HUP0102206A2 - Delavirdint tartalmazó tabletta formájú készítmény - Google Patents
Delavirdint tartalmazó tabletta formájú készítményInfo
- Publication number
- HUP0102206A2 HUP0102206A2 HU0102206A HUP0102206A HUP0102206A2 HU P0102206 A2 HUP0102206 A2 HU P0102206A2 HU 0102206 A HU0102206 A HU 0102206A HU P0102206 A HUP0102206 A HU P0102206A HU P0102206 A2 HUP0102206 A2 HU P0102206A2
- Authority
- HU
- Hungary
- Prior art keywords
- tablet formulation
- delavirdine
- superdisintegrant
- binder
- microcrystalline cellulose
- Prior art date
Links
- 239000007916 tablet composition Substances 0.000 title abstract 2
- WHBIGIKBNXZKFE-UHFFFAOYSA-N delavirdine Chemical compound CC(C)NC1=CC=CN=C1N1CCN(C(=O)C=2NC3=CC=C(NS(C)(=O)=O)C=C3C=2)CC1 WHBIGIKBNXZKFE-UHFFFAOYSA-N 0.000 title 2
- 229960005319 delavirdine Drugs 0.000 title 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 2
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 2
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A találmány nem nyújtott felszabadulású gyógyászatitablettakészítményre vonatkozik, amely egy gyorsan kicsapódóhatóanyagot tartalmaz körülbelül 5% és körülbelül 60% közöttimennyiségben, mikrokristályos cellulóz és legalább egy kötőanyagottartalmaz körülbelül 2% és körülbelül 25% közötti mennyiségben, és egyszuperdiszintegránst körülbelül 6% és körülbelül 40% közöttimennyiségben, ahol a gyorsan kicsapódó hatóanyag, a mikrokristályoscellulóz, amelyben a kötőanyagot és a szuperdiszintegránst hevítés,oldószer és őrlés alkalmazása nélkül keverik össze és préseliktablettává. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8896098P | 1998-06-11 | 1998-06-11 | |
PCT/US1999/011798 WO1999063970A1 (en) | 1998-06-11 | 1999-06-07 | Delavirdine tablet formulation |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0102206A2 true HUP0102206A2 (hu) | 2002-03-28 |
HUP0102206A3 HUP0102206A3 (en) | 2002-12-28 |
Family
ID=22214517
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102206A HUP0102206A3 (en) | 1998-06-11 | 1999-06-07 | Delavirdine tablet formulation |
Country Status (21)
Country | Link |
---|---|
US (3) | US6177101B1 (hu) |
EP (1) | EP1083885B1 (hu) |
JP (1) | JP4827296B2 (hu) |
KR (2) | KR100724016B1 (hu) |
CN (1) | CN1237958C (hu) |
AT (1) | ATE349203T1 (hu) |
AU (1) | AU753241C (hu) |
BR (1) | BR9910481A (hu) |
CA (1) | CA2328703C (hu) |
CY (1) | CY1105924T1 (hu) |
DE (1) | DE69934582T2 (hu) |
DK (1) | DK1083885T3 (hu) |
EA (1) | EA004311B1 (hu) |
ES (1) | ES2277682T3 (hu) |
HK (1) | HK1036417A1 (hu) |
HU (1) | HUP0102206A3 (hu) |
NZ (1) | NZ508762A (hu) |
PL (1) | PL200163B1 (hu) |
PT (1) | PT1083885E (hu) |
WO (1) | WO1999063970A1 (hu) |
ZA (1) | ZA200006090B (hu) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9910481A (pt) * | 1998-06-11 | 2001-01-09 | Upjohn Co | Composição farmacêutica para comprimido de liberação não-contìnua |
AP2002002552A0 (en) | 1999-12-23 | 2002-06-30 | Pfizer Prod Inc | Pharmaceutical compositions providing enhanced drug concentrations. |
US7115279B2 (en) | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
US20040243118A1 (en) * | 2001-06-01 | 2004-12-02 | Ayers Gregory M. | Device and method for positioning a catheter tip for creating a cryogenic lesion |
CA2458644A1 (en) * | 2001-08-28 | 2003-03-13 | Pharmacia Corporation | Crystaline clindamycin free base |
DE10164510A1 (de) * | 2001-12-20 | 2003-07-10 | Schering Ag | Orale Fludara reinst Formulierung mit schneller Freisetzung des Wirkstoffes |
JP2004107258A (ja) * | 2002-09-18 | 2004-04-08 | Ss Pharmaceut Co Ltd | 催眠用圧縮成型製剤 |
WO2004066981A1 (en) * | 2003-01-29 | 2004-08-12 | Sun Pharmaceutical Industries Limited | Oral controlled release pharmaceutical composition containing metaxalone as active agent |
CA2520321A1 (en) * | 2003-04-04 | 2004-10-14 | Pharmacia Corporation | Oral extended release compressed tablets of multiparticulates |
EP1635847B1 (en) | 2003-06-13 | 2019-07-31 | IDH Holding ApS | Treatment of symptoms associated with bacterial vaginosis |
MXPA06000178A (es) * | 2003-07-01 | 2006-04-11 | Pharmacia & Upjohn Co Llc | Solidos modulados en la fase de difusion. |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
US20050283146A1 (en) * | 2004-06-17 | 2005-12-22 | Lentz David J | Thermally extended spiral cryotip for a cryoablation catheter |
US20060099253A1 (en) * | 2004-10-20 | 2006-05-11 | Wyeth | Antibiotic product formulation |
US20070059359A1 (en) * | 2005-06-07 | 2007-03-15 | Thomas Backensfeld | Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)[4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof |
WO2008012991A1 (fr) | 2006-07-27 | 2008-01-31 | Kabushiki Kaisha Kobe Seiko Sho | Dispositif de connexion et installation de malaxage possédant un dispositif de malaxage et un dispositif d'entraînement connectés l'un à l'autre par le dispositif de connexion |
CA2617688C (en) * | 2007-02-22 | 2015-08-18 | Alpex Pharma S.A. | Solid dosage formulations containing weight-loss drugs |
US8696606B2 (en) * | 2009-09-28 | 2014-04-15 | Continuous MotionFlow, LLC | Passive motion machine with integrated mechanical DVT prophylactic therapy |
WO2011041414A1 (en) | 2009-09-30 | 2011-04-07 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
JP5226732B2 (ja) * | 2010-05-20 | 2013-07-03 | エスエス製薬株式会社 | 催眠用圧縮成型製剤 |
US20120010216A1 (en) * | 2010-07-06 | 2012-01-12 | Brown Arthur M | Pharmaceutical compositions containing vanoxerine |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
CA2888883A1 (en) | 2012-10-18 | 2014-04-24 | Abbvie Inc. | Formulations of pyrimidinedione derivative compounds |
CN107595793B (zh) | 2012-11-30 | 2020-11-13 | 阿库拉制药公司 | 活性药物成分的自调节释放 |
LT3007695T (lt) | 2013-06-13 | 2024-03-25 | Akebia Therapeutics, Inc. | Kompozicijos ir būdai, skirti anemijos gydymui |
EP3089757A1 (en) | 2014-01-03 | 2016-11-09 | AbbVie Inc. | Solid antiviral dosage forms |
WO2017040607A1 (en) | 2015-08-31 | 2017-03-09 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
CA3097594A1 (en) * | 2018-05-15 | 2019-11-21 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Pharmaceutical composition comprising small molecule egfr inhibitor and preparation method therefor |
CN108619104A (zh) * | 2018-06-29 | 2018-10-09 | 哈尔滨珍宝制药有限公司 | 一种基于盐酸克林霉素的药物组合物及其制备方法 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4013785A (en) * | 1975-03-21 | 1977-03-22 | Bristol-Myers Company | Apap tablet containing fumed silica and process for manufacturing same |
ZA855250B (en) * | 1984-08-17 | 1986-02-26 | Upjohn Co | Stable,high dose,high bulk density ibuprofen granulations for tablet and capsule manufacturing |
GB8521350D0 (en) * | 1985-08-28 | 1985-10-02 | Euro Celtique Sa | Analgesic composition |
DE3708916A1 (de) | 1987-03-19 | 1988-09-29 | Boehringer Ingelheim Kg | Verfahren zur reinigung resorbierbarer polyester |
US5211958A (en) * | 1987-11-30 | 1993-05-18 | Gist-Brocades, N.V. | Pharmaceutical composition and process for its preparation |
ES2047540T3 (es) * | 1987-11-30 | 1994-03-01 | Brocades Pharma Bv | Compuesto farmaceutico y procedimiento para su preparacion. |
