NO20012266L - Fremgangsmåte for fremstilling av L-DOPA-etylester - Google Patents

Fremgangsmåte for fremstilling av L-DOPA-etylester

Info

Publication number
NO20012266L
NO20012266L NO20012266A NO20012266A NO20012266L NO 20012266 L NO20012266 L NO 20012266L NO 20012266 A NO20012266 A NO 20012266A NO 20012266 A NO20012266 A NO 20012266A NO 20012266 L NO20012266 L NO 20012266L
Authority
NO
Norway
Prior art keywords
preparation
ethyl ester
dopa ethyl
dopa
ester
Prior art date
Application number
NO20012266A
Other languages
English (en)
Other versions
NO20012266D0 (no
Inventor
Ramy Lidor
Eliezer Bahar
Anton Frenkel
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of NO20012266D0 publication Critical patent/NO20012266D0/no
Publication of NO20012266L publication Critical patent/NO20012266L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20012266A 1998-11-10 2001-05-08 Fremgangsmåte for fremstilling av L-DOPA-etylester NO20012266L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10782098P 1998-11-10 1998-11-10
PCT/US1999/026548 WO2000027801A1 (en) 1998-11-10 1999-11-10 Process for manufacture of l-dopa ethyl ester

Publications (2)

Publication Number Publication Date
NO20012266D0 NO20012266D0 (no) 2001-05-08
NO20012266L true NO20012266L (no) 2001-06-26

Family

ID=22318659

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012266A NO20012266L (no) 1998-11-10 2001-05-08 Fremgangsmåte for fremstilling av L-DOPA-etylester

Country Status (13)

Country Link
US (2) US6218566B1 (no)
EP (1) EP1137626A4 (no)
JP (1) JP2002529443A (no)
CN (1) CN1325379A (no)
AU (1) AU764844B2 (no)
CA (1) CA2350303A1 (no)
HK (1) HK1041475A1 (no)
HU (1) HUP0103798A3 (no)
IL (1) IL143070A (no)
NO (1) NO20012266L (no)
NZ (1) NZ512030A (no)
WO (1) WO2000027801A1 (no)
ZA (1) ZA200103525B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746688B1 (en) 1996-10-13 2004-06-08 Neuroderm Ltd. Apparatus for the transdermal treatment of Parkinson's disease
IL159813A0 (en) * 2001-07-12 2004-06-20 Teva Pharma Dual release formulation comprising levodopa ethyl ester and a decarboxylase inhibitor in immediate release layer with levodopa ethyl ester and a decarboxylase inhibitor in a controlled release core
WO2003041646A2 (en) * 2001-11-13 2003-05-22 Teva Pharmaceutical Industries, Ltd. L-dopa ethyl ester salts and uses thereof
WO2003042136A2 (en) * 2001-11-13 2003-05-22 Teva Pharmaceutical Industries, Ltd. Process for the production of l-dopa ethyl ester
EP3291872A4 (en) 2015-05-06 2019-02-13 SynAgile Corporation PHARMACEUTICAL SUSPENSIONS WITH ACTIVE SUBSTANCES, DEVICES FOR THEIR ADMINISTRATION AND METHOD FOR THEIR USE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA716958B (en) 1970-10-30 1973-01-31 Hoffmann La Roche Phenylalanine amides
US3803120A (en) 1971-09-28 1974-04-09 Hoffmann La Roche Di-and tripeptides of 3-(3,4-dihydroxyphenyl)-alanine
US3939253A (en) 1973-11-02 1976-02-17 Interx Research Corporation Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease
JPS5157813A (en) 1974-11-14 1976-05-20 Sankyo Co Ll dooba mataha sonojudotaiseizaino seiho
US4035507A (en) 1975-04-17 1977-07-12 Interx Research Corporation Novel, transient pro-drug forms of L-DOPA to treat Parkinson's disease
US4916151A (en) 1985-12-05 1990-04-10 Merrell Dow Pharmaceuticals Inc. Method of treating parkinson's syndrome
US4663349A (en) 1985-12-30 1987-05-05 Merck & Co., Inc. Rectally absorbable form of L-dopa
US4771073A (en) 1985-12-30 1988-09-13 Merck & Co., Inc. Rectally absorbable form of L-dopa
ATE76747T1 (de) 1986-06-10 1992-06-15 Chiesi Farma Spa Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
US5354885A (en) 1992-12-24 1994-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Process for preparing ethyl ester of L-DOPA
US5607969A (en) 1992-12-24 1997-03-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem L-DOPA ethyl ester to treat Parkinson's disease

Also Published As

Publication number Publication date
AU1717000A (en) 2000-05-29
US6218566B1 (en) 2001-04-17
CA2350303A1 (en) 2000-05-18
IL143070A0 (en) 2002-04-21
ZA200103525B (en) 2002-05-02
NZ512030A (en) 2003-10-31
EP1137626A1 (en) 2001-10-04
US20020026069A1 (en) 2002-02-28
EP1137626A4 (en) 2002-07-17
HK1041475A1 (zh) 2002-07-12
CN1325379A (zh) 2001-12-05
HUP0103798A3 (en) 2002-12-28
WO2000027801A1 (en) 2000-05-18
IL143070A (en) 2004-03-28
AU764844B2 (en) 2003-09-04
NO20012266D0 (no) 2001-05-08
HUP0103798A2 (hu) 2002-02-28
JP2002529443A (ja) 2002-09-10

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