HUE029264T2 - Pyrazolo-triazine derivatives are selective cyclin-dependent kinase inhibitors - Google Patents

Pyrazolo-triazine derivatives are selective cyclin-dependent kinase inhibitors Download PDF

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Publication number
HUE029264T2
HUE029264T2 HUE13707008A HUE13707008A HUE029264T2 HU E029264 T2 HUE029264 T2 HU E029264T2 HU E13707008 A HUE13707008 A HU E13707008A HU E13707008 A HUE13707008 A HU E13707008A HU E029264 T2 HUE029264 T2 HU E029264T2
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alpha
rti
disease
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HUE13707008A
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Jan Eickhoff
Gunther Zischinsky
Uwe Koch
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Lead Discovery Center Gmbh
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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HUE13707008A 2012-03-01 2013-03-01 Pyrazolo-triazine derivatives are selective cyclin-dependent kinase inhibitors HUE029264T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12157751.4A EP2634190A1 (en) 2012-03-01 2012-03-01 Pyrazolo-triazine derivatives as selective cyclin-dependent kinase inhinitors

Publications (1)

Publication Number Publication Date
HUE029264T2 true HUE029264T2 (en) 2017-02-28

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HUE13707008A HUE029264T2 (en) 2012-03-01 2013-03-01 Pyrazolo-triazine derivatives are selective cyclin-dependent kinase inhibitors

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US (1) US9567345B2 (OSRAM)
EP (2) EP2634190A1 (OSRAM)
JP (1) JP6182549B2 (OSRAM)
KR (1) KR101821452B1 (OSRAM)
CN (1) CN104350054B (OSRAM)
AU (1) AU2013224848B2 (OSRAM)
BR (1) BR112014021189B1 (OSRAM)
CA (1) CA2865946C (OSRAM)
DK (1) DK2820020T3 (OSRAM)
ES (1) ES2583231T3 (OSRAM)
HU (1) HUE029264T2 (OSRAM)
IL (1) IL234183A (OSRAM)
MX (1) MX347359B (OSRAM)
RU (1) RU2645347C2 (OSRAM)
SG (1) SG11201405129RA (OSRAM)
WO (1) WO2013128028A1 (OSRAM)
ZA (1) ZA201406078B (OSRAM)

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EP3664806B1 (en) 2017-08-09 2025-04-30 Sanford Burnham Prebys Medical Discovery Institute 3-PHENYL-PYRAZOLO[1,5-A]PYRIMIDINE-5-CARBOXILIC ACID DERIVATIVES AS APELIN (APJ) RECEPTOR AGONISTS FOR THE TREATMENT OF CARDIOVASCULAR, METABOLIC, CNS, OR INFECTIOUS DISEASES OR DISORDERS
GB201715194D0 (en) 2017-09-20 2017-11-01 Carrick Therapeutics Ltd Compounds and their therapeutic use
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US11945822B2 (en) * 2018-04-11 2024-04-02 Qurient Co., Ltd. Pyrazolo-triazine and/or pyrazolo-pxrimidine derivatives as selective inhibitor of cyclin dependent kinase
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US11517568B2 (en) 2018-09-12 2022-12-06 The Governing Council Of The University Of Toronto Compounds and methods for treating nematode infections
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CN110101703B (zh) * 2019-05-06 2021-06-11 暨南大学 Cdk7抑制剂在制备溃疡性结肠炎或结肠癌药物的应用
RU2713152C1 (ru) * 2019-08-30 2020-02-04 Федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ лечения хронической аллергической крапивницы на фоне описторхоза
TW202146416A (zh) * 2019-12-11 2021-12-16 德商拜耳廠股份有限公司 吡唑并三𠯤
GB201918541D0 (en) * 2019-12-16 2020-01-29 Carrick Therapeutics Ltd Therapeutic compounds and their use
CN110950871B (zh) * 2019-12-25 2022-05-17 陕西师范大学 2-取代-4-芳氨基吡唑并三嗪衍生物及制备抗肿瘤药物的应用
WO2022136174A1 (en) * 2020-12-21 2022-06-30 Janssen Pharmaceutica Nv Tricyclic pyrimidines as cyclin-dependent kinase 7 (cdk7) inhibitors
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CA2865946A1 (en) 2013-09-06
WO2013128028A1 (en) 2013-09-06
RU2645347C2 (ru) 2018-02-21
KR101821452B1 (ko) 2018-01-23
BR112014021189A2 (OSRAM) 2017-06-20
CA2865946C (en) 2020-01-21
SG11201405129RA (en) 2014-09-26
WO2013128028A8 (en) 2014-10-02
DK2820020T3 (en) 2016-07-04
US20150018329A1 (en) 2015-01-15
KR20140131994A (ko) 2014-11-14
JP2015511952A (ja) 2015-04-23
HK1206014A1 (en) 2015-12-31
BR112014021189B1 (pt) 2022-08-16
EP2634190A1 (en) 2013-09-04
AU2013224848A1 (en) 2014-08-28
EP2820020A1 (en) 2015-01-07
ZA201406078B (en) 2016-08-31
US9567345B2 (en) 2017-02-14
AU2013224848B2 (en) 2017-06-29
CN104350054B (zh) 2017-06-13
MX2014010494A (es) 2015-04-08
MX347359B (es) 2017-04-06
ES2583231T3 (es) 2016-09-19
RU2014139705A (ru) 2016-04-20
JP6182549B2 (ja) 2017-08-16
CN104350054A (zh) 2015-02-11
EP2820020B1 (en) 2016-04-06
IL234183A (en) 2016-11-30

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