MA28358A1 - Inhibiteurs de l'integrase du vih - Google Patents

Inhibiteurs de l'integrase du vih

Info

Publication number
MA28358A1
MA28358A1 MA29263A MA29263A MA28358A1 MA 28358 A1 MA28358 A1 MA 28358A1 MA 29263 A MA29263 A MA 29263A MA 29263 A MA29263 A MA 29263A MA 28358 A1 MA28358 A1 MA 28358A1
Authority
MA
Morocco
Prior art keywords
inhibitors
hiv integrase
integrase
hiv
Prior art date
Application number
MA29263A
Other languages
English (en)
Inventor
Brian Alvin Johns
Eric Eugene Boros
Takashi Kawasuji
Cecilia S Koble
Noriyuki Kurose
Hitoshi Murai
Ronald George Sherrill
Jason Gordon Weatherhead
Original Assignee
Smithkline Beecham Corp
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Shionogi & Co filed Critical Smithkline Beecham Corp
Publication of MA28358A1 publication Critical patent/MA28358A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA29263A 2004-02-11 2006-08-11 Inhibiteurs de l'integrase du vih MA28358A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54367004P 2004-02-11 2004-02-11

Publications (1)

Publication Number Publication Date
MA28358A1 true MA28358A1 (fr) 2006-12-01

Family

ID=34860447

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29263A MA28358A1 (fr) 2004-02-11 2006-08-11 Inhibiteurs de l'integrase du vih

Country Status (15)

