HUP9900961A2 - VIP-analóg szintézise - Google Patents

VIP-analóg szintézise

Info

Publication number
HUP9900961A2
HUP9900961A2 HU9900961A HUP9900961A HUP9900961A2 HU P9900961 A2 HUP9900961 A2 HU P9900961A2 HU 9900961 A HU9900961 A HU 9900961A HU P9900961 A HUP9900961 A HU P9900961A HU P9900961 A2 HUP9900961 A2 HU P9900961A2
Authority
HU
Hungary
Prior art keywords
synthesis
vip analog
vip
analog
peptide
Prior art date
Application number
HU9900961A
Other languages
English (en)
Inventor
David Robert Bolin
Waleed Danho
Arthur M. Felix
Original Assignee
F.Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag. filed Critical F.Hoffmann-La Roche Ag.
Publication of HUP9900961A2 publication Critical patent/HUP9900961A2/hu
Publication of HUP9900961A3 publication Critical patent/HUP9900961A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Regulating Braking Force (AREA)
  • Hydrogen, Water And Hydrids (AREA)
  • Catalysts (AREA)
  • Networks Using Active Elements (AREA)
  • Reduction Or Emphasis Of Bandwidth Of Signals (AREA)

Abstract

A találmány új szintetikűs eljárásra vőnatkőzik az (I) képletű Ac(1-31)-NH2 vazőaktív intesztinális peptid analóg előállítására, négyvédett peptid fragmens kapcsőlása útján. ŕ
HU9900961A 1996-02-09 1997-01-29 Synthesis of vip analog HUP9900961A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1142596P 1996-02-09 1996-02-09

Publications (2)

Publication Number Publication Date
HUP9900961A2 true HUP9900961A2 (hu) 1999-07-28
HUP9900961A3 HUP9900961A3 (en) 2001-06-28

Family

ID=21750320

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900961A HUP9900961A3 (en) 1996-02-09 1997-01-29 Synthesis of vip analog

Country Status (15)

Country Link
US (2) US6080837A (hu)
EP (1) EP0879246B1 (hu)
JP (1) JP2000504676A (hu)
KR (1) KR100493795B1 (hu)
CN (1) CN1186355C (hu)
AT (1) ATE328004T1 (hu)
AU (1) AU722895B2 (hu)
BR (1) BR9707409A (hu)
CZ (1) CZ294779B6 (hu)
DE (1) DE69735991D1 (hu)
HU (1) HUP9900961A3 (hu)
MX (1) MX9806099A (hu)
NO (1) NO983626D0 (hu)
NZ (1) NZ330885A (hu)
WO (1) WO1997029126A1 (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE328004T1 (de) * 1996-02-09 2006-06-15 Hoffmann La Roche Herstellung eines vip-analogen
FR2775902B1 (fr) * 1998-03-13 2001-05-11 Assist Publ Hopitaux De Paris Utilisation d'analogues du vip dans la prevention et le traitement des lesions cerebrales du nouveau-ne humain
ES2245505T3 (es) * 1998-03-23 2006-01-01 Trimeris Inc. Metodos y composiciones para la sintesis de peptidos (t-20).
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
CN101229363A (zh) 2000-11-28 2008-07-30 蒙多生物技术许可股份公司 具有血管活性肠肽的生物学活性的用于治疗肺动脉和小动脉高压的化合物
US20060241028A1 (en) 2002-06-10 2006-10-26 Dorian Bevec Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
KR100451432B1 (ko) * 2002-07-12 2004-10-06 강충경 Ｔ-20 펩타이드의 생물학적 제조방법
WO2006023358A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
KR20090027239A (ko) * 2006-07-06 2009-03-16 에프. 호프만-라 로슈 아게 혈관작용성 장 펩티드의 유사체
ES2870914T3 (es) 2009-08-14 2021-10-28 Phasebio Pharmaceuticals Inc Péptidos intestinales vasoactivos modificados
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
ES2822598T3 (es) 2015-02-09 2021-05-04 Phasebio Pharmaceuticals Inc Métodos y composiciones para tratar enfermedades y trastornos musculares
CN110317257B (zh) * 2019-06-03 2023-10-31 吉尔生化（上海）有限公司 一种辛卡利特的固液相合成法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237046A (en) * 1979-04-27 1980-12-02 Miklos Bodanszky Polypeptides and methods of preparation
WO1991004041A1 (en) * 1989-09-15 1991-04-04 Rutgers, The State University Of New Jersey Process for inducing analgesia, peptides and therapeutic compositions
AU656230B2 (en) * 1991-10-11 1995-01-27 F. Hoffmann-La Roche Ag Cyclic vasoactive peptides
JPH0616694A (ja) * 1992-07-01 1994-01-25 Sato Seiyaku Kk カルシトニンの製造法
ES2051647B1 (es) * 1992-12-10 1995-01-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.
ATE328004T1 (de) * 1996-02-09 2006-06-15 Hoffmann La Roche Herstellung eines vip-analogen

Also Published As

Publication number Publication date
NO983626L (no) 1998-08-07
EP0879246A1 (en) 1998-11-25
CZ294779B6 (cs) 2005-03-16
EP0879246B1 (en) 2006-05-31
CZ251698A3 (cs) 1998-11-11
KR19990082403A (ko) 1999-11-25
MX9806099A (es) 1998-10-31
DE69735991D1 (de) 2006-07-06
BR9707409A (pt) 1999-04-13
US6316593B1 (en) 2001-11-13
KR100493795B1 (ko) 2005-09-09
WO1997029126A1 (en) 1997-08-14
NZ330885A (en) 2000-02-28
CN1210543A (zh) 1999-03-10
AU722895B2 (en) 2000-08-10
JP2000504676A (ja) 2000-04-18
CN1186355C (zh) 2005-01-26
ATE328004T1 (de) 2006-06-15
US6080837A (en) 2000-06-27
HUP9900961A3 (en) 2001-06-28
AU1596397A (en) 1997-08-28
NO983626D0 (no) 1998-08-07

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Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal