HUE028082T2 - Heterocyclic compounds useful as pdk1 inhibitors - Google Patents

Heterocyclic compounds useful as pdk1 inhibitors Download PDF

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Publication number
HUE028082T2
HUE028082T2 HUE10822550A HUE10822550A HUE028082T2 HU E028082 T2 HUE028082 T2 HU E028082T2 HU E10822550 A HUE10822550 A HU E10822550A HU E10822550 A HUE10822550 A HU E10822550A HU E028082 T2 HUE028082 T2 HU E028082T2
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HU
Hungary
Prior art keywords
ring
mmol
nitrogen
oxygen
sulfur
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HUE10822550A
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English (en)
Hungarian (hu)
Inventor
Joseph Arndt
Timothy Chan
Kevin Guckian
Gnanasambandam Kumaravel
Wen-Cherng Lee
Edward Yin-Shiang Lin
Daniel Scott
Lihong Sun
Jermaine Thomas
Vloten Kurt Van
Deping Wang
Lei Zhang
Daniel Erlanson
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Millennium Pharm Inc
Sunesis Pharmaceuticals Inc
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Application filed by Millennium Pharm Inc, Sunesis Pharmaceuticals Inc filed Critical Millennium Pharm Inc
Publication of HUE028082T2 publication Critical patent/HUE028082T2/en

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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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