HUE027837T2 - Adjuvant use of influenza virus and oil-in-water emulsion to induce CD4 T-cell and / or enhanced B-cell cellular response - Google Patents
Adjuvant use of influenza virus and oil-in-water emulsion to induce CD4 T-cell and / or enhanced B-cell cellular response Download PDFInfo
- Publication number
- HUE027837T2 HUE027837T2 HUE06723805A HUE06723805A HUE027837T2 HU E027837 T2 HUE027837 T2 HU E027837T2 HU E06723805 A HUE06723805 A HU E06723805A HU E06723805 A HUE06723805 A HU E06723805A HU E027837 T2 HUE027837 T2 HU E027837T2
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- Prior art keywords
- influenza
- vaccine
- oil
- adjuvanted
- mpl
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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- Biophysics (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0506000A GB0506000D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0505998A GB0505998D0 (en) | 2005-03-23 | 2005-03-23 | Novel compositions |
| GB0506004A GB0506004D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0506001A GB0506001D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0505989A GB0505989D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0510589A GB0510589D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0510596A GB0510596D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510598A GB0510598D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510593A GB0510593D0 (en) | 2005-05-24 | 2005-05-24 | Novel compositions |
| GB0510591A GB0510591D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0603788A GB0603788D0 (en) | 2006-02-24 | 2006-02-24 | Novel composition |
| GB0603790A GB0603790D0 (en) | 2006-02-24 | 2006-02-24 | Composition |
| GB0603789A GB0603789D0 (en) | 2006-02-24 | 2006-02-24 | Novel use |
Publications (1)
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| HUE027837T2 true HUE027837T2 (en) | 2016-11-28 |
Family
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| HUE06723805A HUE027837T2 (en) | 2005-03-23 | 2006-03-21 | Adjuvant use of influenza virus and oil-in-water emulsion to induce CD4 T-cell and / or enhanced B-cell cellular response |
Country Status (24)
| Country | Link |
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| US (5) | US20080171063A1 (OSRAM) |
| EP (4) | EP1861120B1 (OSRAM) |
| JP (4) | JP5770414B2 (OSRAM) |
| KR (5) | KR20160064249A (OSRAM) |
| AR (3) | AR052625A1 (OSRAM) |
| AU (3) | AU2006226543B2 (OSRAM) |
| CA (3) | CA2602456A1 (OSRAM) |
| CY (1) | CY1117874T1 (OSRAM) |
| DK (1) | DK1861120T3 (OSRAM) |
| EA (3) | EA011393B1 (OSRAM) |
| ES (1) | ES2585810T3 (OSRAM) |
| HR (1) | HRP20160816T1 (OSRAM) |
| HU (1) | HUE027837T2 (OSRAM) |
| IL (3) | IL185897A (OSRAM) |
| MA (3) | MA29715B1 (OSRAM) |
| MX (3) | MX2007011756A (OSRAM) |
| NO (3) | NO20074638L (OSRAM) |
| NZ (2) | NZ561822A (OSRAM) |
| PE (3) | PE20061300A1 (OSRAM) |
| PL (1) | PL1861120T3 (OSRAM) |
| PT (1) | PT1861120T (OSRAM) |
| SI (1) | SI1861120T1 (OSRAM) |
| TW (3) | TW200722101A (OSRAM) |
| WO (3) | WO2006100110A1 (OSRAM) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE279943T1 (de) * | 1999-02-26 | 2004-11-15 | Chiron Srl | Verbesserung der bakterizidaktivität von neisseria antigenen mit cg enthaltende oligonukleotiden |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| US20100221284A1 (en) * | 2001-05-30 | 2010-09-02 | Saech-Sisches Serumwerk Dresden | Novel vaccine composition |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| KR20160064249A (ko) * | 2005-03-23 | 2016-06-07 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Ｃｄ4 ｔ－세포 및/또는 개선된 ｂ－메모리 세포 반응을 유도하는 인플루엔자 바이러스 및 수중유 에멀젼 애주번트의 용도 |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| DE202006021242U1 (de) * | 2005-11-04 | 2014-01-29 | Novartis Vaccines And Diagnostics S.R.L. | Emulsionen mit freiem wässrigen Phasen Tensid als Adjuvans für Spalt-Grippeimpfstoffe |
| ES2792398T3 (es) * | 2005-11-04 | 2020-11-11 | Seqirus Uk Ltd | Vacunas adyuvantadas con antígenos de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular |
