HUP0302601A3 - Mutant allergens - Google Patents
Mutant allergensInfo
- Publication number
- HUP0302601A3 HUP0302601A3 HU0302601A HUP0302601A HUP0302601A3 HU P0302601 A3 HUP0302601 A3 HU P0302601A3 HU 0302601 A HU0302601 A HU 0302601A HU P0302601 A HUP0302601 A HU P0302601A HU P0302601 A3 HUP0302601 A3 HU P0302601A3
- Authority
- HU
- Hungary
- Prior art keywords
- mutant allergens
- allergens
- mutant
- Prior art date
Links
- 239000013566 allergen Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43568—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from wasps
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43572—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Insects & Arthropods (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Botany (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Transplantation (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24936100P | 2000-11-16 | 2000-11-16 | |
DKPA200001718 | 2000-11-16 | ||
US29817001P | 2001-06-14 | 2001-06-14 | |
PCT/DK2001/000764 WO2002040676A2 (en) | 2000-11-16 | 2001-11-16 | Mutant allergens |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0302601A2 HUP0302601A2 (hu) | 2003-11-28 |
HUP0302601A3 true HUP0302601A3 (en) | 2010-01-28 |
Family
ID=27222455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302601A HUP0302601A3 (en) | 2000-11-16 | 2001-11-16 | Mutant allergens |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1373510B1 (hu) |
JP (1) | JP2004521618A (hu) |
KR (1) | KR100919914B1 (hu) |
CN (1) | CN100577804C (hu) |
AT (1) | ATE414773T1 (hu) |
AU (2) | AU2350502A (hu) |
CA (1) | CA2429172C (hu) |
CZ (1) | CZ20031653A3 (hu) |
DE (1) | DE60136653D1 (hu) |
DK (1) | DK1373510T3 (hu) |
ES (1) | ES2317955T3 (hu) |
HK (1) | HK1060371A1 (hu) |
HU (1) | HUP0302601A3 (hu) |
MX (1) | MXPA03004174A (hu) |
NO (1) | NO329721B1 (hu) |
NZ (1) | NZ525820A (hu) |
PL (1) | PL214225B1 (hu) |
WO (1) | WO2002040676A2 (hu) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2116257T3 (da) | 2000-08-09 | 2013-02-04 | Alk Abello As | Parenterale vaccineformuleringer og anvendelser deraf |
CN1668737A (zh) * | 2002-05-16 | 2005-09-14 | 阿尔克-阿贝洛有限公司 | 重组Bet.V.1过敏原突变体及其方法和制备 |
FR2841906B1 (fr) * | 2002-07-05 | 2006-08-18 | Stallergenes Sa | Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes |
JP2006520184A (ja) | 2002-11-01 | 2006-09-07 | アルカベロ アクチェセルスカプ | 組換えタンパク質変種 |
MXPA05005528A (es) | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
MXPA05009079A (es) | 2003-02-28 | 2006-05-19 | Alk Abello As | Forma de dosificacion que tiene una matriz de sacarido. |
US8012505B2 (en) | 2003-02-28 | 2011-09-06 | Alk-Abello A/S | Dosage form having a saccharide matrix |
PT2272863E (pt) * | 2003-06-04 | 2013-01-30 | Merck Patent Gmbh | Derivados de phl p 5a com alergenicidade reduzida e reatividade da célula t retida |
CN1894026B (zh) * | 2003-12-19 | 2012-01-25 | 阿尔克-阿贝洛有限公司 | 用于活性药剂的低温制粒和贮藏的方法 |
RU2006126051A (ru) | 2003-12-19 | 2008-01-27 | Альк-Абелло А/С (Dk) | Способы получения партии активного фармацевтического ингредиента, контейнер, содержащий криогранулы аллергенного продукта, и криогранула аллергенного продукта |
EP1756150A2 (en) * | 2004-04-23 | 2007-02-28 | Novozymes A/S | Group 1 mite polypeptide variants |
US20060115499A1 (en) * | 2004-09-27 | 2006-06-01 | Alk-Abello A/S | Liquid allergy vaccine formulation for oromucosal administration |
US20060121063A1 (en) * | 2004-10-22 | 2006-06-08 | Novozymes A/S | Group 2 mite polypeptide variants |
EP1868642B1 (en) | 2005-03-18 | 2013-05-08 | Cytos Biotechnology AG | Cat allergen fusion proteins and uses thereof |
CA2624503A1 (en) | 2005-10-04 | 2007-04-12 | Alk-Abello A/S | Solid vaccine formulation |
CN103933562A (zh) * | 2005-11-04 | 2014-07-23 | 爱尔开-阿贝优公司 | 用于口腔粘膜给药的液体变态反应性疫苗制剂的用途 |
CA2628226A1 (en) * | 2005-11-04 | 2007-05-10 | Alk-Abello A/S | Use of a liquid allergy vaccine formulation for oromucosal administration |
ITMI20052517A1 (it) * | 2005-12-29 | 2007-06-30 | Lofarma Spa | Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa |
AT503297B1 (de) * | 2006-05-18 | 2007-09-15 | Biomay Ag | Allergen-spezifische antikörper |
AT503690A1 (de) | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
EP1908777B1 (en) * | 2006-10-06 | 2016-02-03 | Stallergenes | Mite fusion proteins |
AU2008231722B2 (en) | 2007-03-28 | 2013-09-12 | Alk-Abello A/S | Use of an adjuvanted allergy vaccine formulation for parenteral administration |
SI2083856T1 (sl) | 2007-08-15 | 2011-02-28 | Circassia Ltd | Peptidi za desenzibilizacijo proti alergijam |
DE202008006598U1 (de) | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
WO2010146171A1 (en) | 2009-06-19 | 2010-12-23 | Alk-Abelló A/S | Novel manner of administering allergen in allergen specific immunotherapy |
EP3170510A1 (de) * | 2010-01-14 | 2017-05-24 | Merck Patent GmbH | Varianten der gruppe 5-allergene der süssgräser mit reduzierter allergenität durch mutagenese von prolinresten |
EP2388268A1 (en) * | 2010-05-18 | 2011-11-23 | Stallergenes S.A. | Recombinant Der p 2 expressed in Pichia pastoris as a "natural-like" allergen for immunotherapy and diagnostic purposes |
FI20115375A0 (fi) | 2011-04-18 | 2011-04-18 | Teknologian Tutkimuskeskus Vtt Oy | Uudet hypoallergeenit |
FI20115374A0 (fi) | 2011-04-18 | 2011-04-18 | Teknologian Tutkimuskeskus Vtt Oy | Uudet hypoallergeenit |
ITMI20112301A1 (it) * | 2011-12-19 | 2013-06-20 | Lofarma Spa | Varianti ipoallergeniche dell'allergene maggiore phl p 5 di phleum pratense |
EP2692732A1 (en) | 2012-08-03 | 2014-02-05 | Stallergenes S.A. | Novel allergen from ragweed pollen and uses thereof |
RU2687164C2 (ru) | 2012-10-30 | 2019-05-07 | Аравакс Пти Лтд | Новые иммунотерапевтические молекулы и их применения |
CA2914037A1 (en) * | 2013-06-06 | 2014-12-11 | Anergis S.A. | Contiguous overlapping peptides for treatment of house dust mites allergy |
WO2015044789A2 (en) | 2013-09-24 | 2015-04-02 | Fibar Group sp. z o.o. | Intelligent smoke sensor |
BR112016006813A2 (pt) | 2013-09-25 | 2017-09-19 | Aravax Pty Ltd | Composição imunoterapêutica nova e seus usos |
EP2952200A1 (en) | 2014-06-04 | 2015-12-09 | Alk-Abelló A/S | Allergen for prophylactic treatment of allergy |
US9898175B2 (en) | 2014-08-05 | 2018-02-20 | Fibar Group S.A. | Home network manager for home automation |
EP3269730A1 (en) * | 2016-07-12 | 2018-01-17 | Universität Salzburg | Allergen variant |
WO2018210896A1 (en) | 2017-05-19 | 2018-11-22 | F. Hoffmann-La Roche Ag | Method for the production of thymocyte supernatant |
CN110093336B (zh) * | 2018-01-29 | 2023-03-24 | 上海雅心生物技术有限公司 | 一种稳定的胰蛋白酶及其制备方法 |
RU2761431C9 (ru) | 2020-10-26 | 2022-04-18 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии |
WO2023242436A1 (en) * | 2022-06-17 | 2023-12-21 | Danmarks Tekniske Universitet | Allergy vaccines based on consensus allergens |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1874997A (en) * | 1996-02-15 | 1997-09-02 | Pangenetics B.V. | Molecules for the induction of immunological tolerance |
DE19713001A1 (de) * | 1997-03-27 | 1998-10-01 | Merck Patent Gmbh | Graminaenpollenallergenmutanten zur spezifischen Immuntherapie, deren Herstellung und Verwendung |
DE69940805D1 (de) * | 1998-01-31 | 2009-06-10 | Sinai School Medicine | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
CA2323687C (en) * | 1998-03-16 | 2008-11-25 | Alk-Abello A/S | Mutant recombinant allergens |
-
2001
- 2001-11-16 KR KR1020037006644A patent/KR100919914B1/ko not_active IP Right Cessation
- 2001-11-16 PL PL362273A patent/PL214225B1/pl not_active IP Right Cessation
- 2001-11-16 AU AU2350502A patent/AU2350502A/xx active Pending
- 2001-11-16 CA CA2429172A patent/CA2429172C/en not_active Expired - Fee Related
- 2001-11-16 CZ CZ20031653A patent/CZ20031653A3/cs unknown
- 2001-11-16 EP EP01996610A patent/EP1373510B1/en not_active Expired - Lifetime
- 2001-11-16 WO PCT/DK2001/000764 patent/WO2002040676A2/en active IP Right Grant
- 2001-11-16 MX MXPA03004174A patent/MXPA03004174A/es active IP Right Grant
- 2001-11-16 AT AT01996610T patent/ATE414773T1/de active
- 2001-11-16 NZ NZ525820A patent/NZ525820A/en not_active IP Right Cessation
- 2001-11-16 AU AU2002223505A patent/AU2002223505B2/en not_active Ceased
- 2001-11-16 JP JP2002543671A patent/JP2004521618A/ja active Pending
- 2001-11-16 ES ES01996610T patent/ES2317955T3/es not_active Expired - Lifetime
- 2001-11-16 HU HU0302601A patent/HUP0302601A3/hu unknown
- 2001-11-16 DK DK01996610T patent/DK1373510T3/da active
- 2001-11-16 DE DE60136653T patent/DE60136653D1/de not_active Expired - Lifetime
- 2001-11-16 CN CN01820783A patent/CN100577804C/zh not_active Expired - Fee Related
-
2003
- 2003-05-15 NO NO20032213A patent/NO329721B1/no not_active IP Right Cessation
-
2004
- 2004-05-14 HK HK04103424.6A patent/HK1060371A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2350502A (en) | 2002-05-27 |
KR100919914B1 (ko) | 2009-10-06 |
HK1060371A1 (en) | 2004-08-06 |
CA2429172A1 (en) | 2002-05-23 |
CN1484699A (zh) | 2004-03-24 |
CA2429172C (en) | 2012-03-20 |
CN100577804C (zh) | 2010-01-06 |
DK1373510T3 (da) | 2009-02-23 |
ES2317955T3 (es) | 2009-05-01 |
DE60136653D1 (de) | 2009-01-02 |
KR20030076577A (ko) | 2003-09-26 |
MXPA03004174A (es) | 2004-12-02 |
NO20032213D0 (no) | 2003-05-15 |
PL214225B1 (pl) | 2013-07-31 |
WO2002040676A2 (en) | 2002-05-23 |
HUP0302601A2 (hu) | 2003-11-28 |
PL362273A1 (en) | 2004-10-18 |
NO329721B1 (no) | 2010-12-06 |
ATE414773T1 (de) | 2008-12-15 |
CZ20031653A3 (en) | 2004-03-17 |
JP2004521618A (ja) | 2004-07-22 |
NZ525820A (en) | 2005-01-28 |
AU2002223505B2 (en) | 2006-12-07 |
EP1373510B1 (en) | 2008-11-19 |
NO20032213L (no) | 2003-07-02 |
WO2002040676A3 (en) | 2003-10-09 |
EP1373510A2 (en) | 2004-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |