HUP0102348A2 - Új eljárás szintézis-intermedierek előállítására - Google Patents

Új eljárás szintézis-intermedierek előállítására

Info

Publication number
HUP0102348A2
HUP0102348A2 HU0102348A HUP0102348A HUP0102348A2 HU P0102348 A2 HUP0102348 A2 HU P0102348A2 HU 0102348 A HU0102348 A HU 0102348A HU P0102348 A HUP0102348 A HU P0102348A HU P0102348 A2 HUP0102348 A2 HU P0102348A2
Authority
HU
Hungary
Prior art keywords
novel method
synthesis intermediates
preparing synthesis
enantiomeric
phenylalanine esters
Prior art date
Application number
HU0102348A
Other languages
English (en)
Inventor
Marie-Claude Bontoux
Olivier Favre-Bulle
Original Assignee
Aventis Cropscience S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Cropscience S.A. filed Critical Aventis Cropscience S.A.
Publication of HUP0102348A2 publication Critical patent/HUP0102348A2/hu
Publication of HUP0102348A3 publication Critical patent/HUP0102348A3/hu
Publication of HU228080B1 publication Critical patent/HU228080B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

A találmány tárgya eljárás az általános képletű, ahol Alk 1-6szénatomos egyenes vagy elágazó láncú alkilcsoport és enantiomermódosulat szempontjából lényegében tiszta a-fenil-alanin-észterekelőállítására az a-fenilalanin-észterek enantiomer-elegyének egylipázzal, egy proteázzal vagy egy észterázzal való érintkezésbehozásával. Ó
HU0102348A 1998-05-14 1999-05-10 Novel method for preparing synthesis intermediates HU228080B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9806339A FR2778671B1 (fr) 1998-05-14 1998-05-14 Nouveau procede de preparation d'intermediaires de synthese
PCT/FR1999/001098 WO1999058706A1 (fr) 1998-05-14 1999-05-10 Nouveau procede de preparation d'intermediaires de synthese

Publications (3)

Publication Number Publication Date
HUP0102348A2 true HUP0102348A2 (hu) 2001-10-28
HUP0102348A3 HUP0102348A3 (en) 2006-03-28
HU228080B1 HU228080B1 (en) 2012-10-29

Family

ID=9526525

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102348A HU228080B1 (en) 1998-05-14 1999-05-10 Novel method for preparing synthesis intermediates

Country Status (17)

Country Link
US (1) US6551816B1 (hu)
EP (1) EP1076718B1 (hu)
JP (1) JP4553485B2 (hu)
KR (1) KR100576276B1 (hu)
CN (1) CN1196795C (hu)
AT (1) ATE217025T1 (hu)
AU (1) AU3610299A (hu)
BR (1) BR9910677A (hu)
CA (1) CA2337269C (hu)
DE (1) DE69901388T2 (hu)
DK (1) DK1076718T3 (hu)
ES (1) ES2175966T3 (hu)
FR (1) FR2778671B1 (hu)
HU (1) HU228080B1 (hu)
IL (1) IL139600A0 (hu)
PT (1) PT1076718E (hu)
WO (1) WO1999058706A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759551B1 (en) 2000-11-03 2004-07-06 Bayer Cropscience S.A. Chiral (s- or r-methylphenylglycine) amino acid crystal and method for preparing same
EP1483283A4 (en) 2002-03-13 2007-04-11 Signum Biosciences Inc MODULATION OF PROTEIN METHYLATION AND PHOSPHOPROTEIN PHOSPHATE
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US8221804B2 (en) * 2005-02-03 2012-07-17 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
JP2008260755A (ja) * 2007-03-20 2008-10-30 Sumitomo Chemical Co Ltd Ｌ−ビフェニルアラニン化合物の塩の回収方法、およびそれを用いたビフェニルアラニンエステル化合物の回収方法
EP2282735B1 (en) 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes
CN101555211B (zh) * 2009-05-13 2012-01-25 浙江九洲药业股份有限公司 2-酰基氨基-3-联苯基丙酸的化学合成方法
CN102321690B (zh) * 2011-07-27 2012-07-18 陆宏国 一种酯类手性胺化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
FR2706456B1 (fr) * 1993-06-18 1996-06-28 Rhone Poulenc Agrochimie Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides.
US5552318A (en) * 1995-05-26 1996-09-03 Industrial Technology Research Institute Method for preparing optically active amino acids and their esters using wheat germ lipase
US5552317A (en) * 1995-05-26 1996-09-03 Industrial Technology Research Institute Method for preparing optically active homophenylalanine and esters thereof using lipase from wheat germ or Candida lipolytica
FR2751327A1 (fr) * 1996-07-22 1998-01-23 Rhone Poulenc Agrochimie Intermediaires pour la preparation de 2-imidazoline-5-ones

Also Published As

Publication number Publication date
EP1076718A1 (fr) 2001-02-21
DK1076718T3 (da) 2002-08-12
FR2778671B1 (fr) 2002-07-05
ES2175966T3 (es) 2002-11-16
ATE217025T1 (de) 2002-05-15
JP4553485B2 (ja) 2010-09-29
WO1999058706A1 (fr) 1999-11-18
CN1348500A (zh) 2002-05-08
IL139600A0 (en) 2002-02-10
CA2337269C (fr) 2007-04-10
BR9910677A (pt) 2001-11-20
CA2337269A1 (fr) 1999-11-18
US6551816B1 (en) 2003-04-22
FR2778671A1 (fr) 1999-11-19
CN1196795C (zh) 2005-04-13
AU3610299A (en) 1999-11-29
HUP0102348A3 (en) 2006-03-28
PT1076718E (pt) 2002-09-30
DE69901388T2 (de) 2002-08-29
JP2002514436A (ja) 2002-05-21
KR100576276B1 (ko) 2006-05-04
EP1076718B1 (fr) 2002-05-02
HU228080B1 (en) 2012-10-29
DE69901388D1 (de) 2002-06-06
KR20010025022A (ko) 2001-03-26

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Legal Events

Date Code Title Description
FH91 Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): BELICZAY LASZLO, S.B.G. & K. BUDAPESTI NEMZETKOEZI SZABADALMI IRODA, HU

Representative=s name: DR.LANG TIVADARNE S.B.G.& K.SZABADALMI UEGYVIV, HU