FR2707989B1 - Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant. - Google Patents

Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant.

Info

Publication number
FR2707989B1
FR2707989B1 FR9309025A FR9309025A FR2707989B1 FR 2707989 B1 FR2707989 B1 FR 2707989B1 FR 9309025 A FR9309025 A FR 9309025A FR 9309025 A FR9309025 A FR 9309025A FR 2707989 B1 FR2707989 B1 FR 2707989B1
Authority
FR
France
Prior art keywords
salts
pharmaceutical compositions
compositions containing
manufacturing processes
benzylamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9309025A
Other languages
English (en)
Other versions
FR2707989A1 (fr
Inventor
Halazy Serge
Gotteland Jean-Pierre
Delhon Andre
Junquero Didier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR9309025A priority Critical patent/FR2707989B1/fr
Priority to PCT/FR1994/000921 priority patent/WO1995003313A1/fr
Priority to EP94922295A priority patent/EP0710241A1/fr
Priority to JP7504983A priority patent/JPH09500635A/ja
Priority to CA002167821A priority patent/CA2167821A1/fr
Priority to AU73467/94A priority patent/AU7346794A/en
Publication of FR2707989A1 publication Critical patent/FR2707989A1/fr
Application granted granted Critical
Publication of FR2707989B1 publication Critical patent/FR2707989B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FR9309025A 1993-07-22 1993-07-22 Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant. Expired - Fee Related FR2707989B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9309025A FR2707989B1 (fr) 1993-07-22 1993-07-22 Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant.
PCT/FR1994/000921 WO1995003313A1 (fr) 1993-07-22 1994-07-22 Nouveaux derives de benzylamines silylees, leurs sels, leurs procedes de fabrication et les compositions pharmaceutiques les renfermant
EP94922295A EP0710241A1 (fr) 1993-07-22 1994-07-22 Nouveaux derives de benzylamines silylees, leurs sels, leurs procedes de fabrication et les compositions pharmaceutiques les renfermant
JP7504983A JPH09500635A (ja) 1993-07-22 1994-07-22 新規なシリルベンジルアミン誘導体、その塩類、製法、およびそれを含む薬剤組成物
CA002167821A CA2167821A1 (fr) 1993-07-22 1994-07-22 Nouveaux derives de benzylamines silylees, leurs sels, leurs procedes de fabrication et les compositions pharmaceutiques les refermant
AU73467/94A AU7346794A (en) 1993-07-22 1994-07-22 Novel silylated benzylamine derivatives, salts thereof, methods of manufacture and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9309025A FR2707989B1 (fr) 1993-07-22 1993-07-22 Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant.

Publications (2)

Publication Number Publication Date
FR2707989A1 FR2707989A1 (fr) 1995-01-27
FR2707989B1 true FR2707989B1 (fr) 1995-10-13

Family

ID=9449506

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9309025A Expired - Fee Related FR2707989B1 (fr) 1993-07-22 1993-07-22 Nouveaux dérivés de benzylamines silylées, leurs sels, leurs procédés de fabrication et les compositions pharmaceutiques les renfermant.

Country Status (6)

Country Link
EP (1) EP0710241A1 (fr)
JP (1) JPH09500635A (fr)
AU (1) AU7346794A (fr)
CA (1) CA2167821A1 (fr)
FR (1) FR2707989B1 (fr)
WO (1) WO1995003313A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3824735B2 (ja) * 1997-05-13 2006-09-20 ポーラ化成工業株式会社 アミン誘導体
WO2000076523A1 (fr) * 1999-06-11 2000-12-21 Allergan Sales, Inc. Procedes de modulation de l'activite du recepteur fxr
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
CA2396372A1 (fr) * 2000-01-28 2001-08-02 Novo Nordisk A/S Derives d'acide propionique a substitution alkynyle et leur utilisation pour lutter contre le diabete et l'obesite
AU2002351752A1 (en) 2001-12-29 2003-07-30 Novo Nordisk A/S Combined use of a glp-1 compound and another drug for treating dyslipidemia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670421A (en) * 1982-07-12 1987-06-02 American Cyanamid Company Antiatherosclerotic silanes
NZ238807A (en) * 1990-07-05 1994-03-25 Merrell Dow Pharma Bis[4-(2,6-dialkyl)phenol]silane derivatives and antiatherosclerotic compositions
US5155250A (en) * 1990-07-05 1992-10-13 Merrell Dow Pharmaceuticals Inc. 2,6-di-alkyl-4-silyl-phenols as antiatheroscerotic agents

Also Published As

Publication number Publication date
JPH09500635A (ja) 1997-01-21
WO1995003313A1 (fr) 1995-02-02
EP0710241A1 (fr) 1996-05-08
CA2167821A1 (fr) 1995-02-02
FR2707989A1 (fr) 1995-01-27
AU7346794A (en) 1995-02-20

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Legal Events

Date Code Title Description
ST Notification of lapse