HUP0303018A2 - Izocianátok, tiocianátok vagy ezek keverékének alkalmazása depigmentálószerként - Google Patents
Izocianátok, tiocianátok vagy ezek keverékének alkalmazása depigmentálószerkéntInfo
- Publication number
- HUP0303018A2 HUP0303018A2 HU0303018A HUP0303018A HUP0303018A2 HU P0303018 A2 HUP0303018 A2 HU P0303018A2 HU 0303018 A HU0303018 A HU 0303018A HU P0303018 A HUP0303018 A HU P0303018A HU P0303018 A2 HUP0303018 A2 HU P0303018A2
- Authority
- HU
- Hungary
- Prior art keywords
- carboxylic acid
- group
- acid ester
- isothiocyanate
- mixture
- Prior art date
Links
- 150000002540 isothiocyanates Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000007854 depigmenting agent Substances 0.000 title 1
- 125000003262 carboxylic acid ester group Chemical group [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 abstract 4
- 150000001732 carboxylic acid derivatives Chemical group 0.000 abstract 3
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
- 150000003462 sulfoxides Chemical class 0.000 abstract 2
- 150000007970 thio esters Chemical class 0.000 abstract 2
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 abstract 1
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002843 carboxylic acid group Chemical group 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000000101 thioether group Chemical group 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
A találmány tárgya (I) általános képletű izotiocianát R1-N=C=S (I) aképletben R1 jelentése alkil-, alkenil-, alkinil-, aril-, acetil-,alkilkarbonil-, alkoxi-, cikloalkil-, ariloxi-, arilkarbonil-,karbonsav vagy karbonsav-észtercsoport vagy egy -(CH2)nR3 csoport,ahol n értéke 1-5 közötti szám és R3 jelentése egy poláros, funkcióscsoport, előnyösen halogénatom vagy szulfoxid-, karbonil-, nitro-,tio-észter-, tio-éter-, szulfonil-, szulfinil-, nitril-, karbonsav-,karbonsav-észter-, alkiltio- vagy hidroxilcsoport -, vagy egy (II)általános képletű tiocianát R2-S=C=N (II) a képletben R2 jelentésealkil-, alkenil-, alkinil-, aril-, acetil-, alkilkarbonil-, alkoxi-,cikloalkil-, ariloxi-, arilkarbonil-, karbonsav- vagy karbonsav-észtercsoport vagy egy -(CH2)nR3 csoport, ahol n értéke 1-től 5-igterjedő szám és R3 jelentése egy poláros funkciós csoport, előnyösenhalogénatom vagy egy szulfoxid-, karbonil-, nitro-, tio-észter-, tio-éter-, szulfonil-, szulfinil-, nitril-, karbonsav-, karbonsav-észter-,alkiltio- vagy hidroxilcsoport vagy ezek keverékének alkalmazásatyrozináz gátlására szolgáló gyógyszerkészítmény vagy kozmetikaikészítmény előállításánál. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0101078A FR2820036B1 (fr) | 2001-01-26 | 2001-01-26 | Utilisation d'un isothiocyanate, d'un thiocyanate ou de leur melange en tant que depigmentant |
| PCT/FR2002/000288 WO2002058664A1 (fr) | 2001-01-26 | 2002-01-24 | Utilisation d'un isothiocyanate, d'un thiocyanate ou de leur melange en tant que depigmentant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0303018A2 true HUP0303018A2 (hu) | 2003-12-29 |
Family
ID=8859278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0303018A HUP0303018A2 (hu) | 2001-01-26 | 2002-01-24 | Izocianátok, tiocianátok vagy ezek keverékének alkalmazása depigmentálószerként |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20040077715A1 (hu) |
| EP (1) | EP1353644A1 (hu) |
| JP (1) | JP2004520371A (hu) |
| KR (1) | KR20030086256A (hu) |
| CA (1) | CA2435942A1 (hu) |