Country Link
US (3) US8691991B2 (fr)
EP (1) EP1720856B1 (fr)
JP (1) JP4859676B2 (fr)
KR (1) KR20070002006A (fr)
CN (1) CN1976915A (fr)
AU (1) AU2005211733A1 (fr)
BR (1) BRPI0507628A (fr)
CA (1) CA2555176A1 (fr)
ES (1) ES2433477T3 (fr)
IL (1) IL177189A0 (fr)
MA (1) MA28358A1 (fr)
MX (1) MXPA06009132A (fr)
NO (1) NO20063958L (fr)
RU (1) RU2006128848A (fr)
WO (1) WO2005077050A2 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1720856B1 (fr) 2004-02-11 2013-08-14 GlaxoSmithKline LLC Inhibiteurs de l'integrase du vih
ES2567197T3 (es) 2005-04-28 2016-04-20 Viiv Healthcare Company Derivado de carbamoilpiridona policíclico que tiene actividad inhibidora de la integrasa del VIH
US20080214503A1 (en) * 2005-08-04 2008-09-04 Smithkline Beecham Corporation Hiv Integrase Inhibitors
US20080194523A1 (en) * 2005-08-04 2008-08-14 Smithkline Beecham Corporation Hiv Integrase Inhibitors
WO2007019130A2 (fr) * 2005-08-04 2007-02-15 Smithkline Beecham Corporation Inhibiteurs d'integrase du vih
WO2007019098A2 (fr) * 2005-08-04 2007-02-15 Smithkline Beecham Corporation Inhibiteurs de l'integrase du vih
TW200808793A (en) * 2006-03-07 2008-02-16 Smithkline Beecham Corp Prolyl hydroxylase inhibitors
KR101409261B1 (ko) * 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 신규의 복소환 화합물 또는 그 염 및 그 중간체
EP1956016A1 (fr) * 2006-12-15 2008-08-13 Bayer Schering Pharma Aktiengesellschaft Acyltryptophanols
AU2007334323B2 (en) 2006-12-18 2011-03-10 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
EP2097416B1 (fr) 2006-12-18 2012-09-12 Amgen, Inc Composés d'azaquinolone possédant une activité inhibitrice de prolyl hydroxylase, compositions et utilisations correspondantes
WO2008130600A2 (fr) 2007-04-18 2008-10-30 Amgen Inc. Quinolones et azaquinolones inhibant la prolyl hydroxylase
AU2008241577B2 (en) 2007-04-18 2011-04-07 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
CA2683758A1 (fr) * 2007-04-18 2008-10-30 Merck & Co., Inc. Nouveaux composes de type 1,8-naphthyridine
WO2008137060A1 (fr) 2007-05-04 2008-11-13 Amgen Inc. Dérivés de la thienopyridine et de la thiazolopyridine qui inhibent l'activité prolyle hydroxylase
EP2155746A2 (fr) 2007-05-04 2010-02-24 Amgen, Inc Diazaquinolones inhibant l'activité de la prolyl hydroxylase
WO2010011819A1 (fr) * 2008-07-25 2010-01-28 Smithkline Beecham Corporation Composés chimiques
WO2010011818A1 (fr) * 2008-07-25 2010-01-28 Smithkline Beecham Corporation Composés chimiques
US8283366B2 (en) 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase
KR20170078868A (ko) 2010-01-27 2017-07-07 비이브 헬쓰케어 컴퍼니 항바이러스 치료
US20110223131A1 (en) * 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
MY175079A (en) * 2010-04-02 2020-06-04 Firmenich Incorporated Sweet flavor modifier
RU2013120556A (ru) 2010-10-14 2014-11-20 Иммунар Аб 1,2-гидрокси-2-оксо-хинолин-3-карбоксанилиды в качестве активаторов ahr
US9359300B2 (en) 2010-12-06 2016-06-07 Confluence Life Sciences, Inc. Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds
JP5848775B2 (ja) 2010-12-06 2016-01-27 コンフルエンス・ライフ・サイエンシズ，インコーポレーテッド 置換ピリジノンピリジニル化合物
EP2703399A4 (fr) 2011-04-26 2014-10-15 Shionogi & Co Dérivé d'oxazine et inhibiteur de bace 1 le contenant
MX336378B (es) 2011-08-12 2016-01-15 Senomyx Inc Modificador del sabor dulce.
ES2926068T3 (es) 2012-12-21 2022-10-21 Gilead Sciences Inc Compuestos de carbamoilpiridona policíclicos y su uso farmacéutico
KR102653785B1 (ko) 2013-06-07 2024-04-01 어클라리스 쎄라퓨틱스, 인코포레이티드 메틸/플루오로-피리디닐-메톡시 치환된 피리디논-피리디닐 화합물 및 플루오로-피리미디닐-메톡시 치환된 피리디논-피리디닐 화합물
BR112017008738B1 (pt) 2014-11-07 2021-06-15 Firmenich Incorporated Ácidos 4-amino-5-(ciclohexilóxi)quinolina-3-carboxílicos substituídos como modificadores de sabores adoçantes
CN105348282B (zh) * 2015-12-02 2018-06-29 北京工业大学 一种hiv-1整合酶抑制剂化合物及其制备方法和应用
US11844801B2 (en) 2020-03-27 2023-12-19 Aclaris Therapeutics, Inc. Oral compositions of MK2 pathway inhibitor for treatment of immune conditions
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002246499B2 (en) 2000-10-12 2005-12-22 Merck & Co., Inc. Aza-and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors
EP1326611B1 (fr) * 2000-10-12 2007-06-13 Merck & Co., Inc. Azanaphthalenylcarboxamides et polyazanaphthalenylcarboxamides utiles en tant qu'inhibiteurs de la vih integrase
AU2002230392A1 (en) 2000-10-12 2002-05-15 Merck & Co., Inc. AZA-and polyaza-naphthalenyl ketones useful as HIV integrase inhibitors
IL155089A0 (en) 2000-10-12 2003-10-31 Merck & Co Inc Aza and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
HUP0400175A2 (en) 2001-03-01 2007-07-30 Shionogi & Co Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity, their use and pharmaceutical compositions containing them
DE60315796T2 (de) 2002-01-17 2008-06-05 Merck & Co., Inc. Hydroxynaphthyridinoncarbonsäureamide, die sich als inhibitoren der hiv-integrase eignen
EP1541558B1 (fr) 2002-08-13 2008-08-13 Shionogi & Co., Ltd. Composes heterocycliques a activite inhibitrice de l'integrase du vih
CA2495914A1 (fr) 2002-08-29 2004-03-11 Merck & Co., Inc. Derives n-biarylmethyl aminocycloalcanecarboxamide
AR043633A1 (es) 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
WO2005023189A2 (fr) 2003-09-03 2005-03-17 Pharmacia Corporation Procede de prevention ou de traitement de la douleur, de l'inflammation, et de troubles lies a l'inflammation avec un inhibiteur selectif de cox-2 en combinaison avec un agent donneur de monoxyde d'azote et compositions en contenant
EP1664046B1 (fr) 2003-09-19 2009-06-17 Gilead Sciences, Inc. Composes d'aza-quinolinol phosphonate inhibiteurs de l'integrase
EP1720856B1 (fr) 2004-02-11 2013-08-14 GlaxoSmithKline LLC Inhibiteurs de l'integrase du vih

Also Published As

Publication number Publication date
CN1976915A (zh) 2007-06-06
ES2433477T3 (es) 2013-12-11
US20070124152A1 (en) 2007-05-31
EP1720856A4 (fr) 2009-11-11
WO2005077050A3 (fr) 2006-11-23
US20140256713A1 (en) 2014-09-11
US8691991B2 (en) 2014-04-08
US20150225399A1 (en) 2015-08-13
BRPI0507628A (pt) 2007-07-03
RU2006128848A (ru) 2008-03-20
JP2007523086A (ja) 2007-08-16
KR20070002006A (ko) 2007-01-04
NO20063958L (no) 2006-09-22
EP1720856B1 (fr) 2013-08-14
AU2005211733A1 (en) 2005-08-25
MXPA06009132A (es) 2007-03-26
CA2555176A1 (fr) 2005-08-25
WO2005077050A2 (fr) 2005-08-25
IL177189A0 (en) 2006-12-10
EP1720856A2 (fr) 2006-11-15
JP4859676B2 (ja) 2012-01-25

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