HUP0400818A2 - Tieno[2,3-d]pirimidinek alkalmazása és az ezeket tartalmazó gyógyszerkészítmények - Google Patents
Tieno[2,3-d]pirimidinek alkalmazása és az ezeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0400818A2 HUP0400818A2 HU0400818A HUP0400818A HUP0400818A2 HU P0400818 A2 HUP0400818 A2 HU P0400818A2 HU 0400818 A HU0400818 A HU 0400818A HU P0400818 A HUP0400818 A HU P0400818A HU P0400818 A2 HUP0400818 A2 HU P0400818A2
- Authority
- HU
- Hungary
- Prior art keywords
- hal
- alkylene group
- hydrogen
- thieno
- pyrimidines
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- DDWBRNXDKNIQDY-UHFFFAOYSA-N thieno[2,3-d]pyrimidine Chemical class N1=CN=C2SC=CC2=C1 DDWBRNXDKNIQDY-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- -1 COOA Chemical group 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000018262 Peripheral vascular disease Diseases 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000009961 allergic asthma Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 208000023819 chronic asthma Diseases 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000012201 sexual and gender identity disease Diseases 0.000 abstract 1
- 208000015891 sexual disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Gynecology & Obstetrics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány tárgya az (I) általános képletű tieno (2,3-d) pirimidinekés fiziológiailag elfogadható sói ahol R1 és R2 jelentése egymástólfüggetlenül hidrogénatom, A vagy Hal, ahol R1 vagy R2 közül az egyikcsoport mindig hidrogéntől eltérő; R1 és R2 együtt 3-5 szénatomosalkiléncsoportot is képezhet; R3 és R4 egymástól függetlenül lehethidrogénatom, A, OA, hidroxilcsoport vagy Hal; R3 és R4 együtt 3-5szénatomos alkilén-, -O-CH2-CH2-, -O-CH2-O vagy O-CH2-CH2-O- csoportotis képezhet; X jelentése R5 vagy R6, amely R7-tel mono-szubsztituált;R5 jelentése egyenes vagy elágazó láncú 1-10 szénatomosalkiléncsoport, amelyben egy vagy két metiléncsoportot -CH=CH- csoporthelyettesíthet, vagy -C6H4-(CH2)m-; R6 jelentése 6-12 szénatomoscikloalkil-alkilén-csoport, R7 jelentése COOH, COOA, CONH2, CONHA,CON(A)2 vagy cianocsoport; A jelentése 1-6 szénatomos alkilcsoport;Hal jelentése fluor-, klór-, bróm- vagy jódatom; m értéke 1 vagy 2; ésn értéke 0, 1 , 2 vagy 3 alkalmazása gyógyszer előállítására, amelyangina, magas vérnyomás, magas tüdőnyomás, tolulásos szívelégtelenség,ateroszklerózis, szíverek csökkent átjárhatóságú állapota, perifériásérbetegség, stroke, bronchitis, allergiás asztma, krónikus asztma,allergiás nátha, glaukóma, irritációs bélszindróma, tumor,veseelégtelen ség, májzsugor és női szexuális rendellenességekkezelésére. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10058663A DE10058663A1 (de) | 2000-11-25 | 2000-11-25 | Verwendung von Thienopyrimidinen |
PCT/EP2001/012494 WO2002041896A2 (de) | 2000-11-25 | 2001-10-29 | Verwendung von thienopyrimidinen |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0400818A2 true HUP0400818A2 (hu) | 2004-07-28 |
Family
ID=7664711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0400818A HUP0400818A2 (hu) | 2000-11-25 | 2001-10-29 | Tieno[2,3-d]pirimidinek alkalmazása és az ezeket tartalmazó gyógyszerkészítmények |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040034040A1 (hu) |
EP (1) | EP1337256A2 (hu) |
JP (1) | JP2004513966A (hu) |
KR (1) | KR20030051867A (hu) |
CN (1) | CN1474693A (hu) |
AR (1) | AR032482A1 (hu) |
AU (1) | AU2002224808A1 (hu) |
BR (1) | BR0115247A (hu) |
CA (1) | CA2429647A1 (hu) |
CZ (1) | CZ20031618A3 (hu) |
DE (1) | DE10058663A1 (hu) |
HU (1) | HUP0400818A2 (hu) |
MX (1) | MXPA03004582A (hu) |
PL (1) | PL361277A1 (hu) |
RU (1) | RU2003117478A (hu) |
SK (1) | SK7352003A3 (hu) |
WO (1) | WO2002041896A2 (hu) |
ZA (1) | ZA200304909B (hu) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60336576D1 (de) * | 2002-10-30 | 2011-05-12 | Merck Sharp & Dohme | Hemmer der akt aktivität |
ES2280040T3 (es) * | 2003-07-24 | 2007-09-01 | Bayer Pharmaceuticals Corporation | Compuestos de tetrahidrobenzotienopirimidinamina sustituidos utiles para tratar trastornos hiperproliferativos. |
TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | 1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途 |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
CN101801951B (zh) | 2007-09-14 | 2013-11-13 | 杨森制药有限公司 | 1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮 |
EP2200985B1 (en) | 2007-09-14 | 2011-07-13 | Ortho-McNeil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones |
AU2008297877C1 (en) | 2007-09-14 | 2013-11-07 | Addex Pharma S.A. | 1,3-disubstituted-4-phenyl-1 H-pyridin-2-ones |
CN101861316B (zh) | 2007-11-14 | 2013-08-21 | 奥梅-杨森制药有限公司 | 咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
JP5656848B2 (ja) | 2008-10-16 | 2015-01-21 | ジャンセン ファーマシューティカルズ, インコーポレイテッド. | 代謝型グルタミン酸受容体モジュレーターとしてのインドールおよびベンゾモルホリンの誘導体 |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
MX2011011962A (es) | 2009-05-12 | 2012-02-28 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostericos positivos de receptores de glutamato metabotropico (mglur2). |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
ME01573B (me) | 2009-05-12 | 2014-09-20 | Addex Pharma Sa | DERIVATI 1,2,4-TRIAZOLO[4,3-a]PIRIDINA I NJIHOVA UPOTREBA U TRETMANU ILI PREVENCIJI NEUROLOŠKIH I PSIHIJATRIJSKIH POREMEĆAJA |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
AU2011328195B2 (en) | 2010-11-08 | 2015-04-02 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
JP5852666B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
CN103946226A (zh) | 2011-07-19 | 2014-07-23 | 无限药品股份有限公司 | 杂环化合物及其应用 |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
KR20200036063A (ko) | 2014-01-21 | 2020-04-06 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
PL3096790T3 (pl) | 2014-01-21 | 2020-01-31 | Janssen Pharmaceutica, N.V. | Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie |
FR3037956B1 (fr) * | 2015-06-23 | 2017-08-04 | Servier Lab | Nouveaux derives d'acide amine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
WO1998015530A1 (fr) * | 1996-10-08 | 1998-04-16 | Fujisawa Pharmaceutical Co., Ltd. | Derives d'indol |
DE19752952A1 (de) * | 1997-11-28 | 1999-06-02 | Merck Patent Gmbh | Thienopyrimidine |
NZ504958A (en) * | 1997-12-12 | 2003-03-28 | Cell Pathways Inc | N-benzyl-3-indenylacetamides derivatives for treating neoplasia |
AU748352B2 (en) * | 1998-04-20 | 2002-06-06 | Pfizer Inc. | Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction |
US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
DE19919828A1 (de) * | 1999-04-30 | 2000-11-02 | Aventis Pharma Gmbh | Verwendung von Xanthinderivaten zur Behandlung von Erektionsstörungen |
CA2339630C (en) * | 1998-09-16 | 2006-05-23 | Icos Corporation | Carboline derivatives as cgmp phosphodiesterase inhibitors |
US6133271A (en) * | 1998-11-19 | 2000-10-17 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives |
FR2792635B1 (fr) * | 1999-04-20 | 2001-06-01 | Synthelabo | Derives de cyclobutene-3,4-dione leur preparation et leur application en therapeutique |
DE10042997A1 (de) * | 2000-09-01 | 2002-03-14 | Merck Patent Gmbh | Thienopyrimidine |
-
2000
- 2000-11-25 DE DE10058663A patent/DE10058663A1/de not_active Withdrawn
-
2001
- 2001-10-29 EP EP01994626A patent/EP1337256A2/de not_active Withdrawn
- 2001-10-29 CZ CZ20031618A patent/CZ20031618A3/cs unknown
- 2001-10-29 MX MXPA03004582A patent/MXPA03004582A/es unknown
- 2001-10-29 HU HU0400818A patent/HUP0400818A2/hu unknown
- 2001-10-29 BR BR0115247-5A patent/BR0115247A/pt not_active Application Discontinuation
- 2001-10-29 JP JP2002544074A patent/JP2004513966A/ja active Pending
- 2001-10-29 KR KR10-2003-7006921A patent/KR20030051867A/ko not_active Application Discontinuation
- 2001-10-29 PL PL01361277A patent/PL361277A1/xx unknown
- 2001-10-29 CN CNA018191800A patent/CN1474693A/zh active Pending
- 2001-10-29 SK SK735-2003A patent/SK7352003A3/sk unknown
- 2001-10-29 WO PCT/EP2001/012494 patent/WO2002041896A2/de not_active Application Discontinuation
- 2001-10-29 AU AU2002224808A patent/AU2002224808A1/en not_active Abandoned
- 2001-10-29 US US10/432,778 patent/US20040034040A1/en not_active Abandoned
- 2001-10-29 RU RU2003117478/15A patent/RU2003117478A/ru not_active Application Discontinuation
- 2001-10-29 CA CA002429647A patent/CA2429647A1/en not_active Abandoned
- 2001-11-23 AR ARP010105462A patent/AR032482A1/es unknown
-
2003
- 2003-06-24 ZA ZA200304909A patent/ZA200304909B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20030051867A (ko) | 2003-06-25 |
EP1337256A2 (de) | 2003-08-27 |
MXPA03004582A (es) | 2003-09-04 |
PL361277A1 (en) | 2004-10-04 |
RU2003117478A (ru) | 2004-11-27 |
CA2429647A1 (en) | 2002-05-30 |
CN1474693A (zh) | 2004-02-11 |
ZA200304909B (en) | 2004-08-25 |
SK7352003A3 (en) | 2003-11-04 |
BR0115247A (pt) | 2003-08-12 |
AU2002224808A1 (en) | 2002-06-03 |
AR032482A1 (es) | 2003-11-12 |
WO2002041896A2 (de) | 2002-05-30 |
CZ20031618A3 (cs) | 2003-10-15 |
JP2004513966A (ja) | 2004-05-13 |
WO2002041896A3 (de) | 2002-10-31 |
DE10058663A1 (de) | 2002-05-29 |
US20040034040A1 (en) | 2004-02-19 |
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