HUP0303028A2 - Eljárás alkoholok karbamoilezésére - Google Patents

Eljárás alkoholok karbamoilezésére

Info

Publication number
HUP0303028A2
HUP0303028A2 HU0303028A HUP0303028A HUP0303028A2 HU P0303028 A2 HUP0303028 A2 HU P0303028A2 HU 0303028 A HU0303028 A HU 0303028A HU P0303028 A HUP0303028 A HU P0303028A HU P0303028 A2 HUP0303028 A2 HU P0303028A2
Authority
HU
Hungary
Prior art keywords
alcohol
group
carbamoylation
sulfenyl
carbamoylating
Prior art date
Application number
HU0303028A
Other languages
English (en)
Inventor
James Edward Ellis
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of HUP0303028A2 publication Critical patent/HUP0303028A2/hu
Publication of HUP0303028A3 publication Critical patent/HUP0303028A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups

Abstract

A találmány tárgya karbamoilezési eljárás, amelynél egyalkoholvegyületet reagáltatnak nátrium-cianáttal metánszulfonsavjelenlétében. A reakció végezhető vízmentes körülmények között is. Atalálmány szerinti eljárás különösen alkalmas mind alkoholcsoportot,mind bázikus csoportot és/vagy mind alkoholcsoportot, mindszulfenilcsoportot tartalmazó molekulák karbamoilezésére. A találmányszerinti eljárás különösen alkalmas a vírusellenes hatású Capravirineszulfenil-alkohol prekurzurjának karbamoilezésére. Ó
HU0303028A 2001-01-31 2002-01-11 Method for carbamoylating alcohols HUP0303028A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26550201P 2001-01-31 2001-01-31
PCT/IB2002/000082 WO2002060893A1 (en) 2001-01-31 2002-01-11 Method for carbamoylating alcohols

Publications (2)

Publication Number Publication Date
HUP0303028A2 true HUP0303028A2 (hu) 2003-12-29
HUP0303028A3 HUP0303028A3 (en) 2005-10-28

Family

ID=23010706

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303028A HUP0303028A3 (en) 2001-01-31 2002-01-11 Method for carbamoylating alcohols

Country Status (19)

Country Link
US (1) US6613908B2 (hu)
EP (1) EP1377568A1 (hu)
JP (1) JP2004518687A (hu)
KR (1) KR100567706B1 (hu)
CN (1) CN1243748C (hu)
AR (1) AR032419A1 (hu)
BR (1) BR0206806A (hu)
CA (1) CA2433364A1 (hu)
CZ (1) CZ20032001A3 (hu)
HK (1) HK1060573A1 (hu)
HU (1) HUP0303028A3 (hu)
IL (1) IL156363A0 (hu)
MX (1) MXPA03005403A (hu)
PL (1) PL363321A1 (hu)
RU (1) RU2256657C2 (hu)
TW (1) TWI228507B (hu)
WO (1) WO2002060893A1 (hu)
YU (1) YU52303A (hu)
ZA (1) ZA200304687B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7429565B2 (en) 2003-04-25 2008-09-30 Gilead Sciences, Inc. Antiviral phosphonate analogs
JP2007500727A (ja) * 2003-07-30 2007-01-18 ギリアード サイエンシーズ， インコーポレイテッド 抗ウイルス処置のための核酸塩基ホスホネートアナログ
WO2005016912A1 (en) * 2003-08-19 2005-02-24 Pfizer Inc. An efficient microbial preparation of capravirine metabolites m4 and m5
US20050080268A1 (en) * 2003-10-08 2005-04-14 Yong-Moon Choi Process of preparing O-carbamoyl compounds in the presence of active amine group
EP2316839B1 (en) * 2004-07-16 2014-03-12 Gilead Sciences, Inc. Antiviral heterocyclic compounds having phosphonate groups
SI2258376T1 (sl) 2004-07-27 2019-04-30 Gilead Sciences, Inc. Analogi fosfonata spojin inhibitorjev HIV
TW200738742A (en) * 2005-07-14 2007-10-16 Gilead Sciences Inc Antiviral compounds
TWI389908B (zh) * 2005-07-14 2013-03-21 Gilead Sciences Inc 抗病毒化合物類
CA2616314A1 (en) * 2005-07-27 2007-02-01 Gilead Sciences, Inc. Antiviral phosphonate conjugates for inhibition of hiv
WO2008005542A2 (en) * 2006-07-07 2008-01-10 Gilead Sciences, Inc., Antiviral phosphinate compounds
BRPI0915878A2 (pt) * 2008-07-08 2015-11-03 Gilead Sciences Inc sais ou hidratos de compostos inibidores de hiv, seu uso e composição farmacêutica que os compreende
US8810796B2 (en) 2009-04-21 2014-08-19 Michigan Aerospace Corporation Light processing system and method
EP3661937B1 (en) 2017-08-01 2021-07-28 Gilead Sciences, Inc. Crystalline forms of ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate (gs-9131) for treating viral infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2611695A1 (de) * 1976-03-19 1977-09-29 Hoechst Ag Herbizide mittel
KR100387157B1 (ko) 1994-09-26 2003-09-29 시오노기세이야쿠가부시키가이샤 이미다졸유도체

Also Published As

Publication number Publication date
WO2002060893A1 (en) 2002-08-08
KR20030069227A (ko) 2003-08-25
RU2003123791A (ru) 2005-02-27
CZ20032001A3 (en) 2004-06-16
YU52303A (sh) 2006-05-25
PL363321A1 (en) 2004-11-15
MXPA03005403A (es) 2003-09-25
US20020103378A1 (en) 2002-08-01
TWI228507B (en) 2005-03-01
HK1060573A1 (en) 2004-08-13
AR032419A1 (es) 2003-11-05
BR0206806A (pt) 2004-02-03
CA2433364A1 (en) 2002-08-08
CN1243748C (zh) 2006-03-01
KR100567706B1 (ko) 2006-04-05
ZA200304687B (en) 2004-08-10
HUP0303028A3 (en) 2005-10-28
RU2256657C2 (ru) 2005-07-20
US6613908B2 (en) 2003-09-02
EP1377568A1 (en) 2004-01-07
IL156363A0 (en) 2004-01-04
CN1489584A (zh) 2004-04-14
JP2004518687A (ja) 2004-06-24

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees