HUP0105443A3 - Pharmaceutical compositions containing spisulosine compounds having antitumour activity - Google Patents
Pharmaceutical compositions containing spisulosine compounds having antitumour activityInfo
- Publication number
- HUP0105443A3 HUP0105443A3 HU0105443A HUP0105443A HUP0105443A3 HU P0105443 A3 HUP0105443 A3 HU P0105443A3 HU 0105443 A HU0105443 A HU 0105443A HU P0105443 A HUP0105443 A HU P0105443A HU P0105443 A3 HUP0105443 A3 HU P0105443A3
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- antitumour activity
- spisulosine
- compounds
- Prior art date
Links
- YRYJJIXWWQLGGV-ZWKOTPCHSA-N 1-deoxysphinganine Chemical class CCCCCCCCCCCCCCC[C@@H](O)[C@H](C)N YRYJJIXWWQLGGV-ZWKOTPCHSA-N 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Farming Of Fish And Shellfish (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/058,456 US6107520A (en) | 1997-04-15 | 1998-04-10 | Spisulosine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0105443A1 HUP0105443A1 (hu) | 2002-07-29 |
| HUP0105443A3 true HUP0105443A3 (en) | 2005-07-28 |
Family
ID=22016916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0105443A HUP0105443A3 (en) | 1998-04-10 | 1999-04-09 | Pharmaceutical compositions containing spisulosine compounds having antitumour activity |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6107520A (hu) |
| EP (1) | EP1069894B1 (hu) |
| JP (1) | JP2002511410A (hu) |
| KR (1) | KR100568964B1 (hu) |
| CN (1) | CN1335770A (hu) |
| AT (1) | ATE303139T1 (hu) |
| AU (1) | AU763981B2 (hu) |
| BG (1) | BG64970B1 (hu) |
| BR (1) | BR9910120A (hu) |
| CA (1) | CA2328126A1 (hu) |
| DE (1) | DE69927007T2 (hu) |
| DK (1) | DK1069894T3 (hu) |
| ES (1) | ES2248995T3 (hu) |
| HK (1) | HK1042048A1 (hu) |
| HU (1) | HUP0105443A3 (hu) |
| IL (1) | IL138886A0 (hu) |
| MX (1) | MXPA00009930A (hu) |
| NO (1) | NO20005052L (hu) |
| PL (1) | PL343381A1 (hu) |
| RU (1) | RU2225710C2 (hu) |
| SK (1) | SK15082000A3 (hu) |
| TR (1) | TR200002955T2 (hu) |
| UA (1) | UA72208C2 (hu) |
| WO (1) | WO1999052521A1 (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306911B1 (en) * | 2000-02-07 | 2001-10-23 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted amino acids as neutral sphingomyelinase inhibitors |
| BR0108448A (pt) * | 2000-02-16 | 2003-04-01 | Pharma Mar Sa | Derivados de tetraidrofuril óxi-e amino-substituìdos com atividade antitumor |
| CA2410409A1 (en) * | 2000-06-06 | 2001-12-13 | Pharma Mar, S.A. | Antitumoral compounds |
| FR2811556B1 (fr) * | 2000-07-11 | 2002-09-06 | Oreal | Composition comprenant un precurseur de ceramides, utilisation pour ameliorer l'epiderme naturel ou reconstruit , equivalent de peau obtenu |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| WO2004064713A2 (en) * | 2003-01-20 | 2004-08-05 | Vib Vzw | The use of yop preoteins or rho gtpase inhibitors as caspase-1 inhibitors |
| CN100360515C (zh) * | 2004-04-09 | 2008-01-09 | 中国科学院上海药物研究所 | 抗肿瘤活性成份陵水醇、制备方法和用途 |
| WO2006034849A1 (en) * | 2004-09-27 | 2006-04-06 | Pharma Mar, S.A., Sociedad Unipersonal | Antitumoral pharmaceutical compositions comprising a spisulosine and a cyclodextrin |
| JPWO2008156153A1 (ja) * | 2007-06-19 | 2010-08-26 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
| CN102206163B (zh) * | 2011-05-06 | 2013-07-10 | 中国海洋大学 | 一种长链碱的分离制备方法 |
| WO2014118556A2 (en) * | 2013-01-31 | 2014-08-07 | Research Foundation Of The City University Of New York | Selective inhibitors and allosteric activators of sphingosine kinase |
| CN104758275A (zh) * | 2015-03-05 | 2015-07-08 | 青岛申达高新技术开发有限公司 | 一种治疗结肠癌的药物组合物及其应用 |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
| CN112063606A (zh) * | 2020-08-25 | 2020-12-11 | 山东省科学院生物研究所 | 一种快速提取贝类消化内源酶的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816450A (en) * | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
| US5190876A (en) * | 1988-12-27 | 1993-03-02 | Emory University | Method of modifying cellular differentiation and function and compositions therefor |
| CA2007507C (en) * | 1989-02-03 | 1998-05-19 | Yasuyuki Igarashi | Sphingosine and n-methyl-sphingosine as inhibitor of cell growth |
| US5583160A (en) * | 1989-02-03 | 1996-12-10 | The Biomembrane Institute | Methylsphingosine used to treat apoptosis |
| US5426228A (en) * | 1994-06-27 | 1995-06-20 | Koskinen; Ari | General method for preparation of sphingosine bases and their analogues |
| EP0821068A3 (en) * | 1996-03-29 | 1999-06-02 | Rohm And Haas Company | Novel sphingolipids and a process thereto |
-
1998
- 1998-04-10 US US09/058,456 patent/US6107520A/en not_active Ceased
-
1999
- 1999-04-09 CN CN99807084A patent/CN1335770A/zh active Pending
- 1999-04-09 WO PCT/GB1999/001091 patent/WO1999052521A1/en active IP Right Grant
- 1999-04-09 MX MXPA00009930A patent/MXPA00009930A/es active IP Right Grant
- 1999-04-09 CA CA002328126A patent/CA2328126A1/en not_active Abandoned
- 1999-04-09 EP EP99915898A patent/EP1069894B1/en not_active Expired - Lifetime
- 1999-04-09 TR TR2000/02955T patent/TR200002955T2/xx unknown
- 1999-04-09 DK DK99915898T patent/DK1069894T3/da active
- 1999-04-09 AT AT99915898T patent/ATE303139T1/de not_active IP Right Cessation
- 1999-04-09 BR BR9910120-3A patent/BR9910120A/pt not_active Application Discontinuation
- 1999-04-09 HU HU0105443A patent/HUP0105443A3/hu unknown
- 1999-04-09 IL IL13888699A patent/IL138886A0/xx unknown
- 1999-04-09 KR KR1020007011292A patent/KR100568964B1/ko not_active IP Right Cessation
- 1999-04-09 RU RU2000128037/15A patent/RU2225710C2/ru not_active IP Right Cessation
- 1999-04-09 DE DE69927007T patent/DE69927007T2/de not_active Expired - Fee Related
- 1999-04-09 ES ES99915898T patent/ES2248995T3/es not_active Expired - Lifetime
- 1999-04-09 SK SK1508-2000A patent/SK15082000A3/sk unknown
- 1999-04-09 AU AU34321/99A patent/AU763981B2/en not_active Ceased
- 1999-04-09 JP JP2000543131A patent/JP2002511410A/ja not_active Abandoned
- 1999-04-09 PL PL99343381A patent/PL343381A1/xx not_active IP Right Cessation
- 1999-09-04 UA UA2000105675A patent/UA72208C2/uk unknown
-
2000
- 2000-10-06 NO NO20005052A patent/NO20005052L/no not_active Application Discontinuation
- 2000-11-09 BG BG104935A patent/BG64970B1/bg unknown
-
2002
- 2002-05-23 HK HK02103875.2A patent/HK1042048A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6107520A (en) | 2000-08-22 |
| EP1069894B1 (en) | 2005-08-31 |
| HUP0105443A1 (hu) | 2002-07-29 |
| SK15082000A3 (sk) | 2001-08-06 |
| NO20005052D0 (no) | 2000-10-06 |
| UA72208C2 (en) | 2005-02-15 |
| DE69927007T2 (de) | 2006-06-29 |
| JP2002511410A (ja) | 2002-04-16 |
| KR100568964B1 (ko) | 2006-04-07 |
| CA2328126A1 (en) | 1999-10-21 |
| MXPA00009930A (es) | 2002-04-24 |
| ES2248995T3 (es) | 2006-03-16 |
| WO1999052521A1 (en) | 1999-10-21 |
| DE69927007D1 (de) | 2005-10-06 |
| BR9910120A (pt) | 2000-12-26 |
| AU3432199A (en) | 1999-11-01 |
| EP1069894A1 (en) | 2001-01-24 |
| IL138886A0 (en) | 2001-11-25 |
| BG104935A (en) | 2001-07-31 |
| AU763981B2 (en) | 2003-08-07 |
| PL343381A1 (en) | 2001-08-13 |
| KR20010074483A (ko) | 2001-08-04 |
| ATE303139T1 (de) | 2005-09-15 |
| RU2225710C2 (ru) | 2004-03-20 |
| TR200002955T2 (tr) | 2001-01-22 |
| DK1069894T3 (da) | 2006-01-09 |
| CN1335770A (zh) | 2002-02-13 |
| NO20005052L (no) | 2000-12-07 |
| HK1042048A1 (zh) | 2002-08-02 |
| BG64970B1 (bg) | 2006-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |