HUE033204T2 - Factor II alone or in combination with additional factor for the treatment of impaired haemostasis associated with diluted coagulopathy - Google Patents
Factor II alone or in combination with additional factor for the treatment of impaired haemostasis associated with diluted coagulopathy Download PDFInfo
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- HUE033204T2 HUE033204T2 HUE11761051A HUE11761051A HUE033204T2 HU E033204 T2 HUE033204 T2 HU E033204T2 HU E11761051 A HUE11761051 A HU E11761051A HU E11761051 A HUE11761051 A HU E11761051A HU E033204 T2 HUE033204 T2 HU E033204T2
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- obb
- fii
- fibrinogen
- blood
- fviia
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Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Immunology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Hematology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
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|---|---|---|---|
| US39022410P | 2010-10-06 | 2010-10-06 |
Publications (1)
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|---|---|
| HUE033204T2 true HUE033204T2 (en) | 2017-11-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| HUE11761051A HUE033204T2 (en) | 2010-10-06 | 2011-09-19 | Factor II alone or in combination with additional factor for the treatment of impaired haemostasis associated with diluted coagulopathy |
Country Status (16)
| Country | Link |
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| US (1) | US9433664B2 (https=) |
| EP (1) | EP2624859B1 (https=) |
| JP (1) | JP6000259B2 (https=) |
| KR (1) | KR20130136988A (https=) |
| CN (1) | CN103221061A (https=) |
| AU (1) | AU2011313505B2 (https=) |
| BR (1) | BR112013008034A2 (https=) |
| CA (1) | CA2812888A1 (https=) |
| DK (1) | DK2624859T3 (https=) |
| ES (1) | ES2625153T3 (https=) |
| HU (1) | HUE033204T2 (https=) |
| MX (1) | MX343784B (https=) |
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| RU (1) | RU2606155C2 (https=) |
| SG (2) | SG188639A1 (https=) |
| WO (1) | WO2012045569A1 (https=) |
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| US12171463B2 (en) | 2008-10-03 | 2024-12-24 | Femasys Inc. | Contrast agent generation and injection system for sonographic imaging |
| CN103221061A (zh) | 2010-10-06 | 2013-07-24 | 米迪缪尼有限公司 | 用于治疗止血障碍的因子ii以及纤维蛋白原 |
| IL230150A0 (en) * | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing zymogens |
| DK3579857T3 (da) | 2017-02-09 | 2022-06-07 | Csl Behring Gmbh | Et blodkoagulationsfaktorerstatningsprodukt til anvendelse ved behandling eller profylakse af blødninger |
| CN116059431A (zh) * | 2021-10-29 | 2023-05-05 | 丁琴琴 | 一种含凝血因子的双层止血敷料及其制备方法 |
| WO2023220412A1 (en) * | 2022-05-13 | 2023-11-16 | Cedars-Sinai Medical Center | Hemostatic monitor |
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| EP0044343B1 (en) | 1980-01-28 | 1984-08-22 | Baxter Travenol Laboratories, Inc. | Prothrombin-containing therapeutic compositions and methods of producing enzymatically active blood clotting factors from prothrombin-containing blood fractions |
| US4501731A (en) | 1983-06-27 | 1985-02-26 | Tishkoff Garson H | Treatment of disparate bleeding disorders with factor X zymogen |
| DE4430204A1 (de) | 1994-08-26 | 1996-02-29 | Behringwerke Ag | Arzneimittel, welches als Gegenmittel für Blut-Antikoagulanzien geeignet ist und seine Verwendung |
| DK0796623T3 (da) | 1996-03-20 | 2005-08-01 | Baxter Ag | Farmaceutisk præparat til behandling af blodkoagulationslidelser |
| AT409334B (de) | 1997-09-19 | 2002-07-25 | Immuno Ag | Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren |
| US7094428B2 (en) | 2000-06-16 | 2006-08-22 | The University Of Medicine And Dentistry Of New Jersey | Hemostatic compositions, devices and methods |
| US6825323B2 (en) | 2001-01-10 | 2004-11-30 | The United States Of America As Represented By The Secretary Of The Army | Compositions for treatment of hemorrhaging with activated factor VIIa in combination with fibrinogen and methods of using same |
| BR0207007A (pt) | 2001-02-05 | 2004-02-17 | Novo Nordisk Healthcare Ag | Composição farmcêutica, kit, usos de uma preparação e de uma composição, e, métodos para tratar de episódios de hemorragia em um paciente, para reduzir o tempo de coagulação em um paciente, para intensificar a hemostasia em um paciente para reduzir o número de administrações da proteìna do fator de coagulação necessário para deter a hemorragia e manter a hemostasia em um paciente, para reduzir a quantidade de proteìna do fator de coagulação administrada necessária para deter a hemorragia e manter a hemostasia em um paciente, para prolongar o tempo de lise do coágulo em um paciente, para aumentar a resistência do coágulo em paciente e para intensificar a formação de coágulo de fibrina em um paciente |
| US20060025336A1 (en) | 2001-07-16 | 2006-02-02 | Novo Nordisk A/S | Pharmaceutical compositions comprising combinations of factor VII polypeptides and aprotinin polypeptides |
| AU2002354846B2 (en) | 2001-07-20 | 2007-08-02 | Novo Nordisk Health Care Ag | Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides |
| US20040101546A1 (en) * | 2002-11-26 | 2004-05-27 | Gorman Anne Jessica | Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents |
| WO2004060172A1 (en) | 2002-12-31 | 2004-07-22 | Marine Polymer Technologies, Inc. | Hemostatic compositions and uses therefor |
| GB0324044D0 (en) | 2003-10-14 | 2003-11-19 | Astrazeneca Ab | Protein |
| US7211559B2 (en) | 2003-10-31 | 2007-05-01 | University Of Maryland, Baltimore | Factor VIII compositions and methods |
| ES2399277T3 (es) | 2004-05-27 | 2013-03-27 | Baxter International Inc. | Procedimiento de tratamiento de trastornos hemorrágicos utilizando polisacáridos sulfatados |
| WO2006114105A2 (en) | 2005-04-26 | 2006-11-02 | Maxygen Holdings Ltd. | Use of modified factor vii for treating bleeding |
| MX2008006313A (es) | 2005-11-15 | 2008-11-06 | Philadelphia Children Hospital | Metodos y composiciones para modular la hemostasia. |
| WO2007103447A2 (en) * | 2006-03-06 | 2007-09-13 | Humagene, Inc. | A method for the preparation of recombinant human thrombin |
| US20080014251A1 (en) | 2006-07-14 | 2008-01-17 | Advanced Vascular Dynamics | Hemostatic compound and its use |
| US20090148502A1 (en) | 2006-10-23 | 2009-06-11 | Hemo Nanoscience, Llc | Compositions and methods for treating lacerations, abrasions, avulsions, burns, ulcers, and cases of excessive bleeding |
| EP1935429A1 (en) | 2006-12-22 | 2008-06-25 | CSL Behring GmbH | Synergistic therapeutic use of prothrombin complex concentrates with FVIII concentrates |
| AU2008233111A1 (en) | 2007-03-30 | 2008-10-09 | Thrombodyne, Inc. | Methods of making concentrated fibrinogen containing compositions and associated systems for preparing fibrin glue |
| CA2683443A1 (en) | 2007-04-13 | 2008-10-23 | Catalyst Biosciences, Inc. | Modified factor vii polypeptides and uses thereof |
| US8852558B2 (en) | 2008-03-11 | 2014-10-07 | Materials Modification, Inc. | In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst |
| WO2010042741A1 (en) | 2008-10-08 | 2010-04-15 | Thrombodyne, Inc. | Methods of making concentrated fibrinogen- and platelet containing compositions |
| CN103221061A (zh) | 2010-10-06 | 2013-07-24 | 米迪缪尼有限公司 | 用于治疗止血障碍的因子ii以及纤维蛋白原 |
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| WO2012045569A9 (en) | 2016-01-07 |
| CN103221061A (zh) | 2013-07-24 |
| BR112013008034A2 (pt) | 2016-06-14 |
| PL2624859T3 (pl) | 2017-09-29 |
| EP2624859B1 (en) | 2017-03-01 |
| CA2812888A1 (en) | 2012-04-12 |
| JP2013538863A (ja) | 2013-10-17 |
| AU2011313505A1 (en) | 2013-04-11 |
| RU2606155C2 (ru) | 2017-01-10 |
| EP2624859A1 (en) | 2013-08-14 |
| AU2011313505B2 (en) | 2015-09-17 |
| RU2013120033A (ru) | 2014-11-20 |
| DK2624859T3 (en) | 2017-06-06 |
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