HUE028671T2 - Stable tiacumicin compositions - Google Patents
Stable tiacumicin compositions Download PDFInfo
- Publication number
- HUE028671T2 HUE028671T2 HUE08724557A HUE08724557A HUE028671T2 HU E028671 T2 HUE028671 T2 HU E028671T2 HU E08724557 A HUE08724557 A HU E08724557A HU E08724557 A HUE08724557 A HU E08724557A HU E028671 T2 HUE028671 T2 HU E028671T2
- Authority
- HU
- Hungary
- Prior art keywords
- composition
- difimicin
- pharmaceutical
- related compound
- starch
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims description 92
- 229930187202 Tiacumicin Natural products 0.000 title description 14
- 239000008194 pharmaceutical composition Substances 0.000 claims description 31
- 208000015181 infectious disease Diseases 0.000 claims description 22
- 206010012735 Diarrhoea Diseases 0.000 claims description 17
- 229920002472 Starch Polymers 0.000 claims description 13
- 235000019698 starch Nutrition 0.000 claims description 13
- 201000010099 disease Diseases 0.000 claims description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 11
- 239000007909 solid dosage form Substances 0.000 claims description 11
- 239000008107 starch Substances 0.000 claims description 11
- 230000003115 biocidal effect Effects 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
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- 239000007787 solid Substances 0.000 claims description 5
- 206010028980 Neoplasm Diseases 0.000 claims description 4
- 201000011510 cancer Diseases 0.000 claims description 4
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- 238000002560 therapeutic procedure Methods 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
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- XFKOEOXSKIWGAR-UHFFFAOYSA-N octadecanoic acid;phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O.CCCCCCCCCCCCCCCCCC(O)=O XFKOEOXSKIWGAR-UHFFFAOYSA-N 0.000 claims 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Virology (AREA)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
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| US88113707P | 2007-01-19 | 2007-01-19 |
Publications (1)
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| HUE028671T2 true HUE028671T2 (en) | 2016-12-28 |
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| HUE08724557A HUE028671T2 (en) | 2007-01-19 | 2008-01-17 | Stable tiacumicin compositions |
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| HR (1) | HRP20151438T1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7906489B2 (en) | 2004-05-14 | 2011-03-15 | Optimer Pharmaceuticals, Inc. | 18-membered macrocycles and analogs thereof |
| US7378508B2 (en) | 2007-01-22 | 2008-05-27 | Optimer Pharmaceuticals, Inc. | Polymorphic crystalline forms of tiacumicin B |
| TWI523654B (zh) | 2007-11-27 | 2016-03-01 | 默沙東藥廠 | 抗生素巨環化合物以及其製造及使用之方法 |
| CA2799531A1 (en) * | 2010-05-18 | 2011-11-24 | Optimer Pharmaceuticals, Inc. | Treating recurring clostridium difficile infection using fidaxomicin |
| CA2799386A1 (en) * | 2010-05-18 | 2011-11-24 | Optimer Pharmaceuticals, Inc. | Treatment of clostridium difficile infection in patients undergoing antibiotic therapy |
| EP2575487B1 (en) * | 2010-06-02 | 2017-10-18 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
| WO2012106722A2 (en) * | 2011-02-04 | 2012-08-09 | Optimer Pharmaceuticals, Inc. | Treatment of bacterial infections |
| ITMI20120560A1 (it) | 2012-04-05 | 2013-10-06 | Olon Spa | Procedimento per la purificazione della tiacumicina b |
| JO3464B1 (ar) * | 2013-01-15 | 2020-07-05 | Astellas Pharma Europe Ltd | التركيبات الخاصة بمركبات التياكوميسين |
| US20150141356A1 (en) * | 2013-11-15 | 2015-05-21 | Optimer Pharmaceuticals, Inc. | Treatment of Clostridium Difficile Infection in High Risk Patients |
| WO2015127955A1 (en) | 2014-02-25 | 2015-09-03 | Olon S.P.A. | A new polymorph of tiacumicin b and process for preparation thereof |
| DK3139932T3 (en) * | 2014-05-09 | 2018-11-12 | Astellas Pharma Europe Ltd | The treatment regimen for thiacumicin compound |
| CN110037992B (zh) * | 2019-05-28 | 2021-05-28 | 杭州华东医药集团新药研究院有限公司 | 一种稳定的非达霉素组合物 |
| CN112353774B (zh) * | 2020-11-17 | 2022-08-23 | 浙江汇能生物股份有限公司 | 一种那西肽风味咀嚼片及其制备方法及其在犬魏氏梭菌病上的用途 |
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| JPH05192094A (ja) * | 1991-09-03 | 1993-08-03 | Takeda Chem Ind Ltd | 造粒組成物 |
| US5583115A (en) * | 1995-05-09 | 1996-12-10 | Abbott Laboratories | Dialkyltiacumicin compounds |
| AU2001211213A1 (en) * | 2000-10-20 | 2002-04-29 | Galephar M/F | Stable oral formulation containing benzimidazole derivative |
| US20030099699A1 (en) * | 2001-11-13 | 2003-05-29 | Hanshew Dwight D. | Storage stable thyroxine active drug formulations and methods for their production |
| US7507564B2 (en) * | 2002-07-29 | 2009-03-24 | Optimer Pharmaceuticals, Inc. | Tiacumicin production |
| US9211259B2 (en) * | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US20040224020A1 (en) * | 2002-12-18 | 2004-11-11 | Schoenhard Grant L. | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
| US7906489B2 (en) * | 2004-05-14 | 2011-03-15 | Optimer Pharmaceuticals, Inc. | 18-membered macrocycles and analogs thereof |
| CA2596387C (en) * | 2005-01-31 | 2012-11-20 | Optimer Pharmaceuticals, Inc. | 18-membered macrocycles and analogs thereof |
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2008
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- 2008-01-17 WO PCT/US2008/000591 patent/WO2008091518A1/en not_active Ceased
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- 2008-01-17 ES ES08724557.7T patent/ES2560669T3/es active Active
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- 2008-01-17 DK DK08724557.7T patent/DK2121716T3/en active
- 2008-01-17 KR KR1020097017319A patent/KR101491729B1/ko not_active Expired - Fee Related
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2009
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2012
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2014
- 2014-06-24 JP JP2014129106A patent/JP5995331B2/ja active Active
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2016
- 2016-03-01 CY CY20161100177T patent/CY1117237T1/el unknown
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