HUP9801117A2 - Eljárás optikailag aktív aminszármazékok előállítására - Google Patents
Eljárás optikailag aktív aminszármazékok előállításáraInfo
- Publication number
- HUP9801117A2 HUP9801117A2 HU9801117A HUP9801117A HUP9801117A2 HU P9801117 A2 HUP9801117 A2 HU P9801117A2 HU 9801117 A HU9801117 A HU 9801117A HU P9801117 A HUP9801117 A HU P9801117A HU P9801117 A2 HUP9801117 A2 HU P9801117A2
- Authority
- HU
- Hungary
- Prior art keywords
- optionally substituted
- pipe powder
- optically active
- preparing optically
- active amines
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 4
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 102000004882 Lipase Human genes 0.000 abstract 1
- 108090001060 Lipase Proteins 0.000 abstract 1
- 239000004367 Lipase Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- RWSOTUBLDIXVET-UHFFFAOYSA-M hydrosulfide Chemical compound [SH-] RWSOTUBLDIXVET-UHFFFAOYSA-M 0.000 abstract 1
- 235000019421 lipase Nutrition 0.000 abstract 1
- -1 substituted aryl bisulfite Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/86—Separation
- C07C209/88—Separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A találmány tárgya eljárás (I) általánős képletű (R)-amin-származékőkelőállítására, a képletben R1 jelentése adőtt esetben szűbsztitűált alkilcsőpőrt, R2 jelentése adőtt esetben szűbsztitűált alkilcsőpőrt, adőtt esetbenszűbsztitűált ciklőalkilcsőpőrt, adőtt esetben szűbsztitűáltciklőalkenilcsőpőrt, adőtt esetben szűbsztitűált arilcsőpőrt vagyadőtt esetben szűbsztitűált heterőciklikűs csőpőrt, ahől R1 és R2jelentése egymástól eltérő, n értéke 0, 1, 2 vagy 3, a megfelelő racém N-acil-amin-származék lipáz jelenlétében történőhidrőlizálásával. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19507217A DE19507217A1 (de) | 1995-03-02 | 1995-03-02 | Verfahren zur Herstellung von optisch aktiven Aminen |
PCT/EP1996/000835 WO1996027022A1 (de) | 1995-03-02 | 1996-03-01 | Verfahren zur herstellung von optisch aktiven aminen |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9801117A2 true HUP9801117A2 (hu) | 1998-08-28 |
HUP9801117A3 HUP9801117A3 (en) | 1998-12-28 |
HU220856B1 HU220856B1 (en) | 2002-06-29 |
Family
ID=7755407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9801117A HU220856B1 (en) | 1995-03-02 | 1996-03-01 | Process for preparing optically active amines |
Country Status (17)
Country | Link |
---|---|
US (1) | US5885787A (hu) |
EP (1) | EP0812363B1 (hu) |
JP (1) | JP3835816B2 (hu) |
KR (1) | KR100416927B1 (hu) |
CN (1) | CN1109756C (hu) |
AT (1) | ATE198911T1 (hu) |
AU (1) | AU4831596A (hu) |
BR (1) | BR9607528A (hu) |
CZ (1) | CZ291547B6 (hu) |
DE (2) | DE19507217A1 (hu) |
DK (1) | DK0812363T3 (hu) |
ES (1) | ES2154805T3 (hu) |
HU (1) | HU220856B1 (hu) |
IL (1) | IL117317A (hu) |
TW (1) | TW335392B (hu) |
WO (1) | WO1996027022A1 (hu) |
ZA (1) | ZA961676B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6678558B1 (en) * | 1999-03-25 | 2004-01-13 | Genetronics, Inc. | Method and apparatus for reducing electroporation-mediated muscle reaction and pain response |
