HUP0102475A3 - Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same - Google Patents

Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same

Info

Publication number
HUP0102475A3
HUP0102475A3 HU0102475A HUP0102475A HUP0102475A3 HU P0102475 A3 HUP0102475 A3 HU P0102475A3 HU 0102475 A HU0102475 A HU 0102475A HU P0102475 A HUP0102475 A HU P0102475A HU P0102475 A3 HUP0102475 A3 HU P0102475A3
Authority
HU
Hungary
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
containing same
novel acyl
Prior art date
Application number
HU0102475A
Other languages
English (en)
Original Assignee
Om Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Om Pharma filed Critical Om Pharma
Publication of HUP0102475A2 publication Critical patent/HUP0102475A2/hu
Publication of HUP0102475A3 publication Critical patent/HUP0102475A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/10Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU0102475A 1998-06-30 1999-06-23 Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same HUP0102475A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801396 1998-06-30
PCT/IB1999/001170 WO2000000462A1 (fr) 1998-06-30 1999-06-23 Nouveaux pseudodipeptides acyles, leur mode de preparation et les compositions pharmaceutiques en renfermant

Publications (2)

Publication Number Publication Date
HUP0102475A2 HUP0102475A2 (hu) 2001-11-28
HUP0102475A3 true HUP0102475A3 (en) 2001-12-28

Family

ID=9522667

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102475A HUP0102475A3 (en) 1998-06-30 1999-06-23 Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same

Country Status (21)

Country Link
US (2) US7157092B1 (hu)
EP (1) EP1091928B1 (hu)
JP (1) JP4699609B2 (hu)
KR (1) KR100766016B1 (hu)
CN (1) CN1168702C (hu)
AR (1) AR029877A1 (hu)
AT (1) ATE355266T1 (hu)
AU (1) AU761396B2 (hu)
BR (1) BR9911329A (hu)
CA (1) CA2337807C (hu)
CZ (1) CZ302062B6 (hu)
DE (1) DE69935330T2 (hu)
DK (1) DK1091928T3 (hu)
EE (1) EE04489B1 (hu)
ES (1) ES2284275T3 (hu)
HU (1) HUP0102475A3 (hu)
PL (1) PL195764B1 (hu)
RU (1) RU2223262C2 (hu)
SK (1) SK287073B6 (hu)
TW (1) TWI255808B (hu)
WO (1) WO2000000462A1 (hu)

