HUP9802287A2 - Cinkkel és kívánt esetben lizinnel vagy kalciumionnal előkezelt növekedési hormont tartalmazó stabilizált gyógyszerkészítmény - Google Patents

Cinkkel és kívánt esetben lizinnel vagy kalciumionnal előkezelt növekedési hormont tartalmazó stabilizált gyógyszerkészítmény

Info

Publication number
HUP9802287A2
HUP9802287A2 HU9802287A HUP9802287A HUP9802287A2 HU P9802287 A2 HUP9802287 A2 HU P9802287A2 HU 9802287 A HU9802287 A HU 9802287A HU P9802287 A HUP9802287 A HU P9802287A HU P9802287 A2 HUP9802287 A2 HU P9802287A2
Authority
HU
Hungary
Prior art keywords
zinc
growth hormone
treated
pharmaceutical formulation
calcium ions
Prior art date
Application number
HU9802287A
Other languages
English (en)
Inventor
Per Balschmidt
Thorkild Christensen
Ole Hvilsted Olsen
Hans Holmegaard Soerensen
Lars Thim
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP9802287A2 publication Critical patent/HUP9802287A2/hu
Publication of HUP9802287A3 publication Critical patent/HUP9802287A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány tárgya gyógyszerkészítmény, amely egy cinkkel, és kívántesetben lizinnel vagy kalciűm iőnőkkal előkezelt növekedési hőrmőnttartalmaz. A találmány szerinti készítmény megnövelt stabilitású, ésgyógyászatban alkalmazható. ŕ
HU9802287A 1995-07-14 1996-06-28 A stabilized pharmaceutical formulation comprising a growth hormone pre-treated with zinc and optionally lysine or calcium ions HUP9802287A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US119395P 1995-07-14 1995-07-14

Publications (2)

Publication Number Publication Date
HUP9802287A2 true HUP9802287A2 (hu) 1999-02-01
HUP9802287A3 HUP9802287A3 (en) 2000-10-30

Family

ID=21694837

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802287A HUP9802287A3 (en) 1995-07-14 1996-06-28 A stabilized pharmaceutical formulation comprising a growth hormone pre-treated with zinc and optionally lysine or calcium ions

Country Status (14)

Country Link
EP (1) EP0839049A1 (hu)
JP (1) JPH11509212A (hu)
KR (1) KR19990028981A (hu)
CN (1) CN1190897A (hu)
AU (1) AU715997B2 (hu)
BR (1) BR9609741A (hu)
CA (1) CA2226523A1 (hu)
CZ (1) CZ9498A3 (hu)
HU (1) HUP9802287A3 (hu)
IL (1) IL122583A0 (hu)
NO (1) NO980155L (hu)
PL (1) PL324379A1 (hu)
WO (1) WO1997003692A1 (hu)
ZA (1) ZA965368B (hu)

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Also Published As

Publication number Publication date
CA2226523A1 (en) 1997-02-06
WO1997003692A1 (en) 1997-02-06
CZ9498A3 (cs) 1998-06-17
HUP9802287A3 (en) 2000-10-30
NO980155D0 (no) 1998-01-13
AU715997B2 (en) 2000-02-17
IL122583A0 (en) 1998-06-15
CN1190897A (zh) 1998-08-19
EP0839049A1 (en) 1998-05-06
NO980155L (no) 1998-01-13
JPH11509212A (ja) 1999-08-17
KR19990028981A (ko) 1999-04-15
PL324379A1 (en) 1998-05-25
MX9800358A (es) 1998-07-31
ZA965368B (en) 1997-01-14
AU6353496A (en) 1997-02-18
BR9609741A (pt) 1999-03-16

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