HUP0102657A2 - Eljárás orto-alkilezett benzoesav-származékok, mint intermedierek és hatóanyagok előállítására - Google Patents

Eljárás orto-alkilezett benzoesav-származékok, mint intermedierek és hatóanyagok előállítására

Info

Publication number
HUP0102657A2
HUP0102657A2 HU0102657A HUP0102657A HUP0102657A2 HU P0102657 A2 HUP0102657 A2 HU P0102657A2 HU 0102657 A HU0102657 A HU 0102657A HU P0102657 A HUP0102657 A HU P0102657A HU P0102657 A2 HUP0102657 A2 HU P0102657A2
Authority
HU
Hungary
Prior art keywords
ortho
benzoic acid
acid derivatives
preparation
alkylated benzoic
Prior art date
Application number
HU0102657A
Other languages
English (en)
Inventor
Ekkehard Bartmann
Ingeborg Stein
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP0102657A2 publication Critical patent/HUP0102657A2/hu
Publication of HUP0102657A3 publication Critical patent/HUP0102657A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B18/00—Use of agglomerated or waste materials or refuse as fillers for mortars, concrete or artificial stone; Treatment of agglomerated or waste materials or refuse, specially adapted to enhance their filling properties in mortars, concrete or artificial stone
    • C04B18/02—Agglomerated materials, e.g. artificial aggregates
    • C04B18/021—Agglomerated materials, e.g. artificial aggregates agglomerated by a mineral binder, e.g. cement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
    • C04B2111/00767—Uses not provided for elsewhere in C04B2111/00 for waste stabilisation purposes
    • C04B2111/00775—Uses not provided for elsewhere in C04B2111/00 for waste stabilisation purposes the composition being used as waste barriers or the like, e.g. compositions used for waste disposal purposes only, but not containing the waste itself
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00—Technologies for solid waste management
    • Y02W30/50—Reuse, recycling or recovery technologies
    • Y02W30/91—Use of waste materials as fillers for mortars or concrete

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Civil Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A találmány tárgya eljárás (I) általános képletű orto-alkilezettbenzoesav-származékok előállítására, a képletben A jelentése 1-4szénatomos alkilcsoport, melynek során egy (II) általános képletűarilbromid-származékot szekunder vagy tercier szerves lítiumvegyülettel és CO2 reagenssel reagáltatnak. A találmány szerintelőállított orto-alkilezett benzoesav-származékok kiindulási anyagkéntalkalmazhatók finomkemikáliák, színezékek és növényvédő szereknagyipari előállításához, így a találmány további tárgyát képező N-diaminometilen-2-metil-4-(1-pirrolil)-5-metilszulfnil-benzamidelőállításához. Ó
HU0102657A 1998-07-23 1999-07-06 Method for the preparation of ortho-alkylated benzoic acid derivatives as intermediates and ingredients HUP0102657A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998133118 DE19833118C2 (de) 1998-07-23 1998-07-23 Verfahren zur Herstellung von orthoalkylierten Benzoesäurederivaten
PCT/EP1999/004674 WO2000005187A1 (de) 1998-07-23 1999-07-06 Verfahren zur herstellung von ortho-alkylierten benzoesäurederivaten

Publications (2)

Publication Number Publication Date
HUP0102657A2 true HUP0102657A2 (hu) 2001-11-28
HUP0102657A3 HUP0102657A3 (en) 2002-03-28

Family

ID=7875019

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102657A HUP0102657A3 (en) 1998-07-23 1999-07-06 Method for the preparation of ortho-alkylated benzoic acid derivatives as intermediates and ingredients

Country Status (23)

Country Link
US (3) US6350904B1 (hu)
EP (1) EP1098866B1 (hu)
JP (1) JP2002521352A (hu)
KR (1) KR20010053294A (hu)
CN (1) CN1190406C (hu)
AR (1) AR020620A1 (hu)
AT (1) ATE259343T1 (hu)
AU (1) AU756673B2 (hu)
BR (1) BR9912319A (hu)
CA (1) CA2338300A1 (hu)
DE (2) DE19833118C2 (hu)
DK (1) DK1098866T3 (hu)
ES (1) ES2216540T3 (hu)
HK (1) HK1039478A1 (hu)
HU (1) HUP0102657A3 (hu)
ID (1) ID27856A (hu)
NO (1) NO20010365L (hu)
PL (1) PL345284A1 (hu)
PT (1) PT1098866E (hu)
SK (1) SK852001A3 (hu)
TW (1) TW546285B (hu)
WO (1) WO2000005187A1 (hu)
ZA (1) ZA200101507B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7346623B2 (en) 2001-09-28 2008-03-18 Commvault Systems, Inc. System and method for generating and managing quick recovery volumes
AU2003279847A1 (en) 2002-10-07 2004-05-04 Commvault Systems, Inc. System and method for managing stored data
CA2544064C (en) 2003-11-13 2012-02-07 Commvault Systems, Inc. System and method for performing integrated storage operations
US8959299B2 (en) * 2004-11-15 2015-02-17 Commvault Systems, Inc. Using a snapshot as a data source
DE102005005946A1 (de) * 2005-02-10 2006-08-17 Basf Ag Verfahren zur Herstellung tertiärer Phosphine
US7928591B2 (en) * 2005-02-11 2011-04-19 Wintec Industries, Inc. Apparatus and method for predetermined component placement to a target platform
JP4641839B2 (ja) * 2005-03-23 2011-03-02 セントラル硝子株式会社 ４−メチル−３−トリフルオロメチル安息香酸の製造方法
US20100312013A1 (en) * 2009-06-03 2010-12-09 Boehringer Ingelheim International Gmbh Steroselective synthesis of certain trifluoromethyl-substituted alcohols
US8719767B2 (en) 2011-03-31 2014-05-06 Commvault Systems, Inc. Utilizing snapshots to provide builds to developer computing devices
US9092500B2 (en) 2009-09-03 2015-07-28 Commvault Systems, Inc. Utilizing snapshots for access to databases and other applications
US8595191B2 (en) * 2009-12-31 2013-11-26 Commvault Systems, Inc. Systems and methods for performing data management operations using snapshots
WO2011082132A1 (en) 2009-12-31 2011-07-07 Commvault Systems, Inc. Systems and methods for analyzing snapshots
WO2012166586A1 (en) * 2011-05-27 2012-12-06 Temple University - Of The Commonwealth System Of Higher Education SUBSTITUTED 2-BENZYLIDENE-2H-BENZO[b][1,4]THIAZIN-3(4H)-ONES, DERIVATIVES THEREOF, AND THERAPEUTIC USES THEREOF
CN106365978B (zh) * 2016-08-31 2019-01-11 绍兴上虞华伦化工有限公司 一种2,3-二氟-6-甲氧基苯甲酸的制备方法
CN115448831B (zh) * 2022-11-10 2023-02-03 北京元延医药科技股份有限公司 制备4-乙酰基-1-萘甲酸的方法
CN116425623B (zh) * 2023-04-10 2024-02-13 大连凯飞化学股份有限公司 一锅法合成3,5-二氯-4-甲基苯甲酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8613207D0 (en) * 1986-05-30 1986-07-02 Yarsley Technical Centre Ltd Trifluoromethyl aromatic compounds
ATE147375T1 (de) * 1992-09-22 1997-01-15 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika
DE4430213A1 (de) * 1994-08-28 1996-02-29 Merck Patent Gmbh Arylbenzoylguanidine
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE19529612A1 (de) 1995-08-11 1997-02-13 Merck Patent Gmbh Sulfonyl- oder Sulfinyl-benzoylguanidin-Derivate

