HUE037095T2 - Eljárások és reagensek monoklonális ellenanyagok elõállítására - Google Patents

Eljárások és reagensek monoklonális ellenanyagok elõállítására

Info

Publication number
HUE037095T2
HUE037095T2 HUE12711501A HUE12711501A HUE037095T2 HU E037095 T2 HUE037095 T2 HU E037095T2 HU E12711501 A HUE12711501 A HU E12711501A HU E12711501 A HUE12711501 A HU E12711501A HU E037095 T2 HUE037095 T2 HU E037095T2
Authority
HU
Hungary
Prior art keywords
reagents
methods
monoclonal antibodies
creating monoclonal
creating
Prior art date
Application number
HUE12711501A
Other languages
English (en)
Hungarian (hu)
Inventor
Roberto Polakiewicz
Wan Cheung Cheung
John Edward Rush
Sean Andre Beausoleil
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of HUE037095T2 publication Critical patent/HUE037095T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082Hepadnaviridae, e.g. hepatitis B virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE12711501A 2011-03-09 2012-03-09 Eljárások és reagensek monoklonális ellenanyagok elõállítására HUE037095T2 (hu)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161450922P 2011-03-09 2011-03-09
US201161560006P 2011-11-15 2011-11-15
US201161566876P 2011-12-05 2011-12-05
US201261594729P 2012-02-03 2012-02-03

Publications (1)

Publication Number Publication Date
HUE037095T2 true HUE037095T2 (hu) 2018-08-28

Family

ID=45922811

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE12711501A HUE037095T2 (hu) 2011-03-09 2012-03-09 Eljárások és reagensek monoklonális ellenanyagok elõállítására

Country Status (12)