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ES2284275T3 (es) * 1998-06-30 2007-11-01 Om Pharma Nuevos pseudodipeptidos acilados, su procedimientos de preparacion y las composiciones farmaceuticas que los incluyen.
WO2001046127A1 (fr) * 1999-12-22 2001-06-28 Om Pharma Pseudodipeptides acyles porteurs d'un bras auxiliaire fonctionnalise
ATE446303T1 (de) * 2001-01-30 2009-11-15 Univ Virginia Agonisten und antagonisten von sphingosin-1- phosphatrezeptoren
DE60234375D1 (de) 2001-09-14 2009-12-24 Cytos Biotechnology Ag VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
US6932971B2 (en) 2002-07-18 2005-08-23 Cytos Biotechnology Ag Hapten-carrier conjugates and uses thereof
ZA200507063B (en) 2003-03-26 2007-03-28 Cytos Biotechnology Ag Packaging of immunostimulatory oligonucleotides into virus-like particles: Method of preparation and use
DE602005025342D1 (de) 2004-05-28 2011-01-27 Glaxosmithkline Biolog Sa Impfstoffzusammensetzungen mit virosomen und einem saponin-adjuvans
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US20070184068A1 (en) 2005-12-14 2007-08-09 Cytos Biotechnology Ag Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
CN101378778B (zh) 2005-12-22 2013-02-06 葛兰素史密丝克莱恩生物有限公司 肺炎球菌多糖缀合物疫苗
EP2051728A4 (en) * 2006-03-09 2010-03-31 Om Pharma IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF ILLNESSES DUE TO OVERPRODUCTION OF INFLAMMATORY CYTOKINS
EP2476433A1 (en) 2006-03-30 2012-07-18 GlaxoSmithKline Biologicals S.A. Immunogenic composition
ES2427994T3 (es) 2006-06-12 2013-11-05 Cytos Biotechnology Ag Procesos para empaquetar oligonucleótidos en partículas de tipo viral de bacteriófagos de ARN
PT2043682E (pt) 2006-07-17 2014-07-11 Glaxosmithkline Biolog Sa Vacina da influenza
NZ574239A (en) 2006-07-18 2011-12-22 Glaxosmithkline Biolog Sa Hybrid fusion proteins for malaria vaccines
WO2008012538A2 (en) 2006-07-25 2008-01-31 The Secretary Of State For Defence Live vaccine strains of francisella
EP2086582B1 (en) 2006-10-12 2012-11-14 GlaxoSmithKline Biologicals s.a. Vaccine comprising an oil in water emulsion adjuvant
SI2137210T1 (sl) 2007-03-02 2017-01-31 Glaxosmithkline Biologicals S.A. Nov postopek in sestavki
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EP2020240A1 (en) * 2007-07-30 2009-02-04 Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe Methods and substances for the treatment of Alzheimer's
AU2008352942B2 (en) 2007-12-19 2013-09-12 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Soluble forms of Hendra and Nipah virus F glycoprotein and uses thereof
SI2222710T1 (sl) 2007-12-24 2016-11-30 Id Biomedical Corporation Of Quebec Rekombinatni RSV antigeni
RS54306B1 (en) 2008-04-16 2016-02-29 Glaxosmithkline Biologicals S.A. THE VACCINE
CN102325790A (zh) 2008-12-03 2012-01-18 西马生物医学计划公司 应用酚可溶性调控蛋白研制疫苗
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GB0901423D0 (en) 2009-01-29 2009-03-11 Secr Defence Treatment
GB0901411D0 (en) 2009-01-29 2009-03-11 Secr Defence Treatment
EP2393922A1 (en) 2009-02-06 2011-12-14 GlaxoSmithKline Biologicals S.A. Purification of virus or viral antigens by density gradient ultracentrifugation
WO2010094663A1 (en) 2009-02-17 2010-08-26 Glaxosmithkline Biologicals S.A. Inactivated dengue virus vaccine with aluminium-free adjuvant
GB0906234D0 (en) 2009-04-14 2009-05-20 Secr Defence Vaccine
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GB0919117D0 (en) 2009-10-30 2009-12-16 Glaxosmithkline Biolog Sa Process
WO2011101332A1 (en) 2010-02-16 2011-08-25 Proyecto De Biomedicina Cima, S.L. Compositions based on the fibronectin extracellular domain a for the treatment of melanoma
ES2562818T3 (es) 2010-05-03 2016-03-08 Glaxosmithkline Biologicals S.A. Procedimiento de inactivación del virus de la gripe
GB201009273D0 (en) 2010-06-03 2010-07-21 Glaxosmithkline Biolog Sa Novel vaccine
AU2011315447A1 (en) 2010-10-15 2013-05-09 Glaxosmithkline Biologicals S.A. Cytomegalovirus gB antigen
EP2505640A1 (en) 2011-03-29 2012-10-03 Neo Virnatech, S.L. Vaccine compositions for birnavirus-borne diseases
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
WO2013139744A1 (en) 2012-03-18 2013-09-26 Glaxosmithkline Biologicals S.A. Method of vaccination against human papillomavirus
JP2015525794A (ja) 2012-08-06 2015-09-07 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 乳児においてrsv及び百日咳菌に対する免疫応答を惹起するための方法
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JPS61227586A (ja) * 1985-03-30 1986-10-09 Dai Ichi Seiyaku Co Ltd ジサツカライド誘導体およびその塩
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ES2284275T3 (es) * 1998-06-30 2007-11-01 Om Pharma Nuevos pseudodipeptidos acilados, su procedimientos de preparacion y las composiciones farmaceuticas que los incluyen.

Also Published As

Publication number Publication date
KR100766016B1 (ko) 2007-10-11
AU761396B2 (en) 2003-06-05
US20060148678A1 (en) 2006-07-06
US7157092B1 (en) 2007-01-02
EE04489B1 (et) 2005-06-15
CN1168702C (zh) 2004-09-29
EP1091928A1 (fr) 2001-04-18
AR029877A1 (es) 2003-07-23
KR20010083078A (ko) 2001-08-31
CZ20004893A3 (en) 2001-05-16
DK1091928T3 (da) 2007-07-23
ATE355266T1 (de) 2006-03-15
JP2002519338A (ja) 2002-07-02
HUP0102475A2 (hu) 2001-11-28
CA2337807A1 (fr) 2000-01-06
DE69935330T2 (de) 2007-10-31
PL345040A1 (en) 2001-11-19
WO2000000462A1 (fr) 2000-01-06
BR9911329A (pt) 2001-10-16
EP1091928B1 (fr) 2007-02-28
SK18872000A3 (sk) 2001-07-10
CA2337807C (fr) 2012-08-21
DE69935330D1 (de) 2007-04-12
CZ302062B6 (cs) 2010-09-22
SK287073B6 (sk) 2009-11-05
PL195764B1 (pl) 2007-10-31
TWI255808B (en) 2006-06-01
AU4284899A (en) 2000-01-17
CN1306504A (zh) 2001-08-01
EE200000791A (et) 2002-02-15
RU2223262C2 (ru) 2004-02-10
ES2284275T3 (es) 2007-11-01
JP4699609B2 (ja) 2011-06-15

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