Also Published As

Publication number Publication date
HUP0102657A3 (en) 2002-03-28
US6573404B2 (en) 2003-06-03
NO20010365D0 (no) 2001-01-22
AR020620A1 (es) 2002-05-22
PT1098866E (pt) 2004-06-30
CN1190406C (zh) 2005-02-23
KR20010053294A (ko) 2001-06-25
ZA200101507B (en) 2002-05-22
EP1098866A1 (de) 2001-05-16
AU756673B2 (en) 2003-01-23
CA2338300A1 (en) 2000-02-03
JP2002521352A (ja) 2002-07-16
EP1098866B1 (de) 2004-02-11
DE19833118C2 (de) 2000-07-27
ES2216540T3 (es) 2004-10-16
ID27856A (id) 2001-04-26
WO2000005187A1 (de) 2000-02-03
TW546285B (en) 2003-08-11
DE59908523D1 (de) 2004-03-18
US6350904B1 (en) 2002-02-26
HK1039478A1 (zh) 2002-04-26
AU5031499A (en) 2000-02-14
CN1310700A (zh) 2001-08-29
US20030069444A1 (en) 2003-04-10
DK1098866T3 (da) 2004-06-01
SK852001A3 (en) 2001-08-06
US6515143B2 (en) 2003-02-04
PL345284A1 (en) 2001-12-03
NO20010365L (no) 2001-01-22
DE19833118A1 (de) 2000-02-03
ATE259343T1 (de) 2004-02-15
US20020091286A1 (en) 2002-07-11
BR9912319A (pt) 2001-05-08

Similar Documents

Publication Publication Date Title
HUP0102657A2 (hu) Eljárás orto-alkilezett benzoesav-származékok, mint intermedierek és hatóanyagok előállítására
BG105457A (en) Method for the preparation of citalopram
ATE253581T1 (de) Verfahren zur herstellung von 3,4- alkylendioxythiophen-2,5-dicarbonsäurederivaten
DE69405864T2 (de) Verfahren zur Herstellung von quaternären Diestern
ES2000603A6 (es) Un procedimiento para preparar aril-piperidino carbinoles
ATE242241T1 (de) Imidazopyridinderivate und verfahren zu ihrer herstellung
NO20032731L (no) Fremgangsmåte for fremstilling av sulfonamid-substituerte imidazotriazinoner
EE200300090A (et) Asendatud imidasopüridiinühendite valmistamise meetod
MXPA02012398A (es) Proceso para la preparacion de derivados de quinolina.
ATE63109T1 (de) Verfahren zur herstellung von isothiazolonen.
LV10504A (lv) Mikrobiologiskais panemiens slapekli saturoso heterociklisko karbonskabju hidroksilesanai
NO173233C (no) Fremgangsmaate ved fremstilling av glutarsyrederivater, samt mellomprodukt for anvendelse ved utfoerelse av fremgangsmaaten
ATE259785T1 (de) Verfahren zur herstellung von 2-alkylthio- substituierten benzoesäurederivaten
AR005362A1 (es) Procedimiento para la preparacion de derivados de acido o-clorometil fenilglioxilico, compuestos e intermediarios de los mismos
BR0312773A (pt) Método para produzir um composto altamente puro
HUP9902967A2 (hu) Új eljárás trovafloxacinsav savaddíciós sóinak előállítására és intermedierek
HUP0401401A2 (hu) Eljárás 7-kinolinil-3,5-dihidroxi-hept-6-enoát előállítására
ATE67194T1 (de) Thiadiazolylacetamid-derivate, verfahren zu ihrer herstellung und ihre verwendung.
DE69819504D1 (de) Verfahren zur herstellung von 2-alkylthiobenzonitril-derivaten
ATE272618T1 (de) Verfahren zur herstellung von s-alkylcysteinen
TH40475A3 (th) กรรมวิธีสำหรับการเตรียมอนุพันธ์ ออร์โท-อัลคิเลทด์ เบนโซอิก แอซิด
FI863897A (fi) Kemiskt foerfarande.