HUP0003583A2 - Ibuprofen tartalmú gyógyászati szerek - Google Patents

Ibuprofen tartalmú gyógyászati szerek

Info

Publication number
HUP0003583A2
HUP0003583A2 HU0003583A HUP0003583A HUP0003583A2 HU P0003583 A2 HUP0003583 A2 HU P0003583A2 HU 0003583 A HU0003583 A HU 0003583A HU P0003583 A HUP0003583 A HU P0003583A HU P0003583 A2 HUP0003583 A2 HU P0003583A2
Authority
HU
Hungary
Prior art keywords
ibuprofen
preparation
water
substance
active ingredient
Prior art date
Application number
HU0003583A
Other languages
English (en)
Inventor
Jeffrey Dickinson
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Publication of HUP0003583A2 publication Critical patent/HUP0003583A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

A találmány tárgyát olyan ibuprofenkompozíció képezi, amelyből vízhozzáadásával 7-nél kisebb pH-jú vizes gyógyszerkészítmény állíthatóelő. A nevezett ibuprofenkompozíció egy vagy több gyógyhatású anyagot,beleértve egy ibuprofen hatóanyagot is, amely utóbbi egy 100 °C-nálalacsonyabb olvadáspontú ibuprofen hatóanyagot képez, amikor anevezett ibuprofen gyógyszert vízzel elegyítik, továbbá egyfoszfolipid anyagot és - szükség esetén - egy savas jellegű anyagottartalmaz. Ez a foszfolipid anyag képes arra, hogy a készítményhez 80-100 °C hőmérsékletű víz hozzáadása után a készítményben lévő vízbenoldhatatlan hatóanyago(ka)t, ideértve az ibuprofen hatóanyagot is, avizes fázistól elkülönülő (diszkrét) fázisban tartsa, és a vízhozzáadására keletkező vizes készítmény (emulzió vagy szuszpenzió)vizes fázisa lényegében mentes legyen az ibuprofen hatóanyagtól. Atalálmány tárgyát képezi továbbá eljárás folyékony, kellemes ízűivólékészítmények (különösen meleg emulziók) előállítására, illetve atalálmány szerinti készítmények gyulladás, fájdalom és/vagy lázkezelésére szolgáló gyógyszerek készítésére való alkalmazása. Ó
HU0003583A 1996-12-10 1997-12-09 Ibuprofen tartalmú gyógyászati szerek HUP0003583A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9625589.8A GB9625589D0 (en) 1996-12-10 1996-12-10 Therapeutic agents
PCT/EP1997/007137 WO1998025595A2 (en) 1996-12-10 1997-12-09 Aqueous drink composition comprising ibuprofen

Publications (1)

Publication Number Publication Date
HUP0003583A2 true HUP0003583A2 (hu) 2001-04-28

Family

ID=10804192

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003583A HUP0003583A2 (hu) 1996-12-10 1997-12-09 Ibuprofen tartalmú gyógyászati szerek

Country Status (27)

Country Link
US (1) US6287592B1 (hu)
EP (1) EP0946156B1 (hu)
JP (1) JP2001508768A (hu)
KR (1) KR20000069418A (hu)
CN (1) CN1275910A (hu)
AR (1) AR010758A1 (hu)
AT (1) ATE213628T1 (hu)
AU (1) AU723608B2 (hu)
BG (1) BG103552A (hu)
CA (1) CA2274773C (hu)
CZ (1) CZ204599A3 (hu)
DE (1) DE69710774T2 (hu)
DK (1) DK0946156T3 (hu)
ES (1) ES2173516T3 (hu)
GB (1) GB9625589D0 (hu)
HK (1) HK1021941A1 (hu)
HU (1) HUP0003583A2 (hu)
IL (1) IL130367A0 (hu)
NO (1) NO992806L (hu)
NZ (1) NZ336079A (hu)
PL (1) PL338920A1 (hu)
PT (1) PT946156E (hu)
RU (1) RU2207851C2 (hu)
SK (1) SK76799A3 (hu)
TR (1) TR199901250T2 (hu)
WO (1) WO1998025595A2 (hu)
ZA (1) ZA9711029B (hu)

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US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
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US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
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US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
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US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US20130309215A1 (en) * 2012-05-15 2013-11-21 Mika Pharma Gesellschaft Fur Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh Pharmaceutical composition
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Also Published As

Publication number Publication date
KR20000069418A (ko) 2000-11-25
NO992806D0 (no) 1999-06-09
DE69710774T2 (de) 2002-10-31
EP0946156A2 (en) 1999-10-06
ES2173516T3 (es) 2002-10-16
PL338920A1 (en) 2000-11-20
JP2001508768A (ja) 2001-07-03
RU2207851C2 (ru) 2003-07-10
CA2274773C (en) 2008-08-26
WO1998025595A3 (en) 2000-05-04
IL130367A0 (en) 2000-06-01
ZA9711029B (en) 1998-06-10
DE69710774D1 (de) 2002-04-04
AU5760598A (en) 1998-07-03
ATE213628T1 (de) 2002-03-15
CZ204599A3 (cs) 1999-09-15
GB9625589D0 (en) 1997-01-29
BG103552A (en) 2000-04-28
TR199901250T2 (xx) 2000-06-21
DK0946156T3 (da) 2002-06-10
WO1998025595A2 (en) 1998-06-18
NZ336079A (en) 2001-03-30
NO992806L (no) 1999-08-09
AU723608B2 (en) 2000-08-31
PT946156E (pt) 2002-08-30
US6287592B1 (en) 2001-09-11
CN1275910A (zh) 2000-12-06
SK76799A3 (en) 2000-05-16
EP0946156B1 (en) 2002-02-27
HK1021941A1 (en) 2000-07-21
CA2274773A1 (en) 1998-06-18
AR010758A1 (es) 2000-07-12

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