HUP0300183A3 - Substituted purine derivatives as inhibitors of cell adhesion - Google Patents
Substituted purine derivatives as inhibitors of cell adhesionInfo
- Publication number
- HUP0300183A3 HUP0300183A3 HU0300183A HUP0300183A HUP0300183A3 HU P0300183 A3 HUP0300183 A3 HU P0300183A3 HU 0300183 A HU0300183 A HU 0300183A HU P0300183 A HUP0300183 A HU P0300183A HU P0300183 A3 HUP0300183 A3 HU P0300183A3
- Authority
- HU
- Hungary
- Prior art keywords
- inhibitors
- cell adhesion
- purine derivatives
- substituted purine
- substituted
- Prior art date
Links
- 230000021164 cell adhesion Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99112637A EP1065208A1 (en) | 1999-07-02 | 1999-07-02 | Substituted purine derivatives as inhibitors of cell adhesion |
| PCT/EP2000/005921 WO2001002399A1 (en) | 1999-07-02 | 2000-06-26 | Substituted purine derivatives as inhibitors of cell adhesion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0300183A2 HUP0300183A2 (hu) | 2003-06-28 |
| HUP0300183A3 true HUP0300183A3 (en) | 2005-12-28 |
Family
ID=8238483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0300183A HUP0300183A3 (en) | 1999-07-02 | 2000-06-26 | Substituted purine derivatives as inhibitors of cell adhesion |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6747016B1 (hu) |
| EP (2) | EP1065208A1 (hu) |
| JP (1) | JP2003503497A (hu) |
| KR (1) | KR20020015997A (hu) |
| CN (1) | CN1171888C (hu) |
| AR (1) | AR034242A1 (hu) |
| AT (1) | ATE262528T1 (hu) |
| AU (1) | AU774382B2 (hu) |
| BG (1) | BG106229A (hu) |
| BR (1) | BR0012050A (hu) |
| CA (1) | CA2376673A1 (hu) |
| CZ (1) | CZ20014553A3 (hu) |
| DE (1) | DE60009296T2 (hu) |
| EA (1) | EA005372B1 (hu) |
| EE (1) | EE200100713A (hu) |
| ES (1) | ES2219353T3 (hu) |
| HU (1) | HUP0300183A3 (hu) |
| IL (1) | IL147245A0 (hu) |
| MX (1) | MXPA01013241A (hu) |
| MY (1) | MY122631A (hu) |
| NO (1) | NO20016403L (hu) |
| NZ (1) | NZ516095A (hu) |
| PL (1) | PL352281A1 (hu) |
| SK (1) | SK18792001A3 (hu) |
| TR (1) | TR200103858T2 (hu) |
| TW (1) | TWI229080B (hu) |
| UA (1) | UA72923C2 (hu) |
| WO (1) | WO2001002399A1 (hu) |
| YU (1) | YU89701A (hu) |
| ZA (1) | ZA200200017B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10042655A1 (de) * | 2000-08-31 | 2002-03-14 | Aventis Pharma Gmbh | Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion |
| FR2847254B1 (fr) * | 2002-11-19 | 2005-01-28 | Aventis Pharma Sa | Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant |
| FR2870541B1 (fr) * | 2004-05-18 | 2006-07-14 | Proskelia Sas | Derives de pyrimidines antigonistes du recepteur de la vitronectine |
| CN103265495B (zh) * | 2005-12-29 | 2016-11-16 | 莱西肯医药有限公司 | 多环氨基酸衍生物及其使用方法 |
| CL2007002994A1 (es) * | 2006-10-19 | 2008-02-08 | Wyeth Corp | Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros. |
| CN107450106A (zh) * | 2017-09-28 | 2017-12-08 | 北京小米移动软件有限公司 | 饮水安全提示方法、装置及智能水杯 |
| WO2021226261A1 (en) | 2020-05-06 | 2021-11-11 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
| TW202241889A (zh) | 2020-12-23 | 2022-11-01 | 美商雅捷可斯治療公司 | 作為ｊａｋ２抑制劑之６－雜芳基氧基苯并咪唑及氮雜苯并咪唑 |
| CA3234638A1 (en) | 2021-11-09 | 2023-05-19 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE227567T1 (de) * | 1994-05-27 | 2002-11-15 | Merck & Co Inc | Präparate zur hemmung der durch osteoklasten vermittelten knochenresorption |
| WO1998008840A1 (en) * | 1996-08-29 | 1998-03-05 | Merck & Co., Inc. | Integrin antagonists |
| WO1998018461A1 (en) * | 1996-10-30 | 1998-05-07 | Merck & Co., Inc. | Integrin antagonists |
| DE19653646A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Substituierte Purinderivate, Verfahren zu deren Herstellung, sie enthaltende Mittel und deren Verwendung |
| JP2001509176A (ja) * | 1997-01-17 | 2001-07-10 | メルク エンド カンパニー インコーポレーテッド | インテグリンアンタゴニスト |
| EP1049677A1 (en) * | 1998-01-23 | 2000-11-08 | Aventis Pharma Deutschland GmbH | Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion |
| AU2610099A (en) | 1998-01-28 | 1999-08-16 | Danmist Aps | Method of piezoelectrically atomising and pumping fluids and piezoelectric fluidatomising and pumping device |
-
1999
- 1999-07-02 EP EP99112637A patent/EP1065208A1/en not_active Withdrawn
-
2000
- 2000-06-26 EE EEP200100713A patent/EE200100713A/xx unknown
- 2000-06-26 ES ES00940406T patent/ES2219353T3/es not_active Expired - Lifetime
- 2000-06-26 NZ NZ516095A patent/NZ516095A/en unknown
- 2000-06-26 CN CNB008121001A patent/CN1171888C/zh not_active Expired - Fee Related
- 2000-06-26 HU HU0300183A patent/HUP0300183A3/hu unknown
- 2000-06-26 UA UA2002020851A patent/UA72923C2/uk unknown
- 2000-06-26 EA EA200200121A patent/EA005372B1/ru not_active IP Right Cessation
- 2000-06-26 MX MXPA01013241A patent/MXPA01013241A/es active IP Right Grant
- 2000-06-26 AT AT00940406T patent/ATE262528T1/de not_active IP Right Cessation
- 2000-06-26 KR KR1020017016962A patent/KR20020015997A/ko not_active Application Discontinuation
- 2000-06-26 IL IL14724500A patent/IL147245A0/xx unknown
- 2000-06-26 PL PL00352281A patent/PL352281A1/xx not_active Application Discontinuation
- 2000-06-26 AU AU55349/00A patent/AU774382B2/en not_active Ceased
- 2000-06-26 US US10/030,290 patent/US6747016B1/en not_active Expired - Fee Related
- 2000-06-26 JP JP2001507836A patent/JP2003503497A/ja not_active Withdrawn
- 2000-06-26 BR BR0012050-2A patent/BR0012050A/pt not_active IP Right Cessation
- 2000-06-26 DE DE60009296T patent/DE60009296T2/de not_active Expired - Fee Related
- 2000-06-26 CZ CZ20014553A patent/CZ20014553A3/cs unknown
- 2000-06-26 WO PCT/EP2000/005921 patent/WO2001002399A1/en not_active Application Discontinuation
- 2000-06-26 TR TR2001/03858T patent/TR200103858T2/xx unknown
- 2000-06-26 CA CA002376673A patent/CA2376673A1/en not_active Abandoned
- 2000-06-26 EP EP00940406A patent/EP1196416B1/en not_active Expired - Lifetime
- 2000-06-26 SK SK1879-2001A patent/SK18792001A3/sk unknown
- 2000-06-29 AR ARP000103314A patent/AR034242A1/es not_active Application Discontinuation
- 2000-06-29 MY MYPI20002961A patent/MY122631A/en unknown
- 2000-09-01 TW TW089117924A patent/TWI229080B/zh not_active IP Right Cessation
-
2001
- 2001-12-17 BG BG106229A patent/BG106229A/bg unknown
- 2001-12-19 YU YU89701A patent/YU89701A/sh unknown
- 2001-12-28 NO NO20016403A patent/NO20016403L/no not_active Application Discontinuation
-
2002
- 2002-01-02 ZA ZA200200017A patent/ZA200200017B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU5152100A (en) | Substituted beta-alanine derivatives as cell adhesion inhibitors | |
| AU6903200A (en) | Heterocycle amides as cell adhesion inhibitors | |
| AP2001002218A0 (en) | The use of 4-h-1- benzopyran-4-one derivatives as inhibitors of smooth muscle cell proliferation | |
| AU6909300A (en) | Substituted ureas as cell adhesion inhibitors | |
| HUP0202450A3 (en) | N-heterocyclic derivatives as nos inhibitors | |
| PL339173A1 (en) | Derivatives of benzamidine as inhibitors of factor xa | |
| EP1001764A4 (en) | Heterocyclic amides as cell adhesion inhibitors | |
| AP2005003199A0 (en) | Aminopyrimidines as sorbitol dehydrogenase inhibitors | |
| ZA95937B (en) | Sulfated alpha-glycolipid derivatives as cell adhesion inhibitors | |
| AU1463499A (en) | Substituted pyrrole derivatives as cell adhesion inhibitors | |
| AU8059598A (en) | Heterocyclic amide compounds as cell adhesion inhibitors | |
| HRP20010527B1 (en) | Derivatives of monosaccharides as cell adhesion inhibitors | |
| PL355099A1 (en) | Pyrrole derivatives as phosphodiesterase vii inhibitors | |
| PL355022A1 (en) | Imidazopyridine derivatives as phosphodiesterase vii inhibitors | |
| GB0017279D0 (en) | Amides as cell adhesion inhibitors | |
| IL147245A0 (en) | Substituted purine derivatives as inhibitors of cell adhesion | |
| HK1041270A1 (en) | 2,-3-o-isoproylidene derivatives of monosaccharides as cell adhesion inhibitors | |
| EP1389200A4 (en) | SUBSTITUTED N-ARYLSULFONYL-PROLINE DERIVATIVES AS POWERFUL INHIBITORS OF CELL ADHESION | |
| PL355020A1 (en) | Imidazole derivatives as phosphodiesterase vii inhibitors | |
| IL112734A0 (en) | Sulfated beta-glycolipid derivatives as cell adhesion inhibitors | |
| AU4021700A (en) | Methods of use of beta1-integrin inhibitors | |
| AU6002700A (en) | Heterocyclic derivatives as inhibitors of factor xa | |
| IL144273A0 (en) | 2,3-o-isopropylidene derivatives of monosaccharides as cell adhesion inhibitors | |
| GB9804400D0 (en) | Substituted pyrrole derivatives as cell adhesion inhibitors | |
| GB9727215D0 (en) | Substituted beta-alanine derivatives as cell adhesion inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |