HUE031329T2 - Humán növekedési hormon stabil folyékony készítménye - Google Patents

Humán növekedési hormon stabil folyékony készítménye

Info

Publication number
HUE031329T2
HUE031329T2 HUE06769186A HUE06769186A HUE031329T2 HU E031329 T2 HUE031329 T2 HU E031329T2 HU E06769186 A HUE06769186 A HU E06769186A HU E06769186 A HUE06769186 A HU E06769186A HU E031329 T2 HUE031329 T2 HU E031329T2
Authority
HU
Hungary
Prior art keywords
growth hormone
liquid formulation
human growth
stable liquid
stable
Prior art date
Application number
HUE06769186A
Other languages
English (en)
Inventor
Sun Hee Kim
Yo Kyung Chung
Jae Young Chang
Sang Kil Lee
Min Suk Lee
Seung Kook Park
Original Assignee
Daewoong Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daewoong Co Ltd filed Critical Daewoong Co Ltd
Publication of HUE031329T2 publication Critical patent/HUE031329T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH] (Somatotropin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
HUE06769186A 2006-07-06 2006-07-06 Humán növekedési hormon stabil folyékony készítménye HUE031329T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2006/002640 WO2008004717A1 (en) 2006-07-06 2006-07-06 A stable liquid formulation of human growth hormone

Publications (1)

Publication Number Publication Date
HUE031329T2 true HUE031329T2 (hu) 2017-07-28

Family

ID=38894670

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE06769186A HUE031329T2 (hu) 2006-07-06 2006-07-06 Humán növekedési hormon stabil folyékony készítménye

Country Status (11)

Country Link
US (1) US8409586B2 (hu)
EP (1) EP2049148B1 (hu)
JP (1) JP5180202B2 (hu)
CN (1) CN101505789A (hu)
BR (1) BRPI0621841B8 (hu)
ES (1) ES2605022T3 (hu)
HK (1) HK1216992A1 (hu)
HU (1) HUE031329T2 (hu)
LT (1) LT2049148T (hu)
PT (1) PT2049148T (hu)
WO (1) WO2008004717A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011001273A (ja) * 2009-06-16 2011-01-06 Eci Inc eMIPを有効成分とする水溶性製剤
AU2010321225B2 (en) * 2009-11-17 2015-12-03 Ipsen Pharma S.A.S. Formulation for hGH and rhIGF-1 combination
WO2013096835A1 (en) * 2011-12-23 2013-06-27 Abbvie Inc. Stable protein formulations
NZ718960A (en) * 2013-11-12 2017-06-30 Cadila Healthcare Ltd Formulation for gonadotropins
US9908976B2 (en) 2015-03-18 2018-03-06 Psmg, Llc Stable polyethylene glycol particle dispersions and methods for forming the stable dispersions
CN110151988A (zh) * 2018-02-11 2019-08-23 百奥泰生物制药股份有限公司 一种靶向治疗TNF-α相关疾病的人抗体制剂

