HUE028740T2 - Gyógyászati készítmény mometazon-furoáttal és azelasztin-hidrokloriddal nazális adagolásra - Google Patents

Gyógyászati készítmény mometazon-furoáttal és azelasztin-hidrokloriddal nazális adagolásra Download PDF

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Publication number
HUE028740T2
HUE028740T2 HUE11845222A HUE11845222A HUE028740T2 HU E028740 T2 HUE028740 T2 HU E028740T2 HU E11845222 A HUE11845222 A HU E11845222A HU E11845222 A HUE11845222 A HU E11845222A HU E028740 T2 HUE028740 T2 HU E028740T2
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HU
Hungary
Prior art keywords
pharmaceutical composition
nasal administration
nasal
volume
sodium
Prior art date
Application number
HUE11845222A
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English (en)
Inventor
Sang-Yong Lee
Geun-Hyeog Lee
Byong-Sun Choi
Jong-Hyeon Ryu
Jin-Ha Park
Mi-Jin O
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Hanlim Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hanlim Pharmaceutical Co Ltd filed Critical Hanlim Pharmaceutical Co Ltd
Publication of HUE028740T2 publication Critical patent/HUE028740T2/hu

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (6)

Gyógyibsatl készítmény m ome tazo» ~tb reálta 1 és az.elasztliV'ydrc.tóöriddal nazális Szabadalmi ígédy^»fok
1, Gyógyászati készítmény nazális adagol ásra* tóornetazon-ldojátí és azelasztin-hidrokíoriddai, Äl'i a gyógyászati lészftmény a kesérl ízt és Irritáeiot csókként# szerként tan-malmi tartalmaz.
2, Az I. igénypont sztóntl gyópaszaiíkészítmény nazális adagolásra, ától a fomoaün 0,1-0,5 sálydérlbgat % ntennpségben van Jelen.
3, Az I > Igénypont szerinti gyógyászati készítmény nazális adagolásra, ahol a gyógyászati készítmény 0,01-1 J söly/térfogat % raomstazon-tonatot; §,05-1,0 sóíy/téríbgaí % azeíasztín-líMreklöfídoí; 0.1-0,5 sólyAérfogái % tmnnatlni; 1,0-:5,0 sniy/forfogat % sirkőszert; #,2-0,6 sóly/térfogai % pnffer anyagot; 0,001-0,1 súiy/térfogat % felületaktív anyagét- 5,§-i0,O: sify/téríbgat % izetómás szert; 0,01-1,11 sűly/térlbgai % stabllzátort és 0,002-0,05 snly/térlbgat % tartósiószert tartalmaz vizes kózegtóm
4, A 3. igénypont szerinti gyógyászati készítmény nazális adagolásra, ahol a gyógyászati készítmény 0,01-1# sIlyAérfogat % mometazon-lhroátot; 0,05-1,0 snly/térlogat % azeíaszíín-hldrokferidoi; 0,Í-0J snly/iétfogai % taumatint; 1,0-5,0 siÍ$$Mefái: %· cellélóz és nátrióm-tórtel-ntetll-eelfulóz keveréket; 0,2-0,6 súly/térfogat 3¾ citrorasav és nátniím-eitíit keveréket; 0,001-0,1 snîÿ/tér fogai % poll(ozl-etlién:)-szorhltân-monôoleâîot; 5,0-10,0 sólyrtértogat "% glicerin és szerbi eíegyei; 0,01-1,0 sníyÉÉrfepi % nátrtum-edeíátoi és 0,0O2-0;05 sély/térfogat % benzalkóniora-kíntidot tartalmaz vizes közegben.
5, A 4, Igénypont szerinti gyógyászati készítmény nazális adagolásra, ahol a gyógyászati készítmény 0#S sniy/íériogat % mometazon-fhroáttól; 0,14 snly/térlbgat % azglasztln-hldrokloridtól; 0,25 sniy/tiribgat % taanratintól; 2,0 snly/térfept % mikrokristályos oellólóz és náfelnm-karboxómotii-eelfelóz elegyhol; 0# snly/térfogat % citromsavtói; 0,2S sóiy/térfegat % aátrinm^eitráiból; 0,0 í suly/térfopt % poltíoxl-etllin)~szorhittó-monoöfeátbók 2,1 súly/térfbgal % glicerinből; 6,ë súly/térfogat % szófiáiból; 0,1 sûiy/ïéribgsî % nátónm^edetátból.;: 0,02 súly/tárfbgaí % benzalkéní-um-kioridból : és & fmmmmâéê mennyiségig viaMl áll.
6. Az .1 .-5. igénypont bármelyike sæmnîi gyógyászati készítmény nazális adagolásra, ahol a gyógyászati készítményt nazális spray lomtára ármoláljak.
HUE11845222A 2010-11-29 2011-11-18 Gyógyászati készítmény mometazon-furoáttal és azelasztin-hidrokloriddal nazális adagolásra HUE028740T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020100119632A KR101261230B1 (ko) 2010-11-29 2010-11-29 모메타손 푸로에이트 및 아젤라스틴 염산염을 포함하는 비내 투여용 약학 조성물

Publications (1)

Publication Number Publication Date
HUE028740T2 true HUE028740T2 (hu) 2016-12-28

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HUE11845222A HUE028740T2 (hu) 2010-11-29 2011-11-18 Gyógyászati készítmény mometazon-furoáttal és azelasztin-hidrokloriddal nazális adagolásra

Country Status (10)

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US (1) US8859531B2 (hu)
EP (1) EP2647380B1 (hu)
JP (1) JP5775597B2 (hu)
KR (1) KR101261230B1 (hu)
CN (1) CN103237550B (hu)
BR (1) BR112013012587A2 (hu)
HU (1) HUE028740T2 (hu)
RU (1) RU2563115C2 (hu)
UA (1) UA111343C2 (hu)
WO (1) WO2012074231A2 (hu)

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BR112015023328A2 (pt) 2013-03-13 2017-07-18 Flatley Discovery Lab compostos de piridazinona e métodos para o tratamento de fibrose cística
WO2015036902A1 (en) 2013-09-13 2015-03-19 Glenmark Pharmaceuticals Ltd Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
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CA3002384C (en) * 2015-10-25 2021-02-16 Iview Therapeutics, Inc. Pharmaceutical formulations that form gel in situ
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JP6941889B2 (ja) 2017-09-02 2021-09-29 アイビュー セラピューティクス、インコーポレイテッド インサイチュゲル形成医薬組成物および副鼻腔疾患のためのその使用
CN107737105A (zh) * 2017-11-28 2018-02-27 贵州云峰药业有限公司 一种鼻腔用盐酸氮卓斯汀组合物喷雾剂及生产工艺
US11389458B2 (en) 2019-04-12 2022-07-19 LA PharmaTech Inc. Pharmaceutical compositions and methods for treating parkinson's and huntington's disease
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WO2022035388A1 (en) * 2020-08-14 2022-02-17 Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. Pharmaceutical compositions comprising azelastine and relevant excipients
WO2022098319A1 (en) * 2020-11-09 2022-05-12 Pharmactive Ilac Sanayi Ve Ticarey A.S. Pharmaceutical compositions comprising azelastine, beclomethasone and relevant excipients
US11351179B1 (en) 2021-08-05 2022-06-07 LA PharmaTech Inc. Pharmaceutical compositions and methods for treatment of psychiatric disorders
WO2023014361A1 (en) * 2021-08-05 2023-02-09 La Pharma Tech Inc. Novel pharmaceutical compositions and methods for treatment of psychiatric disorders
WO2024079676A1 (en) * 2022-10-12 2024-04-18 Glenmark Specialty S.A. Novel nasal spray assembling process

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Also Published As

Publication number Publication date
UA111343C2 (uk) 2016-04-25
JP2013543889A (ja) 2013-12-09
CN103237550A (zh) 2013-08-07
JP5775597B2 (ja) 2015-09-09
CN103237550B (zh) 2016-05-18
EP2647380A4 (en) 2015-03-11
WO2012074231A3 (ko) 2012-07-19
KR101261230B1 (ko) 2013-05-07
KR20120058029A (ko) 2012-06-07
WO2012074231A2 (ko) 2012-06-07
RU2013124024A (ru) 2015-01-10
EP2647380B1 (en) 2016-02-03
RU2563115C2 (ru) 2015-09-20
US8859531B2 (en) 2014-10-14
EP2647380A2 (en) 2013-10-09
BR112013012587A2 (pt) 2016-09-06
US20130252929A1 (en) 2013-09-26

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