HUP0203582A2 - Polymorphic n-[3-{[2-(3,4-dimethoxyphenyl)ethyl]amino}propyl]-4-nitro benzamide hydrochloride, process for its preparation, pharmaceutical composition comprising thereof and its use - Google Patents
Polymorphic n-[3-{[2-(3,4-dimethoxyphenyl)ethyl]amino}propyl]-4-nitro benzamide hydrochloride, process for its preparation, pharmaceutical composition comprising thereof and its useInfo
- Publication number
- HUP0203582A2 HUP0203582A2 HU0203582A HUP0203582A HUP0203582A2 HU P0203582 A2 HUP0203582 A2 HU P0203582A2 HU 0203582 A HU0203582 A HU 0203582A HU P0203582 A HUP0203582 A HU P0203582A HU P0203582 A2 HUP0203582 A2 HU P0203582A2
- Authority
- HU
- Hungary
- Prior art keywords
- propyl
- ethyl
- amino
- dimethoxyphenyl
- polymorphic form
- Prior art date
Links
- QLUVAVFNMRXIIZ-UHFFFAOYSA-N n-[3-[2-(3,4-dimethoxyphenyl)ethylamino]propyl]-4-nitrobenzamide;hydrochloride Chemical compound Cl.C1=C(OC)C(OC)=CC=C1CCNCCCNC(=O)C1=CC=C([N+]([O-])=O)C=C1 QLUVAVFNMRXIIZ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 N-[3-{[2-(3,4-dimethoxyphenyl)ethyl]-amino}-propyl]-4-nitrobenzamide hydrochloride acetonitrile Chemical compound 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9923933.7A GB9923933D0 (en) | 1999-10-08 | 1999-10-08 | Novel pharmaceutical |
| PCT/GB2000/003847 WO2001027071A1 (en) | 1999-10-08 | 2000-10-06 | Polymorphic n-[3-[[2-(3,4-dimethoxyphenyl) ethyl] amino] propyl] -4-nitro benzamide hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0203582A2 true HUP0203582A2 (en) | 2004-03-01 |
Family
ID=10862442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203582A HUP0203582A2 (en) | 1999-10-08 | 2000-10-06 | Polymorphic n-[3-{[2-(3,4-dimethoxyphenyl)ethyl]amino}propyl]-4-nitro benzamide hydrochloride, process for its preparation, pharmaceutical composition comprising thereof and its use |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1218334A1 (zh) |
| JP (1) | JP2003511437A (zh) |
| KR (1) | KR20020043618A (zh) |
| CN (1) | CN1384817A (zh) |
| AU (1) | AU7546000A (zh) |
| BR (1) | BR0014591A (zh) |
| CA (1) | CA2386845A1 (zh) |
| CZ (1) | CZ20021189A3 (zh) |
| GB (1) | GB9923933D0 (zh) |
| HK (1) | HK1049147A1 (zh) |
| HU (1) | HUP0203582A2 (zh) |
| IL (1) | IL148966A0 (zh) |
| MX (1) | MXPA02003516A (zh) |
| NO (1) | NO20021639L (zh) |
| PL (1) | PL354137A1 (zh) |
| TR (1) | TR200200949T2 (zh) |
| WO (1) | WO2001027071A1 (zh) |
| ZA (1) | ZA200202679B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2272501B1 (en) * | 2002-01-09 | 2013-03-20 | Emisphere Technologies, Inc. | Polymorphs of sodium 4-((4-chloro-2-hydroxybenzoyl) amino) butanoate |
| PT2091910E (pt) * | 2006-12-06 | 2014-11-18 | Conatus Pharmaceuticals Inc | Formas cristalinas do ácido (3s)-3-[n-(n¿-(2-tercbutilfenil) oxamil)alaninil]amino-5-(2¿,3¿,5¿,6¿- tetrafluorofenoxi)-4-oxopentanóico |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2726267B1 (fr) * | 1994-10-26 | 1998-01-02 | Smithkline Beecham Lab | Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer |
| GB9706376D0 (en) * | 1997-03-27 | 1997-05-14 | Smithkline Beecham Plc | Novel pharmaceutical |
-
1999
- 1999-10-08 GB GBGB9923933.7A patent/GB9923933D0/en not_active Ceased
-
2000
- 2000-10-06 KR KR1020027004451A patent/KR20020043618A/ko not_active Application Discontinuation
- 2000-10-06 CA CA002386845A patent/CA2386845A1/en not_active Abandoned
- 2000-10-06 JP JP2001530092A patent/JP2003511437A/ja active Pending
- 2000-10-06 HU HU0203582A patent/HUP0203582A2/hu unknown
- 2000-10-06 CZ CZ20021189A patent/CZ20021189A3/cs unknown
- 2000-10-06 EP EP00964535A patent/EP1218334A1/en not_active Withdrawn
- 2000-10-06 AU AU75460/00A patent/AU7546000A/en not_active Abandoned
- 2000-10-06 CN CN00813990A patent/CN1384817A/zh active Pending
- 2000-10-06 BR BR0014591-2A patent/BR0014591A/pt not_active Application Discontinuation
- 2000-10-06 WO PCT/GB2000/003847 patent/WO2001027071A1/en active IP Right Grant
- 2000-10-06 IL IL14896600A patent/IL148966A0/xx unknown
- 2000-10-06 PL PL00354137A patent/PL354137A1/xx not_active Application Discontinuation
- 2000-10-06 TR TR2002/00949T patent/TR200200949T2/xx unknown
- 2000-10-06 MX MXPA02003516A patent/MXPA02003516A/es unknown
-
2002
- 2002-04-05 ZA ZA200202679A patent/ZA200202679B/en unknown
- 2002-04-05 NO NO20021639A patent/NO20021639L/no not_active Application Discontinuation
- 2002-12-27 HK HK02109370.9A patent/HK1049147A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL354137A1 (en) | 2003-12-29 |
| WO2001027071A1 (en) | 2001-04-19 |
| JP2003511437A (ja) | 2003-03-25 |
| EP1218334A1 (en) | 2002-07-03 |
| CA2386845A1 (en) | 2001-04-19 |
| CZ20021189A3 (cs) | 2002-09-11 |
| NO20021639L (no) | 2002-05-30 |
| MXPA02003516A (es) | 2004-09-10 |
| ZA200202679B (en) | 2003-05-28 |
| BR0014591A (pt) | 2002-06-11 |
| GB9923933D0 (en) | 1999-12-08 |
| CN1384817A (zh) | 2002-12-11 |
| IL148966A0 (en) | 2002-11-10 |
| NO20021639D0 (no) | 2002-04-05 |
| KR20020043618A (ko) | 2002-06-10 |
| HK1049147A1 (zh) | 2003-05-02 |
| TR200200949T2 (tr) | 2002-08-21 |
| AU7546000A (en) | 2001-04-23 |
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