HUP0002852A3 - A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives - Google Patents

A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives

Info

Publication number
HUP0002852A3
HUP0002852A3 HU0002852A HUP0002852A HUP0002852A3 HU P0002852 A3 HUP0002852 A3 HU P0002852A3 HU 0002852 A HU0002852 A HU 0002852A HU P0002852 A HUP0002852 A HU P0002852A HU P0002852 A3 HUP0002852 A3 HU P0002852A3
Authority
HU
Hungary
Prior art keywords
triphenil
disorders
preventing
dependent diseases
ethylene derivatives
Prior art date
Application number
HU0002852A
Other languages
English (en)
Original Assignee
Univ Durham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Durham filed Critical Univ Durham
Publication of HUP0002852A2 publication Critical patent/HUP0002852A2/hu
Publication of HUP0002852A3 publication Critical patent/HUP0002852A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0002852A 1997-08-15 1998-08-14 A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives HUP0002852A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5588197P 1997-08-15 1997-08-15
PCT/US1998/016864 WO1999008682A1 (en) 1997-08-15 1998-08-14 A method of preventing or treating estrogen-dependent diseases and disorders

Publications (2)

Publication Number Publication Date
HUP0002852A2 HUP0002852A2 (hu) 2001-10-28
HUP0002852A3 true HUP0002852A3 (en) 2001-11-28

Family

ID=22000784

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002852A HUP0002852A3 (en) 1997-08-15 1998-08-14 A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives

Country Status (21)

Country Link
US (1) US7307102B2 (hu)
EP (1) EP1019057B1 (hu)
JP (1) JP2001515038A (hu)
KR (1) KR20010022956A (hu)
CN (1) CN1275911A (hu)
AT (1) ATE411016T1 (hu)
AU (1) AU757206B2 (hu)
BR (1) BR9811946A (hu)
CA (1) CA2301032C (hu)
CZ (1) CZ300929B6 (hu)
DE (1) DE69840126D1 (hu)
EE (1) EE200000077A (hu)
ES (1) ES2312189T3 (hu)
HU (1) HUP0002852A3 (hu)
IL (1) IL134445A0 (hu)
NO (1) NO20000752L (hu)
NZ (1) NZ502738A (hu)
PL (1) PL338555A1 (hu)
RU (1) RU2214236C2 (hu)
UA (1) UA70925C2 (hu)
WO (1) WO1999008682A1 (hu)

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US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
AU4676999A (en) 1998-06-12 1999-12-30 Ligand Pharmaceuticals, Inc. Treatment of anti-estrogen resistant breast cancer using rxr modulators
GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
CN1390126B (zh) * 1999-07-06 2012-06-13 恩多研究公司 选择性雌激素受体调节剂在制备用于治疗或降低肥胖症发展危险性的药物中的用途
CO5271709A1 (es) 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
US6528681B2 (en) * 2000-04-05 2003-03-04 Bristol-Meyers Squibb Pharma Company Halogenated triphenylethylene derivatives as selective estrogen receptor modulators
US6417394B2 (en) * 2000-04-05 2002-07-09 Bristol Myers Squibb Pharma Company Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
USRE41236E1 (en) * 2000-07-05 2010-04-20 Seely Andrew J E Method and apparatus for multiple patient parameter variability analysis and display
WO2002064142A1 (en) * 2001-02-15 2002-08-22 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with antiestrogen agents
US20020164581A1 (en) * 2001-03-12 2002-11-07 Chawnshang Chang Methods for identifying compounds that do not attenuate the protective effects of estrogen
HUP0500573A2 (hu) * 2001-08-11 2005-11-28 Bristol-Myers Squibb Pharma Company Trifenil-etilén származékok, mint szelektív ösztrogén receptor modulátorok és ezeket tartalmazó gyógyszerkészítmények
NZ551955A (en) 2004-06-23 2010-08-27 Revision Therapeutics Inc Methods and compositions for treating ophthalmic conditions with retinyl derivatives
JP2008519054A (ja) 2004-11-04 2008-06-05 シリオン セラピューティクス， インコーポレイテッド レチノール−レチノール結合タンパク質（ｒｂｐ）−トランスチレチン（ｔｔｒ）複合体の形成のモジュレーター
BRPI0520207A2 (pt) * 2004-12-08 2012-09-25 Revision Therapeutics Inc uso de uma quantidade eficaz de um primeiro composto, e, medicamento sistemicamente formulado
US20060264413A1 (en) * 2005-04-18 2006-11-23 Sri International Method and composition for inhibiting cell proliferation and angiogenesis
UA81382C2 (en) * 2005-07-11 2007-12-25 Composition for treating retinol-related diseases by modulation of retinol binding
EP2206053A4 (en) 2007-10-03 2012-11-21 Ottawa Hospital Res Inst METHOD AND DEVICE FOR MONITORING THE VARIABILITY OF PHYSIOLOGICAL PARAMETERS OVER TIME FOR ONE OR MORE ORGANS
WO2009151683A2 (en) 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
BRPI0920927A2 (pt) 2008-11-13 2019-09-24 Link Medicine Corp derivados de azaquinolinona e usos dos mesmos
PL2580210T3 (pl) 2010-06-10 2017-09-29 Seragon Pharmaceuticals, Inc. Modulatory receptora estrogenowego i ich zastosowania
WO2011159769A2 (en) 2010-06-17 2011-12-22 Aragon Pharmaceuticals, Inc. Indane estrogen receptor modulators and uses thereof
GB2483736B (en) 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
BR112014014124A2 (pt) 2011-12-14 2017-08-22 Seragon Pharmaceutical Inc Moduladores do receptor de estrogênio fluorados e usos dos mesmos
CN102532073A (zh) * 2011-12-30 2012-07-04 北京赛林泰医药技术有限公司 作为选择性雌激素受体调节剂的乙烯衍生物
CN102584687A (zh) * 2011-12-30 2012-07-18 北京赛林泰医药技术有限公司 作为选择性雌激素受体调节剂的乙烯衍生物
NZ630124A (en) 2012-03-20 2016-01-29 Seragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
US10118910B2 (en) * 2015-12-09 2018-11-06 The Board Of Trustees Of The University Of Illinois Benzothiophene-based selective estrogen receptor downregulators
EP3658527A4 (en) * 2017-07-28 2021-04-07 Recurium IP Holdings, LLC ACRYLIC ACID ANALOGUES

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AU659157B2 (en) 1991-04-30 1995-05-11 Asahi Kasei Kogyo Kabushiki Kaisha Triphenylethylene derivative and pharmaceutical preparation containing the same
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Also Published As

Publication number Publication date
ES2312189T3 (es) 2009-02-16
AU8906398A (en) 1999-03-08
EE200000077A (et) 2000-12-15
RU2214236C2 (ru) 2003-10-20
CN1275911A (zh) 2000-12-06
BR9811946A (pt) 2000-08-22
UA70925C2 (uk) 2004-11-15
EP1019057A1 (en) 2000-07-19
DE69840126D1 (de) 2008-11-27
PL338555A1 (en) 2000-11-06
CZ2000531A3 (en) 2001-05-16
AU757206B2 (en) 2003-02-06
NO20000752D0 (no) 2000-02-15
NO20000752L (no) 2000-02-15
IL134445A0 (en) 2001-04-30
CA2301032C (en) 2009-01-13
ATE411016T1 (de) 2008-10-15
CA2301032A1 (en) 1999-02-25
US20030232795A1 (en) 2003-12-18
HUP0002852A2 (hu) 2001-10-28
CZ300929B6 (cs) 2009-09-16
US7307102B2 (en) 2007-12-11
NZ502738A (en) 2002-06-28
WO1999008682A1 (en) 1999-02-25
KR20010022956A (ko) 2001-03-26
EP1019057A4 (en) 2006-06-14
JP2001515038A (ja) 2001-09-18
EP1019057B1 (en) 2008-10-15

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