HUP9900523A2 - Eljárás 2-(2-metil-fenil)-3-metoxi-akrilsav-metil-észter előállítására - Google Patents

Eljárás 2-(2-metil-fenil)-3-metoxi-akrilsav-metil-észter előállítására

Info

Publication number
HUP9900523A2
HUP9900523A2 HU9900523A HUP9900523A HUP9900523A2 HU P9900523 A2 HUP9900523 A2 HU P9900523A2 HU 9900523 A HU9900523 A HU 9900523A HU P9900523 A HUP9900523 A HU P9900523A HU P9900523 A2 HUP9900523 A2 HU P9900523A2
Authority
HU
Hungary
Prior art keywords
methylphenyl
formula
methyl ester
acid methyl
alkali metal
Prior art date
Application number
HU9900523A
Other languages
English (en)
Inventor
Michael Keil
Josef Wahl
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of HUP9900523A2 publication Critical patent/HUP9900523A2/hu
Publication of HUP9900523A3 publication Critical patent/HUP9900523A3/hu
Publication of HU224530B1 publication Critical patent/HU224530B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/34—Migration of groups in the molecule

Abstract

A találmány tárgya eljárás az (I) képletű 2-(2-metil-fenil)-3-metőxi-akrilsav-metil-észter előállítására a (II) képletű (2-metil-fenil)-ecetsav-metil-észter inert őldószerben, bázis jelenlétében végzettfőrmilezésével, majd a keletkező (III) általánős képletű enőlát -,ahől M+ alkálifém-katiőn - metilezésével. A találmány szerintieljárásban inert őldószerként szerves aprőtikűs dipőlárős őldószert,előnyösen N-metil-pirrőlidőnt, bázisként alkálifém-alkőhőlátőkat,különösen nátriűm-metanőlátőt, metilezőszerként alkil-halőgenideketvagy dimetil-szűlfátőt alkalmaznak. Az eljárás hőzama magas, éstúlnyőmórészt a kívánatős E-izőmer keletkezik. A 2-(2-metil-fenil)-3-metőxi-akrilsav-metil-észter főntős gyógyszerhatóanyagők kiindűlásianyaga. ŕ
HU9900523A 1996-02-17 1997-02-17 Eljárás 2-(2-metil-fenil)-3-metoxi-akrilsav-metil-észter előállítására HU224530B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19605901A DE19605901A1 (de) 1996-02-17 1996-02-17 Verfahren zur Herstellung von 2-(2-Methylphenyl)-3-methoxyacrylsäure -methylester
PCT/EP1997/000728 WO1997030020A1 (de) 1996-02-17 1997-02-17 Verfahren zur herstellung von 2-(2-methylphenyl)-3-methoxyacrylsäure-methylester

Publications (3)

Publication Number Publication Date
HUP9900523A2 true HUP9900523A2 (hu) 1999-06-28
HUP9900523A3 HUP9900523A3 (en) 1999-11-29
HU224530B1 HU224530B1 (hu) 2005-10-28

Family

ID=7785669

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900523A HU224530B1 (hu) 1996-02-17 1997-02-17 Eljárás 2-(2-metil-fenil)-3-metoxi-akrilsav-metil-észter előállítására

Country Status (24)

Country Link
US (1) US6162945A (hu)
EP (1) EP0888280B1 (hu)
JP (1) JP2000504707A (hu)
KR (1) KR100460018B1 (hu)
CN (1) CN1129573C (hu)
AR (1) AR005878A1 (hu)
AT (1) ATE204850T1 (hu)
AU (1) AU709159B2 (hu)
BR (1) BR9707444A (hu)
CA (1) CA2245547C (hu)
CZ (1) CZ184498A3 (hu)
DE (2) DE19605901A1 (hu)
DK (1) DK0888280T3 (hu)
ES (1) ES2162242T3 (hu)
GR (1) GR3036530T3 (hu)
HU (1) HU224530B1 (hu)
IL (1) IL124226A (hu)
MX (1) MX9803844A (hu)
NZ (1) NZ330387A (hu)
PL (1) PL186292B1 (hu)
PT (1) PT888280E (hu)
SK (1) SK102898A3 (hu)
WO (1) WO1997030020A1 (hu)
ZA (1) ZA971252B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114408D0 (en) * 2001-06-13 2001-08-08 Syngenta Ltd Chemical process
IL180134A0 (en) * 2006-12-17 2007-07-04 David Ovadia Process for the preparation of substituted cyanophenoxy-pyrimidinyloxy -phenyl acrylate derivatives
IL181125A0 (en) 2007-02-01 2007-07-04 Maktheshim Chemical Works Ltd Polymorphs of 3-(e)-2-{2-[6-(2-
CN100564362C (zh) * 2007-10-24 2009-12-02 北京颖泰嘉和科技股份有限公司 嘧菌酯及其类似物的制备方法
CN106008367A (zh) * 2015-11-20 2016-10-12 江苏长青农化股份有限公司 嘧菌酯合成方法
EP3252381B1 (en) 2016-05-31 2021-08-04 Samsung Electronics Co., Ltd. Cooking oven and controlling method thereof
CN108299197B (zh) * 2018-02-06 2021-08-03 荆楚理工学院 一种3-烷氧基丙烯酸酯合成方法
CN109748792A (zh) * 2018-12-24 2019-05-14 江苏中旗科技股份有限公司 啶氧菌酯中间体2-（2-氯甲基苯基）-3-甲氧基丙烯酸甲酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ213630A (en) * 1984-10-19 1990-02-26 Ici Plc Acrylic acid derivatives and fungicidal compositions
ES2052696T5 (es) * 1987-02-09 2000-03-01 Zeneca Ltd Fungicidas.
DK0378308T3 (da) * 1989-01-11 1996-08-05 Agrevo Uk Ltd Acrylat-fungicider
DE4026904A1 (de) * 1990-08-25 1992-02-27 Bayer Ag Verfahren zur herstellung von 3-alkoxy-2-heteroazolyl-amino-acrylsaeureestern
GB9218241D0 (en) * 1992-08-27 1992-10-14 Ici Plc Chemical process

Also Published As

Publication number Publication date
CA2245547A1 (en) 1997-08-21
AR005878A1 (es) 1999-07-21
ES2162242T3 (es) 2001-12-16
CN1129573C (zh) 2003-12-03
AU709159B2 (en) 1999-08-26
PL328375A1 (en) 1999-01-18
HUP9900523A3 (en) 1999-11-29
MX9803844A (es) 1998-09-30
US6162945A (en) 2000-12-19
KR100460018B1 (ko) 2005-01-15
CA2245547C (en) 2005-07-26
CZ184498A3 (cs) 1998-09-16
NZ330387A (en) 2000-01-28
KR19990082618A (ko) 1999-11-25
IL124226A (en) 2000-10-31
DE59704450D1 (de) 2001-10-11
HU224530B1 (hu) 2005-10-28
JP2000504707A (ja) 2000-04-18
DE19605901A1 (de) 1997-08-21
WO1997030020A1 (de) 1997-08-21
EP0888280B1 (de) 2001-08-29
SK102898A3 (en) 1999-02-11
DK0888280T3 (da) 2001-10-08
BR9707444A (pt) 1999-07-20
ZA971252B (en) 1998-08-19
EP0888280A1 (de) 1999-01-07
CN1206401A (zh) 1999-01-27
ATE204850T1 (de) 2001-09-15
PL186292B1 (pl) 2003-12-31
PT888280E (pt) 2002-02-28
AU1790497A (en) 1997-09-02
GR3036530T3 (en) 2001-12-31

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HFG4 Patent granted, date of granting

Effective date: 20050908