ES2572368T5 - Tratamiento de la artrosis - Google Patents
Tratamiento de la artrosis Download PDFInfo
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- ES2572368T5 ES2572368T5 ES09833924T ES09833924T ES2572368T5 ES 2572368 T5 ES2572368 T5 ES 2572368T5 ES 09833924 T ES09833924 T ES 09833924T ES 09833924 T ES09833924 T ES 09833924T ES 2572368 T5 ES2572368 T5 ES 2572368T5
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- osteoarthritis
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Polarising Elements (AREA)
- Glass Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13967908P | 2008-12-22 | 2008-12-22 | |
| US16448609P | 2009-03-30 | 2009-03-30 | |
| PCT/AU2009/001672 WO2010071924A1 (en) | 2008-12-22 | 2009-12-21 | Osteoarthritis treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2572368T3 ES2572368T3 (es) | 2016-05-31 |
| ES2572368T5 true ES2572368T5 (es) | 2021-12-16 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09833924T Active ES2572368T5 (es) | 2008-12-22 | 2009-12-21 | Tratamiento de la artrosis |
| ES15194091T Active ES2886063T3 (es) | 2008-12-22 | 2009-12-21 | Tratamiento de la artrosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15194091T Active ES2886063T3 (es) | 2008-12-22 | 2009-12-21 | Tratamiento de la artrosis |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9243061B2 (OSRAM) |
| EP (2) | EP3056217B1 (OSRAM) |
| JP (3) | JP5727379B2 (OSRAM) |
| KR (2) | KR101898982B1 (OSRAM) |
| CN (2) | CN106397591A (OSRAM) |
| AU (1) | AU2009329814B2 (OSRAM) |
| BR (1) | BRPI0918356B1 (OSRAM) |
| CA (1) | CA2746827C (OSRAM) |
| CY (1) | CY1117698T1 (OSRAM) |
| DK (1) | DK2376121T4 (OSRAM) |
| ES (2) | ES2572368T5 (OSRAM) |
| HK (1) | HK1226938A1 (OSRAM) |
| HR (1) | HRP20160577T4 (OSRAM) |
| HU (1) | HUE028615T2 (OSRAM) |
| PL (1) | PL2376121T5 (OSRAM) |
| RU (2) | RU2011127334A (OSRAM) |
| SI (2) | SI2376121T1 (OSRAM) |
| SM (1) | SMT201600156B (OSRAM) |
| WO (1) | WO2010071924A1 (OSRAM) |
Families Citing this family (7)
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| EP3056217B1 (en) | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| KR101761324B1 (ko) | 2008-12-22 | 2017-07-25 | 더 유니버시티 오브 멜버른 | 통증 치료 |
| KR20150056846A (ko) | 2012-09-20 | 2015-05-27 | 모르포시스 아게 | 류마티스 관절염에 대한 치료 |
| DE102013222200A1 (de) * | 2013-10-31 | 2015-08-27 | Osram Opto Semiconductors Gmbh | Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements |
| KR20200054171A (ko) * | 2017-08-14 | 2020-05-19 | 지네르바 파마슈티컬스, 인코포레이티드 | 경피 칸나비디올 겔을 이용한 골관절염의 치료 방법 |
| WO2020104833A1 (en) * | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN110075304B (zh) * | 2019-05-29 | 2020-02-11 | 四川大学华西医院 | 一种治疗骨关节炎的药物组合物及其用途 |
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| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| AU630496B2 (en) | 1989-07-14 | 1992-10-29 | Schering Corporation | Antagonists of gm-csf derived from the carboxyl terminus |
| EP0486572B1 (en) | 1989-08-11 | 1998-01-07 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| US5747032A (en) | 1990-08-10 | 1998-05-05 | Amrad Corporation Limited | Monoclonal antibody to human granulocyte macrophage colony stimulating factor |
| WO1994011404A1 (en) | 1992-11-19 | 1994-05-26 | Dana-Farber Cancer Institute | Antibodies for gm-csf receptor and uses thereof |
| ES2176484T3 (es) | 1995-08-18 | 2002-12-01 | Morphosys Ag | Bancos de proteinas/(poli)peptidos. |
| AUPP525198A0 (en) | 1998-08-13 | 1998-09-03 | Medvet Science Pty. Ltd. | Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof |
| US7108852B2 (en) | 2000-03-20 | 2006-09-19 | Warner-Lambert Company Llc | Methods of treating inflammation using antibodies to M-CSF |
| US7455836B2 (en) | 2000-05-08 | 2008-11-25 | The University Of Melbourne | Method of treatment and agents useful for same |
| AU2002346882A1 (en) * | 2001-10-26 | 2003-05-06 | Novartis Ag | Methods for the treatment of osteoarthritis and compositions thereof |
| ES2365606T3 (es) | 2002-02-13 | 2011-10-07 | Ludwig Institute For Cancer Research Ltd. | Anticuerpos contra gm-csf quiméricos. |
| US20040241755A1 (en) * | 2003-06-02 | 2004-12-02 | Pfizer Inc. | Human cell assay to determine effect of sample compounds on Col2 enhancer expression |
| ES2341461T5 (es) | 2004-02-11 | 2014-10-29 | Warner-Lambert Company Llc | Procedimientos de tratamiento de la artrosis con anticuerpos ANTI-IL-6 |
| JP4825667B2 (ja) * | 2004-03-31 | 2011-11-30 | 一和 中尾 | 関節炎症治療剤又は予防剤 |
| EP1593690B1 (en) | 2004-05-05 | 2009-07-01 | Micromet AG | Preparation of ScFv antibody fragments |
| WO2006023412A2 (en) | 2004-08-18 | 2006-03-02 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Biomarkers for osteoarthritis |
| US20060040258A1 (en) | 2004-08-23 | 2006-02-23 | Huiyan Guo | Water-soluble conjugates and methods of preparation |
| EP1874819B1 (en) | 2005-04-18 | 2015-05-27 | Amgen Research (Munich) GmbH | Antibody neutralizers of human granulocyte macrophage colony stimulating factor |
| HUE058876T2 (hu) * | 2005-05-18 | 2022-09-28 | Morphosys Ag | Anti-GM-CSF antitestek és felhasználásuk |
| JP4736037B2 (ja) | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| CA2629850A1 (en) * | 2005-12-01 | 2007-06-07 | Domantis Limited | Competitive domain antibody formats that bind interleukin 1 receptor type 1 |
| ES2609088T3 (es) * | 2006-02-08 | 2017-04-18 | Morphotek, Inc. | Péptidos GM-CSF antigénicos y anticuerpos anti-GM-CSF |
| RU2495050C2 (ru) * | 2006-03-27 | 2013-10-10 | Медимьюн Лимитед | Связующий элемент для рецептора gm-csf |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US20080206241A1 (en) * | 2006-11-21 | 2008-08-28 | Kalobios Pharmaceuticals Inc. | Methods of Treating Chronic Inflammatory Diseases Using a GM-CSF Antagonist |
| WO2008080134A2 (en) * | 2006-12-22 | 2008-07-03 | Rigel Pharmaceuticals, Inc. | 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors |
| EP2160407A4 (en) * | 2007-05-23 | 2011-07-27 | Crc For Asthma And Airways Ltd | NEUTRALIZING ANTIBODIES |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| WO2009042854A1 (en) * | 2007-09-26 | 2009-04-02 | Musculoskeletal Research Llc | Ion-channel regulator compositions and methods of using same |
| US20100297135A1 (en) | 2007-11-12 | 2010-11-25 | Crc For Asthma And Airways Ltd. | Epitope for neutralizing antibodies |
| PT2215119E (pt) * | 2007-11-13 | 2013-02-11 | Boehringer Ingelheim Int | Anticorpos monoclonais que se ligam a hgm-csf e composições médicas que os compreendem |
| EP2271671A2 (en) | 2008-03-24 | 2011-01-12 | Abbott Biotechnology Ltd. | Tnf-alpha inhibitors for treating bone loss |
| AU2009243184B2 (en) * | 2008-04-28 | 2015-06-04 | Humanigen, Inc. | Antibodies to granulocyte-macrophage colony-stimulating factor |
| EP3056217B1 (en) | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| KR101761324B1 (ko) | 2008-12-22 | 2017-07-25 | 더 유니버시티 오브 멜버른 | 통증 치료 |
| CA2759506A1 (en) | 2009-04-23 | 2010-10-28 | Theraclone Sciences, Inc. | Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies |
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2009
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- 2009-12-21 ES ES15194091T patent/ES2886063T3/es active Active
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2015
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2016
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2017
- 2017-06-12 JP JP2017114806A patent/JP6458086B2/ja active Active
- 2017-11-13 US US15/811,279 patent/US20180066062A1/en not_active Abandoned
-
2020
- 2020-03-31 US US16/836,464 patent/US20200247895A1/en not_active Abandoned
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