HUP0400189A3 - Method for preparation of mycophenolate mofetil - Google Patents

Method for preparation of mycophenolate mofetil

Info

Publication number
HUP0400189A3
HUP0400189A3 HU0400189A HUP0400189A HUP0400189A3 HU P0400189 A3 HUP0400189 A3 HU P0400189A3 HU 0400189 A HU0400189 A HU 0400189A HU P0400189 A HUP0400189 A HU P0400189A HU P0400189 A3 HUP0400189 A3 HU P0400189A3
Authority
HU
Hungary
Prior art keywords
preparation
mycophenolate mofetil
mofetil
mycophenolate
Prior art date
Application number
HU0400189A
Other languages
English (en)
Original Assignee
Ivax Pharmaceuticals Sro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Pharmaceuticals Sro filed Critical Ivax Pharmaceuticals Sro
Publication of HUP0400189A2 publication Critical patent/HUP0400189A2/hu
Publication of HUP0400189A3 publication Critical patent/HUP0400189A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
HU0400189A 2001-06-08 2002-06-08 Method for preparation of mycophenolate mofetil HUP0400189A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20012071A CZ292123B6 (cs) 2001-06-08 2001-06-08 Způsob přípravy mykofenolátu mofetilu
PCT/US2002/018274 WO2002100855A1 (en) 2001-06-08 2002-06-08 Method of mycophenolate mofetil preparation

Publications (2)

Publication Number Publication Date
HUP0400189A2 HUP0400189A2 (hu) 2004-07-28
HUP0400189A3 true HUP0400189A3 (en) 2007-05-29

Family

ID=5473426

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0400189A HUP0400189A3 (en) 2001-06-08 2002-06-08 Method for preparation of mycophenolate mofetil

Country Status (17)

Country Link
US (1) US20050085635A1 (hu)
EP (1) EP1421081A4 (hu)
JP (1) JP2004534063A (hu)
KR (1) KR20040030660A (hu)
CN (1) CN1253450C (hu)
AR (1) AR041777A1 (hu)
BR (1) BR0210931A (hu)
CA (1) CA2450013A1 (hu)
CZ (1) CZ292123B6 (hu)
HK (1) HK1068630A1 (hu)
HU (1) HUP0400189A3 (hu)
NZ (1) NZ530013A (hu)
PL (1) PL364366A1 (hu)
RU (1) RU2283313C2 (hu)
SK (1) SK285663B6 (hu)
TW (1) TWI241299B (hu)
WO (1) WO2002100855A1 (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2537958C (en) * 2003-09-11 2013-06-11 Sandoz Ag Process for the production of mycophenolate mofetil
JP2007532585A (ja) 2004-04-26 2007-11-15 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ ミコフェノール酸及びそのエステル誘導体の調製方法
WO2005105769A2 (en) 2004-04-27 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg - Mycophenolate mofetil impurity
ES2340184T3 (es) 2004-07-20 2010-05-31 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Micofenolato sodico cristalino.
ITMI20041703A1 (it) * 2004-09-03 2004-12-03 Poli Ind Chimica Spa Metodo di preparazione del mofetil micofenolato per transesterificazione enzimatica
CN1328272C (zh) * 2005-08-22 2007-07-25 鲁南制药集团股份有限公司 一种工业化生产霉酚酸莫啡酯的方法
CN100402516C (zh) * 2005-10-18 2008-07-16 深圳市东阳光实业发展有限公司 一种霉酚酸莫啡酯的制备方法
WO2008002665A1 (en) * 2006-06-29 2008-01-03 Teva Pharmaceutical Industries Ltd. Regulation of acid metabolite production
CN1974564B (zh) * 2006-12-15 2010-05-12 丽珠集团新北江制药股份有限公司 一种霉酚酸莫啡酯的制备方法
US20080188653A1 (en) 2007-02-04 2008-08-07 Formosa Laboratories, Inc. Process for Preparation of Mycophenolate Mofetil
CN100484930C (zh) * 2007-03-16 2009-05-06 重庆大新药业股份有限公司 一种吗替麦考酚酯的制备方法
US20080254520A1 (en) * 2007-04-11 2008-10-16 Eva Gulyas Method for reducing impurity level in mycophenolic acid fermentation
WO2009000834A1 (en) * 2007-06-27 2008-12-31 Dsm Ip Assets B.V. Method for the purification of mycophenolate mofetil
WO2009003878A1 (en) * 2007-06-29 2009-01-08 Dsm Ip Assets B.V. Method for the preparation of mycophenolate mofetil
WO2009010503A1 (en) * 2007-07-18 2009-01-22 Dsm Ip Assets B.V. Mycophenolic acid recycling in a method for the preparation of mycophenolate mofetil
CN101671706B (zh) * 2009-09-05 2013-09-18 山东新时代药业有限公司 一种霉酚酸发酵过程中补糖方法
CN103265514B (zh) * 2013-06-08 2016-01-13 重庆理工大学 一种制备吗替麦考酚酯的方法
CN107056736A (zh) * 2017-05-08 2017-08-18 福建省微生物研究所 一种吗替麦考酚酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748173A (en) * 1987-01-30 1988-05-31 Syntex (U.S.A.) Inc. Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions
HU203678B (en) * 1988-09-26 1991-09-30 Richter Gedeon Vegyeszet Method for increased dewatering condensation reaction mixtures
US5247083A (en) * 1992-07-10 1993-09-21 Syntex (U.S.A.) Inc. Direct esterification of mycophenolic acid

Also Published As

Publication number Publication date
EP1421081A4 (en) 2004-11-03
CZ20012071A3 (cs) 2003-01-15
SK285663B6 (sk) 2007-05-03
JP2004534063A (ja) 2004-11-11
EP1421081A1 (en) 2004-05-26
SK15062003A3 (en) 2004-11-03
CZ292123B6 (cs) 2003-08-13
CA2450013A1 (en) 2002-12-19
WO2002100855A1 (en) 2002-12-19
PL364366A1 (en) 2004-12-13
BR0210931A (pt) 2004-06-08
TWI241299B (en) 2005-10-11
AR041777A1 (es) 2005-06-01
CN1253450C (zh) 2006-04-26
HUP0400189A2 (hu) 2004-07-28
RU2004100227A (ru) 2005-06-27
NZ530013A (en) 2005-05-27
KR20040030660A (ko) 2004-04-09
US20050085635A1 (en) 2005-04-21
RU2283313C2 (ru) 2006-09-10
CN1520411A (zh) 2004-08-11
HK1068630A1 (en) 2005-04-29

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Legal Events

Date Code Title Description
FH91 Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): RAVADITS IMRE, DANUBIA SZABADALMI ES VEDJEGY IRODA KFT., HU

Representative=s name: IFJ. SZENTPETERI ADAM, S.B.G. & K. SZABADALMI , HU

FH92 Termination of representative

Representative=s name: RAVADITS IMRE, DANUBIA SZABADALMI ES VEDJEGY I, HU