Country Link
US (2) US9920110B2 (OSRAM)
EP (2) EP2683736B1 (OSRAM)
JP (3) JP6211931B2 (OSRAM)
KR (3) KR20190107761A (OSRAM)
CN (2) CN103842379A (OSRAM)
AU (3) AU2012225310B2 (OSRAM)
CA (1) CA2829606C (OSRAM)
DK (1) DK2683736T3 (OSRAM)
ES (1) ES2666301T3 (OSRAM)
HK (1) HK1256304A1 (OSRAM)
HU (1) HUE037095T2 (OSRAM)
WO (1) WO2012122484A1 (OSRAM)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685898B2 (en) 2009-01-15 2014-04-01 Imdaptive, Inc. Adaptive immunity profiling and methods for generation of monoclonal antibodies
EP2783214A2 (en) 2011-11-23 2014-10-01 The Board of Regents of The University of Texas System Proteomic identification of antibodies
DK2823060T3 (en) 2012-03-05 2018-05-28 Adaptive Biotechnologies Corp Determination of associated immune receptor chains from frequency-matched subunits
HUE029357T2 (en) 2012-05-08 2017-02-28 Adaptive Biotechnologies Corp Preparations and devices for measuring and calibrating amplification distortion in multiplex PCR reactions
DK2861760T3 (da) 2012-06-15 2020-03-09 Univ Texas Sekventering med høj kapacitet af flere udskrifter af en enkelt celle
AU2014232314B2 (en) * 2013-03-15 2020-05-14 Adaptive Biotechnologies Corporation Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
US10208125B2 (en) 2013-07-15 2019-02-19 University of Pittsburgh—of the Commonwealth System of Higher Education Anti-mucin 1 binding agents and uses thereof
PT3023777T (pt) * 2013-09-09 2018-01-19 Shimadzu Corp Método para preparar fragmentos peptídicos, kit para preparar fragmentos peptídicos para serem utilizados neste, e método de análise
GB201316644D0 (en) * 2013-09-19 2013-11-06 Kymab Ltd Expression vector production & High-Throughput cell screening
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
EP3132059B1 (en) 2014-04-17 2020-01-08 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
US20170212130A1 (en) * 2014-06-25 2017-07-27 The Rockefeller University Compositions and methods for rapid production of versatile nanobody repertoires
CN105277638A (zh) * 2014-07-22 2016-01-27 沈鹤霄 一种单克隆抗体IgG质谱测序方法
US10392663B2 (en) 2014-10-29 2019-08-27 Adaptive Biotechnologies Corp. Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
CN104560980B (zh) * 2015-01-20 2017-04-05 中国人民解放军第三军医大学 基于高通量测序构建鼠BCR轻链Lamda文库的多重PCR引物和方法
CN104560979B (zh) * 2015-01-20 2017-04-05 中国人民解放军第三军医大学 基于高通量测序构建鼠bcr重链文库的多重pcr引物和方法
ES3002665T3 (en) 2015-02-24 2025-03-07 Adaptive Biotechnologies Corp Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
US10777398B2 (en) 2015-03-06 2020-09-15 Micromass Uk Limited Spectrometric analysis
JP6783240B2 (ja) 2015-03-06 2020-11-11 マイクロマス ユーケー リミテッド 生体内内視鏡的組織同定機器
GB2553918B (en) 2015-03-06 2022-10-12 Micromass Ltd Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
EP3265822B1 (en) 2015-03-06 2021-04-28 Micromass UK Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
US11282688B2 (en) 2015-03-06 2022-03-22 Micromass Uk Limited Spectrometric analysis of microbes
CN108700590B (zh) 2015-03-06 2021-03-02 英国质谱公司 细胞群体分析
EP3570315B1 (en) * 2015-03-06 2024-01-31 Micromass UK Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of biopsy samples
US10513733B2 (en) 2015-03-23 2019-12-24 Board Of Regents, The University Of Texas System High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies
WO2016161273A1 (en) 2015-04-01 2016-10-06 Adaptive Biotechnologies Corp. Method of identifying human compatible t cell receptors specific for an antigenic target
EP3346912A4 (en) * 2015-09-09 2019-08-21 Ubiome Inc. METHOD AND SYSTEM FOR MICROBIAL-DERIVED DIAGNOSTICS AND THERAPEUTIC FOR DISEASES RELATED TO CEREBRO-KRANIOFAZIAL HEALTH
EP3443354B1 (en) 2016-04-14 2025-08-20 Micromass UK Limited Spectrometric analysis of plants
CN106047857B (zh) * 2016-06-01 2020-04-03 苏州金唯智生物科技有限公司 一种发掘特异性功能抗体的方法
CN107525934A (zh) * 2016-06-21 2017-12-29 张效龙 一种测定血液中抗体氨基酸序列的方法
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
CN118497192A (zh) * 2017-03-07 2024-08-16 豪夫迈·罗氏有限公司 发现替代性抗原特异性抗体变体的方法
CN111201238B (zh) * 2017-07-21 2023-09-08 诺夫免疫股份有限公司 产生多特异性抗体混合物及其使用方法
CN109425662A (zh) * 2017-08-23 2019-03-05 深圳华大基因研究院 一种鉴定蛋白的方法及系统
WO2019084538A1 (en) 2017-10-27 2019-05-02 Board Of Regents, The University Of Texas System TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
CN119881293A (zh) 2018-03-21 2025-04-25 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
WO2019183882A1 (zh) * 2018-03-29 2019-10-03 深圳达闼科技控股有限公司 物质检测方法、装置、电子设备及计算机可读存储介质
CN108530533B (zh) * 2018-04-13 2020-09-04 吉林大学 猪瘟病毒单克隆抗体hk24及医用用途
EP3894867A4 (en) * 2018-12-11 2022-09-28 Merck Sharp & Dohme Corp. PROCEDURE FOR IDENTIFICATION OF HIGH-AFFINITY MONOCLONAL ANTIBODIES OF HEAVY AND LIGHT CHAIN FROM HIGH-THROUGHPUT SCREENS OF B-CELL AND HYBRIDOME LIBRARIES
WO2020246617A1 (ja) * 2019-06-07 2020-12-10 中外製薬株式会社 情報処理システム、情報処理方法、プログラム、及び、抗原結合分子或いはタンパク質を製造する方法
CN110452296A (zh) * 2019-07-16 2019-11-15 福州精锐生物技术有限公司 一种兔单克隆抗体制备方法
MX2022003244A (es) * 2019-09-16 2022-04-26 Regeneron Pharma Metodos de lc-ms para la isotipificacion y cuantificacion de anticuerpos.
EP4074725A4 (en) * 2019-12-09 2024-02-28 Optolane Technologies Inc. SWITCH BINDER, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION, ASSAY KIT, AND METHOD FOR DOSING ANTIGEN AND ANTIBODY, EACH USING THE SAME
WO2021222546A1 (en) * 2020-05-01 2021-11-04 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Compositions and methods for identifying nanobodies and nanobody affinities
CA3214755A1 (en) * 2021-04-09 2022-10-13 Natalie CASTELLANA Method for antibody identification from protein mixtures
IT202100019334A1 (it) * 2021-07-21 2023-01-21 Univ Degli Studi Di Pavia Metodo per l’identificazione dell’intera sequenza della regione variabile delle catene pesanti e leggere di immunoglobuline
CN115894687B (zh) * 2022-03-31 2024-06-07 台州恩泽医疗中心(集团) 一种抗hla-g1,-g2,-g5及hla-g6异构体分子的单克隆抗体及其用途
CN116779037B (zh) * 2022-07-27 2025-08-05 北京理工大学 一种基于从头测序和同源标签图论的抗体序列鉴定方法
CN117849159B (zh) * 2024-01-09 2025-01-07 融智生物科技(青岛)有限公司 M蛋白的检测方法、电子设备及存储介质
CN120214310B (zh) * 2025-05-20 2025-08-19 中国农业大学 一种禽白血病抗原检测试剂盒及其制备方法

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US6548640B1 (en) 1986-03-27 2003-04-15 Btg International Limited Altered antibodies
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6673776B1 (en) 1989-03-21 2004-01-06 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
ATE356869T1 (de) 1990-01-12 2007-04-15 Amgen Fremont Inc Bildung von xenogenen antikörpern
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
WO1993012227A1 (en) 1991-12-17 1993-06-24 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
CA2153692C (en) 1993-01-12 2011-11-08 Roy R. Lobb Recombinant anti-vla4 antibody molecules
US6436908B1 (en) 1995-05-30 2002-08-20 Duke University Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial function
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US5739277A (en) 1995-04-14 1998-04-14 Genentech Inc. Altered polypeptides with increased half-life
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
WO1999018792A1 (en) 1997-10-10 1999-04-22 Johns Hopkins University Gene delivery compositions and methods
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
EP1082458A1 (en) 1998-05-01 2001-03-14 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and dna molecules
US7300753B2 (en) 1998-09-04 2007-11-27 John Rush Immunoaffinity isolation of modified peptides from complex mixtures
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7211390B2 (en) 1999-09-16 2007-05-01 454 Life Sciences Corporation Method of sequencing a nucleic acid
WO2003016861A2 (en) 2001-08-14 2003-02-27 President And Fellows Of Harvard College Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
EP1458736A4 (en) * 2001-12-14 2005-09-14 Lilly Co Eli RECOMBINANT RINDER THROMBIN
GB0130267D0 (en) 2001-12-19 2002-02-06 Neutec Pharma Plc Focussed antibody technology
US7485291B2 (en) 2003-06-03 2009-02-03 Cell Genesys, Inc. Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
CA2526120A1 (en) 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
AU2005211790B2 (en) 2004-02-09 2010-03-11 Northeastern University Monoclonal antibody based biomarker discovery and development platform
EP1718769A4 (en) 2004-02-27 2008-05-14 Harvard College Polonie FLUORESCENCE IN SITU SEQUENZIERKÜGELCHEN
US20070161001A1 (en) 2004-03-04 2007-07-12 Dena Leshkowitz Quantifying and profiling antibody and t cell receptor gene expression
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
AU2006256763B2 (en) * 2005-06-10 2012-08-02 Ares Trading S.A. Process for the purification of IL-18 binding protein
CA2637988A1 (en) 2006-02-10 2007-11-29 Genentech, Inc. Anti-fgf19 antibodies and methods using same
GB0612928D0 (en) 2006-06-29 2006-08-09 Ucb Sa Biological products
WO2008006017A1 (en) * 2006-07-07 2008-01-10 Pall Corporation Use of denaturing agents during affinity capture
US20100015652A1 (en) 2006-12-21 2010-01-21 Brian Walter Granda Antibody quantitation
KR101805140B1 (ko) 2007-03-01 2017-12-05 심포젠 에이/에스 재조합 항-표피 성장 인자 수용체 항체 조성물
WO2008106980A2 (en) * 2007-03-06 2008-09-12 Symphogen A/S Recombinant antibodies for treatment of respiratory syncytial virus infections
HUE041818T2 (hu) 2007-03-22 2019-05-28 Biogen Ma Inc Kötõ proteinek, beleértve az antitesteket, CD154-et specifikusan kötõ antitest származékokat és antitest fragmenseket is, és alkalmazásaik
PT2336329E (pt) 2007-06-01 2012-12-24 Omt Inc Composições e métodos para inibição de genes de imunoglobulina endógena e produção de anticorpos transgénicos humanos idiotípicos
US7887801B2 (en) 2007-07-13 2011-02-15 Topotarget Germany Ag Optimized DNA and protein sequence of an antibody to improve quality and yield of bacterially expressed antibody fusion proteins
EP2220116B1 (en) * 2007-11-12 2012-09-05 Theraclone Sciences, Inc. Compositions and methods for the therapy and diagnosis of influenza
CA2702322A1 (en) * 2007-11-22 2009-05-28 Symphogen A/S A method for characterization of a recombinant polyclonal protein
EP2088432A1 (en) 2008-02-11 2009-08-12 MorphoSys AG Methods for identification of an antibody or a target
WO2010002911A2 (en) 2008-06-30 2010-01-07 H. Lee Moffitt Cancer Center And Research Institute, Inc. Methods and materials for monitoring myeloma using quantitative mass spetrometry
KR101987351B1 (ko) 2008-09-30 2019-06-10 아블렉시스, 엘엘씨 키메라 항체의 제조를 위한 인간 이외의 포유동물
RU2011129459A (ru) 2008-12-18 2013-01-27 Эрасмус Юниверсити Медикал Сентр Роттердам Трансгенные животные (не человек), экспрессирующие гуманизированные антитела, и их применение
US8685898B2 (en) 2009-01-15 2014-04-01 Imdaptive, Inc. Adaptive immunity profiling and methods for generation of monoclonal antibodies
US20110313138A1 (en) 2009-02-25 2011-12-22 Ucb Pharma, S.A. Method for Producing Proteins
PT2564695E (pt) 2009-07-08 2015-06-03 Kymab Ltd Modelos animais e moléculas terapêuticas
US20110045534A1 (en) 2009-08-20 2011-02-24 Cell Signaling Technology, Inc. Nucleic Acid Cassette For Producing Recombinant Antibodies
US8293483B2 (en) 2009-09-11 2012-10-23 Epitomics, Inc. Method for identifying lineage-related antibodies
PL2553100T3 (pl) 2010-03-31 2018-03-30 Ablexis, Llc Inżynieria genetyczna zwierząt nie będących ludźmi w celu wytworzenia przeciwciał chimerycznych
CA2796822C (en) 2010-05-07 2021-10-05 The Board Of Trustees Of The Leland Standford Junior University Measurement and comparison of immune diversity by high-throughput sequencing
CA2799746C (en) * 2010-05-17 2020-11-24 Sai Reddy Rapid isolation of monoclonal antibodies from animals
AU2011266843C9 (en) 2010-06-17 2018-03-01 Kymab Limited Animal models and therapeutic molecules

