HUP0004326A2 - A tumor-szupresszor génterápia és a kemoterápia kombinálása a daganatok kezelésében - Google Patents
A tumor-szupresszor génterápia és a kemoterápia kombinálása a daganatok kezelésébenInfo
- Publication number
- HUP0004326A2 HUP0004326A2 HU0004326A HUP0004326A HUP0004326A2 HU P0004326 A2 HUP0004326 A2 HU P0004326A2 HU 0004326 A HU0004326 A HU 0004326A HU P0004326 A HUP0004326 A HU P0004326A HU P0004326 A2 HUP0004326 A2 HU P0004326A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- tumor suppressor
- neoplasms
- chemotherapy
- gene therapy
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 108700025716 Tumor Suppressor Genes Proteins 0.000 title 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 title 1
- 238000002512 chemotherapy Methods 0.000 title 1
- 238000001415 gene therapy Methods 0.000 title 1
- 206010006187 Breast cancer Diseases 0.000 abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 abstract 2
- 102000001742 Tumor Suppressor Proteins Human genes 0.000 abstract 2
- 108010040002 Tumor Suppressor Proteins Proteins 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 230000003463 hyperproliferative effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000000225 tumor suppressor protein Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Electrotherapy Devices (AREA)
Abstract
A találmány tárgyát emlősrák- vagy hiperproliferatív sejtek kezeléséreszolgáló eljárás képezi, amelynek során az említett sejteket egytumorszuppresszor fehérjével vagy tumorszuppresszor nukleinsavval,továbbá legalább egy adjunktív rákellenes szerrel hozzák érintkezésbe.A jelen találmány tárgya továbbá egy olyan gyógyszerészeti készítményis, amely egy tumorszuppresszor fehérjét vagy tumorszuppresszornukleinsavat és legalább egy adjunktív rákellenes szert tartalmaz,valamint egy emlősrák- vagy hiperproliferatív sejtek kezeléséreszolgáló kit is. Ó
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80176597A | 1997-02-18 | 1997-02-18 | |
US80175597A | 1997-02-18 | 1997-02-18 | |
US80128597A | 1997-02-18 | 1997-02-18 | |
US3806597P | 1997-02-18 | 1997-02-18 | |
US80168197A | 1997-02-18 | 1997-02-18 | |
US4783497P | 1997-05-28 | 1997-05-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0004326A2 true HUP0004326A2 (hu) | 2001-02-28 |
HUP0004326A3 HUP0004326A3 (en) | 2003-07-28 |
Family
ID=27556335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0004326A HUP0004326A3 (en) | 1997-02-18 | 1998-02-17 | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0969720B1 (hu) |
JP (1) | JP2001511815A (hu) |
KR (2) | KR100688409B1 (hu) |
CN (1) | CN1248731C (hu) |
AT (1) | ATE361668T1 (hu) |
AU (1) | AU737621B2 (hu) |
BR (1) | BR9807418A (hu) |
CA (1) | CA2282683A1 (hu) |
CZ (1) | CZ298488B6 (hu) |
DE (1) | DE69837754T2 (hu) |
ES (1) | ES2287974T3 (hu) |
HK (1) | HK1026579A1 (hu) |
HU (1) | HUP0004326A3 (hu) |
IL (2) | IL131447A0 (hu) |
NO (1) | NO993943L (hu) |
NZ (1) | NZ337283A (hu) |
PL (1) | PL193767B1 (hu) |
SK (1) | SK285969B6 (hu) |
WO (1) | WO1998035554A2 (hu) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6524832B1 (en) | 1994-02-04 | 2003-02-25 | Arch Development Corporation | DNA damaging agents in combination with tyrosine kinase inhibitors |
SK6598A3 (en) | 1995-07-17 | 1998-09-09 | Univ Texas | P16 expression constructs and their application in cancer therapy |
US7163925B1 (en) | 1995-07-17 | 2007-01-16 | Board Of Regents, The University Of Texas System | p16 expression constructs and their application in cancer therapy |
ES2383640T3 (es) | 1996-11-20 | 2012-06-25 | Crucell Holland B.V. | Composiciones de adenovirus que pueden obtenerse mediante un método de producción y purificación mejorado |
US7732129B1 (en) | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
TW581763B (en) * | 1997-12-22 | 2004-04-01 | Schering Corp | Combination and pharmaceutical composition comprising FPT inhibitor for treating proliferative diseases |
US6096757A (en) | 1998-12-21 | 2000-08-01 | Schering Corporation | Method for treating proliferative diseases |
CA2325561A1 (en) * | 1998-04-22 | 1999-10-28 | Inex Pharmaceuticals Corporation | Combination therapy using nucleic acids and conventional drugs |
US6689600B1 (en) | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
WO2000056351A2 (en) * | 1999-03-19 | 2000-09-28 | Schering Corporation | Combination use of gemcitabine and tumor suppressor gene therapy in the treatment of neoplasms |
US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
US6911200B2 (en) | 2000-03-24 | 2005-06-28 | Cell Genesys, Inc. | Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation |
US7048920B2 (en) | 2000-03-24 | 2006-05-23 | Cell Genesys, Inc. | Recombinant oncolytic adenovirus for human melanoma |
JP4564714B2 (ja) * | 2000-11-27 | 2010-10-20 | ミナーヴァ・バイオテクノロジーズ・コーポレーション | 診断用腫瘍マーカー、腫瘍形成の阻害のための薬物スクリーニング、並びにがん治療用の組成物及び方法 |
EP1340498A1 (en) * | 2002-03-01 | 2003-09-03 | Schering Aktiengesellschaft | Use of epothilones in the treatment of brain diseases associated with proliferative processes |
US7364727B2 (en) | 2002-07-22 | 2008-04-29 | Cell Genesys, Inc. | Metastatic colon cancer specific promoter and uses thereof |
WO2005082396A2 (en) | 2003-12-01 | 2005-09-09 | Introgen Therapeutics, Inc. | Use of mda-7 to inhibit infection by pathogenic organisms |
JPWO2005061007A1 (ja) * | 2003-12-24 | 2007-07-12 | 学校法人 聖マリアンナ医科大学 | 癌の抑制方法 |
CA2551543A1 (en) * | 2003-12-24 | 2005-07-07 | Locomogene, Inc. | Method of suppressing cancer |
CA2586107A1 (en) | 2004-11-03 | 2006-05-18 | Introgen Therapeutics Inc. | A novel method for the production and purification of adenoviral vectors |
AU2016219350A1 (en) | 2015-02-10 | 2017-08-24 | Minerva Biotechnologies Corporation | Humanized anti-MUC1* antibodies |
CN106692989A (zh) * | 2017-03-07 | 2017-05-24 | 大连民族大学 | 一种药物脂质体/p53基因复合物及其制备方法和应用 |
CN109200295A (zh) * | 2018-10-08 | 2019-01-15 | 蚌埠医学院 | 一种用于治疗卵巢癌的药物组合物及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5747469A (en) * | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
CA2173963C (en) * | 1993-10-15 | 2002-03-19 | W. Robert Bishop | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
KR100295224B1 (ko) * | 1995-12-22 | 2001-09-17 | 둘락 노먼 씨. | G-단백질기능의억제및증식성질환의치료에유용한트리사이클릭아미드 |
-
1998
- 1998-02-17 WO PCT/US1998/003514 patent/WO1998035554A2/en active IP Right Grant
- 1998-02-17 HU HU0004326A patent/HUP0004326A3/hu unknown
- 1998-02-17 PL PL98335334A patent/PL193767B1/pl not_active IP Right Cessation
- 1998-02-17 SK SK1122-99A patent/SK285969B6/sk not_active IP Right Cessation
- 1998-02-17 ES ES98910038T patent/ES2287974T3/es not_active Expired - Lifetime
- 1998-02-17 DE DE69837754T patent/DE69837754T2/de not_active Expired - Fee Related
- 1998-02-17 AU AU64380/98A patent/AU737621B2/en not_active Ceased
- 1998-02-17 CN CNB988042541A patent/CN1248731C/zh not_active Expired - Fee Related
- 1998-02-17 BR BR9807418-0A patent/BR9807418A/pt not_active Application Discontinuation
- 1998-02-17 CZ CZ0293399A patent/CZ298488B6/cs not_active IP Right Cessation
- 1998-02-17 KR KR1020057021095A patent/KR100688409B1/ko not_active IP Right Cessation
- 1998-02-17 KR KR1019997007475A patent/KR100620939B1/ko not_active IP Right Cessation
- 1998-02-17 JP JP53603398A patent/JP2001511815A/ja not_active Ceased
- 1998-02-17 CA CA002282683A patent/CA2282683A1/en not_active Abandoned
- 1998-02-17 EP EP98910038A patent/EP0969720B1/en not_active Expired - Lifetime
- 1998-02-17 AT AT98910038T patent/ATE361668T1/de not_active IP Right Cessation
- 1998-02-17 NZ NZ337283A patent/NZ337283A/en unknown
- 1998-02-17 IL IL13144798A patent/IL131447A0/xx unknown
-
1999
- 1999-08-17 NO NO993943A patent/NO993943L/no not_active Application Discontinuation
-
2000
- 2000-07-12 HK HK00104319A patent/HK1026579A1/xx not_active IP Right Cessation
-
2008
- 2008-11-30 IL IL195605A patent/IL195605A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1248731C (zh) | 2006-04-05 |
PL193767B1 (pl) | 2007-03-30 |
EP0969720A2 (en) | 2000-01-12 |
NO993943D0 (no) | 1999-08-17 |
CA2282683A1 (en) | 1998-08-20 |
AU737621B2 (en) | 2001-08-23 |
SK112299A3 (en) | 2000-12-11 |
ATE361668T1 (de) | 2007-06-15 |
DE69837754T2 (de) | 2008-02-07 |
CN1252689A (zh) | 2000-05-10 |
DE69837754D1 (de) | 2007-06-21 |
NZ337283A (en) | 2001-02-23 |
EP0969720A4 (en) | 2004-05-12 |
KR100688409B1 (ko) | 2007-03-02 |
HUP0004326A3 (en) | 2003-07-28 |
AU6438098A (en) | 1998-09-08 |
ES2287974T3 (es) | 2007-12-16 |
EP0969720B1 (en) | 2007-05-09 |
IL131447A0 (en) | 2001-01-28 |
JP2001511815A (ja) | 2001-08-14 |
CZ298488B6 (cs) | 2007-10-17 |
KR20000071185A (ko) | 2000-11-25 |
BR9807418A (pt) | 2002-01-22 |
CZ293399A3 (cs) | 2000-03-15 |
KR100620939B1 (ko) | 2006-09-06 |
WO1998035554A2 (en) | 1998-08-20 |
IL195605A0 (en) | 2011-08-01 |
SK285969B6 (sk) | 2007-12-06 |
PL335334A1 (en) | 2000-04-25 |
NO993943L (no) | 1999-10-15 |
WO1998035554A3 (en) | 1998-11-26 |
HK1026579A1 (en) | 2000-12-22 |
KR20050113287A (ko) | 2005-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |