HUE028615T2 - Treatment of osteoarthritis - Google Patents
Treatment of osteoarthritis Download PDFInfo
- Publication number
- HUE028615T2 HUE028615T2 HUE09833924A HUE09833924A HUE028615T2 HU E028615 T2 HUE028615 T2 HU E028615T2 HU E09833924 A HUE09833924 A HU E09833924A HU E09833924 A HUE09833924 A HU E09833924A HU E028615 T2 HUE028615 T2 HU E028615T2
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- Prior art keywords
- antibody
- csf
- ser
- seq
- leu
- Prior art date
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Classifications
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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Landscapes
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- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
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| US13967908P | 2008-12-22 | 2008-12-22 | |
| US16448609P | 2009-03-30 | 2009-03-30 |
Publications (1)
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| HUE028615T2 true HUE028615T2 (en) | 2016-12-28 |
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| HUE09833924A HUE028615T2 (en) | 2008-12-22 | 2009-12-21 | Treatment of osteoarthritis |
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| EP (2) | EP3056217B1 (OSRAM) |
| JP (3) | JP5727379B2 (OSRAM) |
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| BR (1) | BRPI0918356B1 (OSRAM) |
| CA (1) | CA2746827C (OSRAM) |
| CY (1) | CY1117698T1 (OSRAM) |
| DK (1) | DK2376121T4 (OSRAM) |
| ES (2) | ES2572368T5 (OSRAM) |
| HK (1) | HK1226938A1 (OSRAM) |
| HR (1) | HRP20160577T4 (OSRAM) |
| HU (1) | HUE028615T2 (OSRAM) |
| PL (1) | PL2376121T5 (OSRAM) |
| RU (2) | RU2011127334A (OSRAM) |
| SI (2) | SI2376121T1 (OSRAM) |
| SM (1) | SMT201600156B (OSRAM) |
| WO (1) | WO2010071924A1 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3056217B1 (en) | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| KR101761324B1 (ko) | 2008-12-22 | 2017-07-25 | 더 유니버시티 오브 멜버른 | 통증 치료 |
| KR20150056846A (ko) | 2012-09-20 | 2015-05-27 | 모르포시스 아게 | 류마티스 관절염에 대한 치료 |
| DE102013222200A1 (de) * | 2013-10-31 | 2015-08-27 | Osram Opto Semiconductors Gmbh | Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements |
| KR20200054171A (ko) * | 2017-08-14 | 2020-05-19 | 지네르바 파마슈티컬스, 인코포레이티드 | 경피 칸나비디올 겔을 이용한 골관절염의 치료 방법 |
| WO2020104833A1 (en) * | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN110075304B (zh) * | 2019-05-29 | 2020-02-11 | 四川大学华西医院 | 一种治疗骨关节炎的药物组合物及其用途 |
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| AU630496B2 (en) | 1989-07-14 | 1992-10-29 | Schering Corporation | Antagonists of gm-csf derived from the carboxyl terminus |
| EP0486572B1 (en) | 1989-08-11 | 1998-01-07 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| US5747032A (en) | 1990-08-10 | 1998-05-05 | Amrad Corporation Limited | Monoclonal antibody to human granulocyte macrophage colony stimulating factor |
| WO1994011404A1 (en) | 1992-11-19 | 1994-05-26 | Dana-Farber Cancer Institute | Antibodies for gm-csf receptor and uses thereof |
| ES2176484T3 (es) | 1995-08-18 | 2002-12-01 | Morphosys Ag | Bancos de proteinas/(poli)peptidos. |
| AUPP525198A0 (en) | 1998-08-13 | 1998-09-03 | Medvet Science Pty. Ltd. | Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof |
| US7108852B2 (en) | 2000-03-20 | 2006-09-19 | Warner-Lambert Company Llc | Methods of treating inflammation using antibodies to M-CSF |
| US7455836B2 (en) | 2000-05-08 | 2008-11-25 | The University Of Melbourne | Method of treatment and agents useful for same |
| AU2002346882A1 (en) * | 2001-10-26 | 2003-05-06 | Novartis Ag | Methods for the treatment of osteoarthritis and compositions thereof |
| ES2365606T3 (es) | 2002-02-13 | 2011-10-07 | Ludwig Institute For Cancer Research Ltd. | Anticuerpos contra gm-csf quiméricos. |
| US20040241755A1 (en) * | 2003-06-02 | 2004-12-02 | Pfizer Inc. | Human cell assay to determine effect of sample compounds on Col2 enhancer expression |
| ES2341461T5 (es) | 2004-02-11 | 2014-10-29 | Warner-Lambert Company Llc | Procedimientos de tratamiento de la artrosis con anticuerpos ANTI-IL-6 |
| JP4825667B2 (ja) * | 2004-03-31 | 2011-11-30 | 一和 中尾 | 関節炎症治療剤又は予防剤 |
| EP1593690B1 (en) | 2004-05-05 | 2009-07-01 | Micromet AG | Preparation of ScFv antibody fragments |
| WO2006023412A2 (en) | 2004-08-18 | 2006-03-02 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Biomarkers for osteoarthritis |
| US20060040258A1 (en) | 2004-08-23 | 2006-02-23 | Huiyan Guo | Water-soluble conjugates and methods of preparation |
| EP1874819B1 (en) | 2005-04-18 | 2015-05-27 | Amgen Research (Munich) GmbH | Antibody neutralizers of human granulocyte macrophage colony stimulating factor |
| HUE058876T2 (hu) * | 2005-05-18 | 2022-09-28 | Morphosys Ag | Anti-GM-CSF antitestek és felhasználásuk |
| JP4736037B2 (ja) | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| CA2629850A1 (en) * | 2005-12-01 | 2007-06-07 | Domantis Limited | Competitive domain antibody formats that bind interleukin 1 receptor type 1 |
| ES2609088T3 (es) * | 2006-02-08 | 2017-04-18 | Morphotek, Inc. | Péptidos GM-CSF antigénicos y anticuerpos anti-GM-CSF |
| RU2495050C2 (ru) * | 2006-03-27 | 2013-10-10 | Медимьюн Лимитед | Связующий элемент для рецептора gm-csf |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US20080206241A1 (en) * | 2006-11-21 | 2008-08-28 | Kalobios Pharmaceuticals Inc. | Methods of Treating Chronic Inflammatory Diseases Using a GM-CSF Antagonist |
| WO2008080134A2 (en) * | 2006-12-22 | 2008-07-03 | Rigel Pharmaceuticals, Inc. | 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors |
| EP2160407A4 (en) * | 2007-05-23 | 2011-07-27 | Crc For Asthma And Airways Ltd | NEUTRALIZING ANTIBODIES |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| WO2009042854A1 (en) * | 2007-09-26 | 2009-04-02 | Musculoskeletal Research Llc | Ion-channel regulator compositions and methods of using same |
| US20100297135A1 (en) | 2007-11-12 | 2010-11-25 | Crc For Asthma And Airways Ltd. | Epitope for neutralizing antibodies |
| PT2215119E (pt) * | 2007-11-13 | 2013-02-11 | Boehringer Ingelheim Int | Anticorpos monoclonais que se ligam a hgm-csf e composições médicas que os compreendem |
| EP2271671A2 (en) | 2008-03-24 | 2011-01-12 | Abbott Biotechnology Ltd. | Tnf-alpha inhibitors for treating bone loss |
| AU2009243184B2 (en) * | 2008-04-28 | 2015-06-04 | Humanigen, Inc. | Antibodies to granulocyte-macrophage colony-stimulating factor |
| EP3056217B1 (en) | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| KR101761324B1 (ko) | 2008-12-22 | 2017-07-25 | 더 유니버시티 오브 멜버른 | 통증 치료 |
| CA2759506A1 (en) | 2009-04-23 | 2010-10-28 | Theraclone Sciences, Inc. | Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies |
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2009
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- 2009-12-21 US US13/140,467 patent/US9243061B2/en active Active
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- 2009-12-21 KR KR1020177032850A patent/KR101898982B1/ko active Active
- 2009-12-21 WO PCT/AU2009/001672 patent/WO2010071924A1/en not_active Ceased
- 2009-12-21 CN CN201610822096.9A patent/CN106397591A/zh active Pending
- 2009-12-21 SI SI200931446A patent/SI2376121T1/sl unknown
- 2009-12-21 KR KR1020117017015A patent/KR101799264B1/ko active Active
- 2009-12-21 PL PL09833924T patent/PL2376121T5/pl unknown
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- 2009-12-21 BR BRPI0918356-6A patent/BRPI0918356B1/pt active IP Right Grant
- 2009-12-21 RU RU2016102339A patent/RU2712273C2/ru active
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