HUP0105151A3 - Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes - Google Patents

Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes

Info

Publication number
HUP0105151A3
HUP0105151A3 HU0105151A HUP0105151A HUP0105151A3 HU P0105151 A3 HUP0105151 A3 HU P0105151A3 HU 0105151 A HU0105151 A HU 0105151A HU P0105151 A HUP0105151 A HU P0105151A HU P0105151 A3 HUP0105151 A3 HU P0105151A3
Authority
HU
Hungary
Prior art keywords
dioxolanes
amino
preparation
methyl ester
acid methyl
Prior art date
Application number
HU0105151A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HUP0105151A2 publication Critical patent/HUP0105151A2/hu
Publication of HUP0105151A3 publication Critical patent/HUP0105151A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
HU0105151A 1998-07-15 1999-06-01 Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes HUP0105151A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9294498P 1998-07-15 1998-07-15
PCT/US1999/014957 WO2000003981A2 (en) 1998-07-15 1999-07-01 Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes

Publications (2)

Publication Number Publication Date
HUP0105151A2 HUP0105151A2 (hu) 2002-04-29
HUP0105151A3 true HUP0105151A3 (en) 2004-11-29

Family

ID=22235899

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105151A HUP0105151A3 (en) 1998-07-15 1999-06-01 Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes

Country Status (9)

Country Link
US (3) US6166227A (hu)
EP (1) EP1121351A4 (hu)
JP (1) JP2002520389A (hu)
KR (1) KR20010071895A (hu)
AU (1) AU753189B2 (hu)
CA (1) CA2337194A1 (hu)
HU (1) HUP0105151A3 (hu)
IL (1) IL140861A (hu)
WO (1) WO2000003981A2 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162913A (en) * 1998-07-15 2000-12-19 Bristol-Myers Squibb Co. Preparation of [4S-(4α,7α,10aβ)]-4-amino-octahydro-5-oxo-7H-pyrido[2,1 -b] [1,3]thiazepine-7-carboxylic acid, methyl ester and salts thereof via novel disulfides
KR20010071895A (ko) * 1998-07-15 2001-07-31 스티븐 비. 데이비스 신규 디옥솔란을 통한 (s)-2-아미노-6,6-디메톡시헥산산메틸 에스테르의 제조 방법
FR2813054B1 (fr) * 2000-08-21 2002-11-15 Faure Bertrand Equipements Sa Systeme pour vehicule, comportant un dispositif de commande adapte pour faire fonctionner un actionneur selectivement en fonction d'une valeur mesuree par un dispositif de mesure dispose dans un siege
US6620600B2 (en) * 2000-09-15 2003-09-16 Bristol-Myers Squibb Co. Enzymatic resolution of aryl and thio-substituted acids
DE10155065A1 (de) * 2001-11-09 2003-05-22 Degussa Verfahren zur Kristallisation von Oxonorleucinacetal

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS596297B2 (ja) * 1977-11-09 1984-02-10 相互薬工株式会社 新規アミドオキシム誘導体
US4397677A (en) * 1979-11-29 1983-08-09 Velsicol Chemical Corporation Dioxolane substituted 2,6-dinitroanilines
DE3043252C2 (de) * 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
DE3043159C2 (de) * 1980-11-15 1982-12-09 Degussa Ag, 6000 Frankfurt Cyclische Acetale des Glutaminsäure-γ-semialdehyds, Verfahren zu deren Herstellung und ihre Verwendung
NL8403487A (nl) * 1984-11-15 1986-06-02 Stamicarbon Werkwijze voor de enzymatische scheiding van dl-alfa-aminozuuramides.
US4591601A (en) * 1985-04-12 1986-05-27 Mcneilab, Inc. Anticonvulsant dioxolane methane sulfamates
JPH02501531A (ja) * 1987-08-17 1990-05-31 ノヴオ―ノルデイスク アー/エス 有機化学品の製法
EP0383403A1 (en) * 1989-02-16 1990-08-22 Stamicarbon B.V. Process for preparation of organic chemicals
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5463051A (en) * 1993-09-27 1995-10-31 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5332826A (en) * 1993-10-13 1994-07-26 Eastman Kodak Company Process for preparing aminoacetonitriles in one vessel
JPH10295392A (ja) 1997-04-22 1998-11-10 Kanegafuchi Chem Ind Co Ltd L−アルリジンアセタールの製造方法
NL1007113C2 (nl) * 1997-09-25 1999-03-26 Dsm Nv Werkwijze voor de bereiding van optisch actieve 2-amino-omega- oxoalkaanzuurderivaten.
US6133002A (en) 1997-09-25 2000-10-17 Dsm N.V. Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives
JP3679231B2 (ja) * 1997-11-04 2005-08-03 第一化学薬品株式会社 光学活性α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタール
JPH11140076A (ja) * 1997-11-04 1999-05-25 Dai Ichi Pure Chem Co Ltd N−アシル−α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタール
US6340752B1 (en) * 1998-01-06 2002-01-22 Bristol-Myers Squibb Co. Deprotection and recrystallization processes
JP3638425B2 (ja) * 1998-01-29 2005-04-13 第一化学薬品株式会社 光学活性α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタールの製造方法
US6174711B1 (en) * 1998-07-05 2001-01-16 Mitsubishi Gas Chemical Company Method for producing L-allysine acetal
WO2000004179A1 (en) * 1998-07-15 2000-01-27 Bristol-Myers Squibb Company Stereoselective reductive amination of ketones
KR20010071895A (ko) * 1998-07-15 2001-07-31 스티븐 비. 데이비스 신규 디옥솔란을 통한 (s)-2-아미노-6,6-디메톡시헥산산메틸 에스테르의 제조 방법
HUP0104996A2 (hu) * 1998-09-03 2002-04-29 Bristol-Myers Squibb Co. Enzimes oxidatív dezaminálási eljárás

Also Published As

Publication number Publication date
US6248882B1 (en) 2001-06-19
WO2000003981A3 (en) 2000-09-28
IL140861A0 (en) 2002-02-10
HUP0105151A2 (hu) 2002-04-29
KR20010071895A (ko) 2001-07-31
AU4852899A (en) 2000-02-07
EP1121351A2 (en) 2001-08-08
IL140861A (en) 2004-06-01
WO2000003981A8 (en) 2001-06-28
US6329542B1 (en) 2001-12-11
JP2002520389A (ja) 2002-07-09
US6166227A (en) 2000-12-26
AU753189B2 (en) 2002-10-10
CA2337194A1 (en) 2000-01-27
WO2000003981A2 (en) 2000-01-27
EP1121351A4 (en) 2003-05-02

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