| JP2009514839A (ja) * | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | サイトカイン誘導剤を含むアジュバントインフルエンザワクチン |
| PT1951300E (pt) | 2005-11-04 | 2011-09-05 | Novartis Vaccines & Diagnostic | Modificação do equilíbrio de th1/th2 em vacinas da influenza fragmentadas com adjuvantes |
| FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| EP1991264B1 (en) | 2006-03-07 | 2015-01-07 | Vaxinnate Corporation | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| CA2646349A1 (en) * | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
| KR20090016704A (ko) * | 2006-06-15 | 2009-02-17 | 노파르티스 아게 | 보조제-보존 수회-투여 인플루엔자 접종 요법 |
| PL2043682T3 (pl) * | 2006-07-17 | 2014-09-30 | Glaxosmithkline Biologicals Sa | Szczepionka przeciw grypie |
| SI2422810T1 (sl) * | 2006-07-17 | 2015-01-30 | Glaxosmithkline Biologicals S.A. | Influenčno cepivo |
| CA2583555C (en) * | 2006-07-17 | 2020-01-07 | Glaxosmithkline Biologicals S.A. | Influenza vaccine |
| EP2433648A3 (en) * | 2006-10-12 | 2012-04-04 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising an oil in water emulsion adjuvant |
| US20100183667A1 (en) * | 2006-10-12 | 2010-07-22 | Glaxo Smithkline Biologicals S.A. | Vaccine Comprising an Oil in Water Emulsion Adjuvant |
| GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
| EP1923070A1 (en) * | 2006-11-15 | 2008-05-21 | Intervet International BV | Vaccine for vaccinating feline against influenza virus |
| CN101553252A (zh) * | 2006-12-06 | 2009-10-07 | 诺华有限公司 | 包含来自于四株流感病毒的抗原的疫苗 |
| EP1938835A1 (en) * | 2006-12-29 | 2008-07-02 | Pevion Biotech AG | Non-specific immunostimulating agents |
| EP2129773B1 (en) * | 2007-02-23 | 2013-02-13 | Baylor Research Institute | Therapeutic applications of activation of human antigen-presenting cells through dectin-1 |
| US9452209B2 (en) | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| WO2009046497A1 (en) * | 2007-10-12 | 2009-04-16 | Csl Limited | Method of eliciting an immune response against pandemic influenza virus |
| EP2462949A3 (en) * | 2007-10-19 | 2012-09-05 | Novartis AG | Meningococcal vaccine formulations |
| GB0810305D0 (en) † | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| WO2009071633A1 (en) * | 2007-12-06 | 2009-06-11 | Glaxosmithkline Biologicals S.A. | Influenza composition |
| US8426163B2 (en) * | 2007-12-07 | 2013-04-23 | National Health Research Institutes | Production of lipidated proteins in E. coli |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| CN101998990B (zh) * | 2008-03-18 | 2013-11-27 | 诺华股份有限公司 | 流感病毒疫苗抗原制备方法的改进 |
| SG190562A1 (en) | 2008-04-18 | 2013-06-28 | Vaxinnate Corp | Deletion mutants of flagellin and methods of use |
| GB0905570D0 (en) * | 2009-03-31 | 2009-05-13 | Novartis Ag | Combined vaccines |
| EP2310045A1 (en) * | 2008-06-25 | 2011-04-20 | Novartis AG | Rapid responses to delayed booster immunisations |
| WO2010092476A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
| AU2010212550B2 (en) | 2009-02-10 | 2016-03-10 | Seqirus UK Limited | Influenza vaccines with reduced amounts of squalene |
| AU2015203072B2 (en) * | 2009-02-10 | 2017-05-25 | Seqirus UK Limited | Influenza vaccine regimens for pandemic-associated strains |
| US8287880B2 (en) * | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| US8658176B2 (en) * | 2009-06-22 | 2014-02-25 | National Health Research Institutes | Lipidated tumor-associated antigens and immunotherapeutic compositions |
| EP2289575B1 (de) * | 2009-08-06 | 2017-07-05 | Biotronik VI Patent AG | Medizinisches Implantat enthaltend eine antioxidative Substanz |
| US9878036B2 (en) * | 2009-08-12 | 2018-01-30 | Sigmoid Pharma Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
| EP2308506A1 (en) * | 2009-10-02 | 2011-04-13 | Mucosis B.V. | Adjuvanted intranasal vaccine formulations |
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| GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| SG10201501613SA (en) * | 2009-12-03 | 2015-04-29 | Novartis Ag | Arranging interaction and back pressure chambers for microfluidization |
| SG10201501611QA (en) | 2009-12-03 | 2015-04-29 | Novartis Ag | Circulation of components during microfluidization and/or homogenization emulsions |
| BR112012013425A2 (pt) * | 2009-12-03 | 2020-11-03 | Novartis Ag | filtração hidrofílica durante a fabricação de adjuvantes de vacinas |
| DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
| DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| AU2013202690B2 (en) * | 2009-12-03 | 2016-02-11 | Seqirus UK Limited | Hydrophilic filtration during manufacture of vaccine adjuvants |
| JP5894083B2 (ja) * | 2009-12-22 | 2016-03-23 | サノフィ パストゥール リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ | 免疫原性組成物 |
| JP2013516469A (ja) * | 2010-01-06 | 2013-05-13 | ヴァクシネイト コーポレイション | 高齢者に保護免疫を提供するための方法及び組成物 |
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- 2006-03-21 PT PT67238055T patent/PT1861120T/pt unknown
- 2006-03-21 EP EP06723807A patent/EP1861122A1/en not_active Withdrawn
- 2006-03-21 KR KR1020077024380A patent/KR20070116650A/ko not_active Ceased
- 2006-03-21 KR KR1020137034497A patent/KR101916787B1/ko not_active Expired - Fee Related
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- 2006-03-21 EA EA200701787A patent/EA200701787A1/ru unknown
- 2006-03-21 WO PCT/EP2006/002837 patent/WO2006100110A1/en not_active Ceased
- 2006-03-21 PL PL06723805.5T patent/PL1861120T3/pl unknown
- 2006-03-21 HR HRP20160816TT patent/HRP20160816T1/hr unknown
- 2006-03-21 US US11/909,388 patent/US20080171063A1/en not_active Abandoned
- 2006-03-21 KR KR1020077024383A patent/KR20070116651A/ko not_active Withdrawn
- 2006-03-21 AU AU2006226458A patent/AU2006226458B2/en not_active Ceased
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- 2006-03-21 PE PE2006000311A patent/PE20061300A1/es not_active Application Discontinuation
- 2006-03-21 TW TW095109703A patent/TW200700078A/zh unknown
- 2006-03-21 EP EP06723806A patent/EP1863529A1/en not_active Withdrawn
- 2006-03-21 NZ NZ561823A patent/NZ561823A/en not_active IP Right Cessation
- 2006-03-21 US US11/909,351 patent/US20080181911A1/en not_active Abandoned
- 2006-03-21 KR KR1020077024388A patent/KR20070116652A/ko not_active Ceased
- 2006-03-21 AU AU2006226459A patent/AU2006226459A1/en not_active Abandoned
- 2006-03-21 WO PCT/EP2006/002838 patent/WO2006100111A1/en not_active Ceased
- 2006-03-21 US US11/909,414 patent/US20090081253A1/en not_active Abandoned
- 2006-03-21 CA CA2601022A patent/CA2601022C/en active Active
- 2006-03-21 PE PE2006000312A patent/PE20061428A1/es not_active Application Discontinuation
- 2006-03-21 SI SI200632082A patent/SI1861120T1/sl unknown
- 2006-03-21 CA CA2603180A patent/CA2603180C/en active Active
- 2006-03-23 PE PE2006000334A patent/PE20061387A1/es not_active Application Discontinuation
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2007
- 2007-09-11 IL IL185897A patent/IL185897A/en active IP Right Grant
- 2007-09-11 IL IL185906A patent/IL185906A0/en unknown
- 2007-09-11 IL IL185901A patent/IL185901A0/en unknown
- 2007-09-12 NO NO20074638A patent/NO20074638L/no not_active Application Discontinuation
- 2007-09-12 NO NO20074635A patent/NO20074635L/no not_active Application Discontinuation
- 2007-09-24 MA MA30240A patent/MA29715B1/fr unknown
- 2007-09-24 MA MA30241A patent/MA29342B1/fr unknown
- 2007-09-24 MA MA30238A patent/MA30298B1/fr unknown
- 2007-09-28 NO NO20074930A patent/NO20074930L/no not_active Application Discontinuation
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2011
- 2011-04-28 US US13/096,180 patent/US20110287054A1/en not_active Abandoned
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2014
- 2014-01-31 JP JP2014016254A patent/JP2014129359A/ja active Pending
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2016
- 2016-08-05 CY CY20161100772T patent/CY1117874T1/el unknown
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