HUP0304054A2 - A kortikotropin-realising faktor (CRF) antagonistáiként alkalmazható kondenzált pirimidinek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
A kortikotropin-realising faktor (CRF) antagonistáiként alkalmazható kondenzált pirimidinek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0304054A2 HUP0304054A2 HU0304054A HUP0304054A HUP0304054A2 HU P0304054 A2 HUP0304054 A2 HU P0304054A2 HU 0304054 A HU0304054 A HU 0304054A HU P0304054 A HUP0304054 A HU P0304054A HU P0304054 A2 HUP0304054 A2 HU P0304054A2
- Authority
- HU
- Hungary
- Prior art keywords
- crf
- antagonists
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 102000012289 Corticotropin-Releasing Hormone Human genes 0.000 title 1
- 108010022152 Corticotropin-Releasing Hormone Proteins 0.000 title 1
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
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- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0465—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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- C07D471/04—Ortho-condensed systems
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Dermatology (AREA)
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Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0110567A GB0110567D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0110569A GB0110569D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0110570A GB0110570D0 (en) | 2001-04-30 | 2001-04-30 | Chemical compounds |
GB0117399A GB0117399D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0117401A GB0117401D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0117420A GB0117420D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
GB0203201A GB0203201D0 (en) | 2002-02-11 | 2002-02-11 | Chemical compounds |
GB0206834A GB0206834D0 (en) | 2002-03-22 | 2002-03-22 | Chemical compounds |
PCT/GB2002/002029 WO2002088095A1 (en) | 2001-04-30 | 2002-04-30 | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) |
Publications (1)
Publication Number | Publication Date |
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HUP0304054A2 true HUP0304054A2 (hu) | 2004-04-28 |
Family
ID=27571152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0304054A HUP0304054A2 (hu) | 2001-04-30 | 2002-04-30 | A kortikotropin-realising faktor (CRF) antagonistáiként alkalmazható kondenzált pirimidinek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (19)
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002100863A1 (en) * | 2001-06-12 | 2002-12-19 | Glaxo Group Limited | Corticotropin releasing factor antagonists |
GB0117396D0 (en) * | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
EP1583531B1 (en) * | 2003-01-16 | 2007-04-18 | SB Pharmco Puerto Rico Inc | Heteroaryl-substituted pyrrolo[2, 3- b]pyridine derivatives as crf receptor antagonists |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
GB0308208D0 (en) * | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
CN100372851C (zh) * | 2003-05-05 | 2008-03-05 | 弗·哈夫曼-拉罗切有限公司 | 具有crf活性的稠合的嘧啶衍生物 |
JP2007501822A (ja) | 2003-08-12 | 2007-02-01 | エフ.ホフマン−ラ ロシュ アーゲー | コルチコトロピン放出性因子(crf)アンタゴニストとしてのスピロ置換テトラヒドロキナゾリン |
CN100398524C (zh) | 2003-08-12 | 2008-07-02 | 弗·哈夫曼-拉罗切有限公司 | 作为crf拮抗剂的四氢喹唑啉衍生物 |
CA2550948A1 (en) * | 2003-12-22 | 2005-07-14 | Sb Pharmco Puerto Rico Inc. | Crf receptor antagonists and methods relating thereto |
CN1910190A (zh) * | 2004-01-06 | 2007-02-07 | 大正制药株式会社 | 环氨基取代的噻吩并嘧啶和噻吩并吡啶衍生物 |
CA2556946A1 (en) * | 2004-03-05 | 2005-09-15 | Taisho Pharmaceutical Co., Ltd. | Pyrrolopyrimidine derivatives |
MEP8409A (en) | 2004-06-02 | 2011-12-20 | Fused heterocyclic compound | |
BRPI0512514A (pt) * | 2004-06-25 | 2008-03-11 | Taisho Pharmaceutical Co Ltd | composto, antagonista para receptores de crf, e, uso de um composto |
GB0519957D0 (en) * | 2005-09-30 | 2005-11-09 | Sb Pharmco Inc | Chemical compound |
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2002
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- 2002-04-30 ES ES02722478T patent/ES2301633T3/es not_active Expired - Lifetime
- 2002-04-30 IL IL15806202A patent/IL158062A0/xx unknown
- 2002-04-30 PL PL02366934A patent/PL366934A1/xx not_active Application Discontinuation
- 2002-04-30 EP EP02722478A patent/EP1383747B1/en not_active Expired - Lifetime
- 2002-04-30 AR ARP020101597A patent/AR033295A1/es unknown
- 2002-04-30 WO PCT/GB2002/002029 patent/WO2002088095A1/en active IP Right Grant
- 2002-04-30 DE DE60225127T patent/DE60225127T2/de not_active Expired - Fee Related
- 2002-04-30 KR KR10-2003-7014160A patent/KR20040015206A/ko not_active Application Discontinuation
- 2002-04-30 CA CA002446514A patent/CA2446514A1/en not_active Abandoned
- 2002-04-30 HU HU0304054A patent/HUP0304054A2/hu unknown
- 2002-04-30 US US10/476,368 patent/US7279474B2/en not_active Expired - Fee Related
- 2002-04-30 AT AT02722478T patent/ATE386727T1/de not_active IP Right Cessation
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- 2002-04-30 JP JP2002585397A patent/JP2004528349A/ja active Pending
- 2002-04-30 CN CNA028107462A patent/CN1649848A/zh active Pending
- 2002-04-30 AU AU2002253357A patent/AU2002253357B2/en not_active Ceased
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NO20034836D0 (no) | 2003-10-29 |
MXPA03009938A (es) | 2005-09-07 |
ES2301633T3 (es) | 2008-07-01 |
KR20040015206A (ko) | 2004-02-18 |
CA2446514A1 (en) | 2002-11-07 |
IL158062A0 (en) | 2004-03-28 |
AR033295A1 (es) | 2003-12-10 |
PL366934A1 (en) | 2005-02-07 |
EP1383747A1 (en) | 2004-01-28 |
AU2002253357B2 (en) | 2006-08-24 |
NO20034836L (no) | 2003-10-29 |
ATE386727T1 (de) | 2008-03-15 |
WO2002088095A1 (en) | 2002-11-07 |
DE60225127D1 (en) | 2008-04-03 |
CN1649848A (zh) | 2005-08-03 |
CZ20032946A3 (en) | 2004-05-12 |
DE60225127T2 (de) | 2009-02-19 |
BR0209267A (pt) | 2004-06-15 |
US7279474B2 (en) | 2007-10-09 |
JP2004528349A (ja) | 2004-09-16 |
EP1383747B1 (en) | 2008-02-20 |
US20040176400A1 (en) | 2004-09-09 |
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