HUP0103411A3 - Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions containing the compounds and their preparation process - Google Patents

Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions containing the compounds and their preparation process

Info

Publication number
HUP0103411A3
HUP0103411A3 HU0103411A HUP0103411A HUP0103411A3 HU P0103411 A3 HUP0103411 A3 HU P0103411A3 HU 0103411 A HU0103411 A HU 0103411A HU P0103411 A HUP0103411 A HU P0103411A HU P0103411 A3 HUP0103411 A3 HU P0103411A3
Authority
HU
Hungary
Prior art keywords
dyslipidaemia
atherosclerosis
diabetes
treatment
compounds
Prior art date
Application number
HU0103411A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP0103411A2 publication Critical patent/HUP0103411A2/hu
Publication of HUP0103411A3 publication Critical patent/HUP0103411A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/081,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
HU0103411A 1998-07-17 1999-07-09 Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions containing the compounds and their preparation process HUP0103411A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9809164A FR2781222A1 (fr) 1998-07-17 1998-07-17 Composes cycliques utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procede de preparation
PCT/EP1999/004831 WO2000004011A1 (en) 1998-07-17 1999-07-09 Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions and preparation process

Publications (2)

Publication Number Publication Date
HUP0103411A2 HUP0103411A2 (hu) 2002-04-29
HUP0103411A3 true HUP0103411A3 (en) 2002-08-28

Family

ID=9528730

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103411A HUP0103411A3 (en) 1998-07-17 1999-07-09 Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions containing the compounds and their preparation process

Country Status (22)

Country Link
US (1) US6528538B1 (hu)
EP (1) EP1098893B1 (hu)
JP (1) JP2002520407A (hu)
KR (1) KR20010070966A (hu)
CN (1) CN1309655A (hu)
AT (1) ATE235485T1 (hu)
AU (1) AU753287B2 (hu)
BR (1) BR9912138A (hu)
CA (1) CA2337481A1 (hu)
DE (1) DE69906303T2 (hu)
DK (1) DK1098893T3 (hu)
ES (1) ES2192853T3 (hu)
FR (1) FR2781222A1 (hu)
HK (1) HK1039615A1 (hu)
HU (1) HUP0103411A3 (hu)
ID (1) ID27854A (hu)
NO (1) NO20010266D0 (hu)
PL (1) PL345397A1 (hu)
PT (1) PT1098893E (hu)
SK (1) SK482001A3 (hu)
WO (1) WO2000004011A1 (hu)
ZA (1) ZA200101303B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
JPWO2003016265A1 (ja) * 2001-08-17 2004-12-02 エーザイ株式会社 環状化合物およびpparアゴニスト
ES2563304T3 (es) * 2003-04-24 2016-03-14 Incyte Holdings Corporation Derivados azaespiro alcano como inhibidores de metaloproteasas
CA2555817A1 (en) * 2004-01-09 2005-08-25 Cadila Healthcare Limited 1 , 3 - dioxane derivatives and analogues thereof useful in the treatment of i.a. obesity and diabetes
EP1781633A1 (en) * 2004-08-20 2007-05-09 Cadila Healthcare Limited Novel antidiabetic compounds
CN100389112C (zh) * 2004-12-16 2008-05-21 中国石油化工股份有限公司 一类环状缩醛和缩酮化合物及其应用
WO2007099553A2 (en) * 2006-02-27 2007-09-07 Cadila Healthcare Limited 1,3-dioxane carboxylic acids
MX2008014560A (es) * 2006-05-18 2008-11-28 Wellstat Therapeutics Corp Compuestos para el tratamiento de trastornos metabolicos.
WO2007143600A2 (en) * 2006-06-05 2007-12-13 Incyte Corporation Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases
WO2016056031A1 (en) 2014-10-08 2016-04-14 Council Of Scientific & Industrial Research Novel diol compounds synthesis and its use for formal synthesis of (2r, 3 s)-3-hydroxypipecolic acid
US9637575B2 (en) * 2014-12-31 2017-05-02 W. R. Grace & Co. -Conn. Catalyst system, olefin polymerization catalyst components comprising at least an internal electron donor compound, and methods of making and using the same
CN114867702A (zh) * 2019-12-13 2022-08-05 罗地亚经营管理公司 苯衍生物的生产

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032536A (en) * 1976-07-22 1977-06-28 Janssen Pharmaceutica N.V. (1h-benzimidazol-2-yl)carbamates
US5179216A (en) * 1990-08-16 1993-01-12 American Home Products Corporation N,n', n'-trisubstituted-5-bisaminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-coa:cholesterol-acyl transferase
TW209868B (hu) * 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
DE19637840A1 (de) * 1996-09-17 1998-03-19 Henkel Kgaa Verwendung von geminalen Dialkoxyalkansäureestern zur Herstellung von desodorierenden Körperpflegemitteln

Also Published As

Publication number Publication date
DE69906303T2 (de) 2003-12-11
JP2002520407A (ja) 2002-07-09
DK1098893T3 (da) 2003-07-07
FR2781222A1 (fr) 2000-01-21
NO20010266L (no) 2001-01-16
HK1039615A1 (zh) 2002-05-03
SK482001A3 (en) 2001-09-11
BR9912138A (pt) 2001-04-10
DE69906303D1 (de) 2003-04-30
ID27854A (id) 2001-04-26
AU753287B2 (en) 2002-10-17
EP1098893B1 (en) 2003-03-26
WO2000004011A1 (en) 2000-01-27
ES2192853T3 (es) 2003-10-16
EP1098893A1 (en) 2001-05-16
ZA200101303B (en) 2002-05-15
PL345397A1 (en) 2001-12-17
AU5034799A (en) 2000-02-07
US6528538B1 (en) 2003-03-04
NO20010266D0 (no) 2001-01-16
CA2337481A1 (en) 2000-01-27
ATE235485T1 (de) 2003-04-15
CN1309655A (zh) 2001-08-22
PT1098893E (pt) 2003-08-29
KR20010070966A (ko) 2001-07-28
HUP0103411A2 (hu) 2002-04-29

Similar Documents

Publication Publication Date Title
HUP0302480A3 (en) Pyridinone derivatives for treatment of atherosclerosis, process for preparation thereof and pharmaceutical compositions containing the same
HUP0303078A3 (en) Cyclic peptidies process for their preparation pharmaceutical compositions containing them and their use
HUP0202338A3 (en) Pharmaceutical composition containing fenofibrate and preparation method
HUP0303398A3 (en) 1,2-dihydropyridine compounds, process for preparation of the same and use thereof and pharmaceutical compositions containing the same
HUP0203902A3 (en) Substituted oxazolidinones, process for their preparation and pharmaceutical compositions containing them and their use
HUP0300207A3 (en) 1,2,3,4-tetrahydroisquinoline derivatives, pharmaceutical compositions containing them and their preparation processes
IL144910A0 (en) Cyclic compounds and pharmaceutical compositions containing the same
HUP0203542A3 (en) 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
CZ20011652A3 (cs) Farmaceutický přípravek zahrnující moxifloxacin, způsob výroby a použití tohoto přípravku
HUP0204085A3 (en) New oxabispidine compounds useful in the treatment of cardiac arrhythmias, process for their preparation and pharmaceutical compositions containing them
HUP0203821A3 (en) Novel oligosaccharides, preparation method and pharmaceutical compositions containing same
HUP0105313A3 (en) Potassium salt of (s)-omeprazole, process for its preparation and pharmaceutical composition containing the same and its use
IL143858A (en) 4-(aminomethyl)-piperidine benzamides, process for their preparation and pharmaceutical compositions containing them
PL345354A1 (en) 2-aminopyridine erivatives, their use as medicines and pharmaceutical compositions containing them
HUP0303006A3 (en) Retinoids for the treatment of emphysema, process for their preparation and pharmaceutical compositions containing them
HUP0103411A3 (en) Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions containing the compounds and their preparation process
HK1039122A1 (zh) 取代的6-苄基-4-氧代嘧啶,其製備方法以及含該化合物的藥物組合物
HUP0105481A3 (en) Pharmaceutical compositions containing clarithromycin and process for their preparation and their use
HUP0001093A3 (en) Oxazolidines as 5-ht2a-antagonists, pharmaceutical compositions containing the same and process for their preparation
HUP0201785A3 (en) Dihydrobenzodiazepins, process for producing them, their use and pharmaceutical compositions containing them
HUP0103832A3 (en) Triazolopyridines for the treatment of thrombosis disorders, pharmaceutical compositions containing the same and process for preparation thereof
HUP0401325A3 (en) Isoxazolopyridinones useful in the treatment of parkinson's disease, process for their preparation and pharmaceutical compositions containing the compounds
HUP0301185A3 (en) Compounds for treating impaired fundic relaxation, process for their preparation and pharmaceutical compositions containing them
HK1029999A1 (en) New pentasaccharides, their methods of production and pharmaceutical compositions containing same
HUP0104834A3 (en) Sulphonyloxazolamines, their use, pharmaceutical compositions containing them and their preparation