Also Published As

Publication number Publication date
AU2017245395A2 (en) 2017-11-23
US20120308555A1 (en) 2012-12-06
CN103842379A (zh) 2014-06-04
KR101938343B1 (ko) 2019-01-14
CN108220297A (zh) 2018-06-29
AU2017245395B2 (en) 2019-05-16
HK1256304A1 (en) 2019-09-20
ES2666301T3 (es) 2018-05-03
EP2683736A1 (en) 2014-01-15
JP6211931B2 (ja) 2017-10-11
JP2014509853A (ja) 2014-04-24
AU2012225310A1 (en) 2013-09-26
EP3345922A1 (en) 2018-07-11
WO2012122484A1 (en) 2012-09-13
DK2683736T3 (en) 2018-04-23
AU2017245395A1 (en) 2017-11-02
AU2019216660A1 (en) 2019-09-05
JP2019195335A (ja) 2019-11-14
CA2829606A1 (en) 2012-09-13
AU2012225310B2 (en) 2017-08-03
JP6557709B2 (ja) 2019-08-07
US20190002532A1 (en) 2019-01-03
US9920110B2 (en) 2018-03-20
EP2683736B1 (en) 2018-01-17
JP2018027090A (ja) 2018-02-22
KR20190006083A (ko) 2019-01-16
CA2829606C (en) 2020-06-02
KR20140010436A (ko) 2014-01-24
KR20190107761A (ko) 2019-09-20

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