HUP0204247A3 - Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity - Google Patents

Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Info

Publication number
HUP0204247A3
HUP0204247A3 HU0204247A HUP0204247A HUP0204247A3 HU P0204247 A3 HUP0204247 A3 HU P0204247A3 HU 0204247 A HU0204247 A HU 0204247A HU P0204247 A HUP0204247 A HU P0204247A HU P0204247 A3 HUP0204247 A3 HU P0204247A3
Authority
HU
Hungary
Prior art keywords
alkynylsubstituted
obesity
propionic acid
acid derivatives
use against
Prior art date
Application number
HU0204247A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of HUP0204247A2 publication Critical patent/HUP0204247A2/hu
Publication of HUP0204247A3 publication Critical patent/HUP0204247A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0204247A 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity HUP0204247A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000137 2000-01-28
DKPA200001065 2000-07-07
DKPA200001593 2000-10-25
PCT/DK2001/000057 WO2001055086A1 (en) 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Publications (2)

Publication Number Publication Date
HUP0204247A2 HUP0204247A2 (hu) 2003-04-28
HUP0204247A3 true HUP0204247A3 (en) 2003-10-28

Family

ID=27222337

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204247A HUP0204247A3 (en) 2000-01-28 2001-01-26 Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity

Country Status (13)

Country Link
EP (1) EP1254102A1 (hu)
JP (1) JP2003520839A (hu)
KR (1) KR20020090211A (hu)
CN (1) CN1396904A (hu)
AU (1) AU2831801A (hu)
BR (1) BR0107902A (hu)
CA (1) CA2396372A1 (hu)
HU (1) HUP0204247A3 (hu)
IL (1) IL150259A0 (hu)
MX (1) MXPA02007295A (hu)
NO (1) NO20023567L (hu)
PL (1) PL357017A1 (hu)
WO (1) WO2001055086A1 (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
JPWO2003016265A1 (ja) 2001-08-17 2004-12-02 エーザイ株式会社 環状化合物およびpparアゴニスト
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
HUP0401837A2 (hu) * 2001-10-17 2004-12-28 Novo Nordisk A/S Dikarbonsavszármazékok, előállításuk és gyógyászati alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
ITRM20020014A1 (it) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del
US7091245B2 (en) 2002-09-05 2006-08-15 Novo Novdisk A/S Compounds, their preparation and use
EP1745014B1 (en) 2004-05-05 2011-07-06 High Point Pharmaceuticals, LLC Novel compounds, their preparation and use
US20090042781A1 (en) * 2004-06-28 2009-02-12 Novo Nordisk A/S Methods for Treating Diabetes
BRPI0620468A2 (pt) 2005-12-22 2011-11-08 Transtech Pharma Inc ácidos fenóxi acéticos como ativadores de ppar delta
US10307480B2 (en) 2014-11-06 2019-06-04 Scholar Rock, Inc. Anti-pro/latent-myostatin antibodies and uses thereof
PL3350220T3 (pl) 2015-09-15 2022-01-03 Scholar Rock, Inc. Przeciwciała przeciwko pro/latentnej miostatynie i ich zastosowania
EP3400240A2 (en) 2016-01-08 2018-11-14 Scholar Rock, Inc. Anti-pro/latent myostatin antibodies and methods of use thereof
US11155611B2 (en) * 2017-01-06 2021-10-26 Scholar Rock, Inc. Compositions and methods for making and using anti-myostatin antibodies
BR112023001048A2 (pt) 2020-07-22 2023-04-04 Reneo Pharmaceuticals Inc Agonista de ppar-delta cristalino
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134686C1 (ru) * 1992-07-03 1999-08-20 Смитклайн Бичам П.Л.С. Гетероциклическое соединение, или его таутомерная форма, и/или фармацевтически приемлемая соль, и/или фармацевтически приемлемый сольват, фармацевтическая композиция, снижающая содержание глюкозы в крови, способ лечения и/или профилактики гипергликемии
FR2707989B1 (fr) * 1993-07-22 1995-10-13 Pf Medicament Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant.
BR9508468A (pt) * 1994-07-29 1997-11-25 Smithkline Beecham Plc Composto processo para a preparação do mesmo composição farmacéutica processos para o tratamento e/ou profilaxia de hiperglicemia em um mamifero humano ou não humano e para o tratamento de hiperlípidemia hipertensão doença cardiovascular alguns distúrbios de alimentação o tratamento e/ou profilaxia de doença renal a prevenção revers o estabilização ou retardo da progressão de microalbuminuria em um mamifero humano ou não humano uso do composto e composto intermediário
GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
GB9606805D0 (en) * 1996-03-30 1996-06-05 Glaxo Wellcome Inc Medicaments

Also Published As

Publication number Publication date
NO20023567L (no) 2002-09-25
WO2001055086A1 (en) 2001-08-02
MXPA02007295A (es) 2002-11-29
JP2003520839A (ja) 2003-07-08
IL150259A0 (en) 2002-12-01
CN1396904A (zh) 2003-02-12
BR0107902A (pt) 2002-11-05
PL357017A1 (en) 2004-07-12
AU2831801A (en) 2001-08-07
CA2396372A1 (en) 2001-08-02
NO20023567D0 (no) 2002-07-26
EP1254102A1 (en) 2002-11-06
HUP0204247A2 (hu) 2003-04-28
KR20020090211A (ko) 2002-11-30

Similar Documents

Publication Publication Date Title
IL150260A0 (en) Propionic acid derivatives and their use in the treatment of diabetes and obesity
AU2002225356A1 (en) Glucopyranosyloxypyrazole derivatives and use thereof in medicines
MXPA03005923A (es) Derivados de glupopiranosiloxipirazol y su uso en medicinas.
HUP0201633A3 (en) Alpha-aminosulphonyl-acetohydroxamic acid derivatives with metalloprotease inhibiting effect, preparation and use thereof
EP1367060A4 (en) GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND THEIR MEDICAL USE
EP1364957A4 (en) GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND THEIR MEDICAL USE
EP1364958A4 (en) GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND MEDICINAL USE THEREOF
IL149374A0 (en) New use and novel n-azabicyclo-amide derivatives
ZA200410054B (en) Propionic acid derivatives and their use as hPPARsactivators.
HUP0204247A3 (en) Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity
HUP0302306A3 (en) Propionic acid derivatives with ppar-alpha activating properties
HUP0201486A2 (en) Arylmalonic acid dinitrile derivatives, preparation and use thereof
AU2003255463A1 (en) Substituted isoxazole derivatives and their use in pharmaceutics
GB0023323D0 (en) Arylhydantoin derivatives and uses thereof
AU2001235437A1 (en) Isothiazolecarboxylic acid derivatives and their use as microbicides
AU2001261750A1 (en) Laminate and its use
AU2001286621A1 (en) Human transporter family members and uses thereof
ZA200204800B (en) Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity.
AU2002212176A1 (en) Substituted phenylcyclohexane carboxylic acid amides and the use thereof
ZA200204799B (en) Propionic acid derivatives and their use in the treatment of diabetes and obesity.
AU5974100A (en) 6-carboxyphenyldihydropyridazinone derivatives and use thereof
AU2001234180A1 (en) Benzamide derivative and use thereof
AU2002352281A1 (en) Device for delivering liquids for human consumption and other uses
AU6150400A (en) Tetrahydroquinolinyl-6-methyldihydrothiadiazinone derivatives and use thereof
AU2001282268A1 (en) Phenantridine derivatives and their use as anti-telomerase agent