CZ20012071A3 - Způsob přípravy mykofenolátu mofetilu - Google Patents

Způsob přípravy mykofenolátu mofetilu

Info

Publication number
CZ20012071A3
CZ20012071A3 CZ20012071A CZ20012071A CZ20012071A3 CZ 20012071 A3 CZ20012071 A3 CZ 20012071A3 CZ 20012071 A CZ20012071 A CZ 20012071A CZ 20012071 A CZ20012071 A CZ 20012071A CZ 20012071 A3 CZ20012071 A3 CZ 20012071A3
Authority
CZ
Czechia
Prior art keywords
preparing
mofetil mycophenolate
mofetil
mycophenolate
preparing mofetil
Prior art date
Application number
CZ20012071A
Other languages
English (en)
Other versions
CZ292123B6 (cs
Inventor
Miloslav Ing. Chudík Phd
Ale© Rndr. Csc. Husek
Original Assignee
Ivax-Cr A. S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax-Cr A. S. filed Critical Ivax-Cr A. S.
Priority to CZ20012071A priority Critical patent/CZ292123B6/cs
Priority to TW091112451A priority patent/TWI241299B/zh
Priority to ARP020102144A priority patent/AR041777A1/es
Priority to CNB028126998A priority patent/CN1253450C/zh
Priority to JP2003503622A priority patent/JP2004534063A/ja
Priority to EP02756146A priority patent/EP1421081A4/en
Priority to BR0210931-0A priority patent/BR0210931A/pt
Priority to RU2004100227/04A priority patent/RU2283313C2/ru
Priority to HU0400189A priority patent/HUP0400189A3/hu
Priority to NZ530013A priority patent/NZ530013A/en
Priority to PL02364366A priority patent/PL364366A1/xx
Priority to CA002450013A priority patent/CA2450013A1/en
Priority to KR10-2003-7016069A priority patent/KR20040030660A/ko
Priority to US10/480,058 priority patent/US20050085635A1/en
Priority to SK1506-2003A priority patent/SK285663B6/sk
Priority to PCT/US2002/018274 priority patent/WO2002100855A1/en
Publication of CZ20012071A3 publication Critical patent/CZ20012071A3/cs
Publication of CZ292123B6 publication Critical patent/CZ292123B6/cs
Priority to HK05101061A priority patent/HK1068630A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
CZ20012071A 2001-06-08 2001-06-08 Způsob přípravy mykofenolátu mofetilu CZ292123B6 (cs)

Priority Applications (17)

Application Number Priority Date Filing Date Title
CZ20012071A CZ292123B6 (cs) 2001-06-08 2001-06-08 Způsob přípravy mykofenolátu mofetilu
TW091112451A TWI241299B (en) 2001-06-08 2002-06-07 Method of mycophenolate mofetil preparation
ARP020102144A AR041777A1 (es) 2001-06-08 2002-06-07 Proceso de preparacion de micofenolato mofetilo
NZ530013A NZ530013A (en) 2001-06-08 2002-06-08 Process for the preparation of mycophenolate mofetil
PL02364366A PL364366A1 (en) 2001-06-08 2002-06-08 Method of mycophenolate mofetil preparation
EP02756146A EP1421081A4 (en) 2001-06-08 2002-06-08 METHOD FOR PRODUCING MYCOPHENOLATE MOFETIL
BR0210931-0A BR0210931A (pt) 2001-06-08 2002-06-08 Processo de preparação de micofenolato de mofetila
RU2004100227/04A RU2283313C2 (ru) 2001-06-08 2002-06-08 Способ получения микофенолят мофетила
HU0400189A HUP0400189A3 (en) 2001-06-08 2002-06-08 Method for preparation of mycophenolate mofetil
CNB028126998A CN1253450C (zh) 2001-06-08 2002-06-08 霉酚酸莫啡酯的制备方法
JP2003503622A JP2004534063A (ja) 2001-06-08 2002-06-08 ミコフェノール酸モフェチルの調製法
CA002450013A CA2450013A1 (en) 2001-06-08 2002-06-08 Method of mycophenolate mofetil preparation
KR10-2003-7016069A KR20040030660A (ko) 2001-06-08 2002-06-08 마이코페놀레이트 모페틸의 제조방법
US10/480,058 US20050085635A1 (en) 2001-06-08 2002-06-08 Method of mycophenolate mofetil preparation
SK1506-2003A SK285663B6 (sk) 2001-06-08 2002-06-08 Spôsob prípravy mykofenolátu mofetilu
PCT/US2002/018274 WO2002100855A1 (en) 2001-06-08 2002-06-08 Method of mycophenolate mofetil preparation
HK05101061A HK1068630A1 (en) 2001-06-08 2005-02-18 Method of mycophenolate mofetil preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ20012071A CZ292123B6 (cs) 2001-06-08 2001-06-08 Způsob přípravy mykofenolátu mofetilu

Publications (2)

Publication Number Publication Date
CZ20012071A3 true CZ20012071A3 (cs) 2003-01-15
CZ292123B6 CZ292123B6 (cs) 2003-08-13

Family

ID=5473426

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20012071A CZ292123B6 (cs) 2001-06-08 2001-06-08 Způsob přípravy mykofenolátu mofetilu

Country Status (17)

Country Link
US (1) US20050085635A1 (cs)
EP (1) EP1421081A4 (cs)
JP (1) JP2004534063A (cs)
KR (1) KR20040030660A (cs)
CN (1) CN1253450C (cs)
AR (1) AR041777A1 (cs)
BR (1) BR0210931A (cs)
CA (1) CA2450013A1 (cs)
CZ (1) CZ292123B6 (cs)
HK (1) HK1068630A1 (cs)
HU (1) HUP0400189A3 (cs)
NZ (1) NZ530013A (cs)
PL (1) PL364366A1 (cs)
RU (1) RU2283313C2 (cs)
SK (1) SK285663B6 (cs)
TW (1) TWI241299B (cs)
WO (1) WO2002100855A1 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2537958C (en) * 2003-09-11 2013-06-11 Sandoz Ag Process for the production of mycophenolate mofetil
JP2007532585A (ja) 2004-04-26 2007-11-15 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ ミコフェノール酸及びそのエステル誘導体の調製方法
WO2005105769A2 (en) 2004-04-27 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg - Mycophenolate mofetil impurity
ES2340184T3 (es) 2004-07-20 2010-05-31 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Micofenolato sodico cristalino.
ITMI20041703A1 (it) * 2004-09-03 2004-12-03 Poli Ind Chimica Spa Metodo di preparazione del mofetil micofenolato per transesterificazione enzimatica
CN1328272C (zh) * 2005-08-22 2007-07-25 鲁南制药集团股份有限公司 一种工业化生产霉酚酸莫啡酯的方法
CN100402516C (zh) * 2005-10-18 2008-07-16 深圳市东阳光实业发展有限公司 一种霉酚酸莫啡酯的制备方法
WO2008002665A1 (en) * 2006-06-29 2008-01-03 Teva Pharmaceutical Industries Ltd. Regulation of acid metabolite production
CN1974564B (zh) * 2006-12-15 2010-05-12 丽珠集团新北江制药股份有限公司 一种霉酚酸莫啡酯的制备方法
US20080188653A1 (en) 2007-02-04 2008-08-07 Formosa Laboratories, Inc. Process for Preparation of Mycophenolate Mofetil
CN100484930C (zh) * 2007-03-16 2009-05-06 重庆大新药业股份有限公司 一种吗替麦考酚酯的制备方法
US20080254520A1 (en) * 2007-04-11 2008-10-16 Eva Gulyas Method for reducing impurity level in mycophenolic acid fermentation
WO2009000834A1 (en) * 2007-06-27 2008-12-31 Dsm Ip Assets B.V. Method for the purification of mycophenolate mofetil
WO2009003878A1 (en) * 2007-06-29 2009-01-08 Dsm Ip Assets B.V. Method for the preparation of mycophenolate mofetil
WO2009010503A1 (en) * 2007-07-18 2009-01-22 Dsm Ip Assets B.V. Mycophenolic acid recycling in a method for the preparation of mycophenolate mofetil
CN101671706B (zh) * 2009-09-05 2013-09-18 山东新时代药业有限公司 一种霉酚酸发酵过程中补糖方法
CN103265514B (zh) * 2013-06-08 2016-01-13 重庆理工大学 一种制备吗替麦考酚酯的方法
CN107056736A (zh) * 2017-05-08 2017-08-18 福建省微生物研究所 一种吗替麦考酚酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748173A (en) * 1987-01-30 1988-05-31 Syntex (U.S.A.) Inc. Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions
HU203678B (en) * 1988-09-26 1991-09-30 Richter Gedeon Vegyeszet Method for increased dewatering condensation reaction mixtures
US5247083A (en) * 1992-07-10 1993-09-21 Syntex (U.S.A.) Inc. Direct esterification of mycophenolic acid

Also Published As

Publication number Publication date
EP1421081A4 (en) 2004-11-03
SK285663B6 (sk) 2007-05-03
JP2004534063A (ja) 2004-11-11
EP1421081A1 (en) 2004-05-26
SK15062003A3 (en) 2004-11-03
CZ292123B6 (cs) 2003-08-13
CA2450013A1 (en) 2002-12-19
WO2002100855A1 (en) 2002-12-19
PL364366A1 (en) 2004-12-13
BR0210931A (pt) 2004-06-08
TWI241299B (en) 2005-10-11
AR041777A1 (es) 2005-06-01
CN1253450C (zh) 2006-04-26
HUP0400189A2 (hu) 2004-07-28
RU2004100227A (ru) 2005-06-27
NZ530013A (en) 2005-05-27
KR20040030660A (ko) 2004-04-09
US20050085635A1 (en) 2005-04-21
RU2283313C2 (ru) 2006-09-10
CN1520411A (zh) 2004-08-11
HK1068630A1 (en) 2005-04-29
HUP0400189A3 (en) 2007-05-29

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of fee

Effective date: 20080608