HUP0105151A3 - Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes - Google Patents
Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanesInfo
- Publication number
- HUP0105151A3 HUP0105151A3 HU0105151A HUP0105151A HUP0105151A3 HU P0105151 A3 HUP0105151 A3 HU P0105151A3 HU 0105151 A HU0105151 A HU 0105151A HU P0105151 A HUP0105151 A HU P0105151A HU P0105151 A3 HUP0105151 A3 HU P0105151A3
- Authority
- HU
- Hungary
- Prior art keywords
- dioxolanes
- amino
- preparation
- methyl ester
- acid methyl
- Prior art date
Links
- 150000004862 dioxolanes Chemical class 0.000 title 1
- GINSNWSGZOGOGB-ZETCQYMHSA-N methyl (2s)-2-amino-6,6-dimethoxyhexanoate Chemical compound COC(OC)CCC[C@H](N)C(=O)OC GINSNWSGZOGOGB-ZETCQYMHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9294498P | 1998-07-15 | 1998-07-15 | |
| PCT/US1999/014957 WO2000003981A2 (en) | 1998-07-15 | 1999-07-01 | Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0105151A2 HUP0105151A2 (hu) | 2002-04-29 |
| HUP0105151A3 true HUP0105151A3 (en) | 2004-11-29 |
Family
ID=22235899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0105151A HUP0105151A3 (en) | 1998-07-15 | 1999-06-01 | Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6166227A (hu) |
| EP (1) | EP1121351A4 (hu) |
| JP (1) | JP2002520389A (hu) |
| KR (1) | KR20010071895A (hu) |
| AU (1) | AU753189B2 (hu) |
| CA (1) | CA2337194A1 (hu) |
| HU (1) | HUP0105151A3 (hu) |
| IL (1) | IL140861A (hu) |
| WO (1) | WO2000003981A2 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6162913A (en) * | 1998-07-15 | 2000-12-19 | Bristol-Myers Squibb Co. | Preparation of [4S-(4α,7α,10aβ)]-4-amino-octahydro-5-oxo-7H-pyrido[2,1 -b] [1,3]thiazepine-7-carboxylic acid, methyl ester and salts thereof via novel disulfides |
| KR20010071895A (ko) * | 1998-07-15 | 2001-07-31 | 스티븐 비. 데이비스 | 신규 디옥솔란을 통한 (ｓ)-2-아미노-6,6-디메톡시헥산산메틸 에스테르의 제조 방법 |
| FR2813054B1 (fr) * | 2000-08-21 | 2002-11-15 | Faure Bertrand Equipements Sa | Systeme pour vehicule, comportant un dispositif de commande adapte pour faire fonctionner un actionneur selectivement en fonction d'une valeur mesuree par un dispositif de mesure dispose dans un siege |
| US6620600B2 (en) * | 2000-09-15 | 2003-09-16 | Bristol-Myers Squibb Co. | Enzymatic resolution of aryl and thio-substituted acids |
| DE10155065A1 (de) * | 2001-11-09 | 2003-05-22 | Degussa | Verfahren zur Kristallisation von Oxonorleucinacetal |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS596297B2 (ja) * | 1977-11-09 | 1984-02-10 | 相互薬工株式会社 | 新規アミドオキシム誘導体 |
| US4397677A (en) * | 1979-11-29 | 1983-08-09 | Velsicol Chemical Corporation | Dioxolane substituted 2,6-dinitroanilines |
| DE3043252C2 (de) * | 1980-11-15 | 1982-12-02 | Degussa Ag, 6000 Frankfurt | Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung |
| DE3043159C2 (de) * | 1980-11-15 | 1982-12-09 | Degussa Ag, 6000 Frankfurt | Cyclische Acetale des Glutaminsäure-γ-semialdehyds, Verfahren zu deren Herstellung und ihre Verwendung |
| NL8403487A (nl) * | 1984-11-15 | 1986-06-02 | Stamicarbon | Werkwijze voor de enzymatische scheiding van dl-alfa-aminozuuramides. |
| US4591601A (en) * | 1985-04-12 | 1986-05-27 | Mcneilab, Inc. | Anticonvulsant dioxolane methane sulfamates |
| JPH02501531A (ja) * | 1987-08-17 | 1990-05-31 | ノヴオ―ノルデイスク アー／エス | 有機化学品の製法 |
| EP0383403A1 (en) * | 1989-02-16 | 1990-08-22 | Stamicarbon B.V. | Process for preparation of organic chemicals |
| US5508272A (en) * | 1993-06-15 | 1996-04-16 | Bristol-Myers Squibb Company | Compounds containing a fused bicycle ring and processes therefor |
| US5463051A (en) * | 1993-09-27 | 1995-10-31 | Schering Corporation | Process for preparing benzazepine intermediates for the synthesis of D1 antagonists |
| US5332826A (en) * | 1993-10-13 | 1994-07-26 | Eastman Kodak Company | Process for preparing aminoacetonitriles in one vessel |
| JPH10295392A (ja) | 1997-04-22 | 1998-11-10 | Kanegafuchi Chem Ind Co Ltd | Ｌ−アルリジンアセタールの製造方法 |
| NL1007113C2 (nl) * | 1997-09-25 | 1999-03-26 | Dsm Nv | Werkwijze voor de bereiding van optisch actieve 2-amino-omega- oxoalkaanzuurderivaten. |
| US6133002A (en) | 1997-09-25 | 2000-10-17 | Dsm N.V. | Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives |
| JP3679231B2 (ja) * | 1997-11-04 | 2005-08-03 | 第一化学薬品株式会社 | 光学活性α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタール |
| JPH11140076A (ja) * | 1997-11-04 | 1999-05-25 | Dai Ichi Pure Chem Co Ltd | Ｎ−アシル−α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタール |
| US6340752B1 (en) * | 1998-01-06 | 2002-01-22 | Bristol-Myers Squibb Co. | Deprotection and recrystallization processes |
| JP3638425B2 (ja) * | 1998-01-29 | 2005-04-13 | 第一化学薬品株式会社 | 光学活性α−アミノアジピン酸−γ−セミアルデヒドエチレンアセタールの製造方法 |
| US6174711B1 (en) * | 1998-07-05 | 2001-01-16 | Mitsubishi Gas Chemical Company | Method for producing L-allysine acetal |
| WO2000004179A1 (en) * | 1998-07-15 | 2000-01-27 | Bristol-Myers Squibb Company | Stereoselective reductive amination of ketones |
| KR20010071895A (ko) * | 1998-07-15 | 2001-07-31 | 스티븐 비. 데이비스 | 신규 디옥솔란을 통한 (ｓ)-2-아미노-6,6-디메톡시헥산산메틸 에스테르의 제조 방법 |
| HUP0104996A2 (hu) * | 1998-09-03 | 2002-04-29 | Bristol-Myers Squibb Co. | Enzimes oxidatív dezaminálási eljárás |
-
1999
- 1999-06-01 KR KR1020017000563A patent/KR20010071895A/ko not_active Application Discontinuation
- 1999-06-01 IL IL14086199A patent/IL140861A/en not_active IP Right Cessation
- 1999-06-01 HU HU0105151A patent/HUP0105151A3/hu unknown
- 1999-07-01 CA CA002337194A patent/CA2337194A1/en not_active Abandoned
- 1999-07-01 JP JP2000560090A patent/JP2002520389A/ja active Pending
- 1999-07-01 AU AU48528/99A patent/AU753189B2/en not_active Ceased
- 1999-07-01 EP EP99932163A patent/EP1121351A4/en not_active Withdrawn
- 1999-07-01 WO PCT/US1999/014957 patent/WO2000003981A2/en not_active Application Discontinuation
- 1999-07-08 US US09/349,867 patent/US6166227A/en not_active Expired - Fee Related
-
2000
- 2000-10-12 US US09/689,209 patent/US6248882B1/en not_active Expired - Fee Related
- 2000-10-12 US US09/689,215 patent/US6329542B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6248882B1 (en) | 2001-06-19 |
| WO2000003981A3 (en) | 2000-09-28 |
| IL140861A0 (en) | 2002-02-10 |
| HUP0105151A2 (hu) | 2002-04-29 |
| KR20010071895A (ko) | 2001-07-31 |
| AU4852899A (en) | 2000-02-07 |
| EP1121351A2 (en) | 2001-08-08 |
| IL140861A (en) | 2004-06-01 |
| WO2000003981A8 (en) | 2001-06-28 |
| US6329542B1 (en) | 2001-12-11 |
| JP2002520389A (ja) | 2002-07-09 |
| US6166227A (en) | 2000-12-26 |
| AU753189B2 (en) | 2002-10-10 |
| CA2337194A1 (en) | 2000-01-27 |
| WO2000003981A2 (en) | 2000-01-27 |
| EP1121351A4 (en) | 2003-05-02 |
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