US5256699A (en) * | 1988-10-18 | 1993-10-26 | Ciba-Geify Corporation | Dispersible tablet formulation of diclofenac acid free base |
GB8824392D0 (en) * | 1988-10-18 | 1988-11-23 | Ciba Geigy Ag | Dispersible formulation |
CA2007764C (en) | 1989-02-24 | 1999-11-30 | Joseph Michael Beaurline | Salsalate tablet |
GB8909793D0 (en) * | 1989-04-28 | 1989-06-14 | Beecham Group Plc | Pharmaceutical formulation |
CA2031803C (en) | 1989-12-13 | 2001-05-29 | Ramakrishnan Nagarajan | Improvements in or relating to glycopeptide deriveratives |
US5563142A (en) * | 1989-12-28 | 1996-10-08 | The Upjohn Company | Diaromatic substituted compounds as anti-HIV-1 agents |
US5519021A (en) * | 1992-08-07 | 1996-05-21 | Merck & Co., Inc. | Benzoxazinones as inhibitors of HIV reverse transcriptase |
US5358941A (en) | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
FR2711524B1 (fr) * | 1993-10-21 | 1995-11-24 | Rhone Dpc Europ | Procédé de préparation de compositions orales contenant des quinolones. |
MX9604831A (es) | 1994-04-15 | 1998-05-31 | Upjohn Co | Formas nuevas de cristal de 1-[5-metanosulfonamidoindolil-2-carbonil]-4-[3-(1-metiletila mino)-2-piridinil]-piperazina. |
US5585115A (en) * | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
US5837292A (en) * | 1996-07-03 | 1998-11-17 | Yamanouchi Europe B.V. | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug |
US6013280A (en) * | 1997-10-07 | 2000-01-11 | Fuisz Technologies Ltd. | Immediate release dosage forms containing microspheres |
US5955107A (en) * | 1997-12-12 | 1999-09-21 | Fmc Corporation | Pharmaceutical suspension tablet compositions |
UA72207C2 (uk) * | 1998-04-07 | 2005-02-15 | Брістол- Майєрс Сквібб Фарма Компані | Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення |
BR9910481A (pt) * | 1998-06-11 | 2001-01-09 | Upjohn Co | Composição farmacêutica para comprimido de liberação não-contìnua |
-
1999
- 1999-06-07 BR BR9910481-4A patent/BR9910481A/pt not_active Application Discontinuation
- 1999-06-07 CN CNB998062316A patent/CN1237958C/zh not_active Expired - Lifetime
- 1999-06-07 CA CA002328703A patent/CA2328703C/en not_active Expired - Lifetime
- 1999-06-07 KR KR1020007013985A patent/KR100724016B1/ko not_active IP Right Cessation
- 1999-06-07 EA EA200100024A patent/EA004311B1/ru not_active IP Right Cessation
- 1999-06-07 AU AU42134/99A patent/AU753241C/en not_active Expired
- 1999-06-07 ES ES99925951T patent/ES2277682T3/es not_active Expired - Lifetime
- 1999-06-07 KR KR1020077007572A patent/KR20070040426A/ko not_active Application Discontinuation
- 1999-06-07 NZ NZ508762A patent/NZ508762A/en not_active IP Right Cessation
- 1999-06-07 WO PCT/US1999/011798 patent/WO1999063970A1/en not_active Application Discontinuation
- 1999-06-07 AT AT99925951T patent/ATE349203T1/de active
- 1999-06-07 PL PL344328A patent/PL200163B1/pl unknown
- 1999-06-07 JP JP2000553039A patent/JP4827296B2/ja not_active Expired - Lifetime
- 1999-06-07 DE DE69934582T patent/DE69934582T2/de not_active Revoked
- 1999-06-07 PT PT99925951T patent/PT1083885E/pt unknown
- 1999-06-07 HU HU0102206A patent/HUP0102206A3/hu unknown
- 1999-06-07 EP EP99925951A patent/EP1083885B1/en not_active Revoked
- 1999-06-07 US US09/327,135 patent/US6177101B1/en not_active Expired - Lifetime
- 1999-06-07 DK DK99925951T patent/DK1083885T3/da active
-
2000
- 2000-09-06 US US09/656,364 patent/US7108864B1/en not_active Expired - Lifetime
- 2000-10-27 ZA ZA200006090A patent/ZA200006090B/xx unknown
-
2001
- 2001-10-29 HK HK01107510A patent/HK1036417A1/xx not_active IP Right Cessation
-
2006
- 2006-07-14 US US11/487,554 patent/US20060257476A1/en not_active Abandoned
-
2007
- 2007-01-15 CY CY20071100050T patent/CY1105924T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2328703C (en) | 2007-10-30 |
EP1083885A1 (en) | 2001-03-21 |
JP4827296B2 (ja) | 2011-11-30 |
KR100724016B1 (ko) | 2007-05-31 |
KR20010052717A (ko) | 2001-06-25 |
CN1301149A (zh) | 2001-06-27 |
KR20070040426A (ko) | 2007-04-16 |
CA2328703A1 (en) | 1999-12-16 |
CY1105924T1 (el) | 2011-04-06 |
HUP0102206A3 (en) | 2002-12-28 |
AU753241B2 (en) | 2002-10-10 |
BR9910481A (pt) | 2001-01-09 |
ATE349203T1 (de) | 2007-01-15 |
EA004311B1 (ru) | 2004-02-26 |
EA200100024A1 (ru) | 2001-06-25 |
PL200163B1 (pl) | 2008-12-31 |
HK1036417A1 (en) | 2002-01-04 |
AU4213499A (en) | 1999-12-30 |
US6177101B1 (en) | 2001-01-23 |
ES2277682T3 (es) | 2007-07-16 |
PL344328A1 (en) | 2001-10-22 |
DK1083885T3 (da) | 2007-02-26 |
ZA200006090B (en) | 2001-10-29 |
WO1999063970A1 (en) | 1999-12-16 |
DE69934582T2 (de) | 2007-10-04 |
PT1083885E (pt) | 2007-01-31 |
AU753241C (en) | 2003-05-08 |
US7108864B1 (en) | 2006-09-19 |
CN1237958C (zh) | 2006-01-25 |
DE69934582D1 (de) | 2007-02-08 |
JP2002517430A (ja) | 2002-06-18 |
US20060257476A1 (en) | 2006-11-16 |
NZ508762A (en) | 2003-07-25 |
EP1083885B1 (en) | 2006-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0102206A2 (hu) | Delavirdint tartalmazó tabletta formájú készítmény | |
HK1046244A1 (en) | Controlled release and taste masking oral pharmaceutical compositions. | |
MY125766A (en) | Flash-melt oral dosage formulation | |
BR9908438A (pt) | Tabletes de desintegração rápida | |
HUP0500509A2 (hu) | Azonnali felszabadulást biztosító mikronizált gyógyászati és gyógytáp porok | |
GEP20053420B (en) | Sustained Release Ranolanolazine Formulation | |
HUP0100072A3 (en) | Phenoxazine, phenthiazine derivatives, their use in medicine; process for their preparation and pharmaceutical compositions containing them | |
BR9912979B1 (pt) | composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan. | |
AU3080895A (en) | Novel piperazides derived from arylpiperazine, processes for their preparation, their use as medicaments and pharmaceutical compositions comprising them | |
HUP0103883A2 (hu) | Új, késleltetett felszabadulású, orális készítmények | |
HUP0202497A2 (hu) | Orális, hidrodinamikailag szabályozott hatóanyag leadású készítmény | |
MY127350A (en) | Flash-melt oral dose formulations | |
HUP0004966A2 (en) | Pharmaceutical composition for oral administration in the form of matrix tablet enabling the prolonged release of trimetazidine | |
HUP9900154A2 (hu) | Trovafloxacin-mezilát tabletta | |
ZA200108001B (en) | Processes for making pharmaceutical oral ECB formulations and compositions. | |
MXPA04003346A (es) | Formulacion de dosis oral de disolucion instantanea. | |
DE60202590D1 (de) | 2h-1-benzopyran-derivate, prozesse zu ihrer herstellung und pharmazeutische zusammensetzungen | |
IL136142A0 (en) | High drug load immediate and modified release oral dosage formulations and processes for their manufacture | |
DE60108354D1 (de) | 2H-1-Benzopyran-Derivative, Prozesse zu ihrer Herstellung und Pharmazeutische Zusammensetzungen | |
ZA200110073B (en) | 14β-H-Sterols, pharmaceutical compositions comprising them and use of these derivatives for the preparation of meiosis regulating medicaments. | |
HUP0200208A3 (en) | L-arabino-disaccharides of anthracyclines, processes for their preparation, and pharmaceutical compositions containing them and their use | |
YU28404A (sh) | Brzo topljiva formulacija za oralno doziranje |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |