HUE047789T2 - RGD peptidek és (bakterio)klorofill fényérzékenyítõk konjugátumai, valamint ezek alkalmazásai - Google Patents

RGD peptidek és (bakterio)klorofill fényérzékenyítõk konjugátumai, valamint ezek alkalmazásai

Info

Publication number
HUE047789T2
HUE047789T2 HUE07805515A HUE07805515A HUE047789T2 HU E047789 T2 HUE047789 T2 HU E047789T2 HU E07805515 A HUE07805515 A HU E07805515A HU E07805515 A HUE07805515 A HU E07805515A HU E047789 T2 HUE047789 T2 HU E047789T2
Authority
HU
Hungary
Prior art keywords
bacterio
photosensitizers
chlorophyll
conjugates
applications
Prior art date
Application number
HUE07805515A
Other languages
English (en)
Hungarian (hu)
Inventor
Avigdor Scherz
Yoram Salomon
Efrat Rubinstein
Alexander Brandis
Doron Eren
Karin Neimann
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of HUE047789T2 publication Critical patent/HUE047789T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/123Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • C07K5/0817Tripeptides with the first amino acid being basic the first amino acid being Arg
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HUE07805515A 2006-08-23 2007-08-23 RGD peptidek és (bakterio)klorofill fényérzékenyítõk konjugátumai, valamint ezek alkalmazásai HUE047789T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83940906P 2006-08-23 2006-08-23

Publications (1)

Publication Number Publication Date
HUE047789T2 true HUE047789T2 (hu) 2020-05-28

Family

ID=38896083

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE07805515A HUE047789T2 (hu) 2006-08-23 2007-08-23 RGD peptidek és (bakterio)klorofill fényérzékenyítõk konjugátumai, valamint ezek alkalmazásai

Country Status (12)

Country Link
US (1) US20080138278A1 (cg-RX-API-DMAC7.html)
EP (1) EP2061512B1 (cg-RX-API-DMAC7.html)
JP (3) JP2010502574A (cg-RX-API-DMAC7.html)
AU (1) AU2007287205B8 (cg-RX-API-DMAC7.html)
CA (1) CA2661319C (cg-RX-API-DMAC7.html)
DK (1) DK2061512T3 (cg-RX-API-DMAC7.html)
ES (1) ES2763237T3 (cg-RX-API-DMAC7.html)
HU (1) HUE047789T2 (cg-RX-API-DMAC7.html)
IL (1) IL197195A (cg-RX-API-DMAC7.html)
PT (1) PT2061512T (cg-RX-API-DMAC7.html)
RU (1) RU2450018C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008023378A1 (cg-RX-API-DMAC7.html)

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US9161696B2 (en) 2006-09-22 2015-10-20 Masimo Corporation Modular patient monitor
CN101848668A (zh) 2007-09-14 2010-09-29 健康研究有限公司 用于肿瘤显像和治疗的多模态试剂
CA2717060C (en) 2008-02-27 2016-11-01 Avigdor Scherz Rgd-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors
LT5567B (lt) 2008-08-06 2009-04-27 Vilniaus Universitetas Maisto ir su maistu susietų paviršių nukenksminimo būdas
ES2627377T3 (es) * 2008-10-23 2017-07-27 Steba Biotech S.A. Peptidomiméticos que contienen RGD y sus usos
US8263133B2 (en) * 2009-02-18 2012-09-11 The Regents Of The University Of California Multivalent clustering targeting strategy for drug carriers
US9153112B1 (en) 2009-12-21 2015-10-06 Masimo Corporation Modular patient monitor
PL219569B1 (pl) 2010-02-19 2015-05-29 Peptaderm Spółka Z Ograniczoną Odpowiedzialnością Cykliczne tetrapeptydy i ich zastosowanie
WO2012166792A1 (en) 2011-05-31 2012-12-06 North Carolina State University Bacteriochlorin imides
IN2014CN02153A (cg-RX-API-DMAC7.html) * 2011-08-23 2015-05-29 Yeda Res & Dev
US9436645B2 (en) 2011-10-13 2016-09-06 Masimo Corporation Medical monitoring hub
US9943269B2 (en) 2011-10-13 2018-04-17 Masimo Corporation System for displaying medical monitoring data
US10149616B2 (en) 2012-02-09 2018-12-11 Masimo Corporation Wireless patient monitoring device
US10307111B2 (en) 2012-02-09 2019-06-04 Masimo Corporation Patient position detection system
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TWI568747B (zh) * 2012-09-05 2017-02-01 上海晟順生物科技有限公司 同時具溶血栓、清除自由基和血栓靶向功能的新穎化合物及其製備方法和用途
US9749232B2 (en) 2012-09-20 2017-08-29 Masimo Corporation Intelligent medical network edge router
RU2548675C9 (ru) * 2013-05-29 2015-11-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им. М.В. Ломоносова) Аминоамиды в ряду бактериохлорофилла a, обладающие фотодинамической активностью, и способ их получения
JP6263716B2 (ja) * 2013-07-31 2018-01-24 国立大学法人 筑波大学 悪性腫瘍のpet診断用トレーサー
US10832818B2 (en) 2013-10-11 2020-11-10 Masimo Corporation Alarm notification system
US9522925B2 (en) * 2014-11-09 2016-12-20 Hong Kong Baptist University Selective cancer tracking eradicator and the uses thereof
EP3328425B1 (en) * 2015-07-29 2021-08-25 Novartis AG Combined use of anti pd-1 and anti m-csf antibodies in the treatment of cancer
SG10201506686WA (en) * 2015-08-24 2017-03-30 Agency Science Tech & Res Conjugates
AU2016315947B2 (en) 2015-08-31 2021-02-18 Masimo Corporation Wireless patient monitoring systems and methods
CN105837666A (zh) * 2015-12-30 2016-08-10 田梗 一种用于诊断糖尿病性视网膜病的蛋白质
RU2021110230A (ru) * 2016-04-10 2021-05-26 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Комбинированные способы терапии для лечения злокачественной опухоли
US10617302B2 (en) 2016-07-07 2020-04-14 Masimo Corporation Wearable pulse oximeter and respiration monitor
CN107759804B (zh) * 2016-08-19 2019-12-03 四川大学 可定点结合含组氨酸标签蛋白的明胶衍生材料及其制备方法
US11076777B2 (en) 2016-10-13 2021-08-03 Masimo Corporation Systems and methods for monitoring orientation to reduce pressure ulcer formation
US10933134B2 (en) 2017-03-16 2021-03-02 Memorial Sloan Kettering Cancer Center Combination therapies for treatment of cancer
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US12495968B2 (en) 2018-10-12 2025-12-16 Masimo Corporation System for transmission of sensor data using dual communication protocol
CN110215438B (zh) * 2019-07-15 2021-06-29 中国医学科学院生物医学工程研究所 双载蒽环类药物及光敏剂介孔硅纳米粒的制备方法与应用
JP7737391B2 (ja) 2020-03-20 2025-09-10 マシモ・コーポレイション 非侵襲的な体温測定のためのウェアラブルデバイス
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Also Published As

Publication number Publication date
AU2007287205A1 (en) 2008-02-28
WO2008023378A1 (en) 2008-02-28
RU2450018C2 (ru) 2012-05-10
DK2061512T3 (da) 2020-01-20
EP2061512A1 (en) 2009-05-27
WO2008023378A9 (en) 2008-04-10
ES2763237T3 (es) 2020-05-27
US20080138278A1 (en) 2008-06-12
IL197195A (en) 2015-10-29
EP2061512B1 (en) 2019-10-02
IL197195A0 (en) 2009-12-24
RU2009110226A (ru) 2010-09-27
JP6177013B2 (ja) 2017-08-09
CA2661319C (en) 2015-12-01
JP2013231039A (ja) 2013-11-14
JP2017039700A (ja) 2017-02-23
AU2007287205B8 (en) 2013-08-15
PT2061512T (pt) 2020-01-14
JP2010502574A (ja) 2010-01-28
CA2661319A1 (en) 2008-02-28
AU2007287205B2 (en) 2013-04-18

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