HUP9700358A3 - New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP9700358A3
HUP9700358A3 HU9700358A HUP9700358A HUP9700358A3 HU P9700358 A3 HUP9700358 A3 HU P9700358A3 HU 9700358 A HU9700358 A HU 9700358A HU P9700358 A HUP9700358 A HU P9700358A HU P9700358 A3 HUP9700358 A3 HU P9700358A3
Authority
HU
Hungary
Prior art keywords
oxazolidinon
derivatives
preparation
new
pharmaceutical compositions
Prior art date
Application number
HU9700358A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HU9700358D0 publication Critical patent/HU9700358D0/hu
Publication of HUP9700358A2 publication Critical patent/HUP9700358A2/hu
Publication of HUP9700358A3 publication Critical patent/HUP9700358A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/4211,3-Oxazoles, e.g. pemoline, trimethadione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65844Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a five-membered ring which may be condensed with another ring system
HU9700358A 1996-02-06 1997-02-05 New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them HUP9700358A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19604223A DE19604223A1 (de) 1996-02-06 1996-02-06 Neue substituierte Oxazolidinone

Publications (3)

Publication Number Publication Date
HU9700358D0 HU9700358D0 (en) 1997-03-28
HUP9700358A2 HUP9700358A2 (hu) 1998-07-28
HUP9700358A3 true HUP9700358A3 (en) 1999-08-30

Family

ID=7784633

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9700358A HUP9700358A3 (en) 1996-02-06 1997-02-05 New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (36)

Country Link
US (1) US5792765A (hu)
EP (1) EP0789025B1 (hu)
JP (1) JPH09316073A (hu)
KR (1) KR970061888A (hu)
CN (1) CN1160051A (hu)
AR (1) AR005703A1 (hu)
AT (1) ATE200285T1 (hu)
AU (1) AU1251697A (hu)
BG (1) BG101193A (hu)
BR (1) BR9700885A (hu)
CA (1) CA2196862A1 (hu)
CO (1) CO4560411A1 (hu)
CZ (1) CZ34097A3 (hu)
DE (2) DE19604223A1 (hu)
DK (1) DK0789025T3 (hu)
EE (1) EE9700043A (hu)
ES (1) ES2157027T3 (hu)
GR (1) GR3036015T3 (hu)
HR (1) HRP970048A2 (hu)
HU (1) HUP9700358A3 (hu)
ID (1) ID15881A (hu)
IL (1) IL120125A0 (hu)
MX (1) MX9700886A (hu)
NO (1) NO970511L (hu)
NZ (1) NZ314179A (hu)
PL (1) PL318277A1 (hu)
PT (1) PT789025E (hu)
SG (1) SG50791A1 (hu)
SI (1) SI0789025T1 (hu)
SK (1) SK15897A3 (hu)
SV (1) SV1997000009A (hu)
TN (1) TNSN97032A1 (hu)
TR (1) TR199700092A2 (hu)
TW (1) TW350845B (hu)
YU (1) YU4397A (hu)
ZA (1) ZA97927B (hu)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
WO1998054161A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
AU9001598A (en) * 1997-09-11 1999-03-29 Hokuriku Seiyaku Co. Ltd Thiourea derivatives
EP1028940B1 (en) * 1997-11-07 2007-04-18 Pharmacia & Upjohn Company LLC Process to produce oxazolidinones
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
CA2318969A1 (en) * 1998-01-23 1999-07-29 Mikhail F. Gordeev Oxazolidinone combinatorial libraries, compositions and methods of preparation
HUP0103082A3 (en) * 1998-06-05 2002-12-28 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) * 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
JP2000204084A (ja) * 1998-11-11 2000-07-25 Hokuriku Seiyaku Co Ltd チオカルバミド酸誘導体
AU1045300A (en) * 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel heterocyclyl-substituted oxazolidone derivatives
AU1379900A (en) * 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel substituted phenyloxazolidone derivatives
US6403804B1 (en) 1998-12-07 2002-06-11 Takasago International Corporation Process for preparing optically active oxazolidinone derivative
CN1142162C (zh) 1999-05-27 2004-03-17 法玛西雅厄普约翰美国公司 作为抗菌剂的新的双环噁唑烷酮
MXPA02000985A (es) * 1999-07-28 2002-07-30 Upjohn Co Oxazolidinonas y su uso como antiinfecciosos.
US6608081B2 (en) * 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6413981B1 (en) 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6297242B1 (en) 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
DK1111583T3 (da) 1999-12-23 2003-09-22 Hans-Peter Wilfer Kasse til musikinstrumenter, især guitarer
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
KR100355345B1 (ko) * 2000-01-21 2002-10-12 한국과학기술연구원 티오펜환을 함유한 신규한 옥사졸리디논 유도체, 그의 제조방법 및 조성물
MY127336A (en) * 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
PE20011124A1 (es) 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
AU2001272961A1 (en) 2000-06-30 2002-01-14 Pharmacia & Upjohn Company Compositions for treating bacterial infections containing oxazolidinone compound, sulbactam and an ampicillin
PE20030044A1 (es) * 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
AU2002256995A1 (en) * 2001-02-07 2002-08-28 Ortho-Mcneil Pharmaceutical, Inc. Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods
DE10129725A1 (de) * 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
WO2003084534A1 (en) * 2002-03-29 2003-10-16 Pharmacia & Upjohn Company Llc Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
WO2004026848A1 (en) * 2002-09-20 2004-04-01 Lupin Limited Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
ES2271660T3 (es) * 2002-11-21 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de n-(4-piperazin-1-il)-fenil-2-oxazolidinona-5-carboxamida y compuestos relacionados como agentes antibacterianos.
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
BRPI0407304A (pt) * 2003-02-07 2006-01-10 Warner Lambert Co Agentes antibacterianos
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
BRPI0413838A (pt) * 2003-08-25 2006-10-24 Warner Lambert Co compostos de ariloxazolidinona antimicrobianos
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
WO2005082897A1 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
EP1934237A2 (en) 2005-08-24 2008-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
EP1928893A2 (en) 2005-08-24 2008-06-11 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
EP1934208B1 (de) 2005-10-04 2011-03-23 Bayer Schering Pharma Aktiengesellschaft Neue polymorphe form von 5-chlor-n-({ ( 5s )-2-0x0-3-[4-( 3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl} -methyl)-2-thiophencarboxamid
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
WO2008021309A1 (en) * 2006-08-15 2008-02-21 Wyeth Imidazolidin-2-one derivatives useful as pr modulators
US7649007B2 (en) * 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
TW200815428A (en) 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
US7538107B2 (en) 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
DE102006051625A1 (de) * 2006-11-02 2008-05-08 Bayer Materialscience Ag Kombinationstherapie substituierter Oxazolidinone
WO2008143649A2 (en) * 2006-12-04 2008-11-27 Dr. Reddy's Laboratories Limited Novel oxazolidinone compounds as antiinfective agents
PL2254887T3 (pl) 2008-02-22 2013-05-31 Actelion Pharmaceuticals Ltd Pochodne oksazolidynonu
WO2018170664A1 (en) * 2017-03-20 2018-09-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705799A (en) 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4965268A (en) * 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) * 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4942183A (en) * 1987-10-16 1990-07-17 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
CA1320730C (en) 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US5254577A (en) 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
DE68929303T2 (de) 1988-09-15 2002-05-02 Upjohn Co 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
JP2669579B2 (ja) * 1991-10-23 1997-10-29 エーザイ株式会社 オキサゾリドン誘導体
DE4303303C1 (de) 1993-02-05 1994-02-17 Freudenberg Carl Fa Antriebsstrang eines Kraftfahrzeugs
DE4332384A1 (de) 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
TW286317B (hu) 1993-12-13 1996-09-21 Hoffmann La Roche
DE4425613A1 (de) 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425609A1 (de) 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
HRP960159A2 (en) 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms

Also Published As

Publication number Publication date
AR005703A1 (es) 1999-07-14
CO4560411A1 (es) 1998-02-10
EP0789025A1 (de) 1997-08-13
CZ34097A3 (en) 1997-08-13
DK0789025T3 (da) 2001-06-18
DE19604223A1 (de) 1997-08-07
HU9700358D0 (en) 1997-03-28
GR3036015T3 (en) 2001-09-28
ZA97927B (en) 1997-08-19
NO970511D0 (no) 1997-02-05
AU1251697A (en) 1997-08-14
TR199700092A2 (tr) 1997-08-21
YU4397A (sh) 1999-09-27
EE9700043A (et) 1997-08-15
SI0789025T1 (en) 2001-08-31
JPH09316073A (ja) 1997-12-09
SK15897A3 (en) 1997-10-08
DE59703261D1 (de) 2001-05-10
US5792765A (en) 1998-08-11
EP0789025B1 (de) 2001-04-04
HRP970048A2 (en) 1998-04-30
IL120125A0 (en) 1997-06-10
ID15881A (id) 1997-08-14
KR970061888A (ko) 1997-09-12
SG50791A1 (en) 1998-07-20
PL318277A1 (en) 1997-08-18
HUP9700358A2 (hu) 1998-07-28
TNSN97032A1 (fr) 2005-03-15
ES2157027T3 (es) 2001-08-01
MX9700886A (es) 1998-04-30
NZ314179A (en) 1998-12-23
CA2196862A1 (en) 1997-08-07
SV1997000009A (es) 1997-10-23
TW350845B (en) 1999-01-21
BR9700885A (pt) 1998-10-27
BG101193A (en) 1999-02-26
PT789025E (pt) 2001-07-31
NO970511L (no) 1997-08-07
CN1160051A (zh) 1997-09-24
ATE200285T1 (de) 2001-04-15

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