HUP0101078A2 - Kitináz kitinkötő fragmentek - Google Patents

Kitináz kitinkötő fragmentek

Info

Publication number
HUP0101078A2
HUP0101078A2 HU0101078A HUP0101078A HUP0101078A2 HU P0101078 A2 HUP0101078 A2 HU P0101078A2 HU 0101078 A HU0101078 A HU 0101078A HU P0101078 A HUP0101078 A HU P0101078A HU P0101078 A2 HUP0101078 A2 HU P0101078A2
Authority
HU
Hungary
Prior art keywords
chitin
binding fragments
products
treatment
methods
Prior art date
Application number
HU0101078A
Other languages
English (en)
Inventor
Patrick W. Gray
Larry W. Tjoelker
Original Assignee
Icos Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corporation filed Critical Icos Corporation
Publication of HUP0101078A2 publication Critical patent/HUP0101078A2/hu
Publication of HUP0101078A3 publication Critical patent/HUP0101078A3/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961—Plant cells or fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)

Abstract

A jelen találmány a humán kitináz kitinkötő fragmentjeit, fragmentanalógokat, az ilyen fragmenteket és analógokat kódoló tisztított ésizolált polinukleotid szekvenciákat, és a humán kitináz fragmenttermékek rekombináns termeléséhez szükséges anyagokat és módszereketbiztosít, mely módszerektől azt várjuk, hogy hasznosak a kitindetektálásához való belső termékekként, a kitin kötéséhez és agombafertőzések kezeléséhez vagy a gombafertőzések kezeléséhez hasznostermékek kifejlesztéséhez. Ó
HU0101078A 1998-03-12 1999-03-12 Chitinase chitin-binding fragments HUP0101078A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/039,198 US6200951B1 (en) 1998-03-12 1998-03-12 Chitinase chitin-binding fragments
PCT/US1999/005343 WO1999046390A1 (en) 1998-03-12 1999-03-12 Chitinase chitin-binding fragments

Publications (2)

Publication Number Publication Date
HUP0101078A2 true HUP0101078A2 (hu) 2001-07-30
HUP0101078A3 HUP0101078A3 (en) 2002-09-30

Family

ID=21904197

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101078A HUP0101078A3 (en) 1998-03-12 1999-03-12 Chitinase chitin-binding fragments

Country Status (14)

Country Link
US (3) US6200951B1 (hu)
EP (1) EP1078073A1 (hu)
JP (1) JP2002505882A (hu)
CN (1) CN1357046A (hu)
AU (1) AU763582B2 (hu)
BR (1) BR9908724A (hu)
CA (1) CA2323070A1 (hu)
HU (1) HUP0101078A3 (hu)
IL (1) IL138375A0 (hu)
NO (1) NO20004522L (hu)
PL (1) PL343197A1 (hu)
RU (1) RU2000123559A (hu)
SK (1) SK13542000A3 (hu)
WO (1) WO1999046390A1 (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7741000A (en) * 1999-09-30 2001-04-30 Icos Corporation Chitinase immunoglobulin fusion products
US7754676B2 (en) 2000-09-15 2010-07-13 The United States Of America As Represented By The Department Of Health And Human Services Defensin-antigen fusion proteins
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
HUP0400659A3 (en) 2001-07-24 2005-06-28 Zhu Zhou Woodbridge Methods, compositions and kits relating to chitinases and chitinase-like molecules and inflammatory disease
US7632654B2 (en) * 2002-04-29 2009-12-15 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Means and methods for detecting endoglycosidase activity
MXPA04011390A (es) * 2002-05-16 2005-02-17 Sepracor Inc Aminas que inhiben un transportador de anandamida de mamifero, y metodos de uso de las mismas.
JP2006519771A (ja) * 2003-01-07 2006-08-31 ジェノバ・リミテッド 心臓血管障害で減少する分泌ポリペプチド種（チトトリオシダーゼ由来のフラグメント）
US20070099234A1 (en) * 2003-06-27 2007-05-03 New England Biolabs, Inc. Specific detection of chitin using chitin-binding domain
ES2348303T3 (es) * 2003-12-08 2010-12-02 Cpex Pharmaceuticals, Inc. Composiciones farmacauticas y procedimientos de tratamiento con insulina.
US8377650B2 (en) * 2006-03-17 2013-02-19 The Norwegian University Of Life Sciences (Umb) Method of enhancing degradation of chitin
FR2908654B1 (fr) * 2006-11-20 2014-04-04 Oreal Utilisation cosmetique de proteines de type chitinase
AU2009207923A1 (en) * 2008-01-23 2009-07-30 Rigshospitalet Classification of individuals suffering from cardiovascular diseases according to survival prognoses as found by measuring the levels of biomarker YKL-40
US8697384B2 (en) 2008-01-23 2014-04-15 Herlev Hospital YKL-40 as a general marker for non-specific disease
AU2009291312A1 (en) 2008-09-15 2010-03-18 Herlev Hospital YKL-40 as a marker for gastrointestinal cancers
JP5036741B2 (ja) * 2009-02-18 2012-09-26 中原大學 翻訳段階で自己切断活性を有するポリヌクレオチド配列を同定するための方法およびシステム
WO2011135578A1 (en) 2010-04-28 2011-11-03 Chetan Balar Composition comprising chitin and tinosporin for use in the treatment of viral diseases
US9933425B2 (en) 2014-04-10 2018-04-03 MEP Equine Solutions LLC Method for the quantification of parasite eggs in feces
EP3908263A4 (en) * 2019-01-08 2023-04-19 University of Georgia Research Foundation, Inc. TARGETED NANOPARTICLES AND THEIR USE IN RELATION TO FUNGAL INFECTIONS
CN109943621B (zh) * 2019-01-22 2022-07-01 美林美邦（厦门）生物科技有限公司 来自弧菌属的碱性几丁质酶在真菌染色中的应用
BR102020002165A2 (pt) * 2020-01-31 2021-11-30 Fundação Oswaldo Cruz Anticorpo, seu uso, composição farmacêutica o compreendendo, método de diagnóstico de infecções fúngicas, kit de diagnóstico de infecções fúngicas e método para tratamento de infecções fúngicas.
WO2023074415A1 (ja) * 2021-10-25 2023-05-04 学校法人東京薬科大学 キチン結合ポリペプチドならびにキチンの検出方法および検出キット

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587292A (en) * 1987-05-22 1996-12-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Diagnosis of fungal infections with a chitinase
US5258502A (en) * 1989-01-30 1993-11-02 Massachusetts Institute Of Technology Immobilization and purification of fusion proteins using chitin-binding ability
EP0505500B1 (en) 1989-12-22 1997-07-30 Applied Research Systems Ars Holding N.V. Endogenous gene expression modification with regulatory element by way of homologous recombination
EP0539573A4 (en) 1991-05-15 1993-12-29 Cell Genesys, Inc. Genomic modifications with homologous dna targeting
US5326561A (en) 1992-12-15 1994-07-05 Cornell Research Foundation, Inc. Antifungal synergistic combination of enzyme fungicide and non-enzymatic fungicide and use thereof
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
US5496934A (en) * 1993-04-14 1996-03-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acids encoding a cellulose binding domain
US5561051A (en) 1994-06-14 1996-10-01 American Cyanamid Company Screen for inhibitors of chitinase
US5928928A (en) 1995-06-07 1999-07-27 Universiteit Van Amsterdam Human chitinase, its recombinant production, its use for decomposing chitin, its use in therapy or prophylaxis against infection diseases
AU2593797A (en) 1996-03-29 1997-10-22 Human Genome Sciences, Inc. Chitotriosidase
US20030017570A1 (en) 1996-06-14 2003-01-23 Patrick W. Gray Chitinase materials and methods

Also Published As

Publication number Publication date
WO1999046390A1 (en) 1999-09-16
BR9908724A (pt) 2000-11-21
RU2000123559A (ru) 2002-12-27
JP2002505882A (ja) 2002-02-26
US20030143216A1 (en) 2003-07-31
PL343197A1 (en) 2001-07-30
HUP0101078A3 (en) 2002-09-30
EP1078073A1 (en) 2001-02-28
US6399571B1 (en) 2002-06-04
SK13542000A3 (sk) 2001-07-10
IL138375A0 (en) 2001-10-31
NO20004522D0 (no) 2000-09-11
AU763582B2 (en) 2003-07-24
AU2998999A (en) 1999-09-27
CN1357046A (zh) 2002-07-03
NO20004522L (no) 2000-11-01
CA2323070A1 (en) 1999-09-16
US6200951B1 (en) 2001-03-13

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees