HUP0104431A2 - Finoman hangolt protegrinek - Google Patents

Finoman hangolt protegrinek

Info

Publication number
HUP0104431A2
HUP0104431A2 HU0104431A HUP0104431A HUP0104431A2 HU P0104431 A2 HUP0104431 A2 HU P0104431A2 HU 0104431 A HU0104431 A HU 0104431A HU P0104431 A HUP0104431 A HU P0104431A HU P0104431 A2 HUP0104431 A2 HU P0104431A2
Authority
HU
Hungary
Prior art keywords
peptides
protegrins
fine tuned
antimicrobial
aprotegrins
Prior art date
Application number
HU0104431A
Other languages
English (en)
Hungarian (hu)
Inventor
Conway C. Chang
Jie Chen
Chee Liang Gu
Robert I. Lehrer
Deborah A. Steinberg
Original Assignee
Intrabiotics Pharmaceuticals, Inc.
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrabiotics Pharmaceuticals, Inc., The Regents Of The University Of California filed Critical Intrabiotics Pharmaceuticals, Inc.
Publication of HUP0104431A2 publication Critical patent/HUP0104431A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Agronomy & Crop Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paints Or Removers (AREA)
HU0104431A 1995-11-22 1996-11-22 Finoman hangolt protegrinek HUP0104431A2 (hu)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56234695A 1995-11-22 1995-11-22
US64981196A 1996-05-17 1996-05-17
US69092196A 1996-08-01 1996-08-01
US08/752,852 US5994306A (en) 1995-11-22 1996-11-21 Fine-tuned protegrins
PCT/US1996/018544 WO1997018826A1 (en) 1995-11-22 1996-11-22 Fine tuned protegrins

Publications (1)

Publication Number Publication Date
HUP0104431A2 true HUP0104431A2 (hu) 2002-03-28

Family

ID=27415886

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104431A HUP0104431A2 (hu) 1995-11-22 1996-11-22 Finoman hangolt protegrinek

Country Status (12)

Country Link
US (1) US5994306A (enExample)
EP (1) EP0862448A4 (enExample)
JP (1) JP2001520639A (enExample)
KR (1) KR19990071546A (enExample)
CN (1) CN1251041A (enExample)
AU (1) AU720467B2 (enExample)
BR (1) BR9611565A (enExample)
CZ (1) CZ159198A3 (enExample)
HU (1) HUP0104431A2 (enExample)
NO (2) NO982311L (enExample)
PL (1) PL336763A1 (enExample)
WO (2) WO1997018826A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653442B1 (en) 1993-07-20 2003-11-25 Intrabiotics Pharmaceuticals, Inc. Protegrins
US6159936A (en) * 1993-07-20 2000-12-12 The Regents Of The University Of California Compositions and methods for treating and preventing microbial and viral infections
USRE38828E1 (en) * 1995-07-06 2005-10-11 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
US6307016B1 (en) * 1995-07-06 2001-10-23 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
FR2767323B1 (fr) * 1997-08-12 2001-01-05 Synt Em Peptides lineaires derives de peptides antibiotiques, leur preparation et leur utilisation pour vectoriser des substances actives
US6043220A (en) * 1997-12-03 2000-03-28 Intrabiotics Pharmaceuticals, Inc. Threonine-containing protegrins
KR100314721B1 (ko) * 1998-01-22 2001-11-23 김일웅 생물학적 활성이 있는 신규한 펩타이드
EP1129112B1 (en) * 1998-03-12 2006-10-25 Georgetown University Peptides containing a cholesterol recognition sequence and their uses
US7223727B2 (en) 1998-04-09 2007-05-29 Serono Genetics Institute S.A. GSSP4 polynucleotides and polypeptides and uses thereof
US20020102604A1 (en) 1999-12-08 2002-08-01 Milne Edwards Jean-Baptiste Dumas Full-length human cDNAs encoding potentially secreted proteins
ATE259654T1 (de) * 1998-06-26 2004-03-15 Nutricia Nv Pharmazeutische präparate zur bekämpfung oder prophylaxe von mikroorganismen infizierten oberflächen
EP0974360A3 (en) * 1998-06-26 2000-03-29 N.V. Nutricia Pharmaceutical preparations for use in combatting or preventing surface infections caused by microorganisms
WO2000001427A1 (en) * 1998-07-02 2000-01-13 Stichting Skeletal Tissue Engineering Group Amsterdam Bone cement with antimicrobial peptides
AU5006499A (en) * 1998-07-23 2000-02-14 Intrabiotics Pharmaceuticals, Inc. Compositions and methods for the treatment or prevention of pulmonary infections
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
EP1240180A2 (en) * 1999-12-21 2002-09-18 Innogenetics N.V. Peptides designed for the diagnosis and treatment of rheumatoid arthritis
BR0001870B1 (pt) * 2000-05-29 2014-02-25 Peptídeo, processo de obtenção de peptídeo, formulação compreendendo peptídeo, método de prevenção de crescimento de parasitas, fungos e bactérias, método para inativar a endotoxina de bactérias gram-negativas
GB0031425D0 (en) * 2000-12-22 2001-02-07 Amoebics Ltd Antibacterial treatments
KR100738362B1 (ko) * 2001-03-19 2007-07-12 재단법인서울대학교산학협력재단 신규한 디아민디티올 유도체 및 그의 방사성 레늄 또는방사성 테크네슘 착체； 그리고, 그의 방사성 레늄 착체와리피오돌을 포함하는 간암 치료용 조성물 및 그의 제조용키트
EP1401478A2 (en) * 2001-06-22 2004-03-31 The Hospital for Sick Children Antimicrobial peptides
US7033991B2 (en) * 2001-07-16 2006-04-25 Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College Inhibiting furin with polybasic peptides
WO2003062266A2 (en) * 2002-01-22 2003-07-31 Intrabiotics Pharmaceuticals, Inc. Hybrid synthetic method for antimicrobial peptides
JP4472998B2 (ja) 2002-04-22 2010-06-02 ダウ グローバル テクノロジーズ インコーポレイティド 低コストのペプチド製造
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
US20060148690A1 (en) * 2002-07-08 2006-07-06 Lydie Bougueleret Secreted peptides
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
US7875620B2 (en) * 2005-06-30 2011-01-25 Piper Medical, Inc. Methods of treating microbial infections
JP5775260B2 (ja) 2006-09-06 2015-09-09 シー３ ジアン インコーポレイテッド 選択的に標的化された抗菌性ペプチドおよびその使用
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
CA2727803C (en) 2008-05-13 2013-03-12 University Of Kansas Metal abstraction peptide (map) tag and associated methods
TWI394578B (zh) * 2009-01-09 2013-05-01 Academia Sinica 抗菌蛋白之新用途
US20100202983A1 (en) * 2009-02-09 2010-08-12 Jernberg Gary R Selectively targeted antimicrobials for the treatment of periodontal disease
MX2013013330A (es) 2011-05-16 2014-07-09 Cellceutix Corp Compuestos para utilizar en el tratamiento de mucositis.
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
US9925223B2 (en) 2012-09-25 2018-03-27 Regents Of The University Of Minnesota Methods for making and using antimicrobial peptides
CN103623391B (zh) * 2013-10-10 2014-12-31 中山大学 抗菌肽Protegrin-1在防治猪蓝耳病中的应用
US20160250298A1 (en) 2013-11-01 2016-09-01 Spherium Biomed S.L. Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents
CN103936827B (zh) * 2014-04-22 2015-10-14 福州大学 一种韭菜籽抗菌三肽及其制备方法与应用
CN105175509A (zh) * 2015-10-19 2015-12-23 河南科技学院 一种抗菌肽xyz-1及其应用
CN108524911B (zh) * 2018-02-27 2022-03-08 成都山信药业有限公司 Protegrin-1抗菌肽衍生物在制备抗口腔致病菌药物中的用途
AU2018445889B2 (en) * 2018-10-19 2025-09-25 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
WO2020139852A1 (en) 2018-12-28 2020-07-02 General Probiotics, Inc. Combinations of engineered antimicrobial probiotics for treatment of gastrointestinal tract pathogens
WO2021248008A1 (en) 2020-06-05 2021-12-09 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections
CN113975373A (zh) * 2021-11-18 2022-01-28 宁波市眼科医院 眼用制剂

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US4659692A (en) * 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4705777A (en) * 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US5087569A (en) * 1986-11-26 1992-02-11 Cornell Research Foundation, Inc. And The Rockefeller University Antimicrobial proteins, compositions containing same and uses thereof
US5338724A (en) * 1986-11-26 1994-08-16 Cornell Research Foundation, Inc. Antimicrobial proteins, compositions containing same and uses thereof
US5126257A (en) * 1986-11-26 1992-06-30 Cornell Research Foundation Antimicrobial proteins, compositions containing same and uses thereof
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5102870A (en) * 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
US5607916A (en) * 1989-07-05 1997-03-04 The Board Of Regents Of The University Of Oklahoma Method and composition for the treatment of septic shock
US5484885A (en) * 1989-07-05 1996-01-16 Emory University Chemotactic, antibiotic and lipopolysaccharide-binding peptide fragments of CAP37
US5447914A (en) * 1990-06-21 1995-09-05 Emory University Antimicrobial peptides
US5432270A (en) * 1990-10-25 1995-07-11 Zasloff; Michael A. DNA encoding tracheal antimicrobial peptides
JPH07502979A (ja) * 1991-07-25 1995-03-30 マゲイニン　ファーマス−ティカルズ，インコーポレーテッド 生物活性ペプチドを利用する口腔内の有害な状態の予防と治療
US5488035A (en) * 1991-12-06 1996-01-30 Pioneer Hi-Bred International, Inc. Peptide with inhibitory activity towards plant pathogenic fungi
EP0642348B1 (en) * 1992-05-26 2000-08-30 The Regents Of The University Of California Antibiotic cryptdin peptides and methods of their use
AU4682593A (en) * 1992-07-17 1994-02-14 Panorama Research, Inc. Mammalian cationic proteins having lipopolysaccharide binding and anti-coagulant activity
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
WO1994028921A1 (en) * 1993-06-04 1994-12-22 Demeter Biotechnologies, Ltd. Method of treating pulmonary disease states with non-naturally occurring amphipathic peptides
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5464823A (en) * 1993-07-20 1995-11-07 The Regents Of The University Of California Mammalian antibiotic peptides
JPH08504837A (ja) * 1993-10-14 1996-05-28 生化学工業株式会社 新規ポリペプチドおよびこれから調製される抗ｈｉｖ剤
US5804553A (en) * 1994-04-05 1998-09-08 University Of California Prophenins - antibiotic peptides
US5589364A (en) * 1994-07-29 1996-12-31 Magainin Pharmaceuticals Inc. Recombinant production of biologically active peptides and proteins
EP0836617A4 (en) * 1995-07-06 2000-06-28 Intrabiotics Pharmaceuticals PAREVINES AND TACHYTEGRINES

Also Published As

Publication number Publication date
AU720467B2 (en) 2000-06-01
KR19990071546A (ko) 1999-09-27
BR9611565A (pt) 1999-12-28
CN1251041A (zh) 2000-04-19
NO982311L (no) 1998-07-22
WO1997018827A1 (en) 1997-05-29
NO982311D0 (no) 1998-05-20
US5994306A (en) 1999-11-30
NO982310D0 (no) 1998-05-20
NO982310L (no) 1998-07-22
WO1997018826A1 (en) 1997-05-29
CZ159198A3 (cs) 1998-10-14
PL336763A1 (en) 2000-07-17
EP0862448A1 (en) 1998-09-09
EP0862448A4 (en) 1999-03-31
JP2001520639A (ja) 2001-10-30
AU7739496A (en) 1997-06-11

Similar Documents

Publication Publication Date Title
HUP0104431A2 (hu) Finoman hangolt protegrinek
DE69638294D1 (de) Schädlingsbekämpfungsmittel für Landwirtschaft und Gartenbau
DE69334186D1 (de) Vom MAGE-3-Gen en abgeleitetes und von HLA-A1 präsentiertes, isoliertes Nonapeptid und dessen Anwendungen
BG105868A (en) Pesticide and/or plant growth regulating compositions
ATE204328T1 (de) Biozide proteine
PT920421E (pt) Derivados de isoxazolina uteis como agentes antimicrobianos
IL122248A0 (en) Use of nisin for treating an infection
ATE253351T1 (de) Desodoriende zubereitungen enthaltend wasserlösliche -(1,3)-glucane
BR9402507A (pt) Espigadeira de cereais de colheitadeira
DE69835536D1 (de) Zusammensetzungen zur behandlung von staphylococcus aureus infektionen
DE59407001D1 (de) Federzinken, Fördervorrichtung und Erntemaschine
KR940008693A (ko) 포도상구균 항균제
TW352329B (en) Fungicidal mixtures
DE69206007D1 (de) Fungizide für den Acker- und Gartenbau.
CA2199941A1 (en) Synthetic antibiotics
DK0736096T3 (da) Antimikrobielle proteiner
FI97678B (fi) Biosidinen koostumus
EP0629346A3 (en) Pesticide mixtures.
EP0640333A3 (en) Aerosol formulation-promoting hair growth.
EP0929217A4 (en) SORDARINE DERIVATIVES
EP0811688A3 (en) Staphylococcus aureus RNase P
EP1007032A4 (en) 4-Cyano-4-DEFORMYLSORDARIZIN DERIVATIVES
HUP9901183A2 (hu) Készítmények és eljárások az orális mukozitisz megakadályozására és kezelésére
BG104258A (en) 4-cyano-4-deformylsordarin derivatives
BR9611904A (pt) Dioxidos de ditiazol