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61296598A (ja) 1985-06-21 1986-12-27 Mitsubishi Electric Corp Mosダイナミツクramのダミ−ワ−ド線駆動回路
ES2044941T5 (es) * 1987-08-21 1999-02-16 Mallinckrodt Group Inc Estabilizador de hormonas promotoras del crecimiento.
US5981485A (en) 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
ATE359824T1 (de) 1992-07-31 2007-05-15 Genentech Inc Wässrige formulierung enthaltend menschliches wachstumshormon
ZA965368B (en) * 1995-07-14 1997-01-14 Novo Nordisk As A pharmaceutical formulation
KR970006498A (ko) 1995-07-31 1997-02-21 유충식 활성형 인성장호르몬의 정제 방법
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
US20020077461A1 (en) * 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
KR100210840B1 (ko) 1996-12-24 1999-07-15 구본준 기계 화학적 연마 방법 및 그 장치
KR19990001217A (ko) 1997-06-13 1999-01-15 윤종용 스탠바이 모드에서의 시스템 구동방법 및 장치
JP3723857B2 (ja) 1998-02-04 2005-12-07 日本ケミカルリサーチ株式会社 ヒト成長ホルモン含有水性医薬組成物
KR100316347B1 (ko) 1998-09-15 2002-08-27 한미약품(주) 대장균엔테로톡신ⅱ신호펩티드의변형체와인체성장호르몬의융합단백질을발현하는재조합미생물및그를이용한인체성장호르몬의제조방법
KR100573704B1 (ko) 1998-12-02 2006-07-21 동아제약주식회사 인성장 호르몬의 안정화된 액상제제_
HUP0203133A3 (en) * 1999-10-04 2005-07-28 Chiron Corp Emeryville Stabilized liquid polypeptide-containing pharmaceutical compositions
MXPA02003540A (es) 1999-10-08 2003-09-12 Nektar Therapeutics Al Corp Derivados de poli(etilenglicol) heterobifuncionales y los metodos para su preparacion.
US6719992B2 (en) 2000-06-26 2004-04-13 Monsanto Technology Llc Non-aqueous surfactant-containing formulations for extended release of somatotropin
AR040526A1 (es) * 2002-07-09 2005-04-13 Grandis Biotech Gmbh Formulaciuones de hgh en alta concentracion que contienen fenol
WO2004082707A2 (en) * 2003-03-18 2004-09-30 Ares Trading Sa Stabilisation of growth hormones in solution
KR100537260B1 (ko) 2003-09-03 2005-12-19 한미약품 주식회사 인간 성장 호르몬의 안정화된 액상 제제용 조성물
TW200522976A (en) * 2003-09-19 2005-07-16 Novo Nordisk As Novel plasma protein affinity tags
WO2005027960A1 (en) * 2003-09-25 2005-03-31 Cangene Corporation Liquid human growth hormone formulation containing polyethylene glycol
DE10355189B4 (de) 2003-11-26 2015-04-30 Johnson & Johnson Medical Gmbh Verfahren zum Herstellen eines chirurgischen Implantats sowie chirurgisches Implantat
ES2383691T3 (es) 2003-12-23 2012-06-25 Pharmacia Corporation Formulación líquida estable de hormonas de crecimiento

Also Published As

Publication number Publication date
WO2008004717A9 (en) 2013-08-29
CN101505789A (zh) 2009-08-12
ES2605022T3 (es) 2017-03-10
JP5180202B2 (ja) 2013-04-10
HK1216992A1 (zh) 2016-12-16
BRPI0621841A2 (pt) 2011-12-20
PT2049148T (pt) 2016-12-30
JP2009542629A (ja) 2009-12-03
WO2008004717A1 (en) 2008-01-10
US20090298768A1 (en) 2009-12-03
BRPI0621841B1 (pt) 2020-12-29
EP2049148A1 (en) 2009-04-22
US8409586B2 (en) 2013-04-02
EP2049148A4 (en) 2013-12-11
EP2049148B1 (en) 2016-09-28
BRPI0621841B8 (pt) 2021-05-25
LT2049148T (lt) 2016-11-25

Similar Documents

Publication Publication Date Title
HK1216992A1 (zh) 穩定的人生長激素液體製劑
EP2593084A4 (en) LIQUID FORMULATION FROM HUMAN GROWTH HORMONE CONJUGATES WITH LONG-TERM EFFECT
ZA200904544B (en) Stable S-(+)-abscisic acid liquid and soluble granule formulations
EP2081502B8 (en) A medical device for attaching tissue to bone
PL2007356T3 (pl) Preparaty lipopleksowe przeznaczone do swoistego dostarczania do tkanek naczyniowych śródbłonka
HK1181633A1 (en) Endoscopic delivery of medical devices
EP1942981A4 (en) DISTRIBUTION OF MEDIUM TO TISSUE
ZA200900345B (en) Preparation of pharmaceutical formulations
PT1986606T (pt) Formulações líquidas contendo fenilefrina
PL1570866T3 (pl) Sposób dostarczania płynnego środka sterylizującego do sterylizatora
HK1200019A1 (en) Use of a liquid allergy vaccine formulation for oromucosal administration
HK1142536A1 (en) Gel useful for the delivery of cosmetic active ingredients
ZA200900125B (en) Liquid formulation of pyrethroids
ZA200704926B (en) Modified human growth hormone
HK1131546A1 (en) Subcutaneous implants releasing an active principle over an extended period of time
IL213711A (en) Nano-phenofibrate preparation
ZA200809269B (en) Liquid pharmaceutical formulation
EP2073631A4 (en) AGROCHEMICAL FORMULATIONS OF LIQUID CRYSTALS
HK1215930A1 (zh) 穩定的人生長激素液體製劑
IL199756A0 (en) Medically active plaster
GB0813004D0 (en) Stable therapeutic formulation of human growth hormone
HK1144295A1 (en) Stable liquid formulation
GB2451360B (en) Hormone replacement formulation
GB0610207D0 (en) New forms of active pharmaceutical ingredient
ZA200806439B (en) Stable dosage formulations of imidazolylalkyl-pyridines