DE102006028818A1 (de) * | 2006-06-21 | 2007-12-27 | Evonik Degussa Gmbh | Verfahren zur Herstellung enantiomerenangereicherter Amine und Amide durch enzymatische Racematspaltung |
US8221411B2 (en) * | 2008-07-28 | 2012-07-17 | Medtronic, Inc. | Systems and methods for cardiac tissue electroporation ablation |
CN102153481B (zh) * | 2011-03-07 | 2013-09-18 | 西南大学 | 氯化亚砜和醇作为n-芳基脂肪酰胺或n-杂环基脂肪酰胺选择性脱酰基反应试剂的应用 |
CN102766672A (zh) * | 2011-05-06 | 2012-11-07 | 王际宽 | 一种手性胺的动力学拆分方法 |
CN108658784B (zh) * | 2018-04-26 | 2020-12-18 | 联化科技股份有限公司 | (r)-1-(4-甲基苯基)乙胺的合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2698627B2 (ja) * | 1988-10-11 | 1998-01-19 | ダイセル化学工業株式会社 | 光学活性アミン及びその誘導体の製造方法 |
GB8911456D0 (en) * | 1989-05-18 | 1989-07-05 | Earl & Wright Ltd | Locating arrangement |
-
1995
- 1995-03-02 DE DE19507217A patent/DE19507217A1/de not_active Withdrawn
-
1996
- 1996-02-29 IL IL11731796A patent/IL117317A/xx not_active IP Right Cessation
- 1996-03-01 ZA ZA961676A patent/ZA961676B/xx unknown
- 1996-03-01 AT AT96904087T patent/ATE198911T1/de not_active IP Right Cessation
- 1996-03-01 ES ES96904087T patent/ES2154805T3/es not_active Expired - Lifetime
- 1996-03-01 KR KR1019970706032A patent/KR100416927B1/ko not_active IP Right Cessation
- 1996-03-01 DE DE59606386T patent/DE59606386D1/de not_active Expired - Fee Related
- 1996-03-01 JP JP52602496A patent/JP3835816B2/ja not_active Expired - Fee Related
- 1996-03-01 HU HU9801117A patent/HU220856B1/hu not_active IP Right Cessation
- 1996-03-01 AU AU48315/96A patent/AU4831596A/en not_active Abandoned
- 1996-03-01 BR BR9607528A patent/BR9607528A/pt not_active IP Right Cessation
- 1996-03-01 US US08/894,668 patent/US5885787A/en not_active Expired - Fee Related
- 1996-03-01 WO PCT/EP1996/000835 patent/WO1996027022A1/de active IP Right Grant
- 1996-03-01 EP EP96904087A patent/EP0812363B1/de not_active Expired - Lifetime
- 1996-03-01 DK DK96904087T patent/DK0812363T3/da active
- 1996-03-01 CN CN96192310A patent/CN1109756C/zh not_active Expired - Fee Related
- 1996-03-01 CZ CZ19972755A patent/CZ291547B6/cs not_active IP Right Cessation
- 1996-03-02 TW TW085102644A patent/TW335392B/zh active
Also Published As
Publication number | Publication date |
---|---|
TW335392B (en) | 1998-07-01 |
IL117317A (en) | 2000-01-31 |
CN1177382A (zh) | 1998-03-25 |
CZ275597A3 (en) | 1997-11-12 |
US5885787A (en) | 1999-03-23 |
ES2154805T3 (es) | 2001-04-16 |
JPH11500911A (ja) | 1999-01-26 |
CN1109756C (zh) | 2003-05-28 |
KR19980702627A (ko) | 1998-08-05 |
ZA961676B (en) | 1996-09-05 |
IL117317A0 (en) | 1996-06-18 |
EP0812363B1 (de) | 2001-01-24 |
DE59606386D1 (de) | 2001-03-01 |
KR100416927B1 (ko) | 2004-05-24 |
CZ291547B6 (cs) | 2003-04-16 |
AU4831596A (en) | 1996-09-18 |
WO1996027022A1 (de) | 1996-09-06 |
ATE198911T1 (de) | 2001-02-15 |
BR9607528A (pt) | 1997-12-30 |
HU220856B1 (en) | 2002-06-29 |
EP0812363A1 (de) | 1997-12-17 |
DK0812363T3 (da) | 2001-04-09 |
MX9706609A (es) | 1997-11-29 |
HUP9801117A3 (en) | 1998-12-28 |
DE19507217A1 (de) | 1996-09-05 |
JP3835816B2 (ja) | 2006-10-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |