlingen af østrogen-relaterede sygdomme eller syndromer DK0937060T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119796 1996-10-28
PCT/DK1997/000483 WO1998018776A1 (en) 1996-10-28 1997-10-28 Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Publications (1)

Publication Number Publication Date
DK0937060T3 true DK0937060T3 (da) 2003-04-07

Family

ID=8102066

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97910264T DK0937060T3 (da) 1996-10-28 1997-10-28 Nye cis-3,4-chroman-derivater, der er nyttige i forebyggelsen eller behandlingen af østrogen-relaterede sygdomme eller syndromer

Country Status (12)

Country Link
EP (1) EP0937060B1 (da)
JP (1) JP2001502708A (da)
AT (1) ATE229518T1 (da)
AU (1) AU4772097A (da)
CA (1) CA2269974A1 (da)
DE (1) DE69717843T2 (da)
DK (1) DK0937060T3 (da)
ES (1) ES2188908T3 (da)
IL (1) IL129616A0 (da)
NO (1) NO992003L (da)
WO (1) WO1998018776A1 (da)
ZA (1) ZA979647B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998025916A1 (en) * 1996-12-13 1998-06-18 C & C Research Laboratories Novel benzopyran derivatives
KR100615757B1 (ko) * 1998-12-30 2006-08-25 시그날 파마소티칼 아이엔씨 에스트로겐 수용체를 조절하는 화합물 및 방법
US6552069B1 (en) * 1999-12-13 2003-04-22 Chugai Seiyaku Kabushiki Kaisha 3-methyl-chroman and -thiochroman derivatives
KR20010055765A (ko) * 1999-12-13 2001-07-04 이경하 3-메틸-크로만 또는 티오크로만 유도체
KR20010055766A (ko) * 1999-12-13 2001-07-04 이경하 3-메틸-크로만 또는 티오크로만 유도체의 금속염
ATE532777T1 (de) 2004-09-21 2011-11-15 Marshall Edwards Inc Substituierte chromanderivate, medikamente und anwendungen in der therapie
ES2377073T3 (es) * 2004-09-21 2012-03-22 Marshall Edwards, Inc. Derivados de cromano sustituidos, medicamentos y utilización en terapia
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
ES2627692T3 (es) 2010-06-10 2017-07-31 Aragon Pharmaceuticals, Inc. Moduladores de receptores de estrógenos y usos de los mismos
JP6013349B2 (ja) 2010-11-01 2016-10-25 メイ ファーマ, インク.Mei Pharma, Inc. 癌の処置のためのイソフラボノイド化合物および方法
WO2013090829A1 (en) 2011-12-14 2013-06-20 Aragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
ES2877712T3 (es) 2015-02-02 2021-11-17 Mei Pharma Inc Terapias combinadas para su uso en el tratamiento del cáncer de mama

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
HUP9702244A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for manufacture of a pharmaceutical composition for treatment or prophylaxis of gynaecological disorders

Also Published As

Publication number Publication date
WO1998018776A1 (en) 1998-05-07
IL129616A0 (en) 2000-02-29
JP2001502708A (ja) 2001-02-27
ZA979647B (en) 1998-04-28
DE69717843T2 (de) 2003-09-25
EP0937060A1 (en) 1999-08-25
EP0937060B1 (en) 2002-12-11
NO992003D0 (no) 1999-04-27
ATE229518T1 (de) 2002-12-15
AU4772097A (en) 1998-05-22
ES2188908T3 (es) 2003-07-01
DE69717843D1 (de) 2003-01-23
CA2269974A1 (en) 1998-05-07
NO992003L (no) 1999-06-25

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