| CZ (1) | CZ20032012A3 (hu) |
| FR (1) | FR2820036B1 (hu) |
| HU (1) | HUP0303018A2 (hu) |
| MX (1) | MXPA03006731A (hu) |
| PL (1) | PL364826A1 (hu) |
| SK (1) | SK9612003A3 (hu) |
| WO (1) | WO2002058664A1 (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2845599B1 (fr) * | 2002-10-11 | 2005-01-07 | Lmd | Medicament comprenant une thiouree pour son utilisation en tant que depigmentant |
| FR2879444B1 (fr) * | 2004-12-22 | 2007-05-18 | Oreal | Utilisation d'un compose capable d'augmenter le taux de glutathion dans les melanocytes pour le traitement de la canitie |
| FR2880022B1 (fr) * | 2004-12-24 | 2007-08-24 | Mayoly Spindler Soc Par Action | Nouveaux derives de la n-hydroxy-n'-phenyluree et de la n-hydroxy-n'-phenylthiouree et leur utilisation comme inhibiteurs de la synthese de la melanine |
| DE102008047362A1 (de) * | 2008-09-15 | 2010-04-15 | Henkel Ag & Co. Kgaa | Zusammensetzung zur Hautaufhellung |
| BE1019434A3 (fr) * | 2010-07-23 | 2012-07-03 | Auriga Internat | Stabilisation du sulforaphane. |
| BE1019431A3 (fr) * | 2010-07-23 | 2012-07-03 | Auriga Internat | Procede de synthese d'isothiocyanates et leurs derives et utilisations de ceux-ci. |
| US20140030201A1 (en) * | 2010-12-21 | 2014-01-30 | Rebecca Susan Ginger | A skin lightening composition |
| DE102012222970A1 (de) * | 2012-12-12 | 2014-06-12 | Henkel Ag & Co. Kgaa | Wirkstoffkombination zur Hautaufhellung I |
| WO2015002279A1 (ja) * | 2013-07-03 | 2015-01-08 | 味の素株式会社 | グルタチオン生成促進用組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8903954A (pt) * | 1989-08-01 | 1991-02-05 | Chiaki Ohama | Cosmetico inibidor da formacao de melanina |
| JPH05163135A (ja) * | 1991-12-16 | 1993-06-29 | Suntory Ltd | 美白用化粧料組成物 |
| JPH05213857A (ja) * | 1992-01-31 | 1993-08-24 | Kao Corp | メラニン抑制剤 |
| JP3601875B2 (ja) * | 1995-05-29 | 2004-12-15 | 共栄化学工業株式会社 | 化粧料 |
| FR2769837B1 (fr) * | 1997-10-17 | 2000-02-25 | Bio Sphere 99 Lab | Composition pour dietetique ou cosmetique a base d'extraits vegetaux |
-
2001
- 2001-01-26 FR FR0101078A patent/FR2820036B1/fr not_active Expired - Fee Related
-
2002
- 2002-01-24 CA CA002435942A patent/CA2435942A1/fr not_active Abandoned
- 2002-01-24 PL PL02364826A patent/PL364826A1/xx not_active Application Discontinuation
- 2002-01-24 WO PCT/FR2002/000288 patent/WO2002058664A1/fr not_active Application Discontinuation
- 2002-01-24 JP JP2002558998A patent/JP2004520371A/ja active Pending
- 2002-01-24 KR KR10-2003-7009921A patent/KR20030086256A/ko not_active Application Discontinuation
- 2002-01-24 HU HU0303018A patent/HUP0303018A2/hu unknown
- 2002-01-24 CZ CZ20032012A patent/CZ20032012A3/cs unknown
- 2002-01-24 MX MXPA03006731A patent/MXPA03006731A/es unknown
- 2002-01-24 US US10/470,079 patent/US20040077715A1/en not_active Abandoned
- 2002-01-24 EP EP02700395A patent/EP1353644A1/fr not_active Withdrawn
- 2002-01-24 SK SK961-2003A patent/SK9612003A3/sk unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20040077715A1 (en) | 2004-04-22 |
| PL364826A1 (en) | 2004-12-27 |
| JP2004520371A (ja) | 2004-07-08 |
| FR2820036A1 (fr) | 2002-08-02 |
| MXPA03006731A (es) | 2004-10-15 |
| SK9612003A3 (en) | 2004-03-02 |
| WO2002058664A1 (fr) | 2002-08-01 |
| CA2435942A1 (fr) | 2002-08-01 |
| KR20030086256A (ko) | 2003-11-07 |
| EP1353644A1 (fr) | 2003-10-22 |
| CZ20032012A3 (cs) | 2004-01-14 |
| FR2820036B1 (fr) | 2005-12-09 |
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